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ONTOLOGY REPORT - ANNOTATIONS


Term:temporal lobe epilepsy
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Accession:DOID:3328 term browser browse the term
Definition:A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the temporal lobe, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic (i.e., related to an identified disease process or lesion). (From Adams et al., Principles of Neurology, 6th ed, p321)
Synonyms:exact_synonym: Lateral Temporal Epilepsies;   Lateral Temporal Epilepsy;   TLE;   Temporal Lobe Epilepsies;   Uncinate Epilepsies;   childhood benign psychomotor epilepsy;   uncinate epilepsy
 primary_id: MESH:D004833
 alt_id: RDO:0002687
 xref: OMIM:PS600512
For additional species annotation, visit the Alliance of Genome Resources.


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temporal lobe epilepsy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:1358367
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B JBrowse link 4 22,225,123 22,307,577 RGD:1598560
G Actb actin, beta JBrowse link 12 13,715,843 13,718,813 RGD:5147998
G Add1 adducin 1 JBrowse link 14 81,367,466 81,426,610 RGD:5147998
G Adk adenosine kinase JBrowse link 15 3,033,535 3,435,888 RGD:6482302
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:8549466
G Ak2 adenylate kinase 2 JBrowse link 5 147,185,474 147,204,050 RGD:11100024
G Aqp4 aquaporin 4 JBrowse link 18 6,766,009 6,782,757 RGD:5148036
G Avp arginine vasopressin JBrowse link 3 123,117,482 123,119,460 RGD:1579871
G Bdkrb1 bradykinin receptor B1 JBrowse link 6 129,437,423 129,441,553 RGD:11554173
G Bdkrb2 bradykinin receptor B2 JBrowse link 6 129,399,468 129,429,676 RGD:11554173
G Cabp1 calcium binding protein 1 JBrowse link 12 47,185,449 47,209,785 RGD:14399955
G Cacna1a calcium voltage-gated channel subunit alpha1 A JBrowse link 19 25,453,236 25,749,550 RGD:10054441
G Casp2 caspase 2 JBrowse link 4 71,652,358 71,670,228 RGD:4107076
G Cdc42 cell division cycle 42 JBrowse link 5 155,690,267 155,728,385 RGD:5688272
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:11554173
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:5508845
G Crhbp corticotropin releasing hormone binding protein JBrowse link 2 25,141,471 25,153,334 RGD:5508845
G Cxcr4 C-X-C motif chemokine receptor 4 JBrowse link 13 45,314,952 45,318,856 RGD:13463105
G Cyfip1 cytoplasmic FMR1 interacting protein 1 JBrowse link 1 114,258,773 114,347,138 RGD:11568065
G Dbn1 drebrin 1 JBrowse link 17 9,679,511 9,693,878 RGD:10398806
G Dcx doublecortin JBrowse link X 115,098,675 115,175,515 RGD:12904713
G Dlg4 discs large MAGUK scaffold protein 4 JBrowse link 10 56,625,845 56,655,543 RGD:5147998
G Dtnbp1 dystrobrevin binding protein 1 JBrowse link 17 20,090,136 20,182,332 RGD:11251761
G Foxo3 forkhead box O3 JBrowse link 20 46,428,078 46,519,156 RGD:10402198
G Fyn FYN proto-oncogene, Src family tyrosine kinase JBrowse link 20 44,436,354 44,630,316 RGD:5147998
G Glud1 glutamate dehydrogenase 1 JBrowse link 16 10,661,486 10,695,557 RGD:6484554
G Glul glutamate-ammonia ligase JBrowse link 13 71,331,052 71,340,207 RGD:2301554
RGD:13592920
RGD:2301555
G Grik5 glutamate ionotropic receptor kainate type subunit 5 JBrowse link 1 81,885,516 81,946,731 RGD:2316538
RGD:5147998
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 4 169,541,620 170,000,216 RGD:13432039
G Grm1 glutamate metabotropic receptor 1 JBrowse link 1 4,753,141 5,165,859 RGD:5147998
RGD:11554173
G Grm2 glutamate metabotropic receptor 2 JBrowse link 8 115,344,999 115,358,628 RGD:11554173
G Grm3 glutamate metabotropic receptor 3 JBrowse link 4 21,316,761 21,567,561 RGD:11554173
G Grm4 glutamate metabotropic receptor 4 JBrowse link 20 6,745,682 6,791,521 RGD:11554173
G Grm5 glutamate metabotropic receptor 5 JBrowse link 1 151,207,846 151,785,038 RGD:11554173
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 JBrowse link 2 50,099,576 50,499,799 RGD:9686145
RGD:9686146
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:9590259
G Kcna1 potassium voltage-gated channel subfamily A member 1 JBrowse link 4 159,190,781 159,192,526 RGD:13592920
G Kcnab1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 JBrowse link 2 155,555,798 156,011,438 RGD:9743959
G Kcnc4 potassium voltage-gated channel subfamily C member 4 JBrowse link 2 210,220,908 210,241,447 RGD:11554173
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:11554173
G Map2 microtubule-associated protein 2 JBrowse link 9 73,204,753 73,462,965 RGD:6483080
G Mapt microtubule-associated protein tau JBrowse link 10 92,289,002 92,386,517 RGD:13800901
G Mbp myelin basic protein JBrowse link 18 79,326,738 79,437,310 RGD:7327195
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:8547829
G Mt-co3 mitochondrially encoded cytochrome c oxidase III JBrowse link MT 8,599 9,382 RGD:11554173
G Mt-nd1 mitochondrially encoded NADH dehydrogenase 1 JBrowse link MT 2,740 3,694 RGD:5490286
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:10041000
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:5147998
G Npy neuropeptide Y JBrowse link 4 79,557,856 79,565,059 RGD:10434563
RGD:11554173
G Npy1r neuropeptide Y receptor Y1 JBrowse link 16 24,779,480 24,789,131 RGD:1642609
G Npy2r neuropeptide Y receptor Y2 JBrowse link 2 181,528,949 181,538,145 RGD:1642609
RGD:11554173
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase JBrowse link 10 91,879,608 91,986,242 RGD:5147998
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:5147998
G P2rx4 purinergic receptor P2X 4 JBrowse link 12 39,308,022 39,325,673 RGD:11554173
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:11554173
G Pdyn prodynorphin JBrowse link 3 122,194,327 122,206,671 RGD:1358556
G Pgf placental growth factor JBrowse link 6 108,994,016 109,004,598 RGD:6483774
G Prickle1 prickle planar cell polarity protein 1 JBrowse link 7 134,702,964 134,799,437 RGD:9686146
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 JBrowse link 4 49,941,046 50,140,764 RGD:9589829
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 JBrowse link 8 97,277,250 97,405,095 RGD:10003135
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:2317926
RGD:13207524
G Rgma repulsive guidance molecule BMP co-receptor a JBrowse link 1 134,699,053 134,742,512 RGD:9850144
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:12859046
G Slc12a2 solute carrier family 12 member 2 JBrowse link 18 52,917,124 52,985,281 RGD:11554173
G Slc12a5 solute carrier family 12 member 5 JBrowse link 3 161,433,303 161,465,078 RGD:11554173
G Slc1a1 solute carrier family 1 member 1 JBrowse link 1 246,955,017 247,035,159 RGD:11554173
G Slc6a1 solute carrier family 6 member 1 JBrowse link 4 146,258,842 146,292,176 RGD:1643206
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:11554173
G Tek TEK receptor tyrosine kinase JBrowse link 5 113,725,717 113,852,799 RGD:11554173
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:11554173
G Vdac2 voltage-dependent anion channel 2 JBrowse link 15 2,634,622 2,648,548 RGD:10003053
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:11554173
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:11554173
Familial Temporal Epilepsy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cpa6 carboxypeptidase A6 JBrowse link 5 8,215,443 8,574,655 RGD:8554872
familial temporal lobe epilepsy 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lgi1 leucine-rich, glioma inactivated 1 JBrowse link 1 256,955,944 256,996,835 RGD:7240710
RGD:8554872
G Mical1 microtubule associated monooxygenase, calponin and LIM domain containing 1 JBrowse link 20 46,199,981 46,211,930 RGD:11554173
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:11554173
RGD:8554872
familial temporal lobe epilepsy 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cpa6 carboxypeptidase A6 JBrowse link 5 8,215,443 8,574,655 RGD:8554872
familial temporal lobe epilepsy 3 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:11041150
RGD:8554872
familial temporal lobe epilepsy 5 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cpa6 carboxypeptidase A6 JBrowse link 5 8,215,443 8,574,655 RGD:7240710
RGD:8554872
familial temporal lobe epilepsy 7 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:8554872
RGD:7240710
familial temporal lobe epilepsy 8 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gal galanin and GMAP prepropeptide JBrowse link 1 218,653,059 218,657,922 RGD:8554872
RGD:7240710

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  disease 15503
    disease of anatomical entity 14857
      nervous system disease 10273
        central nervous system disease 8410
          brain disease 7763
            epilepsy 1100
              focal epilepsy 131
                temporal lobe epilepsy 78
                  Familial Temporal Epilepsy + 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.