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ONTOLOGY REPORT - ANNOTATIONS


Term:osteosarcoma
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Accession:DOID:3347 term browser browse the term
Definition:A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
Synonyms:exact_synonym: OSRC;   OSTEOBLASTIC OSTEOSARCOMA;   osteogenic sarcoma;   osteogenic sarcomas;   osteoid sarcoma;   osteosarcoma tumor;   osteosarcoma tumors;   osteosarcomas;   skeletal sarcoma
 narrow_synonym: osteosarcoma, somatic
 primary_id: MESH:D012516
 alt_id: OMIM:259500
 xref: GARD:7284;   NCI:C9145;   ORDO:668
For additional species annotation, visit the Alliance of Genome Resources.


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osteosarcoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap12 A kinase (PRKA) anchor protein (gravin) 12 JBrowse link 10 4,266,329 4,359,471 RGD:5147850
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:8554872
G Bcor BCL6 interacting corepressor JBrowse link X 12,036,737 12,160,516 RGD:11554173
G Bmi1 Bmi1 polycomb ring finger oncogene JBrowse link 2 18,677,018 18,686,629 RGD:11554173
G Brca2 breast cancer 2, early onset JBrowse link 5 150,522,297 150,570,147 RGD:1599505
G Brd4 bromodomain containing 4 JBrowse link 17 32,196,272 32,284,743 RGD:11554173
G Ccnb3 cyclin B3 JBrowse link X 6,979,652 7,041,635 RGD:11554173
G Cdc5l cell division cycle 5-like (S. pombe) JBrowse link 17 45,391,887 45,433,707 RGD:10047050
G Cdkn2a cyclin dependent kinase inhibitor 2A JBrowse link 4 89,274,473 89,294,619 RGD:8554872
G Chek2 checkpoint kinase 2 JBrowse link 5 110,839,800 110,874,140 RGD:7240710
RGD:8554872
RGD:11554173
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 JBrowse link 10 17,723,228 17,725,674 RGD:5147850
G Dhfr dihydrofolate reductase JBrowse link 13 92,354,783 92,389,053 RGD:11554173
G Egfr epidermal growth factor receptor JBrowse link 11 16,752,203 16,913,907 RGD:11554173
G Egr1 early growth response 1 JBrowse link 18 34,861,207 34,864,956 RGD:5131662
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha JBrowse link 12 78,862,072 78,887,010 RGD:11554173
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 JBrowse link 7 19,344,067 19,356,524 RGD:13207418
G Ercc2 excision repair cross-complementing rodent repair deficiency, complementation group 2 JBrowse link 7 19,382,017 19,395,694 RGD:8554872
G Esrra estrogen related receptor, alpha JBrowse link 19 6,910,977 6,922,048 RGD:11554173
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 6 47,530,274 47,595,270 RGD:11554173
G Folr1 folate receptor 1 (adult) JBrowse link 7 101,858,331 101,870,788 RGD:11554173
G Grm4 glutamate receptor, metabotropic 4 JBrowse link 17 27,422,387 27,513,826 RGD:11554173
G Gstm3 glutathione S-transferase, mu 3 JBrowse link 3 107,963,696 107,969,174 RGD:5135042
G Gstp1 glutathione S-transferase, pi 1 JBrowse link 19 4,035,411 4,037,912 RGD:11554173
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 JBrowse link X 152,001,896 152,004,442 RGD:13792789
G Il3 interleukin 3 JBrowse link 11 54,265,085 54,267,279 RGD:2317666
G Jun jun proto-oncogene JBrowse link 4 95,049,036 95,052,222 RGD:11554173
G Kcnh1 potassium voltage-gated channel, subfamily H (eag-related), member 1 JBrowse link 1 192,189,144 192,510,159 RGD:11554173
G Lox lysyl oxidase JBrowse link 18 52,516,060 52,529,867 RGD:11554173
G Lzic leucine zipper and CTNNBIP1 domain containing JBrowse link 4 149,485,185 149,503,516 RGD:2314410
G Met met proto-oncogene JBrowse link 6 17,463,349 17,573,980 RGD:11554173
G Mir106b microRNA 106b JBrowse link 5 138,165,737 138,165,818 RGD:11554173
G Mir130b microRNA 130b JBrowse link 16 17,124,061 17,124,142 RGD:11554173
G Mir302b microRNA 302b JBrowse link 3 127,545,228 127,545,301 RGD:11554173
G Mir328 microRNA 328 JBrowse link 8 105,308,364 105,308,460 RGD:11554173
G Mir93 microRNA 93 JBrowse link 5 138,165,523 138,165,610 RGD:11554173
G Mmp2 matrix metallopeptidase 2 JBrowse link 8 92,827,290 92,853,421 RGD:11554173
G Mst1r macrophage stimulating 1 receptor (c-met-related tyrosine kinase) JBrowse link 9 107,906,858 107,920,383 RGD:11554173
G Mthfr methylenetetrahydrofolate reductase JBrowse link 4 148,039,077 148,059,562 RGD:6893634
G Myc myelocytomatosis oncogene JBrowse link 15 61,985,341 61,990,361 RGD:11554173
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 16 38,248,349 38,294,849 RGD:11554173
G Phlda2 pleckstrin homology like domain, family A, member 2 JBrowse link 7 143,501,545 143,503,145 RGD:11554173
G Prame preferentially expressed antigen in melanoma JBrowse link X 135,612,954 135,627,705 RGD:11535057
G Prdx2 peroxiredoxin 2 JBrowse link 8 84,969,622 84,974,811 RGD:11554173
G Pth parathyroid hormone JBrowse link 7 113,385,576 113,388,672 RGD:7242897
G Rb1 RB transcriptional corepressor 1 JBrowse link 14 73,192,858 73,325,951 RGD:7240710
RGD:8554872
RGD:11554173
G Rfc1 replication factor C (activator 1) 1 JBrowse link 5 65,261,852 65,338,617 RGD:11554173
G Rgs1 regulator of G-protein signaling 1 JBrowse link 1 144,244,669 144,249,104 RGD:11554173
G Runx2 runt related transcription factor 2 JBrowse link 17 44,495,987 44,814,797 RGD:11554173
G Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1 JBrowse link 11 75,410,029 75,422,623 RGD:8633656
RGD:8655561
G Sirt1 sirtuin 1 JBrowse link 10 63,319,005 63,339,035 RGD:11554173
G Taf15 TATA-box binding protein associated factor 15 JBrowse link 11 83,473,073 83,506,743 RGD:11554173
G Topors topoisomerase I binding, arginine/serine-rich JBrowse link 4 40,259,606 40,269,841 RGD:11554173
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:7240710
RGD:8554872
RGD:11554173
G Tsc2 TSC complex subunit 2 JBrowse link 17 24,595,816 24,632,676 RGD:8554872
G Vegfa vascular endothelial growth factor A JBrowse link 17 46,016,993 46,032,377 RGD:11554173
G Wt1 Wilms tumor 1 homolog JBrowse link 2 105,126,529 105,173,614 RGD:11554173
G Zw10 zw10 kinetochore protein JBrowse link 9 49,055,576 49,078,775 RGD:11554173

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13044
    disease of cellular proliferation 5709
      cancer 4150
        cell type cancer 3082
          sarcoma 234
            bone sarcoma 80
              osteosarcoma 57
                Oslam syndrome 0
                Premature Aging, Okamoto Type 0
                Retinoblastoma-Related Osteosarcoma 0
                adult extraosseous osteosarcoma 0
                bone leiomyosarcoma 0
                bone osteosarcoma + 0
                breast osteosarcoma 0
                central nervous system osteosarcoma 0
                chondroblastic osteosarcoma 0
                extraosseous osteosarcoma + 0
                juxtacortical osteosarcoma + 0
                kidney osteogenic sarcoma 0
                liposarcoma of bone 0
                localized osteosarcoma 0
                malignant fibrous histiocytoma of bone 0
                metachronous osteosarcoma of the bone 0
                pediatric osteosarcoma 0
Path 2
Term Annotations click to browse term
  disease 13044
    disease of anatomical entity 12695
      musculoskeletal system disease 5141
        connective tissue disease 3619
          bone disease 3084
            Bone Neoplasms 1269
              bone cancer 1256
                bone sarcoma 80
                  osteosarcoma 57
                    Oslam syndrome 0
                    Premature Aging, Okamoto Type 0
                    Retinoblastoma-Related Osteosarcoma 0
                    adult extraosseous osteosarcoma 0
                    bone leiomyosarcoma 0
                    bone osteosarcoma + 0
                    breast osteosarcoma 0
                    central nervous system osteosarcoma 0
                    chondroblastic osteosarcoma 0
                    extraosseous osteosarcoma + 0
                    juxtacortical osteosarcoma + 0
                    kidney osteogenic sarcoma 0
                    liposarcoma of bone 0
                    localized osteosarcoma 0
                    malignant fibrous histiocytoma of bone 0
                    metachronous osteosarcoma of the bone 0
                    pediatric osteosarcoma 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.