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ONTOLOGY REPORT - ANNOTATIONS


Term:cutaneous Paget's disease
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Accession:DOID:3450 term browser browse the term
Definition:A rare cutaneous neoplasm that occurs in the elderly. It develops more frequently in women and predominantly involves apocrine gland-bearing areas, especially the vulva, scrotum, and perianal areas. The lesions develop as erythematous scaly patches that progress to crusted, pruritic, erythematous plaques. The clinical differential diagnosis includes squamous cell carcinoma in situ and superficial fungal infection. It is generally thought to be an adenocarcinoma of the epidermis, from which it extends into the contiguous epithelium of hair follicles and eccrine sweat ducts. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1478)
Synonyms:exact_synonym: Extra Mammary Paget Disease;   Extra Mammary Paget's Disease;   Extra-Mammary Pagets Disease;   Extramammary Paget's Disease;   Extramammary Pagets Disease;   Paget Disease, Extramammary;   Paget's disease of skin;   cutaneous Paget disease
 primary_id: MESH:D010145
 alt_id: RDO:0006263
 xref: NCI:C3302
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cutaneous Paget's disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha JBrowse link 2 118,831,350 118,861,456 RGD:14402410

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15610
    disease of cellular proliferation 5827
      Neoplasms by Histologic Type 3641
        Glandular and Epithelial Neoplasms 2111
          Neoplasms, Ductal, Lobular, and Medullary 254
            cutaneous Paget's disease 1
              anal Paget's disease + 0
              anal canal Paget's disease 0
              perianal skin Paget's disease 0
              scrotum Paget's disease 0
              vulval Paget's disease 0
Path 2
Term Annotations click to browse term
  disease 15610
    disease of anatomical entity 14968
      nervous system disease 10400
        sensory system disease 4770
          skin disease 2495
            Skin Neoplasms 227
              skin cancer 115
                skin carcinoma 50
                  cutaneous Paget's disease 1
                    anal Paget's disease + 0
                    anal canal Paget's disease 0
                    perianal skin Paget's disease 0
                    scrotum Paget's disease 0
                    vulval Paget's disease 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.