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ONTOLOGY REPORT - ANNOTATIONS


Term:choriocarcinoma
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Accession:DOID:3594 term browser browse the term
Definition:A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).
Synonyms:exact_synonym: Choriocarcinomas;   Chorioepithelioma
 primary_id: MESH:D002822;   RDO:0005207
 xref: GARD:6059;   ICD10CM:C58;   NCI:C2948
For additional species annotation, visit the Alliance of Genome Resources.


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choriocarcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:2289339
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:2290454
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:2290454
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:2292200
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:2292200
G Timp3 TIMP metallopeptidase inhibitor 3 JBrowse link 7 23,543,125 23,594,170 RGD:2290418

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15603
    disease of cellular proliferation 5804
      Neoplastic Pregnancy Complications 17
        trophoblastic neoplasm 17
          choriocarcinoma 6
            adult central nervous system choriocarcinoma 0
            choriocarcinoma of ovary + 0
            choriocarcinoma of the testis + 0
            gestational choriocarcinoma + 0
            non-gestational choriocarcinoma 0
            pediatric CNS choriocarcinoma 0
            placental site trophoblastic tumor 0
            pulmonary artery choriocarcinoma 0
            uterine corpus choriocarcinoma + 0
Path 2
Term Annotations click to browse term
  disease 15603
    disease of anatomical entity 14934
      Urogenital Diseases 3981
        Female Urogenital Diseases and Pregnancy Complications 1725
          Female Urogenital Diseases 1466
            female reproductive system disease 1462
              Female Genital Neoplasms 565
                female reproductive organ cancer 402
                  uterine cancer 275
                    placenta cancer 6
                      choriocarcinoma 6
                        adult central nervous system choriocarcinoma 0
                        choriocarcinoma of ovary + 0
                        choriocarcinoma of the testis + 0
                        gestational choriocarcinoma + 0
                        non-gestational choriocarcinoma 0
                        pediatric CNS choriocarcinoma 0
                        placental site trophoblastic tumor 0
                        pulmonary artery choriocarcinoma 0
                        uterine corpus choriocarcinoma + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.