Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:olfactory neuroblastoma
go back to main search page
Accession:DOID:369 term browser browse the term
Definition:A malignant olfactory neuroblastoma arising from the olfactory epithelium of the superior nasal cavity and cribriform plate. It is uncommon (3% of nasal tumors) and rarely is associated with the production of excess hormones (e.g., SIADH, Cushing Syndrome). It has a high propensity for multiple local recurrences and bony metastases. (From Holland et al., Cancer Medicine, 3rd ed, p1245; J Laryngol Otol 1998 Jul;112(7):628-33)
Synonyms:exact_synonym: Aesthesioneuroblastoma;   Aesthesioneuroblastomas;   Asthesioneuroblastoma;   Esthesioneuroblastoma;   Esthesioneuroblastomas;   Esthesioneuroepithelioma;   Olfactory Esthesioneuroblastomas;   Olfactory Neuroblastomas;   Paranasal Sinus Nasal Cavity Esthesioneuroblastoma;   olfactory esthesioneuroblastoma;   paranasal sinus Olfactory neuroblastoma
 primary_id: MESH:D018304
 alt_id: RDO:0007173
 xref: GARD:2197;   NCI:C3789;   NCI:C6016
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
olfactory neuroblastoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HIF1A hypoxia inducible factor 1 subunit alpha severity IEP protein:increased expression:neuroblastoma (human) RGD PMID:18431543 RGD:8694471 NCBI chr14:61,695,513...61,748,259
Ensembl chr14:61,695,513...61,748,259
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18864
    disease of cellular proliferation 6853
      Neoplasms by Site 6120
        Nervous System Neoplasms 1894
          peripheral nervous system neoplasm 130
            autonomic nervous system neoplasm 86
              neuroblastoma 86
                olfactory neuroblastoma 1
                  nasal cavity olfactory neuroblastoma 0
Path 2
Term Annotations click to browse term
  disease 18864
    disease of anatomical entity 17349
      nervous system disease 13439
        Nervous System Neoplasms 1894
          Central Nervous System Neoplasms 1557
            central nervous system cancer 1502
              brain cancer 1485
                supratentorial cancer 1224
                  cerebrum cancer 1196
                    astrocytoma 1194
                      astroblastoma 378
                        Primitive Neuroectodermal Tumors 150
                          Primitive Peripheral Neuroectodermal Tumors 87
                            neuroblastoma 86
                              olfactory neuroblastoma 1
                                nasal cavity olfactory neuroblastoma 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.