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ONTOLOGY REPORT - ANNOTATIONS


Term:lung adenocarcinoma
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Accession:DOID:3910 term browser browse the term
Definition:A lung cancer that derives_from epithelial cells of glandular origin. (DO)
Synonyms:exact_synonym: Adenocarcinoma of lung, somatic;   adenocarcinoma of lung;   bronchogenic lung adenocarcinoma;   nonsmall cell adenocarcinoma;   pulmonary adenocarcinoma
 primary_id: MESH:D000077192
 xref: GARD:5742;   NCI:C27745;   NCI:C3512
For additional species annotation, visit the Alliance of Genome Resources.


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lung adenocarcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abce1 ATP binding cassette subfamily E member 1 JBrowse link 19 31,867,960 31,892,863 RGD:11046260
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:8554872
G Alk ALK receptor tyrosine kinase JBrowse link 6 22,696,415 23,203,791 RGD:8554872
G Anapc2 anaphase promoting complex subunit 2 JBrowse link 3 2,490,496 2,502,247 RGD:14696682
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:8554872
G Araf A-Raf proto-oncogene, serine/threonine kinase JBrowse link X 1,369,534 1,391,603 RGD:8554872
G B2m beta-2 microglobulin JBrowse link 3 114,087,287 114,093,311 RGD:8554872
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:8554872
G Cadm1 cell adhesion molecule 1 JBrowse link 8 51,858,906 52,200,591 RGD:2289096
G Cbx5 chromobox 5 JBrowse link 7 144,819,673 144,865,014 RGD:9586743
G Cbx7 chromobox 7 JBrowse link 7 121,136,067 121,153,503 RGD:9587356
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:11536846
RGD:13434927
G Cd44 CD44 molecule (Indian blood group) JBrowse link 3 92,695,083 92,783,820 RGD:2289345
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:1599556
G Cdk12 cyclin-dependent kinase 12 JBrowse link 10 86,157,186 86,210,657 RGD:8554872
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:8554872
RGD:13464277
G Cdk6 cyclin-dependent kinase 6 JBrowse link 4 27,781,728 27,969,653 RGD:13464325
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:8554872
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:8554872
G Dnmt3a DNA methyltransferase 3 alpha JBrowse link 6 28,205,375 28,346,052 RGD:8554872
G Dnmt3b DNA methyltransferase 3 beta JBrowse link 3 149,131,541 149,170,061 RGD:9589086
G E2f1 E2F transcription factor 1 JBrowse link 3 150,062,895 150,073,721 RGD:13464334
G E2f3 E2F transcription factor 3 JBrowse link 17 36,334,136 36,408,831 RGD:13464341
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:11538684
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:8554872
G Ehmt2 euchromatic histone lysine methyltransferase 2 JBrowse link 20 4,576,033 4,592,980 RGD:9589170
G Epha5 EPH receptor A5 JBrowse link 14 25,589,312 25,958,258 RGD:8554872
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:8554872
G Fbxw7 F-box and WD repeat domain containing 7 JBrowse link 2 184,230,191 184,309,805 RGD:8554872
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:8554872
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:8554872
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:11561933
G Gjb2 gap junction protein, beta 2 JBrowse link 15 37,377,313 37,394,494 RGD:11568669
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:8554872
G Hoxb7 homeo box B7 JBrowse link 10 84,135,224 84,138,642 RGD:10402176
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:8554872
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 JBrowse link 9 71,882,108 71,911,645 RGD:8554872
G Igf2r insulin-like growth factor 2 receptor JBrowse link 1 48,176,095 48,264,482 RGD:1298968
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:1600465
RGD:8554872
G Lrrc56 leucine rich repeat containing 56 JBrowse link 1 214,182,232 214,197,184 RGD:8554872
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:8554872
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:8554872
G Muc1 mucin 1, cell surface associated JBrowse link 2 188,543,137 188,547,874 RGD:5131260
G Muc4 mucin 4, cell surface associated JBrowse link 11 71,242,973 71,285,217 RGD:5131208
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:7207787
RGD:8554872
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:8554872
G Nras NRAS proto-oncogene, GTPase JBrowse link 2 205,553,119 205,563,716 RGD:8554872
G Pacrg parkin coregulated JBrowse link 1 50,070,273 50,491,323 RGD:8554872
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha JBrowse link 2 118,831,350 118,861,456 RGD:8554872
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:13464334
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha JBrowse link 1 60,717,386 60,736,629 RGD:8554872
G Prame preferentially expressed antigen in melanoma JBrowse link X 106,082,984 106,091,256 RGD:11535020
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:8554872
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 12 40,895,515 40,955,999 RGD:8554872
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 4 147,532,040 147,592,769 RGD:8554872
G Rarb retinoic acid receptor, beta JBrowse link 15 9,915,223 10,262,599 RGD:13464334
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:8554872
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase JBrowse link 20 33,100,190 33,323,544 RGD:8554872
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N JBrowse link 6 128,073,344 128,080,878 RGD:5147446
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:8554872
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 JBrowse link 3 122,696,125 122,703,734 RGD:10768834
G Snrpe small nuclear ribonucleoprotein polypeptide E JBrowse link 13 50,252,707 50,258,951 RGD:10768834
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 6 3,105,443 3,182,977 RGD:8554872
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:8554872
G Sult1a1 sulfotransferase family 1A member 1 JBrowse link 1 198,100,586 198,104,106 RGD:1581441
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:8554872
G U2af1 U2 small nuclear RNA auxiliary factor 1 JBrowse link 20 10,396,652 10,407,564 RGD:8554872
G Wrap53 WD repeat containing, antisense to TP53 JBrowse link 10 56,169,024 56,185,800 RGD:21081522
bronchiolo-alveolar adenocarcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:13434930
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:4140940
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:5131465
RGD:11075076
RGD:5131630
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:5131942
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:4140940
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:11075076
G Mir130a microRNA 130a JBrowse link 3 72,141,037 72,141,124 RGD:11554173
G Mir144 microRNA 144 JBrowse link 10 65,291,365 65,291,447 RGD:11554173
G Mir19a microRNA 19a JBrowse link 15 100,180,162 100,180,243 RGD:11554173
G Mir345 microRNA 345 JBrowse link 6 132,748,968 132,749,063 RGD:11554173
G Mir497 microRNA 497 JBrowse link 10 56,844,977 56,845,045 RGD:11554173
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:11075076

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15610
    disease of cellular proliferation 5827
      cancer 4161
        cell type cancer 3057
          carcinoma 1914
            lung carcinoma 330
              lung adenocarcinoma 76
                bronchiolo-alveolar adenocarcinoma + 12
                lung acinar adenocarcinoma 0
                lung clear cell carcinoma 0
                lung mucinous cystadenocarcinoma 0
                lung occult adenocarcinoma 0
                lung papillary adenocarcinoma 0
                mucinous lung adenocarcinoma 0
                pulmonary adenocarcinoma in situ 0
                signet ring lung adenocarcinoma 0
                solid adenocarcinoma with mucin production 0
Path 2
Term Annotations click to browse term
  disease 15610
    disease of anatomical entity 14968
      respiratory system disease 2463
        thoracic disease 1578
          Thoracic Neoplasms 1023
            Respiratory Tract Neoplasms 667
              respiratory system cancer 388
                lung cancer 379
                  bronchus cancer 324
                    bronchus carcinoma 324
                      lung non-small cell carcinoma 288
                        lung adenocarcinoma 76
                          bronchiolo-alveolar adenocarcinoma + 12
                          lung acinar adenocarcinoma 0
                          lung clear cell carcinoma 0
                          lung mucinous cystadenocarcinoma 0
                          lung occult adenocarcinoma 0
                          lung papillary adenocarcinoma 0
                          mucinous lung adenocarcinoma 0
                          pulmonary adenocarcinoma in situ 0
                          signet ring lung adenocarcinoma 0
                          solid adenocarcinoma with mucin production 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.