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ONTOLOGY REPORT - ANNOTATIONS


Term:trophoblastic neoplasm
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Accession:DOID:4085 term browser browse the term
Definition:Trophoblastic growth, which may be gestational or nongestational in origin. Trophoblastic neoplasia resulting from pregnancy is often described as gestational trophoblastic disease to distinguish it from germ cell tumors which frequently show trophoblastic elements, and from the trophoblastic differentiation which sometimes occurs in a wide variety of epithelial cancers. Gestational trophoblastic growth has several forms, including HYDATIDIFORM MOLE and CHORIOCARCINOMA. (From Holland et al., Cancer Medicine, 3d ed, p1691)
Synonyms:exact_synonym: Trophoblast Cancer;   Trophoblast Cancers;   Trophoblast Neoplasm;   Trophoblast Neoplasms;   Trophoblast Tumor;   Trophoblast Tumors;   Trophoblastic Cancer;   Trophoblastic Cancers;   Trophoblastic Tumor;   Trophoblastic Tumors;   trophoblastic neoplasms
 primary_id: MESH:D014328;   RDO:0003705
 xref: NCI:C3422
For additional species annotation, visit the Alliance of Genome Resources.


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trophoblastic neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ang angiogenin JBrowse link 15 28,022,926 28,028,636 RGD:2325706
G Kiss1 KiSS-1 metastasis-suppressor JBrowse link 13 50,529,506 50,537,603 RGD:2292132
choriocarcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:2289339
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:2290454
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:2290454
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:2292200
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:2292200
G Timp3 TIMP metallopeptidase inhibitor 3 JBrowse link 7 23,543,125 23,594,170 RGD:2290418
gestational trophoblastic neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ncr1 natural cytotoxicity triggering receptor 1 JBrowse link 1 73,178,917 73,226,504 RGD:8554872
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:11554173
Hydatidiform Mole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cga glycoprotein hormones, alpha polypeptide JBrowse link 5 50,362,491 50,393,368 RGD:2293636
G Khdc3 KH domain containing 3, subcortical maternal complex member JBrowse link 8 79,781,941 79,783,845 RGD:11554173
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:2293517
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:2290363
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:2293517
G Ncr1 natural cytotoxicity triggering receptor 1 JBrowse link 1 73,178,917 73,226,504 RGD:8554872
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:2292200
Hydatidiform Mole, Invasive term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:2293517
Hydatidiform Mole, Recurrent, 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Khdc3 KH domain containing 3, subcortical maternal complex member JBrowse link 8 79,781,941 79,783,845 RGD:7240710
RGD:8554872
Hydatidiform Mole, Recurrent, 3 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mei1 meiotic double-stranded break formation protein 1 JBrowse link 7 123,308,041 123,361,391 RGD:7240710
RGD:8554872
Hydatidiform Mole, Recurrent, 4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RGD1563323 similar to hypothetical protein FLJ22531 JBrowse link 1 219,864,108 219,952,143 RGD:7240710
RGD:8554872

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15603
    disease of cellular proliferation 5804
      Neoplastic Pregnancy Complications 17
        trophoblastic neoplasm 17
          choriocarcinoma + 6
          epithelioid trophoblastic tumor 0
          gestational trophoblastic neoplasm + 10
          testicular trophoblastic tumor 0
Path 2
Term Annotations click to browse term
  disease 15603
    disease of cellular proliferation 5804
      cancer 4121
        cell type cancer 2927
          sarcoma 227
            germ cell and embryonal cancer 41
              trophoblastic neoplasm 17
                choriocarcinoma + 6
                epithelioid trophoblastic tumor 0
                gestational trophoblastic neoplasm + 10
                testicular trophoblastic tumor 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.