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ONTOLOGY REPORT - ANNOTATIONS


Term:myelodysplastic/myeloproliferative neoplasm
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Accession:DOID:4972 term browser browse the term
Definition:Clonal myeloid disorders that possess both dysplastic and proliferative features but are not properly classified as either MYELODYSPLASTIC SYNDROMES or MYELOPROLIFERATIVE DISORDERS.
Synonyms:exact_synonym: MDS/MPN;   Myelodysplastic-Myeloproliferative Disease;   Myelodysplastic-Myeloproliferative Diseases;   Myeloproliferative Myelodisplastic Diseases;   Myeloproliferative-Myelodisplastic Disease;   Myeloproliferative/Myelodysplastic syndromes;   myelodysplastic myeloproliferative cancer;   myelodysplastic syndrome/myeloproliferative neoplasm
 primary_id: MESH:D054437;   RDO:0006889
 xref: NCI:C27262
For additional species annotation, visit the Alliance of Genome Resources.


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myelodysplastic/myeloproliferative neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddx41 DEAD-box helicase 41 JBrowse link 17 9,631,925 9,637,317 RGD:13592920
G Dido1 death inducer-obliterator 1 JBrowse link 3 176,162,886 176,216,868 RGD:13592920
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 4 77,284,404 77,347,011 RGD:11038772
RGD:11554173
atypical chronic myeloid leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:11352668
G Setbp1 SET binding protein 1 JBrowse link 18 75,090,733 75,432,446 RGD:11554173
chronic myelomonocytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asxl1 ASXL transcriptional regulator 1 JBrowse link 3 148,832,231 148,902,356 RGD:11038767
G Cdkn2b cyclin-dependent kinase inhibitor 2B JBrowse link 5 107,834,353 107,857,428 RGD:11252180
G Csf3r colony stimulating factor 3 receptor JBrowse link 5 144,031,353 144,051,966 RGD:10450469
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 4 77,284,404 77,347,011 RGD:10450882
G Kdm6a lysine demethylase 6A JBrowse link X 4,805,493 4,945,788 RGD:13592920
G Nras NRAS proto-oncogene, GTPase JBrowse link 2 205,553,119 205,563,716 RGD:11535058
G Tet2 tet methylcytosine dioxygenase 2 JBrowse link 2 238,719,389 238,802,975 RGD:11038679
juvenile myelomonocytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap12 A-kinase anchoring protein 12 JBrowse link 1 40,816,130 40,906,582 RGD:14348967
G Arhgap26 Rho GTPase activating protein 26 JBrowse link 18 31,807,052 32,557,176 RGD:7240710
RGD:8554872
G Asxl1 ASXL transcriptional regulator 1 JBrowse link 3 148,832,231 148,902,356 RGD:11554173
RGD:8554872
G Cbl Cbl proto-oncogene JBrowse link 8 48,481,256 48,564,775 RGD:11038806
RGD:7240710
RGD:8554872
RGD:11554173
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:10449526
RGD:11554173
G Dnmt3a DNA methyltransferase 3 alpha JBrowse link 6 28,205,375 28,346,052 RGD:11554173
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 4 77,284,404 77,347,011 RGD:11554173
G Flt3 fms-related tyrosine kinase 3 JBrowse link 12 9,360,439 9,437,004 RGD:13592920
G Gata2 GATA binding protein 2 JBrowse link 4 120,129,028 120,142,490 RGD:11554173
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:11069125
RGD:11554173
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:11554173
RGD:8554872
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:7240710
RGD:8554872
RGD:11554173
G Nras NRAS proto-oncogene, GTPase JBrowse link 2 205,553,119 205,563,716 RGD:11554173
RGD:8554872
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 12 40,895,515 40,955,999 RGD:7240710
RGD:8554872
RGD:11066398
RGD:11554173
G Rac2 Rac family small GTPase 2 JBrowse link 7 119,769,708 119,797,111 RGD:11554173
G Rras RAS related JBrowse link 1 101,012,822 101,016,720 RGD:11554173
G Rras2 RAS related 2 JBrowse link 1 178,940,515 179,010,257 RGD:11554173
G Runx1 RUNX family transcription factor 1 JBrowse link 11 32,765,147 33,003,061 RGD:11554173
G Setbp1 SET binding protein 1 JBrowse link 18 75,090,733 75,432,446 RGD:11554173
G Sh2b3 SH2B adaptor protein 3 JBrowse link 12 40,261,990 40,265,757 RGD:11554173
G Zrsr2 zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2 JBrowse link X 32,304,707 32,327,419 RGD:11554173
myeloproliferative disorder with eosinophilia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:7240710
Noonan Syndrome-Like Disorder with or without Juvenile Myelomonocytic Leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbl Cbl proto-oncogene JBrowse link 8 48,481,256 48,564,775 RGD:7240710
RGD:8554872
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 12 40,895,515 40,955,999 RGD:8554872

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15619
    disease of anatomical entity 14948
      hematopoietic system disease 1451
        bone marrow disease 402
          myelodysplastic/myeloproliferative neoplasm 29
            atypical chronic myeloid leukemia 2
            chronic myelomonocytic leukemia + 8
            juvenile myelomonocytic leukemia + 21
Path 2
Term Annotations click to browse term
  disease 15619
    disease of anatomical entity 14948
      Hemic and Lymphatic Diseases 1723
        hematopoietic system disease 1451
          bone marrow disease 402
            Bone Marrow Neoplasms 290
              bone marrow cancer 290
                myeloid neoplasm 229
                  myelodysplastic/myeloproliferative neoplasm 29
                    atypical chronic myeloid leukemia 2
                    chronic myelomonocytic leukemia + 8
                    juvenile myelomonocytic leukemia + 21
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.