ONTOLOGY REPORT - ANNOTATIONS


Term:central nervous system vasculitis
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Accession:DOID:525 term browser browse the term
Definition:Inflammation of blood vessels within the central nervous system. Primary vasculitis is usually caused by autoimmune or idiopathic factors, while secondary vasculitis is caused by existing disease process. Clinical manifestations are highly variable but include HEADACHE; SEIZURES; behavioral alterations; INTRACRANIAL HEMORRHAGES; TRANSIENT ISCHEMIC ATTACK; and BRAIN INFARCTION. (From Adams et al., Principles of Neurology, 6th ed, pp856-61)
Synonyms:exact_synonym: CNS Vasculitis;   Cerebral Vasculitis;   Granulomatous Arteritis;   central nervous system angiitis;   cerebral angiitis;   postzoster arteritis;   primary CNS vasculitis;   primary central nervous system vasculitis;   secondary CNS vasculitis
 primary_id: MESH:D020293
 alt_id: RDO:0000266
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Lupus Vasculitis, Central Nervous System term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr3a Fc fragment of IgG receptor IIIa JBrowse link 13 89,385,775 89,396,047 RGD:11554173
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:11554173
G Selp selectin P JBrowse link 13 82,428,914 82,464,629 RGD:6478687
temporal arteritis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:1581162
G Chi3l1 chitinase 3 like 1 JBrowse link 13 51,022,844 51,030,797 RGD:5024918
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:1581301
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:9491785
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:11059502
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:6482238
G Eln elastin JBrowse link 12 24,978,478 25,021,864 RGD:9585754
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:5147974
G Fcgr3a Fc fragment of IgG receptor IIIa JBrowse link 13 89,385,775 89,396,047 RGD:5147974
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:8157621
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:8698666
RGD:9068454
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:8655865
G Il21r interleukin 21 receptor JBrowse link 1 196,996,405 197,024,185 RGD:6892962
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:7829811
G Jag1 jagged canonical Notch ligand 1 JBrowse link 3 130,079,361 130,114,781 RGD:6482238
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:8693752
G Mfge8 milk fat globule-EGF factor 8 protein JBrowse link 1 140,845,478 140,860,882 RGD:1582497
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:8657040
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:1580575
RGD:8657040
RGD:8547902
RGD:8547826
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 JBrowse link 2 206,342,066 206,390,348 RGD:7829739
RGD:7829744
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:5147583
RGD:5147974
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:7777158
RGD:7777159

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14823
    disease of anatomical entity 13997
      nervous system disease 9111
        autoimmune disease of the nervous system 403
          central nervous system vasculitis 24
            AIDS Arteritis, Central Nervous System 0
            Familial Granulomatous Arteritis, with Juvenile Polyarthritis 0
            Lupus Vasculitis, Central Nervous System 3
            Primary Angiitis of the Central Nervous System 0
            cerebral arteritis 0
            granulomatous angiitis 0
            temporal arteritis + 22
Path 2
Term Annotations click to browse term
  disease 14823
    disease of anatomical entity 13997
      Immune & Inflammatory Diseases 3007
        immune system disease 2440
          hypersensitivity reaction disease 1488
            autoimmune hypersensitivity disease 1197
              autoimmune disease of the nervous system 403
                central nervous system vasculitis 24
                  AIDS Arteritis, Central Nervous System 0
                  Familial Granulomatous Arteritis, with Juvenile Polyarthritis 0
                  Lupus Vasculitis, Central Nervous System 3
                  Primary Angiitis of the Central Nervous System 0
                  cerebral arteritis 0
                  granulomatous angiitis 0
                  temporal arteritis + 22
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.