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Term:oxyphilic adenoma
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Accession:DOID:5389 term browser browse the term
Definition:A usually benign glandular tumor composed of oxyphil cells, large cells with small irregular nuclei and dense acidophilic granules due to the presence of abundant MITOCHONDRIA. Oxyphil cells, also known as oncocytes, are found in oncocytomas of the kidney, salivary glands, and endocrine glands. In the thyroid gland, oxyphil cells are known as Hurthle cells and Askanazy cells.
Synonyms:exact_synonym: Follicular adenoma, oxyphilic cell;   Huerthle Cell Tumor;   Hurthle Cell Tumor;   Oncocytoma
 primary_id: MESH:D018249;   RDO:0003645
 xref: NCI:C3759
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oxyphilic adenoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:2292414
G Krt7 keratin 7 JBrowse link 7 143,059,731 143,075,907 RGD:11554173
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 JBrowse link MT 13,543 14,061 RGD:8554872
G Pvalb parvalbumin JBrowse link 7 119,428,657 119,443,674 RGD:11554173
renal oncocytoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Flcn folliculin JBrowse link 10 46,153,185 46,172,331 RGD:11554173
thyroid gland Hurthle cell carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbx7 chromobox 7 JBrowse link 7 121,136,067 121,153,503 RGD:11352710
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 JBrowse link 16 21,275,311 21,282,246 RGD:7240710
G Psmb9 proteasome 20S subunit beta 9 JBrowse link 20 3,973,424 3,978,845 RGD:6483332

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  disease 16021
    disease of cellular proliferation 5889
      benign neoplasm 948
        organ system benign neoplasm 443
          endocrine organ benign neoplasm 138
            oxyphilic adenoma 8
              renal oncocytoma + 1
              thyroid gland Hurthle cell carcinoma 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.