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Accession:DOID:5394 term browser browse the term
Definition:A pituitary adenoma which secretes PROLACTIN, leading to HYPERPROLACTINEMIA. Clinical manifestations include AMENORRHEA; GALACTORRHEA; IMPOTENCE; HEADACHE; visual disturbances; and CEREBROSPINAL FLUID RHINORRHEA.
Synonyms:exact_synonym: Lactotroph Adenomas;   Macroprolactinoma;   Macroprolactinomas;   Microprolactinoma;   Microprolactinomas;   PRL Secreting Pituitary Adenoma;   PRL-Secreting Pituitary Adenomas;   Prolactin Producing Pituitary Adenoma;   Prolactin-Producing Pituitary Adenomas;   Prolactinoma, Familial;   Prolactinomas;   lactotroph adenoma;   prolactin secreting pituitary adenoma;   prolactinoma of pituitary gland
 primary_id: MESH:D015175
 alt_id: OMIM:600634;   RDO:0006849
 xref: GARD:4508;   NCI:C3342
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prolactinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aip aryl-hydrocarbon receptor-interacting protein JBrowse link 1 219,361,859 219,373,924 RGD:8554872
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:629544
G Cebpd CCAAT/enhancer binding protein delta JBrowse link 11 89,008,008 89,009,146 RGD:11554173
G Hpgd 15-hydroxyprostaglandin dehydrogenase JBrowse link 16 37,457,134 37,495,758 RGD:11667097
G Lrp2 LDL receptor related protein 2 JBrowse link 3 55,665,153 55,822,484 RGD:8554872
G Men1 menin 1 JBrowse link 1 221,704,394 221,710,343 RGD:13592920
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:7240531
G Nog noggin JBrowse link 10 76,811,759 76,813,386 RGD:629544
G Npy5r neuropeptide Y receptor Y5 JBrowse link 16 24,796,685 24,805,730 RGD:1625506
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:1642576
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:11667097

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15626
    disease of anatomical entity 14956
      endocrine system disease 4803
        pituitary gland disease 154
          pituitary gland benign neoplasm 22
            pituitary adenoma 22
              prolactinoma 11
Path 2
Term Annotations click to browse term
  disease 0
    disease of cellular proliferation 5797
      cancer 4113
        organ system cancer 3924
          nervous system cancer 1708
            central nervous system cancer 956
              brain cancer 940
                supratentorial cancer 851
                  diencephalic neoplasm 70
                    thalamic neoplasm 70
                      hypothalamic neoplasm 70
                        Pituitary Neoplasms 68
                          pituitary adenoma 22
                            functioning pituitary adenoma 20
                              prolactinoma 11
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.