Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:synovial sarcoma
go back to main search page
Accession:DOID:5485 term browser browse the term
Definition:A malignant neoplasm arising from tenosynovial tissue of the joints and in synovial cells of tendons and bursae. The legs are the most common site, but the tumor can occur in the abdominal wall and other trunk muscles. There are two recognized types: the monophasic (characterized by sheaths of monotonous spindle cells) and the biphasic (characterized by slit-like spaces or clefts within the tumor, lined by cuboidal or tall columnar epithelial cells). These sarcomas occur most commonly in the second and fourth decades of life. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1363)
Synonyms:exact_synonym: Synovial Sarcomas;   Synovioma;   Synoviomas
 primary_id: MESH:D013584;   RDO:0006659
 alt_id: OMIM:300813
 xref: GARD:7721;   NCI:C3400
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
synovial sarcoma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator ISO CTD Direct Evidence: therapeutic CTD PMID:16450387 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Shcbp1 SHC binding and spindle associated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27572315 NCBI chr16:90,613,826...90,642,683
Ensembl chr16:90,613,870...90,641,420
JBrowse link
G Ss18 SS18 subunit of BAF chromatin remodeling complex ISO CTD Direct Evidence: marker/mechanism CTD PMID:9428816, PMID:27572315, PMID:7951320 RGD:1599184 NCBI chr18:6,020,267...6,083,055
Ensembl chr18:6,020,267...6,083,033
JBrowse link
G Ssx1 SSX family member 1 ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
PMID:9428816, PMID:27572315 NCBI chr  X:14,903,854...14,911,999
Ensembl chr  X:14,905,337...14,910,778
JBrowse link
G Vim vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15043115 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16045
    disease of cellular proliferation 5917
      cancer 4242
        cell type cancer 3110
          sarcoma 237
            synovial sarcoma 5
              biphasic synovial sarcoma 0
              epithelioid cell synovial sarcoma 0
              fibrous synovial sarcoma 0
              mediastinum synovial sarcoma 0
              monophasic synovial sarcoma 0
              spindle cell synovial sarcoma 0
Path 2
Term Annotations click to browse term
  disease 16045
    disease of cellular proliferation 5917
      Neoplasms by Histologic Type 3728
        Connective and Soft Tissue Neoplasms 1510
          Connective Tissue Neoplasms 1391
            connective tissue cancer 1262
              synovium cancer 5
                synovial sarcoma 5
                  biphasic synovial sarcoma 0
                  epithelioid cell synovial sarcoma 0
                  fibrous synovial sarcoma 0
                  mediastinum synovial sarcoma 0
                  monophasic synovial sarcoma 0
                  spindle cell synovial sarcoma 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.