Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:myocardial infarction
go back to main search page
Accession:DOID:5844 term browser browse the term
Definition:NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
Synonyms:exact_synonym: Cardiovascular Stroke;   Cardiovascular Strokes;   Heart Attacks;   MCI2;   MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO;   MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO, 2;   Myocardial Infarct;   Myocardial Infarctions;   Myocardial Infarcts;   heart attack
 narrow_synonym: MCI1;   MYOCARDIAL INFARCTION, PROTECTION AGAINST;   MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO, 1
 related_synonym: MYOCARDIAL INFARCTION, DECREASED SUSCEPTIBILITY TO
 primary_id: MESH:D009203;   RDO:0006167
 alt_id: OMIM:608446;   OMIM:608557
 xref: ICD10CM:I22;   NCI:C27996
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants       view all columns           Sort by:
 
myocardial infarction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc9 ATP binding cassette subfamily C member 9 JBrowse link 4 176,806,098 176,928,540 RGD:8554872
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:1331525
RGD:8554872
RGD:11554173
RGD:9685449
RGD:1558664
RGD:7829785
RGD:6893480
G Ace2 angiotensin I converting enzyme 2 JBrowse link X 32,050,734 32,095,860 RGD:1558664
RGD:9685449
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:11554173
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 JBrowse link 11 25,342,119 25,350,938 RGD:9681751
G Add1 adducin 1 JBrowse link 14 81,367,466 81,426,610 RGD:5147995
RGD:5148001
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:5686351
G Adipor1 adiponectin receptor 1 JBrowse link 13 51,240,470 51,260,233 RGD:1625764
G Adipor2 adiponectin receptor 2 JBrowse link 4 151,412,135 151,480,108 RGD:1625764
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:11554173
G Adora3 adenosine A3 receptor JBrowse link 2 208,336,909 208,379,217 RGD:11554173
G Adra2b adrenoceptor alpha 2B JBrowse link 3 119,805,941 119,809,987 RGD:1559314
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:1331525
RGD:7241557
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:1601126
RGD:8548519
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:2325647
RGD:1625333
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:5129191
RGD:11554173
RGD:1331525
RGD:1566452
RGD:1601132
G Agtr1a angiotensin II receptor, type 1a JBrowse link 17 35,907,102 35,958,136 RGD:1601150
RGD:10047101
RGD:1331525
RGD:1566499
G Ahsg alpha-2-HS-glycoprotein JBrowse link 11 81,711,269 81,717,594 RGD:2313810
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 JBrowse link 2 237,727,782 237,751,327 RGD:1580021
G Ak1 adenylate kinase 1 JBrowse link 3 11,652,143 11,659,135 RGD:11100025
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:5509094
RGD:10041035
G Aldh2 aldehyde dehydrogenase 2 family member JBrowse link 12 40,466,418 40,498,813 RGD:2311152
G Alox5ap arachidonate 5-lipoxygenase activating protein JBrowse link 12 6,854,930 6,879,112 RGD:1578317
RGD:1331525
RGD:2313891
G Ang angiogenin JBrowse link 15 28,022,926 28,028,636 RGD:2325719
G Angpt1 angiopoietin 1 JBrowse link 7 81,338,327 81,592,459 RGD:1626168
G Angpt2 angiopoietin 2 JBrowse link 16 75,966,480 76,016,147 RGD:1601493
G Anxa5 annexin A5 JBrowse link 2 123,162,477 123,194,730 RGD:2317542
RGD:2317541
RGD:2317543
RGD:1578384
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:2325759
RGD:1331525
RGD:1578442
G Apoa4 apolipoprotein A4 JBrowse link 8 50,536,983 50,539,371 RGD:1578442
RGD:5685678
RGD:1331525
G Apob apolipoprotein B JBrowse link 6 33,176,826 33,216,381 RGD:1331525
G Apoc3 apolipoprotein C3 JBrowse link 8 50,529,318 50,531,498 RGD:1578442
RGD:1331525
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1601229
RGD:11554173
RGD:10449412
RGD:8554872
RGD:1331525
G Apoh apolipoprotein H JBrowse link 10 96,640,013 96,653,939 RGD:2313985
RGD:10054111
G Atg7 autophagy related 7 JBrowse link 4 146,570,113 146,777,093 RGD:11557988
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:10053570
RGD:11554173
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 JBrowse link 2 204,003,742 204,032,023 RGD:11554173
G Atp5f1d ATP synthase F1 subunit delta JBrowse link 7 12,426,807 12,432,120 RGD:13792656
RGD:13792681
G Atp5po ATP synthase peripheral stalk subunit OSCP JBrowse link 11 32,081,606 32,087,918 RGD:13801194
G Avpr1a arginine vasopressin receptor 1A JBrowse link 7 67,341,366 67,345,290 RGD:2300376
G Bak1 BCL2-antagonist/killer 1 JBrowse link 20 5,609,620 5,618,899 RGD:11554173
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:11554173
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:11554173
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:1643494
RGD:11554173
G Bdkrb1 bradykinin receptor B1 JBrowse link 6 129,437,423 129,441,553 RGD:704379
G Bdkrb2 bradykinin receptor B2 JBrowse link 6 129,399,468 129,429,676 RGD:704379
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:11554173
RGD:11561913
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:2293137
G Bnip3 BCL2 interacting protein 3 JBrowse link 1 211,248,098 211,265,282 RGD:11557988
G Brap BRCA1 associated protein JBrowse link 12 40,381,892 40,417,764 RGD:11554173
G Brinp3 BMP/retinoic acid inducible neural specific 3 JBrowse link 13 63,526,486 63,959,390 RGD:14398488
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:1600605
G C7 complement C7 JBrowse link 2 54,707,621 54,781,624 RGD:1599522
G C8a complement C8 alpha chain JBrowse link 5 124,348,536 124,403,117 RGD:1600501
G C8b complement C8 beta chain JBrowse link 5 124,298,269 124,338,055 RGD:1600501
G Cacybp calcyclin binding protein JBrowse link 13 77,948,771 77,959,089 RGD:2326117
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:2315913
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:11554173
RGD:13782309
G Casr calcium-sensing receptor JBrowse link 11 67,188,204 67,262,261 RGD:7205672
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:1581148
RGD:11554173
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:1599542
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:2307033
RGD:8549616
RGD:1581161
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:4890013
G Ccn2 cellular communication network factor 2 JBrowse link 1 21,851,657 21,854,773 RGD:2314623
G Ccna2 cyclin A2 JBrowse link 2 123,274,727 123,282,266 RGD:10054471
G Ccr2 C-C motif chemokine receptor 2 RGD:1581177
RGD:1581174
G Ccr3 C-C motif chemokine receptor 3 JBrowse link 8 133,026,539 133,040,999 RGD:4890013
G Cct7 chaperonin containing TCP1 subunit 7 JBrowse link 4 117,235,023 117,252,265 RGD:8554872
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:1580252
RGD:1580255
RGD:2314155
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6893560
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:2314209
G Cd59 CD59 molecule JBrowse link 3 94,010,481 94,028,660 RGD:1600501
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:10045366
G Cfl1 cofilin 1 JBrowse link 1 220,869,805 220,873,337 RGD:11570534
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:11566046
G Chi3l1 chitinase 3 like 1 JBrowse link 13 51,022,844 51,030,797 RGD:4892633
G Ciita class II, major histocompatibility complex, transactivator JBrowse link 10 5,212,621 5,260,641 RGD:1358146
RGD:5491201
G Ckb creatine kinase B JBrowse link 6 136,142,956 136,145,838 RGD:11554173
G Ckm creatine kinase, M-type JBrowse link 1 80,321,507 80,331,841 RGD:11554173
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:9068409
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:11041598
G Col3a1 collagen type III alpha 1 chain JBrowse link 9 52,023,295 52,059,221 RGD:11041598
G Col4a1 collagen type IV alpha 1 chain JBrowse link 16 83,522,162 83,632,153 RGD:2311341
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:11554173
G Crem cAMP responsive element modulator JBrowse link 17 57,021,704 57,090,888 RGD:11554173
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:5131456
RGD:9491780
RGD:6482304
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:5131507
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:11039417
G Csnk2a1 casein kinase 2 alpha 1 JBrowse link 3 147,713,808 147,760,375 RGD:11565830
G Csnk2b casein kinase 2 beta JBrowse link 20 5,108,692 5,113,675 RGD:11565830
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:2301976
G Ctsb cathepsin B JBrowse link 15 46,316,741 46,337,613 RGD:2315501
G Cxcl12 C-X-C motif chemokine ligand 12 JBrowse link 4 149,261,044 149,273,891 RGD:632503
RGD:2306567
G Cyba cytochrome b-245 alpha chain JBrowse link 19 55,249,634 55,257,824 RGD:2317860
RGD:1599690
G Cybb cytochrome b-245 beta chain JBrowse link X 14,578,330 14,610,049 RGD:1599690
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 JBrowse link 7 116,248,759 116,255,205 RGD:2307303
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 JBrowse link 5 119,546,458 119,564,843 RGD:1625380
G Dab2 DAB adaptor protein 2 JBrowse link 2 55,747,353 55,768,848 RGD:7243156
RGD:7243158
G Dab2ip DAB2 interacting protein JBrowse link 3 14,889,263 15,060,286 RGD:11554173
G Dag1 dystroglycan 1 JBrowse link 8 116,980,501 116,993,182 RGD:11541047
G Dcn decorin JBrowse link 7 38,742,250 38,782,282 RGD:1598497
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:11554173
G Dgkz diacylglycerol kinase zeta JBrowse link 3 80,844,002 80,886,487 RGD:11554173
G Dvl1 dishevelled segment polarity protein 1 JBrowse link 5 173,295,948 173,308,014 RGD:1580899
G Ece1 endothelin converting enzyme 1 JBrowse link 5 156,215,469 156,318,652 RGD:1580912
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:4144880
RGD:1580921
G Edn2 endothelin 2 JBrowse link 5 139,098,472 139,106,396 RGD:1580921
G Ednra endothelin receptor type A JBrowse link 19 33,928,356 33,991,703 RGD:1580948
G Ednrb endothelin receptor type B JBrowse link 15 88,004,775 88,036,354 RGD:1580948
G Egln1 egl-9 family hypoxia-inducible factor 1 JBrowse link 19 57,660,194 57,701,158 RGD:11252084
G Egln3 egl-9 family hypoxia-inducible factor 3 JBrowse link 6 75,050,329 75,075,795 RGD:11252084
G Epas1 endothelial PAS domain protein 1 JBrowse link 6 10,306,508 10,385,239 RGD:1580977
RGD:5147886
G Ephx2 epoxide hydrolase 2 JBrowse link 15 42,757,241 42,794,211 RGD:5688358
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:10400907
RGD:11554173
G Epor erythropoietin receptor JBrowse link 8 22,969,737 22,974,468 RGD:10400907
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1331525
RGD:7240710
RGD:11554173
RGD:8554872
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:8554872
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:11041803
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:1581022
RGD:7240710
RGD:8554872
RGD:11554173
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:11554173
RGD:1581022
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:11062083
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:11554173
RGD:11564337
RGD:11564335
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:2312409
RGD:11554173
RGD:7240710
RGD:8554872
RGD:11049521
RGD:1580374
G Fabp3 fatty acid binding protein 3 JBrowse link 5 148,528,854 148,535,597 RGD:1582401
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:1331525
RGD:1580381
G Fgf1 fibroblast growth factor 1 JBrowse link 18 32,273,830 32,359,831 RGD:10449026
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:10402087
G Fis1 fission, mitochondrial 1 JBrowse link 12 22,750,485 22,765,324 RGD:11557988
G Flt1 Fms related receptor tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:1601493
G Flt3lg Fms related receptor tyrosine kinase 3 ligand JBrowse link 1 101,126,006 101,131,413 RGD:11049498
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:2325720
G Fzd2 frizzled class receptor 2 JBrowse link 10 90,550,147 90,552,057 RGD:4107058
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:10449173
G Gata4 GATA binding protein 4 JBrowse link 15 46,386,703 46,458,679 RGD:7327215
RGD:11554173
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:1302515
RGD:7240710
RGD:11554173
RGD:8554872
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:8554872
RGD:7240710
RGD:11554173
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 20 14,019,723 14,045,781 RGD:11554173
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:11352745
G Ghrh growth hormone releasing hormone JBrowse link 3 153,449,124 153,468,794 RGD:10401242
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:7207261
RGD:13592597
RGD:7207262
G Gja4 gap junction protein, alpha 4 JBrowse link 5 145,374,688 145,377,221 RGD:1580400
G Gja5 gap junction protein, alpha 5 JBrowse link 2 199,162,745 199,184,942 RGD:13592597
G Gp1ba glycoprotein Ib platelet subunit alpha JBrowse link 10 57,260,680 57,263,546 RGD:1580432
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:1600662
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:10045368
RGD:11554173
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:10401898
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 JBrowse link 2 181,045,694 181,103,321 RGD:8554872
G Hadh hydroxyacyl-CoA dehydrogenase JBrowse link 2 236,353,445 236,395,067 RGD:2302229
G Hamp hepcidin antimicrobial peptide JBrowse link 1 89,368,021 89,369,960 RGD:11041636
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:1582672
RGD:1582697
G Hgf hepatocyte growth factor JBrowse link 4 15,435,460 15,505,377 RGD:8548609
RGD:8548632
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:5147886
RGD:1580977
RGD:9068466
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:10402174
RGD:11554173
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:1598393
RGD:4145134
G Hp haptoglobin JBrowse link 19 42,096,255 42,100,805 RGD:1626360
RGD:11554173
RGD:1626354
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 JBrowse link 19 37,476,083 37,481,326 RGD:2308939
RGD:11554173
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:11554173
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:1624230
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:8547733
RGD:11554173
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:2306696
RGD:1598421
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:10046050
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:1598480
RGD:11554173
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:9095344
G Il18bp interleukin 18 binding protein JBrowse link 1 167,091,521 167,095,727 RGD:4889400
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:7175553
RGD:11554173
RGD:7204425
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:11554173
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:4889985
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:11554173
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:1625444
G Itga2 integrin subunit alpha 2 JBrowse link 2 46,996,904 47,097,011 RGD:1582296
RGD:1581029
RGD:1582294
G Itga3 integrin subunit alpha 3 JBrowse link 10 82,855,841 82,887,755 RGD:2325287
G Itgb1 integrin subunit beta 1 JBrowse link 19 61,677,512 61,725,537 RGD:13602094
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:5128498
RGD:7240710
RGD:8554872
RGD:11554173
RGD:5128476
RGD:5128481
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 JBrowse link 16 6,970,367 6,985,538 RGD:1582334
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:10403083
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 JBrowse link 10 99,429,337 99,442,520 RGD:7247426
G Kcnk2 potassium two pore domain channel subfamily K member 2 JBrowse link 13 107,690,111 107,886,476 RGD:9831182
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:1581717
G Kif6 kinesin family member 6 JBrowse link 9 13,016,973 13,311,971 RGD:11554173
G Klf13 Kruppel-like factor 13 JBrowse link 1 124,772,596 124,803,363 RGD:11554173
G Klk1 kallikrein 1 JBrowse link 1 100,131,562 100,135,556 RGD:11554173
G Klk1c12 kallikrein 1-related peptidase C12 JBrowse link 1 99,298,965 99,303,048 RGD:1641799
G Lamp2 lysosomal-associated membrane protein 2 JBrowse link X 124,722,628 124,766,079 RGD:11557988
G Lcat lecithin cholesterol acyltransferase JBrowse link 19 37,913,333 37,916,799 RGD:1581773
G Ldha lactate dehydrogenase A JBrowse link 1 102,900,288 102,909,713 RGD:11554173
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:1331525
G Lgals2 galectin 2 JBrowse link 7 120,071,122 120,077,612 RGD:1581852
RGD:7240710
RGD:11554173
RGD:8554872
G Lgals3 galectin 3 JBrowse link 15 24,153,602 24,165,537 RGD:11554173
G Lipg lipase G, endothelial type JBrowse link 18 70,903,528 70,924,434 RGD:1641818
G Lox lysyl oxidase JBrowse link 18 47,500,320 47,577,819 RGD:1581883
G Lpl lipoprotein lipase JBrowse link 16 22,537,687 22,561,487 RGD:2313302
G Lrp1 LDL receptor related protein 1 JBrowse link 7 70,846,313 70,927,028 RGD:1581913
G Lrp8 LDL receptor related protein 8 JBrowse link 5 127,404,348 127,476,636 RGD:2306125
RGD:11554173
RGD:7240710
RGD:8554872
RGD:2306124
G Lrpap1 LDL receptor related protein associated protein 1 JBrowse link 14 80,911,281 80,923,290 RGD:1581922
G Lta lymphotoxin alpha JBrowse link 20 4,851,889 4,854,677 RGD:1581940
RGD:7240710
RGD:11554173
RGD:8554872
RGD:8548841
RGD:1580417
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha JBrowse link 3 150,801,289 150,802,935 RGD:11561913
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 15,412,603 15,613,752 RGD:10412335
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:1582282
G Mdh2 malate dehydrogenase 2 JBrowse link 12 23,941,451 23,954,406 RGD:1582468
G Mdk midkine JBrowse link 3 80,841,003 80,843,895 RGD:1582488
G Mef2a myocyte enhancer factor 2a JBrowse link 1 128,207,715 128,341,681 RGD:1580548
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:7327215
G Mff mitochondrial fission factor JBrowse link 9 88,490,280 88,518,517 RGD:12879458
RGD:11554173
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:12738232
G Mgp matrix Gla protein JBrowse link 4 170,856,783 170,860,105 RGD:1582503
G Mia3 MIA SH3 domain ER export factor 3 JBrowse link 13 101,727,434 101,770,127 RGD:11554173
G Miat myocardial infarction associated transcript JBrowse link 12 50,447,251 50,461,859 RGD:8554872
RGD:7240710
RGD:11554173
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:1642008
RGD:1642003
G Mir125b2 microRNA 125b-2 JBrowse link 11 16,097,346 16,097,433 RGD:11554173
G Mir145 microRNA 145 JBrowse link 18 56,969,907 56,969,994 RGD:11554173
G Mir423 microRNA 423 JBrowse link 10 63,098,366 63,098,444 RGD:11554173
G Mir761 microRNA 761 JBrowse link 5 128,651,867 128,651,942 RGD:11554173
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:1582535
RGD:7207198
RGD:7207136
RGD:7207135
RGD:1582520
G Mmp13 matrix metallopeptidase 13 JBrowse link 8 5,522,739 5,533,018 RGD:1582556
G Mmp14 matrix metallopeptidase 14 JBrowse link 15 33,074,441 33,083,666 RGD:1582587
RGD:1582569
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:1582587
RGD:11554173
RGD:7207136
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:1580551
G Mmp7 matrix metallopeptidase 7 JBrowse link 8 5,893,253 5,900,965 RGD:1582373
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:1582645
RGD:13204799
RGD:11554173
RGD:7207198
RGD:7207049
RGD:1582653
RGD:1582639
G Mt-nd2 mitochondrially encoded NADH dehydrogenase 2 JBrowse link MT 3,904 4,942 RGD:1581054
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:6893548
RGD:10449412
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:10041035
RGD:10041040
G Myh6 myosin heavy chain 6 JBrowse link 15 33,605,653 33,629,730 RGD:11565830
G Myh7 myosin heavy chain 7 JBrowse link 15 33,605,769 33,657,761 RGD:11554173
RGD:11565830
G Ncam1 neural cell adhesion molecule 1 JBrowse link 8 53,836,797 54,134,881 RGD:2325979
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 JBrowse link 2 119,139,717 119,153,753 RGD:13801194
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:10412734
RGD:10412738
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:10413879
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:11554173
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:5128481
RGD:13503346
RGD:13450930
RGD:11554173
RGD:7771563
RGD:7771561
RGD:1580284
RGD:1580283
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:11535018
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:1579982
RGD:11554173
RGD:1580000
G Nppb natriuretic peptide B JBrowse link 5 164,796,176 164,797,538 RGD:2324680
RGD:7247724
RGD:1642266
G Npr1 natriuretic peptide receptor 1 JBrowse link 2 189,840,403 189,857,032 RGD:1580174
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 JBrowse link 19 34,408,275 34,761,003 RGD:11554173
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:10449026
G Nrip1 nuclear receptor interacting protein 1 JBrowse link 11 14,658,225 14,742,478 RGD:11554173
G Olr1 oxidized low density lipoprotein receptor 1 JBrowse link 4 163,239,853 163,261,937 RGD:1580996
RGD:7240710
RGD:11554173
RGD:8554872
G Opa1 OPA1, mitochondrial dynamin like GTPase JBrowse link 11 74,717,600 74,793,902 RGD:12738232
G Oprd1 opioid receptor, delta 1 JBrowse link 5 150,288,126 150,323,063 RGD:2316587
RGD:9831425
G Oprk1 opioid receptor, kappa 1 JBrowse link 5 13,742,655 13,760,460 RGD:9831425
G P2ry12 purinergic receptor P2Y12 JBrowse link 2 149,440,807 149,482,592 RGD:11554173
G Pappa1 pappalysin 1 JBrowse link 5 80,919,932 81,153,904 RGD:1642324
RGD:11554173
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:5684012
G Pcsk2 proprotein convertase subtilisin/kexin type 2 JBrowse link 3 137,618,891 137,923,385 RGD:6483554
G Pde3a phosphodiesterase 3A JBrowse link 4 175,431,904 175,703,844 RGD:11554173
G Pde5a phosphodiesterase 5A JBrowse link 2 226,899,604 227,044,916 RGD:2314468
G Pdgfd platelet derived growth factor D JBrowse link 8 4,441,010 4,666,754 RGD:9854703
G Pebp1 phosphatidylethanolamine binding protein 1 JBrowse link 12 45,026,948 45,031,148 RGD:2302667
G Pecam1 platelet and endothelial cell adhesion molecule 1 JBrowse link 10 94,850,971 94,913,202 RGD:2311656
RGD:6771224
RGD:1581009
G Pgf placental growth factor JBrowse link 6 108,994,016 109,004,598 RGD:6483584
RGD:6483777
RGD:6483773
G Phactr1 phosphatase and actin regulator 1 JBrowse link 17 23,245,423 23,761,207 RGD:11554173
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma JBrowse link 6 51,465,696 51,501,234 RGD:6482688
G Pla2g7 phospholipase A2 group VII JBrowse link 9 19,935,754 19,978,013 RGD:6482786
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:1580881
RGD:11554173
RGD:11541077
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:6484126
RGD:11554173
RGD:6484145
RGD:6484133
G Plaur plasminogen activator, urokinase receptor JBrowse link 1 81,328,171 81,344,954 RGD:1580897
RGD:6484133
G Plcb1 phospholipase C beta 1 JBrowse link 3 127,721,244 128,419,565 RGD:2314514
G Plcb3 phospholipase C beta 3 JBrowse link 1 222,207,887 222,224,993 RGD:2314514
G Pln phospholamban JBrowse link 20 34,633,157 34,642,904 RGD:7327176
RGD:11554173
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:1580202
RGD:1580198
G Postn periostin JBrowse link 2 143,656,820 143,688,087 RGD:10041024
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:5562819
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:7242181
RGD:11554173
RGD:6484266
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:11554173
G Proc protein C, inactivator of coagulation factors Va and VIIIa JBrowse link 18 24,918,402 24,928,822 RGD:11100014
G Psma6 proteasome 20S subunit alpha 6 JBrowse link 6 76,174,460 76,205,429 RGD:8554872
RGD:7240710
RGD:11554173
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1581289
G Ptn pleiotrophin JBrowse link 4 64,239,156 64,330,996 RGD:10044023
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:9831390
G Ranbp1 RAN binding protein 1 JBrowse link 11 86,890,585 86,898,818 RGD:9835001
G Reg1a regenerating family member 1 alpha JBrowse link 4 109,497,962 109,500,626 RGD:9850130
G Ren renin JBrowse link 13 50,502,724 50,513,953 RGD:6892687
RGD:11554173
G Retn resistin JBrowse link 12 2,201,909 2,203,649 RGD:7207152
G Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link 10 73,824,200 73,865,503 RGD:1642998
G S100b S100 calcium binding protein B JBrowse link 20 13,130,633 13,142,856 RGD:2325647
RGD:11554173
G Sdc1 syndecan 1 JBrowse link 6 33,885,576 33,908,038 RGD:2311712
G Sdc4 syndecan 4 JBrowse link 3 160,872,503 160,891,190 RGD:2312328
G Sell selectin L JBrowse link 13 82,369,820 82,387,774 RGD:11554173
G Selp selectin P JBrowse link 13 82,428,914 82,464,629 RGD:2312304
RGD:6219003
RGD:6218991
RGD:1580075
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:1626626
RGD:8547882
G Sfrp2 secreted frizzled-related protein 2 JBrowse link 2 182,723,732 182,731,277 RGD:4107088
G Sh2b3 SH2B adaptor protein 3 JBrowse link 12 40,261,990 40,265,757 RGD:11554173
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:12879408
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:2316169
G Sirt3 sirtuin 3 JBrowse link 1 213,613,502 213,636,061 RGD:9586050
G Slc27a1 solute carrier family 27 member 1 JBrowse link 16 19,997,823 20,016,193 RGD:1642800
G Slc27a6 solute carrier family 27 member 6 JBrowse link 18 53,609,497 53,667,833 RGD:1642800
G Slpi secretory leukocyte peptidase inhibitor JBrowse link 3 160,799,979 160,802,228 RGD:9999400
G Smad2 SMAD family member 2 JBrowse link 18 72,550,107 72,612,078 RGD:12903276
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:12903276
G Socs1 suppressor of cytokine signaling 1 JBrowse link 10 4,956,795 4,958,472 RGD:2298918
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:1581222
RGD:11554173
RGD:8655953
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:1581148
RGD:11554173
RGD:1580839
G Sod3 superoxide dismutase 3 JBrowse link 14 60,958,583 60,971,143 RGD:1580841
G Sparc secreted protein acidic and cysteine rich JBrowse link 10 40,742,390 40,764,232 RGD:2300056
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:1581386
RGD:1581325
G Tbx3 T-box transcription factor 3 JBrowse link 12 42,479,518 42,494,588 RGD:5132891
G Tbx5 T-box transcription factor 5 JBrowse link 12 42,059,688 42,148,226 RGD:7327215
G Tek TEK receptor tyrosine kinase JBrowse link 5 113,725,717 113,852,799 RGD:1601493
G Tfpi tissue factor pathway inhibitor JBrowse link 3 71,852,738 71,902,127 RGD:11060131
RGD:11062083
RGD:11060139
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1601560
RGD:11554173
RGD:11073666
RGD:1331525
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:2302107
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:1601617
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1601617
G Th tyrosine hydroxylase JBrowse link 1 216,073,034 216,080,287 RGD:1580048
G Thbd thrombomodulin JBrowse link 3 142,748,673 142,752,325 RGD:11554173
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:2317960
G Timp2 TIMP metallopeptidase inhibitor 2 JBrowse link 10 107,338,465 107,386,072 RGD:11554173
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1580734
RGD:5562819
G Tm6sf2 transmembrane 6 superfamily member 2 JBrowse link 16 21,092,483 21,099,695 RGD:11554173
G Tnc tenascin C JBrowse link 5 79,789,686 79,874,555 RGD:4889618
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:5130892
RGD:11554173
G Tnfrsf11b TNF receptor superfamily member 11B JBrowse link 7 93,798,580 93,826,586 RGD:1620893
G Tnfrsf12a TNF receptor superfamily member 12A JBrowse link 10 12,995,904 12,997,930 RGD:11554173
G Tnfrsf14 TNF receptor superfamily member 14 JBrowse link 5 172,328,259 172,337,221 RGD:2317281
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link 4 157,864,905 157,877,634 RGD:5130892
RGD:5130975
RGD:1624194
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link 5 163,136,390 163,167,299 RGD:5130892
G Tnfsf11 TNF superfamily member 11 JBrowse link 15 60,482,527 60,512,704 RGD:2302363
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1580396
RGD:11554173
RGD:7240710
G Tnni3 troponin I3, cardiac type JBrowse link 1 72,882,806 72,886,490 RGD:11554173
G Tnnt2 troponin T2, cardiac type JBrowse link 13 52,662,974 52,680,992 RGD:1580441
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:11554173
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:13792689
G Trpv1em1Sage transient receptor potential cation channel, subfamily V, member 1; ZFN induced mutant 1, Sage RGD:13792689
G Ttn titin JBrowse link 3 63,565,160 63,837,815 RGD:1580780
G Txn1 thioredoxin 1 JBrowse link 5 75,049,735 75,057,731 RGD:1580785
G Txnrd1 thioredoxin reductase 1 JBrowse link 7 26,946,124 26,984,400 RGD:5134341
G Uts2 urotensin 2 JBrowse link 5 168,078,748 168,084,133 RGD:2306846
G Uts2r urotensin 2 receptor JBrowse link 10 110,364,291 110,365,451 RGD:2306846
G Vcan versican JBrowse link 2 18,490,102 18,587,340 RGD:1598497
G Vdac1 voltage-dependent anion channel 1 JBrowse link 10 37,724,915 37,752,827 RGD:11554173
G Vdac2 voltage-dependent anion channel 2 JBrowse link 15 2,634,622 2,648,548 RGD:10003049
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:7483604
G Vegfb vascular endothelial growth factor B JBrowse link 1 222,237,000 222,242,786 RGD:2314324
G Vwf von Willebrand factor JBrowse link 4 158,085,059 158,219,525 RGD:11080745
G Wdr12 WD repeat domain 12 JBrowse link 9 66,851,499 66,878,534 RGD:11554173
G Wfdc6a WAP four-disulfide core domain 6A JBrowse link 3 161,036,703 161,040,511 RGD:11554173
G Wrn WRN RecQ like helicase JBrowse link 16 62,483,773 62,619,018 RGD:1580821
G Ybx1 Y box binding protein 1 JBrowse link 5 138,319,754 138,336,721 RGD:1580630
acute myocardial infarction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:11552746
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 JBrowse link 10 95,954,160 96,015,484 RGD:13524557
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:13782284
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:13782284
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:13792778
G Serping1 serpin family G member 1 JBrowse link 3 72,161,230 72,171,109 RGD:11552746
anterolateral myocardial infarction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:8661757
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:13208541
Cardiogenic Shock term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:11554173
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:11554173
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:11554173
Coronary Artery Disease, Autosomal Dominant 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mef2a myocyte enhancer factor 2a JBrowse link 1 128,207,715 128,341,681 RGD:7240710
RGD:8554872
Coronary Artery Disease, Autosomal Dominant 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:7240710
RGD:8554872
myocardial stunning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 12 39,553,903 39,603,326 RGD:11554173
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:11554173
G Pln phospholamban JBrowse link 20 34,633,157 34,642,904 RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173
No-Reflow Phenomenon term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdh5 cadherin 5 JBrowse link 19 1,025,122 1,074,333 RGD:11554173
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:11554173
G Jup junction plakoglobin JBrowse link 10 88,280,517 88,307,451 RGD:11554173
ST Elevation Myocardial Infarction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:14700903
G Atp5mc2 ATP synthase membrane subunit c locus 2 JBrowse link 7 144,264,207 144,272,578 RGD:14696800
G Lgals3 galectin 3 JBrowse link 15 24,153,602 24,165,537 RGD:11554173

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15553
    disease of anatomical entity 14837
      cardiovascular system disease 4218
        vascular disease 3250
          Myocardial Ischemia 805
            myocardial infarction 350
              Cardiogenic Shock 3
              Coronary Artery Disease, Autosomal Dominant 1 1
              Coronary Artery Disease, Autosomal Dominant 2 1
              No-Reflow Phenomenon 3
              Non-ST Elevated Myocardial Infarction 0
              ST Elevation Myocardial Infarction 3
              acute myocardial infarction + 6
              anterolateral myocardial infarction + 2
              apical myocardial infarction 0
              inferior myocardial infarction 0
              inferolateral myocardial infarct 0
              lateral myocardial infarction 0
              myocardial stunning 4
              posterior myocardial infarction 0
              posteroinferior myocardial infarction 0
              posterolateral myocardial infarction 0
              septal myocardial infarction 0
              silent myocardial infarction 0
              subendocardial myocardial infarction 0
Path 2
Term Annotations click to browse term
  disease 15553
    disease of anatomical entity 14837
      cardiovascular system disease 4218
        vascular disease 3250
          ischemia 1279
            Myocardial Ischemia 805
              Coronary Disease 485
                coronary artery disease 462
                  myocardial infarction 350
                    Cardiogenic Shock 3
                    Coronary Artery Disease, Autosomal Dominant 1 1
                    Coronary Artery Disease, Autosomal Dominant 2 1
                    No-Reflow Phenomenon 3
                    Non-ST Elevated Myocardial Infarction 0
                    ST Elevation Myocardial Infarction 3
                    acute myocardial infarction + 6
                    anterolateral myocardial infarction + 2
                    apical myocardial infarction 0
                    inferior myocardial infarction 0
                    inferolateral myocardial infarct 0
                    lateral myocardial infarction 0
                    myocardial stunning 4
                    posterior myocardial infarction 0
                    posteroinferior myocardial infarction 0
                    posterolateral myocardial infarction 0
                    septal myocardial infarction 0
                    silent myocardial infarction 0
                    subendocardial myocardial infarction 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.