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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:congestive heart failure
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Accession:DOID:6000 term browser browse the term
Definition:A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Synonyms:exact_synonym: CHF;   Cardiac Failure;   Cardiac Failure Congestive;   Congestive heart disease;   Heart Decompensation;   Heart Failure;   Left Sided Heart Failure;   Myocardial Failure;   Right Sided Heart Failure;   Weak heart
 narrow_synonym: Chronic Heart Failure
 related_synonym: Beta-2-adrenoreceptor agonist, reduced response to;   Congestive heart failure and beta-blocker response, modifier of;   Congestive heart failure, modifier of
 primary_id: MESH:D006333;   RDO:0005421
 xref: ICD10CM:I50;   ICD10CM:I50.9;   ICD9CM:428;   ICD9CM:428.0;   NCI:C3080;   NCI:C50577
For additional species annotation, visit the Alliance of Genome Resources.


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congestive heart failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa1b acetyl-Coenzyme A acyltransferase 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 8:127,836,235...127,845,296 JBrowse link
G Acaca acetyl-CoA carboxylase alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acads acyl-CoA dehydrogenase short chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:30827304 NCBI chr12:47,254,503...47,263,747
Ensembl chr12:47,254,484...47,263,747
JBrowse link
G Acan aggrecan IEP mRNA:increased expression:myocardium RGD PMID:24595230 RGD:11570548 NCBI chr 1:140,762,758...140,824,441
Ensembl chr 1:140,762,758...140,824,441
JBrowse link
G Ace angiotensin I converting enzyme treatment IMP
IEP
ISO
associated with Myocardial Infarction
CTD Direct Evidence: marker/mechanism
associated with Hypertension
CTD PMID:18586661, PMID:19620082, PMID:15894569, PMID:22123369 RGD:2325224, RGD:12859272, RGD:6893472 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25973029 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Acly ATP citrate lyase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Actn2 actinin alpha 2 ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868 NCBI chr17:66,304,530...66,397,647
Ensembl chr17:66,304,501...66,397,653
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 treatment IEP associated with pulmonary hypertension RGD PMID:22628376 RGD:13703064 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO associated with cardiovascular disease; protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:19367012, PMID:26670611, PMID:22032915, PMID:18192035 RGD:5686388, RGD:5686806 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adm adrenomedullin IDA RGD PMID:12623952 RGD:704370 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adra2c adrenoceptor alpha 2C ISO DNA:deletion: :322_325del(human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Congestive heart failure and beta-blocker response, modifier of
CTD
ClinVar
PMID:12374873, PMID:17496726, PMID:12374873 RGD:1300355 NCBI chr14:80,730,307...80,732,010
Ensembl chr14:80,730,307...80,732,010
JBrowse link
G Adrb1 adrenoceptor beta 1 IMP
ISO
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Congestive heart failure and beta-blocker response, modifier of
DNA:polymorphism: :p.R389G (human)
CTD
ClinVar
PMID:7586371, PMID:10212248, PMID:12374873, PMID:14502278, PMID:15816327, PMID:16844790, PMID:17496726, PMID:21516734, PMID:19587314, PMID:14502278 RGD:5129119, RGD:737774 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Adrb2 adrenoceptor beta 2 IDA
ISO
IEP
ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to
protein:altered localization:cardiac muscle cell
ClinVar PMID:8383511, PMID:15284533, PMID:16596417, PMID:19587314, PMID:20185685 RGD:5129119, RGD:4144900 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Adrb3 adrenoceptor beta 3 ISO
IEP
protein:increased expression:left ventricle, myocardium (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:heart ventricle (rat)
CTD PMID:15009959, PMID:17440824, PMID:11273992, PMID:21549119 RGD:5684398, RGD:5684917 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
JBrowse link
G Ager advanced glycosylation end product-specific receptor severity ISO protein:increased expression:plasma (human) RGD PMID:20685687 RGD:7244134 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agt angiotensinogen onset
severity
treatment
ISO
IEP
DNA:polymorphisms: :p.M235T, p.T174M (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
CTD PMID:1330361, PMID:12025466, PMID:20811386, PMID:17145981, PMID:24465706, PMID:21963897 RGD:1601140, RGD:11039412, RGD:8549482 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a treatment IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:17208988, PMID:18214293, PMID:18586661, PMID:21963897 RGD:8549482 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Agtr2 angiotensin II receptor, type 2 IEP mRNA, protein:decreased expression:heart RGD PMID:18768398, PMID:21963897 RGD:6903846, RGD:8549482 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Akap6 A-kinase anchoring protein 6 ISO RGD PMID:24812305 RGD:11251930 NCBI chr 6:73,553,111...73,991,992
Ensembl chr 6:73,553,210...73,990,534
JBrowse link
G Akap9 A-kinase anchoring protein 9 ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:23861362, PMID:25741868, PMID:28492532 NCBI chr 4:27,195,346...27,331,582
Ensembl chr 4:27,195,346...27,331,582
JBrowse link
G Alb albumin disease_progression ISO CTD Direct Evidence: marker/mechanism CTD PMID:11771600, PMID:22158777 RGD:11036096 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type IEP RGD PMID:15623566 RGD:5509787 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Alox15 arachidonate 15-lipoxygenase IEP
ISO
associated with Myocardial Infarction; mRNA:increased expression:heart left ventricle, septum RGD PMID:16497176, PMID:19546247 RGD:1642301, RGD:5509627 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Ank2 ankyrin 2 ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Ankrd23 ankyrin repeat domain 23 ISO associated with Cardiomyopathy, Congestive RGD PMID:15238456 RGD:2314858 NCBI chr 9:43,110,980...43,117,585
Ensembl chr 9:43,112,141...43,116,521
JBrowse link
G Aoc3 amine oxidase, copper containing 3 severity ISO protein:increased expression:plasma RGD PMID:11052858 RGD:2313827 NCBI chr10:89,251,370...89,259,313
Ensembl chr10:89,251,370...89,259,313
JBrowse link
G Apcs amyloid P component, serum ISO CTD Direct Evidence: marker/mechanism CTD PMID:16129801 NCBI chr13:91,426,621...91,427,417
Ensembl chr13:91,426,479...91,427,575
JBrowse link
G Apln apelin IDA
IEP
ISO
associated with Hypertension, Pulmonary
protein:increased expression:ventricle myocardium
protein:decreased expression:plasma
RGD PMID:17055480, PMID:17119870, PMID:16263185 RGD:1626171, RGD:1626186, RGD:1626175 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210
JBrowse link
G Apoa1 apolipoprotein A1 ISO protein: decreased expression: serum RGD PMID:17517342 RGD:5508219 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoc1 apolipoprotein C1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G Apoe apolipoprotein E ISO associated with Beta-Thalassemia RGD PMID:9787187 RGD:11039487 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Arrb1 arrestin, beta 1 treatment IMP RGD PMID:21232674 RGD:5509888 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18418421 NCBI chr 1:81,852,423...81,881,565
Ensembl chr 1:81,852,429...81,881,549
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19776660 NCBI chr 1:197,855,912...197,875,038 JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:19776660, PMID:21691940 RGD:6903963 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Avp arginine vasopressin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18179782 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Avpr2 arginine vasopressin receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12145768 NCBI chr  X:156,889,006...156,892,707
Ensembl chr  X:156,889,410...156,891,213
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:18097624, PMID:29746994 RGD:10054097, RGD:13792577 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:18097624, PMID:29746994 RGD:10054097, RGD:13792577 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Becn1 beclin 1 treatment IEP RGD PMID:18619688 RGD:11560532 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 IEP associated with Hypertension;protein:decreased expression:cardiac muscle cell RGD PMID:16257070 RGD:2293134 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bnip3 BCL2 interacting protein 3 treatment IMP RGD PMID:23508759 RGD:11561982 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868, PMID:28492532 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Calr calreticulin ISS MouseDO NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Casp1 caspase 1 ISO protein:increased expression:heart left ventricle RGD PMID:17303764 RGD:2315913 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 treatment IEP associated with Hypertension
associated with myocardial infarction
RGD PMID:18787714, PMID:27346262 RGD:2311453, RGD:13782169 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:29746994 RGD:13792577 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casq2 calsequestrin 2 IEP mRNA:increased expression:sinoatrial node RGD PMID:21565973 RGD:6771208 NCBI chr 2:204,512,361...204,568,643
Ensembl chr 2:204,512,302...204,568,656
JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16105639, PMID:10618301 RGD:1581151 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbl Cbl proto-oncogene ISO protein:increased expression:left ventricle myocardium, muscle cell (human) RGD PMID:24583314 RGD:11251947 NCBI chr 8:48,481,256...48,564,775
Ensembl chr 8:48,489,036...48,564,722
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP
ISO
mRNA:increased expression:heart left ventricle
CTD Direct Evidence: marker/mechanism
CTD PMID:29959987, PMID:12950323 RGD:1581156 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccn2 cellular communication network factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17229371 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccna2 cyclin A2 ISO RGD PMID:16820573 RGD:2293348 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnt1 cyclin T1 ISO RGD PMID:15297879 RGD:1556509 NCBI chr 7:140,215,052...140,245,958
Ensembl chr 7:140,219,551...140,245,723
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO RGD PMID:12719858 RGD:1581177
G Cd40lg CD40 ligand ISO protein:increased expression:serum RGD PMID:15716285 RGD:2314219 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cdk9 cyclin-dependent kinase 9 ISO protein:increased activity:ventricle:
protein:increased activity:heart:
RGD PMID:15297879, PMID:15297879 RGD:1556509, RGD:1556509 NCBI chr 3:11,742,269...11,747,117
Ensembl chr 3:11,742,266...11,747,113
JBrowse link
G Cfd complement factor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator ISO mRNA,protein:increased expression:cardiomyocyte: RGD PMID:11033112 RGD:11341730 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Chek2 checkpoint kinase 2 ISO protein:increased phosphorylation:heart myocardium RGD PMID:12702777 RGD:2289708 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Chi3l1 chitinase 3 like 1 ISO protein:increased secretion:plasma (human) RGD PMID:19961288 RGD:4892629 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 IEP associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum RGD PMID:16497176 RGD:1642301 NCBI chr 3:80,833,272...80,841,165
Ensembl chr 3:80,833,272...80,841,006
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit IEP associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum RGD PMID:16497176 RGD:1642301 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Cidea cell death-inducing DFFA-like effector a ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051
JBrowse link
G Corin corin, serine peptidase IEP mRNA:decreased expression:left atrium, right atrium (rat)
mRNA:increased expression:heart (rat)
RGD PMID:15155264, PMID:15191894 RGD:1581218, RGD:1581217 NCBI chr14:38,247,379...38,474,931
Ensembl chr14:38,247,791...38,473,648
JBrowse link
G Crp C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16360360 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cryab crystallin, alpha B ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:1560021, PMID:16483541, PMID:16793013, PMID:17116488, PMID:20171888, PMID:21920752, PMID:22106715, PMID:22995991, PMID:23194663, PMID:23299917, PMID:24033266, PMID:25208129, PMID:25741868, PMID:26694549, PMID:26961874, PMID:28492532 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Cs citrate synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:8922916 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Csf2 colony stimulating factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11732872 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15585077 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 ISS MouseDO NCBI chr 1:104,147,205...104,166,389
Ensembl chr 1:104,147,206...104,166,367
JBrowse link
G Cst3 cystatin C susceptibility ISO protein:increased expression:serum (human) RGD PMID:19539088 RGD:2314311 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 IEP mRNA, protein:increased expression: paraventricular nucleus of hypothalamus RGD PMID:24036597 RGD:9491792 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cybb cytochrome b-245 beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 IEP protein:increased expression:heart (rat) RGD PMID:19571523 RGD:4891162 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 IEP associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum RGD PMID:16497176 RGD:1642301 NCBI chr 7:14,559,806...14,574,345
Ensembl chr 7:14,529,482...14,574,361
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 IEP associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum RGD PMID:16497176 RGD:1642301 NCBI chr20:3,553,430...3,574,959
Ensembl chr20:3,552,929...3,575,780
JBrowse link
G Dio3 iodothyronine deiodinase 3 IEP associated with Hypertrophy, Right Ventricular;mRNA, protein:increased expression:heart right ventricle RGD PMID:18259611 RGD:2303417 NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138
JBrowse link
G Dmd dystrophin ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:25741868, PMID:28492532 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Dnmt1 DNA methyltransferase 1 IEP protein:increased expression:atrium: RGD PMID:23573917 RGD:9588286 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dstn destrin, actin depolymerizing factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr 3:138,024,508...138,051,304
Ensembl chr 3:138,024,508...138,051,298
JBrowse link
G Dynll1 dynein light chain LC8-type 1 IEP protein:increased expression:paraventricular nucleus RGD PMID:23832698 RGD:7257598 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G Ece1 endothelin converting enzyme 1 ISO
IEP
IMP
mRNA,protein:increased expression:kidney:
associated with myocardial ischemia
RGD PMID:11145756, PMID:9595392, PMID:19596829 RGD:1580911, RGD:7244244, RGD:7243876 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
JBrowse link
G Edn1 endothelin 1 severity
treatment
ISO
IEP
protein:increased secretion:plasma (human)
CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:heart:
CTD PMID:7967349, PMID:7969316, PMID:9861300, PMID:11136700, PMID:11707688, PMID:16360360, PMID:16762801, PMID:8149524, PMID:10973842, PMID:10199843 RGD:4144845, RGD:8661798, RGD:7244167 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ednra endothelin receptor type A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28095452 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Ednrb endothelin receptor type B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28095452 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G Endog endonuclease G IEP mRNa:decreased expression:heart: RGD PMID:17292393 RGD:9685393 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
JBrowse link
G Eng endoglin treatment IEP
IDA
protein:increased expression:heart left ventricle (rat) RGD PMID:20156938, PMID:20156938 RGD:7257540, RGD:7257540 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Ep300 E1A binding protein p300 ISO RGD PMID:12724418 RGD:2312280 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18443590 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Epo erythropoietin treatment ISO associated with Myocardial Infarction RGD PMID:20139114 RGD:10401073 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 IEP RGD PMID:10421602 RGD:1580989 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 IEP associated with Aortic Valve Stenosis;mRNA, protein:decreased expression:heart myocardium RGD PMID:10421602 RGD:1580989 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
JBrowse link
G Esrra estrogen related receptor, alpha ISO protein:decreased expression:heart: RGD PMID:21825219 RGD:10401867 NCBI chr 1:222,168,729...222,178,842
Ensembl chr 1:222,168,730...222,178,725
JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 ISO DNA:deletion:introns, exon (human)
ClinVar Annotator: match by term: Congestive heart failure
ClinVar PMID:25741868, PMID:28492532, PMID:15735644 RGD:1598455 NCBI chr 1:23,237,617...23,611,580
Ensembl chr 1:23,409,408...23,610,164
JBrowse link
G Fas Fas cell surface death receptor treatment ISO
IEP
mRNA:splice variant:heart left ventricle (human) RGD PMID:9367848, PMID:29746994 RGD:8686420, RGD:13792577 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand treatment IEP RGD PMID:29746994 RGD:13792577 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbln5 fibulin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12189163 NCBI chr 6:125,644,797...125,723,957
Ensembl chr 6:125,644,804...125,723,944
JBrowse link
G Fip1l1 factor interacting with PAPOLA and CPSF1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28347583 NCBI chr14:36,150,381...36,208,395
Ensembl chr14:36,150,399...36,208,373
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B IEP associated with Shock, Septic RGD PMID:17637193 RGD:2302075 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP RGD PMID:15623567 RGD:2293777 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit IEP RGD PMID:15623567 RGD:2293777 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Foxc1 forkhead box C1 ISO RGD PMID:16952980 RGD:1582564 NCBI chr17:33,947,501...33,951,484
Ensembl chr17:33,947,506...33,951,484
JBrowse link
G Foxc2 forkhead box C2 ISO RGD PMID:16952980 RGD:1582564 NCBI chr19:53,044,379...53,047,081
Ensembl chr19:53,044,379...53,047,081
JBrowse link
G Foxo1 forkhead box O1 ISO RGD PMID:16952980 RGD:1582564 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Foxp1 forkhead box P1 ISO RGD PMID:16952980 RGD:1582564 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G Foxp4 forkhead box P4 ISO RGD PMID:16952980 RGD:1582564 NCBI chr 9:15,068,378...15,124,962
Ensembl chr 9:15,068,399...15,125,318
JBrowse link
G Fth1 ferritin heavy chain 1 IEP protein:decreased expression:heart RGD PMID:18992754 RGD:2315110 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 IEP protein:increased serine phosphorylation:heart, membrane RGD PMID:26668322 RGD:11526267 NCBI chr 1:89,484,197...89,488,279
Ensembl chr 1:89,484,199...89,488,223
JBrowse link
G Gatm glycine amidinotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16820567 NCBI chr 3:114,711,570...114,728,155
Ensembl chr 3:114,711,562...114,728,410
JBrowse link
G Gcg glucagon ISO CTD Direct Evidence: therapeutic CTD PMID:7608802 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
JBrowse link
G Gdf15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20855664 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:20572026 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Gnaq G protein subunit alpha q ISS MouseDO NCBI chr 1:233,382,778...233,622,584
Ensembl chr 1:233,382,708...233,622,786
JBrowse link
G Gpx4 glutathione peroxidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Grk1 G protein-coupled receptor kinase 1 IDA RGD PMID:12456492 RGD:1600002 NCBI chr16:81,153,489...81,165,442
Ensembl chr16:81,153,489...81,165,442
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 treatment IEP
ISO
associated with Hypertrophy, Left Ventricular and Hypertension;protein:increased expression, increased activity:heart left ventricle, cytosol (rat)
mRNA:decreased expression:peripheral blood mononuclear cell (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:26670611, PMID:9931137, PMID:26248277, PMID:29247373, PMID:11331748 RGD:1625790, RGD:11535540, RGD:13506830, RGD:737776 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Grk3 G protein-coupled receptor kinase 3 severity ISO mRNA:decreased expression:heart left ventricle (human) RGD PMID:22685168 RGD:13506835 NCBI chr12:49,626,871...49,750,389
Ensembl chr12:49,626,871...49,746,272
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 severity ISO mRNA:decreased expression:heart left ventricle (human)
mRNA:decreased expression:peripheral blood mononuclear cell (human)
RGD PMID:22685168, PMID:26248277 RGD:13506835, RGD:11535540 NCBI chr 1:282,265,371...282,467,842
Ensembl chr 1:282,265,370...282,462,605
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17901358 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Hamp hepcidin antimicrobial peptide ISO protein:increased expression:serum, urine RGD PMID:21080339 RGD:11041621 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546
JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868, PMID:28492532 NCBI chr 8:63,599,907...63,637,327
Ensembl chr 8:63,600,663...63,639,654
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP
ISO
protein:increased expression:heart right ventricle (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:15732037, PMID:17582388 RGD:9068910 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgb1 high mobility group box 1 treatment ISO
IMP
protein:decreased expression:heart RGD PMID:23708738, PMID:24204700 RGD:10402070, RGD:10402081 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 treatment IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:22352330, PMID:23592614 RGD:10755584 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hp haptoglobin treatment IEP RGD PMID:23494325 RGD:11041812 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hrh2 histamine receptor H 2 susceptibility ISO RGD PMID:24655024 RGD:9685523 NCBI chr17:10,912,959...10,931,389
Ensembl chr17:10,921,507...10,952,441
JBrowse link
G Hsf1 heat shock transcription factor 1 IEP protein:altered localization:heart left ventricle (rat) RGD PMID:24285117 RGD:10402754 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: therapeutic CTD PMID:17481944 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IDA mRNA:increased expression:heart left ventricle RGD PMID:16002744 RGD:1600503 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B IEP
ISO
mRNA:increased expression:left ventricle cardiac muscle (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:19023134, PMID:17936780 RGD:9698457 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:3091246, PMID:20938210 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 IEP RGD PMID:12835956 RGD:1598415 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il10 interleukin 10 disease_progression
treatment
IEP RGD PMID:16461369, PMID:28939262, PMID:23778495 RGD:1598465, RGD:14975271, RGD:7365020 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il17a interleukin 17A IEP
IMP
protein:increased expression:heart RGD PMID:19909738, PMID:19527710 RGD:2325816, RGD:4831836 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:15135663 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 IEP
ISO
IDA
associated with Hypertension;mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental; protein:increased expression:extracellular space (rat)
CTD PMID:15135663, PMID:16360360, PMID:18280594, PMID:28939262, PMID:18999900 RGD:5128682, RGD:14975271, RGD:2307285 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor IEP protein:increased expression:paraventricular hypothalamic nucleus RGD PMID:17095650 RGD:1625433 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Ins2 insulin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15628829 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Itgb1 integrin subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11884376 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Kat8 lysine acetyltransferase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27768893 NCBI chr 1:199,360,645...199,372,925
Ensembl chr 1:199,360,645...199,372,923
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IEP
ISO
associated with Myocardial Infarction (RDO:0006167); mRNA:increased expression:heart left ventricle, septum
mRNA:increased expression:endocardium of right ventricle:
RGD PMID:16497176, PMID:17384445 RGD:1642301, RGD:12910696 NCBI chr11:32,498,260...32,511,202
Ensembl chr11:32,498,261...32,508,420
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 IEP associated with Hypertension, Pulmonary:mRNA:decreased expression:heart right ventricle (rat) RGD PMID:25016242 RGD:9831185 NCBI chr13:107,690,111...107,886,476
Ensembl chr13:107,690,087...107,886,476
JBrowse link
G Kdm2a lysine demethylase 2A ISO protein:altered localization:promoter (mouse) RGD PMID:25181347 RGD:9588275 NCBI chr 1:219,566,130...219,642,294
Ensembl chr 1:219,566,156...219,640,294
JBrowse link
G Lep leptin ISO RGD PMID:18006469 RGD:5128823 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lepr leptin receptor ISO protein:increased phosphorylation:heart RGD PMID:18006469 RGD:5128823 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lgals3 galectin 3 IEP RGD PMID:15520318 RGD:9685214 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lif LIF, interleukin 6 family cytokine IEP RGD PMID:20051627 RGD:2326058 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21284947 NCBI chr12:2,546,278...2,555,310
Ensembl chr12:2,548,218...2,555,164
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO protein:increased activity:heart: RGD PMID:17562954 RGD:10412331 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor IEP mRNA, protein:decreased expression:heart RGD PMID:21963897 RGD:8549482 NCBI chr 1:48,076,761...48,108,218
Ensembl chr 1:48,077,033...48,108,216
JBrowse link
G Mdh2 malate dehydrogenase 2 IDA RGD PMID:16786185 RGD:1582470 NCBI chr12:23,941,451...23,954,406
Ensembl chr12:23,941,448...23,954,431
JBrowse link
G Med1 mediator complex subunit 1 ISS MouseDO NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Mir27a microRNA 27a IEP RNA:increased expression:heart RGD PMID:29373037 RGD:26923905 NCBI chr19:25,318,736...25,318,822
Ensembl chr19:25,318,736...25,318,822
JBrowse link
G Mir28 microRNA 28 IEP RNA:increased expression:heart RGD PMID:29373037 RGD:26923905 NCBI chr11:79,380,523...79,380,608
Ensembl chr11:79,380,523...79,380,608
JBrowse link
G Mir34a microRNA 34a IEP RNA:increased expression:heart RGD PMID:29373037 RGD:26923905 NCBI chr 5:167,092,491...167,092,592
Ensembl chr 5:167,092,491...167,092,592
JBrowse link
G Mme membrane metallo-endopeptidase IEP RGD PMID:12383878 RGD:13801043 NCBI chr 2:153,799,203...153,880,910
Ensembl chr 2:153,803,349...153,880,738
JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO
IDA
RGD PMID:12892382, PMID:21866669 RGD:1582539, RGD:7207282 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp13 matrix metallopeptidase 13 disease_progression IEP protein:increased expression:left ventricle (rat)
associated with Hypertension
RGD PMID:10773235, PMID:10773234 RGD:1582587, RGD:2290467 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp14 matrix metallopeptidase 14 disease_progression IEP protein:increased expression:left ventricle (rat) RGD PMID:10773235 RGD:1582587 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
JBrowse link
G Mmp2 matrix metallopeptidase 2 severity IEP
ISO
mRNA:increased expression:heart left ventricle
protein:increased expression:heart left ventricle, plasma
RGD PMID:10773234, PMID:20606426, PMID:16169329 RGD:2290467, RGD:8694112, RGD:1582574 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO protein:increased expression:heart left ventricle, plasma RGD PMID:20606426 RGD:8694112 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp8 matrix metallopeptidase 8 disease_progression IEP protein:increased expression:left ventricle (rat) RGD PMID:10773235 RGD:1582587 NCBI chr 8:5,768,808...5,777,741
Ensembl chr 8:5,768,811...5,778,702
JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP
ISO
IDA
associated with Hypertension, Pulmonary; protein:increased expression:heart
protein:increased expression:heart left ventricle, plasma
RGD PMID:17913382, PMID:20606426, PMID:11342481, PMID:16952784 RGD:5130174, RGD:8694112, RGD:7207137, RGD:1582647 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mstn myostatin IEP
ISO
mRNA, protein:increased expression:myocardium
CTD Direct Evidence: marker/mechanism
CTD PMID:16968467, PMID:16968467 RGD:2303554 NCBI chr 9:53,310,977...53,315,804
Ensembl chr 9:53,309,598...53,315,915
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO mRNA, protein:increased expression:heart RGD PMID:20861467 RGD:10003169 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mtpn myotrophin ISS MouseDO NCBI chr 4:63,012,009...63,039,422
Ensembl chr 4:63,012,011...63,039,422
JBrowse link
G Myh6 myosin heavy chain 6 treatment ISO
IEP
mRNA:decreased expression:heart left ventricle
ClinVar Annotator: match by term: Heart failure
ClinVar Annotator: match by term: Congestive heart failure
associated with Myocardial Infarction
ClinVar PMID:20656787, PMID:23861362, PMID:24033266, PMID:25741868, PMID:28492532, PMID:9410916, PMID:18088389 RGD:1580923, RGD:12792974 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Myh7 myosin heavy chain 7 treatment IEP associated with Myocardial Infarction RGD PMID:18088389 RGD:12792974 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Myod1 myogenic differentiation 1 treatment IDA associated with Aortic Valve Stenosis RGD PMID:20060348 RGD:9686081 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248
JBrowse link
G Myot myotilin ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:25741868, PMID:28492532 NCBI chr18:35,573,978...35,593,541
Ensembl chr18:35,574,002...35,593,541
JBrowse link
G Mypn myopalladin ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:22286171, PMID:23299917, PMID:24033266, PMID:25741868, PMID:28492532 NCBI chr20:26,988,820...27,074,106
Ensembl chr20:26,988,774...27,074,138
JBrowse link
G Ncam1 neural cell adhesion molecule 1 IEP mRNA, protein:increased expression:heart RGD PMID:19853610 RGD:2325979 NCBI chr 8:53,836,797...54,134,881
Ensembl chr 8:53,839,098...53,901,358
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO
IEP
CTD Direct Evidence: therapeutic CTD PMID:28373008, PMID:29373037 RGD:26923905 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Ngfr nerve growth factor receptor IEP associated with Myocardial Infarction ;mRNA:increased expression:heart left ventricle, septum (rat) RGD PMID:16497176 RGD:1642301 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nisch nischarin ISO RGD PMID:12021582 RGD:1581128 NCBI chr16:7,254,372...7,290,670
Ensembl chr16:7,254,974...7,290,561
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 ISO protein:increased expression:heart, left ventricle, sarcolemma (human) RGD PMID:11121795 RGD:5132888 NCBI chr10:81,648,216...81,653,717
Ensembl chr10:81,648,216...81,653,717
JBrowse link
G Nos1 nitric oxide synthase 1 IEP RGD PMID:15466641, PMID:23832698 RGD:1581144, RGD:7257598 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein IEP mRNA:increased expression:brain RGD PMID:21831995 RGD:7327163 NCBI chr13:88,653,123...88,943,976 JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19168511 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:19168511, PMID:20304815, PMID:29351461 RGD:13504746 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nox1 NADPH oxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Nox4 NADPH oxidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr 1:150,796,359...150,976,186
Ensembl chr 1:150,797,084...150,976,194
JBrowse link
G Nppa natriuretic peptide A treatment
severity
ISO
IDA
mRNA,protein:increased expression:heart,plasma
CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma
CTD PMID:1647690, PMID:8112904, PMID:11136700, PMID:16101196, PMID:11421854, PMID:23931972, PMID:23566312, PMID:2143809 RGD:1580139, RGD:7297049, RGD:7247714, RGD:1580140 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nppb natriuretic peptide B severity ISO
IEP
protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism|therapeutic
associated with Diabetes Mellitus;protein:increased expression:plasma
mRNA,protein:increased expression:heart,plasma
CTD PMID:11136700, PMID:11279304, PMID:12628948, PMID:15732037, PMID:15860969, PMID:16101196, PMID:16333235, PMID:16360360, PMID:16762801, PMID:16777915, PMID:19650993, PMID:24535859, PMID:29959987, PMID:2143809, PMID:1831369, PMID:17257273, PMID:11421854 RGD:1580140, RGD:7247316, RGD:1642196, RGD:1580139 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Npr1 natriuretic peptide receptor 1 ISO associated with Hypertension
CTD Direct Evidence: marker/mechanism
protein:decreased expression:kidney
CTD PMID:20881240, PMID:9405681, PMID:17264312 RGD:737701, RGD:7247730 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090
JBrowse link
G Nptxr neuronal pentraxin receptor IEP associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum RGD PMID:16497176 RGD:1642301 NCBI chr 7:121,011,678...121,029,754
Ensembl chr 7:121,011,680...121,029,754
JBrowse link
G Npy neuropeptide Y IEP RGD PMID:17804485 RGD:7175103 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment IMP RGD PMID:21737535 RGD:7174712 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15722665, PMID:21321305 NCBI chr19:34,408,275...34,761,003
Ensembl chr19:34,448,289...34,752,695
JBrowse link
G Nrg1 neuregulin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19801490 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22503866 NCBI chr11:14,658,225...14,742,478
Ensembl chr11:14,658,225...14,741,563
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase IEP protein:increased expression:heart left ventricle (rat) RGD PMID:22128088 RGD:9590202 NCBI chr  X:71,540,870...71,585,906
Ensembl chr  X:71,528,988...71,585,908
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr 4:163,239,853...163,261,937
Ensembl chr 4:163,239,849...163,261,958
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase IEP protein:decreased expression:heart RGD PMID:19493956 RGD:7800717 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G P2rx4 purinergic receptor P2X 4 IEP associated with Myocardial Infarction (CTD:0006167); mRNA:increased expression:heart left ventricle, septum RGD PMID:16497176 RGD:1642301 NCBI chr12:39,308,022...39,325,673
Ensembl chr12:39,308,025...39,325,673
JBrowse link
G Pamr1 peptidase domain containing associated with muscle regeneration 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28751527 NCBI chr 3:92,403,533...92,502,094
Ensembl chr 3:92,403,582...92,502,089
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 treatment IMP associated with Hypertension RGD PMID:19443425 RGD:11074236 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 ISO protein:decreased expression:heart: RGD PMID:23647599 RGD:10448278 NCBI chr 1:1,734,863...1,767,759
Ensembl chr 1:1,736,276...1,767,618
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:28347583 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19429709 NCBI chr10:13,446,373...13,525,248
Ensembl chr10:13,451,624...13,515,448
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr12:45,026,948...45,031,148
Ensembl chr12:45,026,886...45,031,145
JBrowse link
G Pgf placental growth factor IDA RGD PMID:19327525 RGD:6483590 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:12963636, PMID:15936620 RGD:6482699 NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337
JBrowse link
G Pkp2 plakophilin 2 ISO ClinVar Annotator: match by term: CHF ClinVar PMID:22035158, PMID:25445213, PMID:25741868, PMID:28492532, PMID:30311386 NCBI chr11:88,912,163...88,972,213 JBrowse link
G Pla2g7 phospholipase A2 group VII ISO RGD PMID:16952920 RGD:6482778 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plcd1 phospholipase C, delta 1 IDA RGD PMID:11181012 RGD:2300431 NCBI chr 8:127,753,514...127,782,070
Ensembl chr 8:127,753,539...127,782,070
JBrowse link
G Pld2 phospholipase D2 IEP protein:increased expression:heart left ventricle RGD PMID:15601581 RGD:2299908 NCBI chr10:57,161,921...57,181,148
Ensembl chr10:57,163,174...57,179,730
JBrowse link
G Pln phospholamban treatment IDA associated with Hypertension
associated with Myocardial Infarction
RGD PMID:22970977, PMID:22947202 RGD:7327181, RGD:7327182 NCBI chr20:34,633,157...34,642,904
Ensembl chr20:34,633,157...34,642,904
JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:3026683, PMID:8277081 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Postn periostin treatment ISO
IMP
mRNA:increased expression:heart RGD PMID:16414453, PMID:15381649 RGD:10040951, RGD:10040999 NCBI chr 2:143,656,820...143,688,087
Ensembl chr 2:143,656,793...143,688,087
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha onset ISO CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:heart (mouse)
CTD PMID:19808358, PMID:22503866, PMID:23342071, PMID:23297372 RGD:7241838, RGD:7241843 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha ISO RGD PMID:12024026 RGD:737728 NCBI chr 1:219,439,953...219,443,570
Ensembl chr 1:219,439,953...219,443,570
JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma IEP protein:increased expression:heart, membrane RGD PMID:26668322 RGD:11526267 NCBI chr12:39,864,302...39,882,030
Ensembl chr12:39,864,295...39,882,030
JBrowse link
G Ppp1r1a protein phosphatase 1, regulatory (inhibitor) subunit 1A ISO CTD Direct Evidence: therapeutic CTD PMID:20071777 NCBI chr 7:145,146,480...145,154,131
Ensembl chr 7:145,146,481...145,154,131
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO mRNA:increased expression:vastus lateralis muscle (human) RGD PMID:14567976 RGD:8693707 NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha ISO RGD PMID:10830164 RGD:1580714 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 ISO ClinVar Annotator: match by term: Congestive heart failure
ClinVar Annotator: match by term: Heart failure
ClinVar PMID:21409595, PMID:24033266, PMID:25741868, PMID:27532257, PMID:28492532 NCBI chr 4:6,559,153...6,799,888
Ensembl chr 4:6,559,545...6,799,632
JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha ISO RGD PMID:10830164 RGD:1580714 NCBI chr 8:117,486,085...117,548,768
Ensembl chr 8:117,486,083...117,546,370
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 6:51,265,509...51,356,383
Ensembl chr 6:51,265,515...51,356,383
JBrowse link
G Prkca protein kinase C, alpha IEP protein:increased expression, increased phosphorylation:heart left ventricle RGD PMID:17556659 RGD:2292480 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prkcb protein kinase C, beta IEP associated with hypertension RGD PMID:12392998 RGD:1625516 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prl prolactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18926768 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Psen1 presenilin 1 ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:17186461, PMID:25741868, PMID:28492532 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pth parathyroid hormone ISO protein:increased expression:serum (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:17162251, PMID:21939825 RGD:7242422 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F ISO CTD Direct Evidence: marker/mechanism CTD PMID:28751527 NCBI chr 5:137,036,936...137,112,930
Ensembl chr 5:137,036,935...137,112,927
JBrowse link
G Rac1 Rac family small GTPase 1 IAGP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:16155095, PMID:12642504 RGD:1581295 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Ramp2 receptor activity modifying protein 2 IEP associated with Hypertension RGD PMID:12623952 RGD:704370 NCBI chr10:89,166,170...89,168,962
Ensembl chr10:89,166,890...89,168,965
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 ISO mRNA, protein:increased expression:left ventricle myocardium (human) RGD PMID:18323524 RGD:9835356 NCBI chr 7:139,232,263...139,254,668
Ensembl chr 7:139,232,251...139,254,551
JBrowse link
G Rbm20 RNA binding motif protein 20 ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:25741868, PMID:28492532 NCBI chr 1:274,391,932...274,589,816
Ensembl chr 1:274,391,932...274,589,816
JBrowse link
G Rbp4 retinol binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 1:256,806,476...256,813,678
Ensembl chr 1:256,806,472...256,813,711
JBrowse link
G Ren renin ISO CTD Direct Evidence: marker/mechanism CTD PMID:1647690, PMID:7034517, PMID:20811386 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Retn resistin ISO associated with Coronary Disease
CTD Direct Evidence: marker/mechanism
CTD PMID:26670611, PMID:22240747 RGD:7207075 NCBI chr12:2,201,909...2,203,649
Ensembl chr12:2,201,891...2,204,249
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase IEP RGD PMID:21297953 RGD:7327162 NCBI chr 1:251,828,285...252,101,963
Ensembl chr 1:251,828,290...252,100,759
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator ISO mRNA, protein:decreased expression:heart RGD PMID:18056528 RGD:2311701 NCBI chr19:561,696...564,929
Ensembl chr19:561,727...564,930
JBrowse link
G Ryr2 ryanodine receptor 2 IDA
ISO
ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:25741868, PMID:16483256 RGD:1599251 NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606
JBrowse link
G Scd stearoyl-CoA desaturase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 IEP mRNA:decreased expression:ventricle myocardium RGD PMID:19584134 RGD:6484224 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 IEP mRNA:increased expression:ventricle myocardium RGD PMID:19584134 RGD:6484224 NCBI chr 7:142,575,629...142,683,659
Ensembl chr 7:142,575,672...142,684,114
JBrowse link
G Selp selectin P IEP RGD PMID:19193626 RGD:2312309 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpine1 serpin family E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:24535859 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Sirt3 sirtuin 3 IEP protein:decreased expression:heart left ventricle RGD PMID:22155497 RGD:9586040 NCBI chr 1:213,613,502...213,636,061
Ensembl chr 1:213,613,513...213,635,546
JBrowse link
G Slc2a4 solute carrier family 2 member 4 severity ISO protein:decreased expression:skeletal muscle RGD PMID:18778861 RGD:2313624 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO DNA:repeat:promoter (human) RGD PMID:17307423 RGD:4889438 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
G Slc8a1 solute carrier family 8 member A1 IEP protein:increased expression:cardiac muscle cell RGD PMID:17536604 RGD:1642720 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
G Slc9a1 solute carrier family 9 member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027022, PMID:18776042 RGD:6771337 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16105639, PMID:16155095, PMID:20304815, PMID:21195081, PMID:21284947 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20304815 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Sox4 SRY-box transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Srf serum response factor ISO mRNA, protein:splice variant:heart RGD PMID:11893590 RGD:1581426 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225
JBrowse link
G Sri sorcin IEP protein:decreased expression:cardiac muscle cell
associated with Hypertension
RGD PMID:20945956, PMID:12754254 RGD:7327198, RGD:7327200 NCBI chr 4:23,004,657...23,029,233
Ensembl chr 4:23,006,243...23,018,983
JBrowse link
G Tbx20 T-box transcription factor 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr 8:25,849,394...25,904,570
Ensembl chr 8:25,850,962...25,904,570
JBrowse link
G Th tyrosine hydroxylase IEP
ISO
protein:increased expression:paraventricular thalamic nucleus (rat) RGD PMID:21287352, PMID:7715703 RGD:5128674, RGD:737737 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 IEP protein:increased expression:heart left ventricle RGD PMID:10773234 RGD:2290467 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 IEP protein:increased expression:heart left ventricle RGD PMID:10773234 RGD:2290467 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 IEP protein:decreased expression:heart left ventricle RGD PMID:10773234 RGD:2290467 NCBI chr 4:147,156,948...147,163,467
Ensembl chr 4:147,156,948...147,163,467
JBrowse link
G Tlr2 toll-like receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tnf tumor necrosis factor treatment
severity
IMP
IEP
ISO
CTD Direct Evidence: marker/mechanism
associated with Myocardial Infarction;
CTD PMID:15135663, PMID:15231041, PMID:17337591, PMID:18034274, PMID:29959987, PMID:15210453, PMID:28939262, PMID:11668085, PMID:11100001 RGD:1580213, RGD:14975271, RGD:7401242, RGD:7401241 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B IEP mRNA, protein:incereased expression:myocardium RGD PMID:15883214 RGD:1624176 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16360360 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO human protein in rat model RGD PMID:21135513 RGD:5131262 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Tnnt2 troponin T2, cardiac type ISO CTD Direct Evidence: marker/mechanism CTD PMID:12322705, PMID:17698733 NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990
JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 ISO
IDA
mRNA:decreased expression:heart
protein:increased serine phosphorylation:heart, mitochondrion
RGD PMID:25022898, PMID:24395194 RGD:13464131, RGD:13464132 NCBI chr11:45,477,053...45,511,409
Ensembl chr11:45,480,250...45,510,961
JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21284947 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Ttn titin ISO ClinVar Annotator: match by term: Congestive heart failure
ClinVar Annotator: match by term: Heart failure
ClinVar Annotator: match by term: CHF
ClinVar PMID:15802564, PMID:23396983, PMID:23486992, PMID:23861362, PMID:24033266, PMID:24055113, PMID:24231549, PMID:24271327, PMID:24503780, PMID:24569025, PMID:24578547, PMID:25589632, PMID:25741868, PMID:26272908, PMID:26383259, PMID:26467025, PMID:26498160, PMID:26516846, PMID:27194543, PMID:27843123, PMID:28256728, PMID:28492532, PMID:29361395, PMID:30311386 NCBI chr 3:63,565,160...63,837,815 JBrowse link
G Ttr transthyretin ISO ClinVar Annotator: match by term: Heart failure ClinVar PMID:1355416, PMID:1850190, PMID:1997217, PMID:2174830, PMID:2590199, PMID:6736244, PMID:7923855, PMID:8102146, PMID:9090525, PMID:14640030, PMID:15185492, PMID:19428025, PMID:22332999, PMID:24033266, PMID:24955979, PMID:25741868, PMID:28492532 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
G Tubb5 tubulin, beta 5 class I ISO CTD Direct Evidence: marker/mechanism CTD PMID:16155095 NCBI chr20:3,422,448...3,426,420
Ensembl chr20:3,422,461...3,426,371
JBrowse link
G Ucn urocortin ISO protein:increased secretion:plasma (human) RGD PMID:19808377 RGD:5490589 NCBI chr 6:26,602,144...26,602,974
Ensembl chr 6:26,602,144...26,602,974
JBrowse link
G Ucn2 urocortin 2 ISO mRNA, protein:increased expression:myocardium (human)
CTD Direct Evidence: therapeutic
CTD PMID:16330704, PMID:12076554 RGD:5508210 NCBI chr 8:117,727,216...117,728,765
Ensembl chr 8:117,727,877...117,728,764
JBrowse link
G Ucp1 uncoupling protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26670611 NCBI chr19:24,456,976...24,464,808
Ensembl chr19:24,456,976...24,464,807
JBrowse link
G Ucp2 uncoupling protein 2 IEP protein:decreased expression:heart, mitochondria RGD PMID:20809120, PMID:20193183 RGD:7204424, RGD:7204426 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Ucp3 uncoupling protein 3 IEP protein:decreased expression:heart, mitochondria RGD PMID:20809120 RGD:7204424 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206
JBrowse link
G Uts2 urotensin 2 severity ISO protein:increased expression:plasma RGD PMID:16364499, PMID:12791592 RGD:2306804, RGD:1580809 NCBI chr 5:168,078,748...168,084,133
Ensembl chr 5:168,078,748...168,084,145
JBrowse link
G Vcl vinculin ISO ClinVar Annotator: match by term: Congestive heart failure ClinVar PMID:24033266, PMID:28492532 NCBI chr15:3,455,211...3,544,738
Ensembl chr15:3,455,211...3,544,702
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:15732037, PMID:15880336 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vwf von Willebrand factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
G Wfdc6a WAP four-disulfide core domain 6A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16436767 NCBI chr 3:161,036,703...161,040,511
Ensembl chr 3:161,036,703...161,040,511
JBrowse link
G Xdh xanthine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19933411 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Yy1 YY1 transcription factor ISO RGD PMID:12754214 RGD:1580831 NCBI chr 6:132,702,443...132,726,848
Ensembl chr 6:132,702,448...132,727,046
JBrowse link
Alcohol-Induced Sudden Cardiac Failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppa2 inorganic pyrophosphatase 2 ISO ClinVar Annotator: match by term: Sudden cardiac failure, alcohol-induced ClinVar
OMIM
PMID:25741868, PMID:27523597, PMID:27523598, PMID:28492532, PMID:30384889 NCBI chr 2:238,528,978...238,606,903
Ensembl chr 2:238,529,074...238,606,905
JBrowse link
cardiac arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 treatment IMP RGD PMID:26010685 RGD:12791997 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Akap9 A-kinase anchoring protein 9 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:23861362, PMID:28492532 NCBI chr 4:27,195,346...27,331,582
Ensembl chr 4:27,195,346...27,331,582
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO RGD PMID:20363892 RGD:5509101 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Ank2 ankyrin 2 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:28492532, PMID:28600387 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:21383000, PMID:22840528, PMID:25527503, PMID:28492532 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:28492532, PMID:30311386 NCBI chr17:81,673,862...82,019,219
Ensembl chr17:81,798,756...82,017,682
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP protein:increased expression:hippocampus (rat) RGD PMID:19756023 RGD:4889980 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Cep85l centrosomal protein 85-like ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:12639993, PMID:16235537, PMID:17655857, PMID:21167350, PMID:21332051, PMID:22137083, PMID:23861362, PMID:24033266, PMID:25611685, PMID:25741868, PMID:26535225, PMID:27532257, PMID:28492532, PMID:28600387 NCBI chr20:34,574,043...34,743,142
Ensembl chr20:34,575,950...34,684,418
JBrowse link
G Dpp6 dipeptidyl peptidase like 6 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chr 4:4,021,021...4,943,675
Ensembl chr 4:4,021,008...4,473,307
JBrowse link
G Dsc2 desmocollin 2 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:18678517, PMID:23861362, PMID:24033266, PMID:24704780, PMID:25637381, PMID:25741868, PMID:27153395, PMID:28492532 NCBI chr18:11,826,705...11,858,801
Ensembl chr18:11,826,706...11,858,754
JBrowse link
G Dsg2 desmoglein 2 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:20400443, PMID:23861362, PMID:24070718, PMID:25741868, PMID:28492532, PMID:28600387 NCBI chr18:15,579,322...15,637,720
Ensembl chr18:15,579,315...15,637,715
JBrowse link
G Dsp desmoplakin ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:21606390, PMID:25525159, PMID:25741868, PMID:28492532 NCBI chr17:27,286,811...27,334,453
Ensembl chr17:27,286,796...27,334,379
JBrowse link
G Dynll1 dynein light chain LC8-type 1 IEP RGD PMID:9522364 RGD:13208524 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G Ep300 E1A binding protein p300 ISO associated with Diabetes Mellitus; mRNA:increased expression:blood (human) RGD PMID:19577077 RGD:2312286 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:17728042 RGD:5688386 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:28492532, PMID:30311386 NCBI chr 8:122,957,570...122,987,236
Ensembl chr 8:122,954,948...122,987,191
JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:28492532 NCBI chr 8:63,599,907...63,637,327
Ensembl chr 8:63,600,663...63,639,654
JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:9806674 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il18 interleukin 18 IEP RGD PMID:18679114 RGD:4889454 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Ins2 insulin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:17449947 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 IEP protein:increased expression:cerebellum (rat) RGD PMID:21859719 RGD:6480675 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
G Mybpc3 myosin binding protein C3 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:14563344, PMID:15519027, PMID:16352453, PMID:20624503, PMID:22361390, PMID:23140321, PMID:23299917, PMID:23785128, PMID:24033266, PMID:24503780, PMID:24510615, PMID:25163546, PMID:25741868, PMID:28492532 NCBI chr 3:79,940,509...79,958,731
Ensembl chr 3:79,940,561...79,958,730
JBrowse link
G Myh6 myosin heavy chain 6 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Myom1 myomesin 1 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chr 9:119,353,840...119,469,196
Ensembl chr 9:119,353,840...119,468,715
JBrowse link
G Nsun6 NOP2/Sun RNA methyltransferase 6 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:28492532, PMID:30311386 NCBI chr17:82,020,316...82,060,533
Ensembl chr17:82,022,490...82,060,123
JBrowse link
G Pln phospholamban ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:12639993, PMID:16235537, PMID:17655857, PMID:21167350, PMID:21332051, PMID:22137083, PMID:23861362, PMID:24033266, PMID:25611685, PMID:25741868, PMID:26535225, PMID:27532257, PMID:28492532, PMID:28600387 NCBI chr20:34,633,157...34,642,904
Ensembl chr20:34,633,157...34,642,904
JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:24033266, PMID:25741868, PMID:28492532, PMID:30311386 NCBI chr 4:6,559,153...6,799,888
Ensembl chr 4:6,559,545...6,799,632
JBrowse link
G Rbm20 RNA binding motif protein 20 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:22004663, PMID:24033266, PMID:24503780, PMID:25637381, PMID:25741868, PMID:27896284, PMID:28492532 NCBI chr 1:274,391,932...274,589,816
Ensembl chr 1:274,391,932...274,589,816
JBrowse link
G Ryr2 ryanodine receptor 2 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:12354768, PMID:12820704, PMID:15466642, PMID:15840476, PMID:16540748, PMID:17161064, PMID:17210839, PMID:18071069, PMID:18452873, PMID:19412328, PMID:20403459, PMID:20875080, PMID:22378279, PMID:22581653, PMID:23008441, PMID:23098067, PMID:24033266, PMID:24653702, PMID:25741868, PMID:26209461, PMID:26467025, PMID:26749013, PMID:27287068, PMID:28265756, PMID:28492532, PMID:28781330, PMID:29032884 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
G Slmap sarcolemma associated protein ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar NCBI chr16:2,112,271...2,227,336
Ensembl chr16:2,112,274...2,227,309
JBrowse link
G Sod1 superoxide dismutase 1 ISO RGD PMID:15843790 RGD:1581221 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Tnf tumor necrosis factor IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:9806674, PMID:18679114 RGD:4889454 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 treatment IEP
ISO
ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:28492532, PMID:26010685 RGD:12791997 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
G Ttn titin ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:19608031, PMID:24033266, PMID:25741868, PMID:28492532, PMID:30311386 NCBI chr 3:63,565,160...63,837,815 JBrowse link
G Vcl vinculin ISO ClinVar Annotator: match by term: Cardiac arrest ClinVar PMID:25741868, PMID:28492532 NCBI chr15:3,455,211...3,544,738
Ensembl chr15:3,455,211...3,544,702
JBrowse link
Cardiac Edema term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22865611 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Ift122 intraflagellar transport 122 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20493458 NCBI chr 4:147,756,574...147,826,983
Ensembl chr 4:147,756,553...147,826,997
JBrowse link
G Ubiad1 UbiA prenyltransferase domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23533172 NCBI chr 5:165,247,630...165,259,228
Ensembl chr 5:165,247,133...165,259,224
JBrowse link
Cardio-Renal Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr1 hepatitis A virus cellular receptor 1 susceptibility ISO
IEP
protein:increased expression:kidney tubule: RGD PMID:23220287, PMID:22367506 RGD:7245477, RGD:7245950 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
Cor pulmonale term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor ISO RGD PMID:21450080 RGD:6767563 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:20669672 RGD:4143386 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:serum RGD PMID:20669672 RGD:4143386 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
diastolic heart failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1d adrenoceptor alpha 1D ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 3:124,129,558...124,145,566
Ensembl chr 3:124,129,558...124,145,566
JBrowse link
G Akip1 A-kinase interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 1:174,330,628...174,339,494
Ensembl chr 1:174,330,695...174,339,494
JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Ankrd23 ankyrin repeat domain 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 9:43,110,980...43,117,585
Ensembl chr 9:43,112,141...43,116,521
JBrowse link
G Apln apelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210
JBrowse link
G Cdc25b cell division cycle 25B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
JBrowse link
G Col4a1 collagen type IV alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Col6a1 collagen type VI alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561
JBrowse link
G Col8a1 collagen type VIII alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr11:44,877,690...45,006,203
Ensembl chr11:44,877,859...45,007,891
JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr13:83,972,186...83,984,675
Ensembl chr13:83,972,212...83,984,675
JBrowse link
G Cyrib CYFIP related Rac1 interactor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 7:104,514,566...104,641,875
Ensembl chr 7:104,516,391...104,556,419
JBrowse link
G Elk3 ETS transcription factor ELK3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 7:34,086,213...34,149,601
Ensembl chr 7:34,086,220...34,121,694
JBrowse link
G Epn3 epsin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr10:82,220,762...82,231,200
Ensembl chr10:82,220,762...82,229,140
JBrowse link
G Fhl1 four and a half LIM domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr  X:159,112,516...159,172,528
Ensembl chr  X:159,112,880...159,172,524
JBrowse link
G Fibin fin bud initiation factor homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 3:101,545,207...101,547,478
Ensembl chr 3:101,545,208...101,547,478
JBrowse link
G Fxyd3 FXYD domain-containing ion transport regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 1:89,502,561...89,510,146
Ensembl chr 1:89,502,562...89,509,343
JBrowse link
G Hamp hepcidin antimicrobial peptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Kank2 KN motif and ankyrin repeat domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 8:22,792,000...22,821,459
Ensembl chr 8:22,791,995...22,821,397
JBrowse link
G Klf9 Kruppel-like factor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 1:240,908,483...240,933,198
Ensembl chr 1:240,908,483...240,933,198
JBrowse link
G Ms4a6a membrane spanning 4-domains A6A ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 1:227,919,284...227,932,637
Ensembl chr 1:227,919,301...227,932,603
JBrowse link
G Myh6 myosin heavy chain 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Myh7 myosin heavy chain 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Nppa natriuretic peptide A ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr14:83,559,397...83,572,481
Ensembl chr14:83,560,541...83,572,473
JBrowse link
G Plxnd1 plexin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 4:147,854,309...147,894,170
Ensembl chr 4:147,854,309...147,893,992
JBrowse link
G Ptp4a2 protein tyrosine phosphatase 4A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 5:148,035,501...148,060,752
Ensembl chr 5:148,051,126...148,060,339
JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 5:74,248,996...74,368,167
Ensembl chr 5:74,248,996...74,368,186
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Sipa1l1 signal-induced proliferation-associated 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 6:106,052,212...106,163,249
Ensembl chr 6:106,039,991...106,163,302
JBrowse link
G Trdn triadin ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr 1:25,403,390...25,787,664
Ensembl chr 1:25,403,390...25,839,345
JBrowse link
G Wdr45 WD repeat domain 45 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr  X:15,621,249...15,627,159
Ensembl chr  X:15,621,209...15,627,235
JBrowse link
G Zfp532 zinc finger protein 532 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29556499 NCBI chr18:61,257,522...61,368,371
Ensembl chr18:61,258,911...61,368,371
JBrowse link
Neonatal Pulmonary Hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cps1 carbamoyl-phosphate synthase 1 susceptibility ISO ClinVar Annotator: match by term: Pulmonary hypertension, neonatal, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:11407344, PMID:14718356, PMID:15465784, PMID:16708072, PMID:20154341, PMID:21767969 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274
JBrowse link
Paroxysmal Dyspnea term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor ISO RGD PMID:21388992 RGD:5129099 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adrb2 adrenoceptor beta 2 ISO ClinVar Annotator: match by term: Asthma, nocturnal, susceptibility to ClinVar PMID:7706471, PMID:9399946, PMID:9399966, PMID:9522789, PMID:11739457, PMID:14557466, PMID:15500895, PMID:15867853, PMID:16596417, PMID:28492532 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
primary pulmonary hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:9245985, PMID:12700602, PMID:14684682, PMID:15024723, PMID:15879500, PMID:15880681, PMID:16429404, PMID:16470787, PMID:16540754, PMID:16705692, PMID:18159113, PMID:19555857, PMID:20414677, PMID:20501893, PMID:21158752, PMID:22632830, PMID:23298310, PMID:23722869, PMID:24753439, PMID:25741868, PMID:26387786, PMID:27316748, PMID:28492532, PMID:29449337, PMID:32581362 NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335
JBrowse link
G Adora2a adenosine A2a receptor ISS OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344 MouseDO NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension
ClinVar Annotator: match by term: Pulmonary hypertension, primary, dexfenfluramine-associated
ClinVar Annotator: match by term: Pulmonary hypertension, primary, fenfluramine-associated
ClinVar Annotator: match by term: Idiopathic and/or familial pulmonary arterial hypertension
ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1, with hereditary hemorrhagic telangiectasia
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:3291115, PMID:10903931, PMID:10973254, PMID:11015450, PMID:11115378, PMID:11502704, PMID:12045205, PMID:12139571, PMID:12358323, PMID:12446270, PMID:12821254, PMID:14516151, PMID:14583445, PMID:14985116, PMID:15055271, PMID:15059534, PMID:15146475, PMID:15170098, PMID:15358693, PMID:15591269, PMID:15687131, PMID:15775752, PMID:15965979, PMID:16429395, PMID:16429403, PMID:16717148, PMID:16728714, PMID:18159113, PMID:18221724, PMID:18356561, PMID:18364108, PMID:18386374, PMID:18503968, PMID:18792970, PMID:19206171, PMID:19223935, PMID:19324947, PMID:19555857, PMID:19844076, PMID:20002458, PMID:20095988, PMID:20096498, PMID:20496075, PMID:20534176, PMID:21070126, PMID:21228398, PMID:21737554, PMID:21801371, PMID:22632830, PMID:22995991, PMID:23139147, PMID:23298310, PMID:23579436, PMID:23592887, PMID:23675998, PMID:24033266, PMID:24591673, PMID:24853021, PMID:24936649, PMID:25326637, PMID:25429696, PMID:25460361, PMID:25612240, PMID:25688877, PMID:25741868, PMID:25917481, PMID:26387786, PMID:26820968, PMID:27453251, PMID:27630060, PMID:27884767, PMID:28388887, PMID:28492532, PMID:28507310, PMID:29631995, PMID:29650961, PMID:29743074, PMID:29843651, PMID:30029678, PMID:30311386, PMID:30578397, PMID:32581362 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Cav1 caveolin 1 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Eng endoglin ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:18498373, PMID:23298310, PMID:24033266, PMID:25741868, PMID:26167679, PMID:26387786, PMID:28492532, PMID:30029678 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Foxf1 forkhead box F1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:19500772, PMID:19592680, PMID:19812545, PMID:20425831, PMID:22766610, PMID:23034409, PMID:23074687, PMID:23335808, PMID:23505205, PMID:23943206, PMID:24033266, PMID:24842713, PMID:26462560 NCBI chr19:53,012,306...53,016,100
Ensembl chr19:53,012,332...53,016,086
JBrowse link
G Hdac1 histone deacetylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22711276 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac4 histone deacetylase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22711276 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
G Hdac5 histone deacetylase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22711276 NCBI chr10:90,140,183...90,169,853
Ensembl chr10:90,140,183...90,151,042
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein ISO protein:decreased expression:lung, wall of arteriole (human) RGD PMID:20522807 RGD:9686087 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:20018952, PMID:21685056, PMID:23861362, PMID:24068186, PMID:25076992, PMID:28492532 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:23883380 NCBI chr 6:27,154,274...27,190,209
Ensembl chr 6:27,151,612...27,190,132
JBrowse link
G Nop58 NOP58 ribonucleoprotein ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:23579436, PMID:26387786 NCBI chr 9:66,495,881...66,520,521
Ensembl chr 9:66,495,832...66,519,788
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISS OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344 MouseDO NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Smad1 SMAD family member 1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:21898662, PMID:26387786 NCBI chr19:32,182,942...32,248,694
Ensembl chr19:32,188,267...32,248,684
JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:21898662, PMID:24728327, PMID:25502805, PMID:25741868, PMID:26387786, PMID:28492532 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Smad9 SMAD family member 9 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
NCBI chr 2:143,951,725...144,002,025
Ensembl chr 2:144,191,846...144,212,138
Ensembl chr 2:144,191,846...144,212,138
JBrowse link
G Tbx4 T-box transcription factor 4 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:25741868, PMID:31151956 NCBI chr10:73,331,864...73,362,784
Ensembl chr10:73,333,119...73,362,783
JBrowse link
G Tnfsf4 TNF superfamily member 4 ISS OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344 MouseDO NCBI chr13:79,269,973...79,293,775
Ensembl chr13:79,269,973...79,293,778
JBrowse link
G Vip vasoactive intestinal peptide ISS OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344 MouseDO NCBI chr 1:42,169,307...42,177,582
Ensembl chr 1:42,169,501...42,177,582
JBrowse link
Primary Pulmonary Hypertension, 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 ISO ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1, with hereditary hemorrhagic telangiectasia ClinVar
OMIM
PMID:18792970, PMID:21801371, PMID:23298310, PMID:26387786 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
Primary Pulmonary Hypertension, 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad9 SMAD family member 9 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension 2 OMIM
ClinVar
PMID:19211612, PMID:21898662, PMID:21920918, PMID:24033266, PMID:28492532 NCBI chr 2:143,951,725...144,002,025
Ensembl chr 2:144,191,846...144,212,138
Ensembl chr 2:144,191,846...144,212,138
JBrowse link
Primary Pulmonary Hypertension, 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1b bone morphogenetic protein receptor type 1B ISO ClinVar Annotator: match by term: Primary pulmonary hypertension 3 ClinVar PMID:25741868 NCBI chr 2:247,392,195...247,662,026
Ensembl chr 2:247,403,920...247,446,882
JBrowse link
G Cav1 caveolin 1 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension 3
ClinVar Annotator: match by OMIM:615343
OMIM
ClinVar
PMID:22474227, PMID:25741868, PMID:26387786, PMID:28492532, PMID:29231014 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
Primary Pulmonary Hypertension, 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnk3 potassium two pore domain channel subfamily K member 3 ISO ClinVar Annotator: match by term: Primary pulmonary hypertension 4
ClinVar Annotator: match by OMIM:615344
OMIM
ClinVar
PMID:23883380, PMID:25741868, PMID:26387786, PMID:28492532 NCBI chr 6:27,154,274...27,190,209
Ensembl chr 6:27,151,612...27,190,132
JBrowse link
Sudden Cardiac Death term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl3 acyl-CoA synthetase long-chain family member 3 disease_progression ISO RGD PMID:22661490 RGD:13831296 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Adra2b adrenoceptor alpha 2B ISO RGD PMID:12535806 RGD:1559314 NCBI chr 3:119,805,941...119,809,987
Ensembl chr 3:119,805,941...119,809,987
JBrowse link
G Akap9 A-kinase anchoring protein 9 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:23861362, PMID:25741868, PMID:28492532 NCBI chr 4:27,195,346...27,331,582
Ensembl chr 4:27,195,346...27,331,582
JBrowse link
G Ank2 ankyrin 2 ISO ClinVar Annotator: match by term: Sudden cardiac arrest
ClinVar Annotator: match by term: Sudden cardiac death
ClinVar PMID:25741868, PMID:28492532, PMID:12571597 RGD:734572 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Apob apolipoprotein B ISO RGD PMID:17045270 RGD:1601197 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:30311386 NCBI chr16:6,110,294...6,405,022
Ensembl chr16:6,112,150...6,405,117
JBrowse link
G Cep85l centrosomal protein 85-like ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:12639993, PMID:16235537, PMID:17655857, PMID:21167350, PMID:21332051, PMID:22137083, PMID:23861362, PMID:24033266, PMID:25611685, PMID:25741868, PMID:26535225, PMID:27532257, PMID:28492532, PMID:28600387 NCBI chr20:34,574,043...34,743,142
Ensembl chr20:34,575,950...34,684,418
JBrowse link
G Dpp6 dipeptidyl peptidase like 6 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar NCBI chr 4:4,021,021...4,943,675
Ensembl chr 4:4,021,008...4,473,307
JBrowse link
G Dsp desmoplakin ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Sudden cardiac death
CTD
ClinVar
PMID:20435227, PMID:25741868 NCBI chr17:27,286,811...27,334,453
Ensembl chr17:27,286,796...27,334,379
JBrowse link
G Dtna dystrobrevin, alpha ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:30311386 NCBI chr18:14,544,725...14,671,514
Ensembl chr18:14,471,213...14,657,332
JBrowse link
G Gja1 gap junction protein, alpha 1 treatment ISO RGD PMID:22093512 RGD:12910124 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:23861362, PMID:27930701, PMID:28492532 NCBI chr 8:122,957,570...122,987,236
Ensembl chr 8:122,954,948...122,987,191
JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:21615589, PMID:23623143, PMID:23861362, PMID:24033266, PMID:24569893, PMID:25145517, PMID:25467552, PMID:25642760, PMID:26467025, PMID:28492532 NCBI chr 8:63,599,907...63,637,327
Ensembl chr 8:63,600,663...63,639,654
JBrowse link
G Il6 interleukin 6 susceptibility ISO RGD PMID:23906927 RGD:12792237 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itgb3 integrin subunit beta 3 ISO associated with arteriosclerosis; DNA:polymorphism:exon RGD PMID:20846430 RGD:5128476 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 ISO ClinVar Annotator: match by term: Sudden cardiac death
ClinVar Annotator: match by term: Sudden cardiac arrest
ClinVar PMID:18508782, PMID:19716085, PMID:22581653, PMID:25417810, PMID:25741868, PMID:26704558 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kng2 kininogen 2 susceptibility ISO DNA:SNPs: : RGD PMID:19716087 RGD:10411885 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Lmna lamin A/C ISO CTD Direct Evidence: marker/mechanism CTD PMID:15996213 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Mybpc3 myosin binding protein C3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20435227 NCBI chr 3:79,940,509...79,958,731
Ensembl chr 3:79,940,561...79,958,730
JBrowse link
G Myh6 myosin heavy chain 6 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:15998695, PMID:20215591, PMID:22194935, PMID:22361390, PMID:23299917, PMID:23861362, PMID:24033266, PMID:24119082, PMID:25741868, PMID:27194543, PMID:28088328, PMID:28492532 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Myh7 myosin heavy chain 7 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:25741868 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Myom1 myomesin 1 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:24033266, PMID:28492532 NCBI chr 9:119,353,840...119,469,196
Ensembl chr 9:119,353,840...119,468,715
JBrowse link
G Nebl nebulette ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar NCBI chr17:84,141,014...84,247,038
Ensembl chr17:84,140,489...84,488,601
JBrowse link
G Pkp2 plakophilin 2 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:25741868, PMID:27532257, PMID:28492532, PMID:30311386 NCBI chr11:88,912,163...88,972,213 JBrowse link
G Pln phospholamban ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:12639993, PMID:16235537, PMID:17655857, PMID:21167350, PMID:21332051, PMID:22137083, PMID:23861362, PMID:24033266, PMID:25611685, PMID:25741868, PMID:26535225, PMID:27532257, PMID:28492532, PMID:28600387 NCBI chr20:34,633,157...34,642,904
Ensembl chr20:34,633,157...34,642,904
JBrowse link
G Prdm16 PR/SET domain 16 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:30311386 NCBI chr 5:171,662,277...171,711,561
Ensembl chr 5:171,662,277...171,710,316
JBrowse link
G Ryr2 ryanodine receptor 2 ISO ClinVar Annotator: match by term: Sudden cardiac death
ClinVar Annotator: match by term: Sudden cardiac arrest
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:23861362, PMID:24033266, PMID:25650408, PMID:25741868, PMID:26656175, PMID:27054166, PMID:27930701, PMID:28492532, PMID:31913406 NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar NCBI chr 8:44,136,413...44,159,011
Ensembl chr 8:44,136,496...44,159,010
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO ClinVar Annotator: match by term: Sudden cardiac death
ClinVar Annotator: match by term: Sudden cardiac arrest
ClinVar PMID:15851227, PMID:16712702, PMID:18378609, PMID:18508782, PMID:19564561, PMID:19841300, PMID:20129283, PMID:22581653, PMID:22984773, PMID:23631430, PMID:23671135, PMID:23861362, PMID:24033266, PMID:24055113, PMID:25741868, PMID:25904541, PMID:28492532, PMID:30254039 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
G Sp4 Sp4 transcription factor ISO RGD PMID:11007485 RGD:1580019 NCBI chr 6:146,135,877...146,201,344
Ensembl chr 6:146,135,877...146,195,819
JBrowse link
G Tmem43 transmembrane protein 43 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Sudden cardiac arrest
CTD
ClinVar
PMID:20435227, PMID:23861362, PMID:24033266, PMID:25741868, PMID:28492532 NCBI chr 4:123,118,468...123,133,610
Ensembl chr 4:123,118,468...123,133,609
JBrowse link
G Tnni3 troponin I3, cardiac type ISO ClinVar Annotator: match by term: Sudden cardiac arrest ClinVar PMID:21839045, PMID:25741868 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
JBrowse link
G Tnnt2 troponin T2, cardiac type ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Sudden cardiac death
CTD
ClinVar
PMID:17556660, PMID:23233322, PMID:24033266, PMID:24503780, PMID:25741868, PMID:28492532 NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 ISO ClinVar Annotator: match by term: Sudden cardiac death ClinVar PMID:24019741, PMID:28492532 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
G Ttn titin ISO ClinVar Annotator: match by term: Sudden cardiac arrest
ClinVar Annotator: match by term: Sudden cardiac death
ClinVar PMID:19608031, PMID:24033266, PMID:25741868, PMID:26467025, PMID:28492532, PMID:30311386 NCBI chr 3:63,565,160...63,837,815 JBrowse link
Sudden Cardiac Failure, Infantile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppa2 inorganic pyrophosphatase 2 ISO ClinVar Annotator: match by term: Sudden cardiac failure, infantile ClinVar
OMIM
PMID:25741868, PMID:27523597, PMID:27523598, PMID:28492532, PMID:30384889 NCBI chr 2:238,528,978...238,606,903
Ensembl chr 2:238,529,074...238,606,905
JBrowse link
systolic heart failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd1 ankyrin repeat domain 1 ISO ClinVar Annotator: match by term: Heart failure, systolic ClinVar PMID:19525294, PMID:23299917, PMID:23861362, PMID:24033266, PMID:25741868, PMID:28492532 NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548
JBrowse link
G Bmp10 bone morphogenetic protein 10 ISO CTD Direct Evidence: therapeutic CTD PMID:31712309 NCBI chr 4:119,224,906...119,230,534
Ensembl chr 4:119,225,040...119,230,728
JBrowse link
G Dsp desmoplakin ISO ClinVar Annotator: match by term: Systolic heart failure ClinVar PMID:23861362, PMID:24033266, PMID:25741868, PMID:28492532 NCBI chr17:27,286,811...27,334,453
Ensembl chr17:27,286,796...27,334,379
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A disease_progression ISO protein:increased expression:serum: RGD PMID:23564583 RGD:7257646 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Nppb natriuretic peptide B ISO associated with Renal Insufficiency;protein:increased expression:plasma: RGD PMID:23725445, PMID:23122795 RGD:7246908, RGD:7247627 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Ttn titin ISO ClinVar Annotator: match by term: Heart failure, systolic ClinVar PMID:23861362, PMID:24033266, PMID:25163546, PMID:25741868, PMID:26467025, PMID:28492532 NCBI chr 3:63,565,160...63,837,815 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16108
    disease of anatomical entity 15356
      cardiovascular system disease 4484
        heart disease 2667
          congestive heart failure 385
            Cardiac Edema 3
            Cardio-Renal Syndrome 1
            Cor pulmonale + 25
            Paroxysmal Dyspnea 2
            cardiac arrest + 59
            diastolic heart failure 33
            rheumatic congestive heart failure 0
            systolic heart failure 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.