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Term:acquired immunodeficiency syndrome
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Accession:DOID:635 term browser browse the term
Definition:An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.
Synonyms:exact_synonym: AIDS;   Acquired Immune Deficiency Syndrome;   Acquired Immuno Deficiency Syndrome;   Acquired Immuno-Deficiency Syndromes;   Acquired Immunodeficiency Syndromes;   Immunologic Deficiency Syndrome, Acquired;   acquired Immune deficiency
 narrow_synonym: Acquired Immunodeficiency Syndrome, Slow Progression To;   acquired immunodeficiency syndrome, delayed progression to;   acquired immunodeficiency syndrome, rapid progression to
 primary_id: MESH:D000163;   RDO:0004714
For additional species annotation, visit the Alliance of Genome Resources.


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acquired immunodeficiency syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl11 C-C motif chemokine ligand 11 JBrowse link 10 69,434,965 69,439,566 RGD:13592920
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:13592920
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:13592920
G Ccl4 C-C motif chemokine ligand 4 JBrowse link 10 70,870,926 70,886,357 RGD:5683896
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:8554872
G Cd209 CD209 molecule JBrowse link 12 2,406,879 2,413,324 RGD:13592920
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:11344976
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:13592920
G Cxcl12 C-X-C motif chemokine ligand 12 JBrowse link 4 149,261,044 149,273,891 RGD:13592920
G Cxcr1 C-X-C motif chemokine receptor 1 JBrowse link 9 81,466,430 81,469,299 RGD:8554872
RGD:13592920
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 80,293,574 80,307,334 RGD:5688740
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:11554173
RGD:8554872
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:5509969
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:13592920
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:11554173
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:8554872
RGD:13592920
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:13592920
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:12904035
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link 4 157,864,905 157,877,634 RGD:12904035
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link 5 163,136,390 163,167,299 RGD:12904035
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:1331525
AIDS Dementia Complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:11554173
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:10395393
G Gc GC, vitamin D binding protein JBrowse link 14 20,267,023 20,302,577 RGD:5509882
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1626641
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:10403033
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:10403033
G Npy neuropeptide Y JBrowse link 4 79,557,856 79,565,059 RGD:10431910
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:11554173
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:6482787
AIDS-Associated Nephropathy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agtr1a angiotensin II receptor, type 1a JBrowse link 17 35,907,102 35,958,136 RGD:1303381
G Agtr2 angiotensin II receptor, type 2 JBrowse link X 119,389,480 119,393,845 RGD:1303381
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:6906909
G Hp haptoglobin JBrowse link 19 42,096,255 42,100,805 RGD:11041816
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:7245474
G Myh9 myosin, heavy chain 9 JBrowse link 7 118,740,005 118,792,507 RGD:6903274
G Notch4 notch 4 JBrowse link 20 4,329,794 4,353,868 RGD:6480788
AIDS-Related Kaposi Sarcoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:11554173
AIDS-Related Opportunistic Infections term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd4 Cd4 molecule JBrowse link 4 157,381,862 157,408,357 RGD:11554173

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14759
    syndrome 4210
      acquired immunodeficiency syndrome 39
        AIDS Arteritis, Central Nervous System 0
        AIDS Dementia Complex 9
        AIDS-Associated Nephropathy 7
        AIDS-Related Complex 0
        AIDS-Related Opportunistic Infections + 2
Path 2
Term Annotations click to browse term
  disease 14759
    disease of anatomical entity 13978
      Urogenital Diseases 3755
        Female Urogenital Diseases and Pregnancy Complications 1530
          Female Urogenital Diseases 1281
            female reproductive system disease 1277
              Sexually Transmitted Diseases 175
                Viral Sexually Transmitted Diseases 170
                  human immunodeficiency virus infectious disease 165
                    acquired immunodeficiency syndrome 39
                      AIDS Arteritis, Central Nervous System 0
                      AIDS Dementia Complex 9
                      AIDS-Associated Nephropathy 7
                      AIDS-Related Complex 0
                      AIDS-Related Opportunistic Infections + 2
paths to the root