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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:migraine
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Accession:DOID:6364 term browser browse the term
Definition:A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
Synonyms:exact_synonym: MA;   MFTS;   MGAU;   abdominal migraine;   abdominal migraines;   acute confusional migraine;   acute confusional migraines;   cervical migraine syndrome;   cervical migraine syndromes;   hemicrania migraine;   hemicrania migraines;   migraine disorder;   migraine disorders;   migraine headache;   migraine headaches;   migraine variant;   migraine variants;   migraine with or without aura;   migraines;   sick headache;   sick headaches;   status migrainosus
 related_synonym: MGR1;   MGR11;   MGR12;   MGR2;   MGR3;   MGR5;   MGR8;   migraine with or without aura, susceptibility to, 1;   migraine with or without aura, susceptibility to, 11;   migraine with or without aura, susceptibility to, 12;   migraine with or without aura, susceptibility to, 2;   migraine with or without aura, susceptibility to, 3;   migraine with or without aura, susceptibility to, 5;   migraine with or without aura, susceptibility to, 8;   migraine, resistance to
 primary_id: MESH:D008881
 alt_id: OMIM:157300;   OMIM:300125;   OMIM:607498;   OMIM:607508;   OMIM:609570;   OMIM:610209;   OMIM:611706
 xref: ICD10CM:G43;   ICD9CM:346;   NCI:C89715;   OMIM:PS157300
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
migraine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:30311386 NCBI chr 1:172,271,709...172,298,064
Ensembl chr 1:172,271,709...172,298,064
JBrowse link
G Atrip ATR interacting protein ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:30311386 NCBI chr 9:109,059,747...109,074,124
Ensembl chr 9:109,057,933...109,074,124
JBrowse link
G Atrip-trex1 Atrip-Trex1 readthrough ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:30311386 NCBI chr 9:109,057,933...109,074,097
Ensembl chr 9:109,057,933...109,074,124
JBrowse link
G Brca2 breast cancer 2, early onset ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:15070707, PMID:16030099, PMID:16758124, PMID:17020472, PMID:18783588, PMID:20104584, PMID:20960228, PMID:21232165, PMID:21553119, PMID:21918853, PMID:22430266, PMID:22460208, PMID:22923021, PMID:23479189, PMID:24033266, PMID:25741868, PMID:26026974, PMID:26295337, PMID:26350514, PMID:26467025, PMID:28127413, PMID:28492532, PMID:28503720, PMID:29084914, PMID:29560538 NCBI chr 5:150,522,297...150,570,147
Ensembl chr 5:150,522,630...150,570,329
JBrowse link
G Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit ISO DNA:missense mutation:cds:p.E1015K(human)
ClinVar Annotator: match by term: Migraine
ClinVar PMID:1564484, PMID:3358708, PMID:8898206, PMID:8988170, PMID:9005860, PMID:9302278, PMID:9403487, PMID:9436730, PMID:9559993, PMID:9879686, PMID:11179022, PMID:11564488, PMID:11723274, PMID:12707077, PMID:14718690, PMID:15300451, PMID:15483044, PMID:15710862, PMID:16043807, PMID:16325861, PMID:16595610, PMID:17142831, PMID:17495624, PMID:17575281, PMID:18498393, PMID:18541804, PMID:18940563, PMID:19484318, PMID:19811514, PMID:20097664, PMID:20129625, PMID:20156848, PMID:20204399, PMID:20233618, PMID:20682717, PMID:21183743, PMID:22249839, PMID:23441182, PMID:23771276, PMID:23831250, PMID:23934111, PMID:25735478, PMID:25741868, PMID:25758715, PMID:26814174, PMID:27476654, PMID:28007337, PMID:28492532, PMID:28742085, PMID:29056246, PMID:29100083, PMID:30283815, PMID:30311386, PMID:24108129 RGD:10054426 NCBI chr 8:84,338,631...84,640,251
Ensembl chr 8:84,338,639...84,640,246
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha no_association ISO CTD Direct Evidence: marker/mechanism CTD PMID:12574409, PMID:17635592, PMID:21195698, PMID:20959432 RGD:5684017, RGD:5684020 NCBI chr 7:114,625,981...114,636,910
Ensembl chr 7:114,631,478...114,636,357
JBrowse link
G Capn3 calpain 3 ISO ClinVar Annotator: match by term: Migraine headaches ClinVar PMID:7720071, PMID:9266733, PMID:10330340, PMID:10679950, PMID:14578192, PMID:14981715, PMID:15351423, PMID:15689361, PMID:15725583, PMID:16100770, PMID:16141003, PMID:16650086, PMID:17318636, PMID:20635405, PMID:21204801, PMID:21984748, PMID:25741868, PMID:26467025, PMID:27142102, PMID:28492532, PMID:30311386 NCBI chr 2:120,463,593...120,504,919
Ensembl chr 2:120,463,572...120,504,918
Ensembl chr 2:120,463,572...120,504,918
JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:serum RGD PMID:21331754 RGD:5490597 NCBI chr  X:57,212,143...57,224,042
Ensembl chr  X:57,212,143...57,224,042
JBrowse link
G Clcn1 chloride channel, voltage-sensitive 1 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:8533761, PMID:8845168, PMID:10737121, PMID:12163078, PMID:25741868, PMID:25749817, PMID:26467025, PMID:28492532, PMID:29606556, PMID:30311386 NCBI chr 6:42,284,851...42,315,764
Ensembl chr 6:42,286,685...42,315,756
JBrowse link
G Dsp desmoplakin ISO ClinVar Annotator: match by term: Migraine Disorders ClinVar PMID:21606396, PMID:23292937, PMID:23861362, PMID:24033266, PMID:24503780, PMID:25741868, PMID:26230511, PMID:26656175, PMID:27153395, PMID:28492532, PMID:30311386 NCBI chr13:38,151,294...38,198,577
Ensembl chr13:38,151,294...38,198,577
JBrowse link
G Ednra endothelin receptor type A susceptibility ISO DNA:polymorphism:-231A>G
ClinVar Annotator: match by term: Migraine, resistance to
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:11376172, PMID:23058564, PMID:11376172 RGD:734916 NCBI chr 8:77,663,029...77,724,452
Ensembl chr 8:77,663,031...77,724,464
JBrowse link
G Esr1 estrogen receptor 1 (alpha) susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
OMIM
PMID:15133719 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G Fhl5 four and a half LIM domains 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23793025 NCBI chr 4:25,199,907...25,242,852
Ensembl chr 4:25,199,908...25,242,876
JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12482207 NCBI chr14:74,640,874...74,706,859
Ensembl chr14:74,640,840...74,709,494
JBrowse link
G Htr7 5-hydroxytryptamine (serotonin) receptor 7 ISO RGD PMID:20236348 RGD:6482182 NCBI chr19:35,958,415...36,058,133
Ensembl chr19:35,958,734...36,057,507
JBrowse link
G Lrp1 low density lipoprotein receptor-related protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21666692 NCBI chr10:127,538,157...127,621,148
Ensembl chr10:127,538,161...127,621,148
JBrowse link
G Maoa monoamine oxidase A no_association ISO RGD PMID:15088153 RGD:1600725 NCBI chr  X:16,619,698...16,687,812
Ensembl chr  X:16,619,698...16,687,818
JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:25741868 NCBI chr10:81,105,913...81,124,697
Ensembl chr10:81,105,915...81,133,975
JBrowse link
G Mfn1 mitofusin 1 ISO protein:decreased expression:trigeminal ganglion (rat) RGD PMID:27984195 RGD:12910755 NCBI chr 3:32,529,443...32,579,225
Ensembl chr 3:32,529,465...32,579,239
JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO DNA:SNP:cds:677C>T(human) RGD PMID:21635773 RGD:7387244 NCBI chr 4:148,039,077...148,059,562
Ensembl chr 4:148,039,077...148,059,551
JBrowse link
G Nf2 neurofibromin 2 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:25741868, PMID:28492532, PMID:30311386 NCBI chr11:4,757,639...4,849,544
Ensembl chr11:4,765,845...4,849,536
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell ISO associated with Glaucoma;DNA:snp, haplotype:promoter:g.-786T>C (human) RGD PMID:16123422 RGD:7771539 NCBI chr 5:24,364,816...24,384,474
Ensembl chr 5:24,364,810...24,384,474
JBrowse link
G Notch3 notch 3 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:25741868, PMID:30311386 NCBI chr17:32,120,820...32,166,896
Ensembl chr17:32,120,820...32,166,852
JBrowse link
G Nppb natriuretic peptide type B ISO protein:increased expression:serum RGD PMID:22165670 RGD:5685652 NCBI chr 4:147,985,786...147,987,205
Ensembl chr 4:147,985,788...147,987,205
JBrowse link
G Pnkd paroxysmal nonkinesiogenic dyskinesia ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:30311386 NCBI chr 1:74,284,599...74,353,692
Ensembl chr 1:74,284,930...74,353,694
JBrowse link
G Ppox protoporphyrinogen oxidase ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:25741868 NCBI chr 1:171,276,991...171,281,193
Ensembl chr 1:171,275,990...171,281,186
JBrowse link
G Prdm16 PR domain containing 16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21666692 NCBI chr 4:154,316,122...154,637,360
Ensembl chr 4:154,316,125...154,636,873
JBrowse link
G Scn5a sodium channel, voltage-gated, type V, alpha ISO ClinVar Annotator: match by term: Migraine Disorders ClinVar PMID:11804990, PMID:19056759, PMID:22581653, PMID:24033266, PMID:25741868, PMID:28492532, PMID:30311386 NCBI chr 9:119,483,404...119,579,030
Ensembl chr 9:119,483,408...119,579,016
JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:25741868, PMID:30311386 NCBI chr 4:119,108,745...119,137,330
Ensembl chr 4:119,108,711...119,137,983
JBrowse link
G Stim1 stromal interaction molecule 1 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:25741868 NCBI chr 7:102,261,514...102,437,319
Ensembl chr 7:102,267,806...102,437,319
JBrowse link
G Sugct succinyl-CoA glutarate-CoA transferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23793025 NCBI chr13:16,857,472...17,694,795
Ensembl chr13:16,857,472...17,695,553
JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:25741868 NCBI chr10:7,905,648...7,956,255
Ensembl chr10:7,905,653...7,956,230
JBrowse link
G Tbc1d24 TBC1 domain family, member 24 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:28492532, PMID:30311386 NCBI chr17:24,175,431...24,205,562
Ensembl chr17:24,175,431...24,205,562
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II ISO CTD Direct Evidence: marker/mechanism CTD PMID:16885183 NCBI chr 9:116,087,695...116,175,363
Ensembl chr 9:116,084,293...116,175,360
JBrowse link
G Tnf tumor necrosis factor susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
OMIM
NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Trex1 three prime repair exonuclease 1 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:30311386 NCBI chr 9:109,057,932...109,059,723
Ensembl chr 9:109,057,933...109,059,734
JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21666692 NCBI chr 1:88,306,735...88,388,853
Ensembl chr 1:88,277,661...88,389,293
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 ISO DNA:snp:intron:g.IVS2+2841C>T rs222741 (human) RGD PMID:22162417 RGD:7175557 NCBI chr11:73,234,149...73,261,322
Ensembl chr11:73,234,292...73,261,242
JBrowse link
Familial Basilar Migraine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide ISO ClinVar Annotator: match by null ClinVar PMID:16344534 NCBI chr 1:172,271,709...172,298,064
Ensembl chr 1:172,271,709...172,298,064
JBrowse link
familial hemiplegic migraine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide ISO
IEA
ClinVar Annotator: match by term: Familial hemiplegic migraine
OMIM:141500 | OMIM:602481 | OMIM:609634
ClinVar
MouseDO
PMID:1361034, PMID:11439943, PMID:12023326, PMID:14667076, PMID:15159495, PMID:15174025, PMID:15286158, PMID:16088919, PMID:16344534, PMID:16538223, PMID:17473835, PMID:17877748, PMID:17952365, PMID:18056581, PMID:18414213, PMID:18513263, PMID:18728015, PMID:18957371, PMID:19458722, PMID:19874388, PMID:20837964, PMID:21352219, PMID:21533730, PMID:22117059, PMID:23918834, PMID:23954377, PMID:24396618, PMID:24921013, PMID:25138102, PMID:25741868, PMID:26467025, PMID:27226003, PMID:27864847, PMID:28492532, PMID:28811059, PMID:29062094, PMID:29655203, PMID:29778030, PMID:29956301, PMID:30311386 NCBI chr 1:172,271,709...172,298,064
Ensembl chr 1:172,271,709...172,298,064
JBrowse link
G Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit IEA OMIM:141500 | OMIM:300125 | OMIM:602481 | OMIM:607516 | OMIM:609634 MouseDO NCBI chr 8:84,338,631...84,640,251
Ensembl chr 8:84,338,639...84,640,246
JBrowse link
G Igsf8 immunoglobulin superfamily, member 8 ISO ClinVar Annotator: match by term: Familial hemiplegic migraine ClinVar PMID:28492532 NCBI chr 1:172,312,367...172,319,843
Ensembl chr 1:172,261,641...172,319,841
JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 ISO ClinVar Annotator: match by term: Familial hemiplegic migraine ClinVar PMID:28492532 NCBI chr 1:172,341,210...172,374,085
Ensembl chr 1:172,341,210...172,374,085
JBrowse link
G Kcnj9 potassium inwardly-rectifying channel, subfamily J, member 9 ISO ClinVar Annotator: match by term: Familial hemiplegic migraine ClinVar PMID:28492532 NCBI chr 1:172,320,508...172,329,322
Ensembl chr 1:172,320,501...172,329,318
JBrowse link
G Scn1a sodium channel, voltage-gated, type I, alpha ISO ClinVar Annotator: match by term: Familial hemiplegic migraine ClinVar PMID:25741868, PMID:28492532 NCBI chr 2:66,270,781...66,440,837
Ensembl chr 2:66,270,778...66,440,840
JBrowse link
familial hemiplegic migraine 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit ISO ClinVar Annotator: match by OMIM:141500
ClinVar Annotator: match by term: Familial hemiplegic migraine type 1
ClinVar Annotator: match by term: Migraine, sporadic hemiplegic, with progressive cerebellar ataxia
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:1564484, PMID:3358708, PMID:7537420, PMID:8734765, PMID:8898206, PMID:8988170, PMID:9005860, PMID:9302278, PMID:9403487, PMID:9436730, PMID:9488686, PMID:9559993, PMID:9879686, PMID:9915947, PMID:10024348, PMID:10408532, PMID:10408534, PMID:10734061, PMID:10987655, PMID:11061267, PMID:11176968, PMID:11179022, PMID:11409427, PMID:11439943, PMID:11564488, PMID:11723274, PMID:11814735, PMID:11960817, PMID:11971066, PMID:11985388, PMID:12056940, PMID:12111613, PMID:12707077, PMID:12756131, PMID:14718690, PMID:15032980, PMID:15240985, PMID:15300451, PMID:15452324, PMID:15483044, PMID:15710862, PMID:15795222, PMID:16043807, PMID:16325861, PMID:16595610, PMID:16866717, PMID:17142831, PMID:17495624, PMID:17575281, PMID:18056581, PMID:18313928, PMID:18400034, PMID:18498393, PMID:18541804, PMID:18644040, PMID:18940563, PMID:19484318, PMID:19586927, PMID:19811514, PMID:20097664, PMID:20129625, PMID:20156848, PMID:20204399, PMID:20233618, PMID:20682717, PMID:21183743, PMID:22000314, PMID:22190617, PMID:22249839, PMID:22527033, PMID:22784462, PMID:22969264, PMID:23441182, PMID:23771276, PMID:23831250, PMID:23934111, PMID:23961289, PMID:24270521, PMID:24486772, PMID:24498617, PMID:24849341, PMID:25266619, PMID:25274239, PMID:25326635, PMID:25735478, PMID:25741868, PMID:25758715, PMID:25969684, PMID:26467025, PMID:26814174, PMID:27066515, PMID:27290639, PMID:27476654, PMID:28007337, PMID:28169007, PMID:28492532, PMID:28742085, PMID:28978442, PMID:29056246, PMID:29100083, PMID:30063100, PMID:30283815, PMID:30311386, PMID:97053792 NCBI chr 8:84,338,631...84,640,251
Ensembl chr 8:84,338,639...84,640,246
JBrowse link
familial hemiplegic migraine 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide ISO ClinVar Annotator: match by OMIM:602481
ClinVar Annotator: match by term: Familial hemiplegic migraine type 2
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:9579893, PMID:12539047, PMID:12953268, PMID:15133718, PMID:15159495, PMID:15174025, PMID:15308625, PMID:15459825, PMID:16037212, PMID:16088919, PMID:17435187, PMID:17473835, PMID:17877748, PMID:17952365, PMID:18056581, PMID:18414213, PMID:18728015, PMID:18957371, PMID:20720542, PMID:21533730, PMID:22117059, PMID:23954377, PMID:25138102, PMID:25326635, PMID:25741868, PMID:26467025, PMID:28492532, PMID:30311386 NCBI chr 1:172,271,709...172,298,064
Ensembl chr 1:172,271,709...172,298,064
JBrowse link
familial hemiplegic migraine 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn1a sodium channel, voltage-gated, type I, alpha ISO ClinVar Annotator: match by term: Familial hemiplegic migraine type 3
ClinVar Annotator: match by OMIM:609634
OMIM
ClinVar
PMID:1893099, PMID:11254444, PMID:11254445, PMID:11359211, PMID:11940708, PMID:12083760, PMID:12566275, PMID:12610651, PMID:12821740, PMID:14504318, PMID:14738421, PMID:15277634, PMID:16054936, PMID:16458823, PMID:17054684, PMID:17347258, PMID:18021921, PMID:18056581, PMID:18076640, PMID:18413471, PMID:18414213, PMID:18804930, PMID:18930999, PMID:19200853, PMID:19236456, PMID:19332696, PMID:19359143, PMID:19522081, PMID:19589774, PMID:20522430, PMID:20600615, PMID:20729507, PMID:20879882, PMID:21248271, PMID:21396429, PMID:21713554, PMID:21719429, PMID:22011963, PMID:22050978, PMID:22071555, PMID:22150645, PMID:22409937, PMID:22550089, PMID:22612257, PMID:22780858, PMID:23195492, PMID:23398611, PMID:23884151, PMID:23895530, PMID:23934111, PMID:24066114, PMID:24136861, PMID:24168886, PMID:24337656, PMID:24464349, PMID:25243660, PMID:25326635, PMID:25348405, PMID:25401298, PMID:25741868, PMID:26096185, PMID:26169758, PMID:26467025, PMID:26544041, PMID:26699486, PMID:26845707, PMID:26990884, PMID:27231140, PMID:27236449, PMID:27864847, PMID:28079314, PMID:28148630, PMID:28202706, PMID:28492532, PMID:29100083, PMID:29358611, PMID:29852413, PMID:30311386, PMID:30619928, PMID:31791873, PMID:32581362 NCBI chr 2:66,270,781...66,440,837
Ensembl chr 2:66,270,778...66,440,840
JBrowse link
migraine with aura term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide ISO RGD PMID:12953268 RGD:1358436 NCBI chr 1:172,271,709...172,298,064
Ensembl chr 1:172,271,709...172,298,064
JBrowse link
G Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit ISO DNA:mutation:cds:P.V1457L(human) RGD PMID:10408532 RGD:10054422 NCBI chr 8:84,338,631...84,640,251
Ensembl chr 8:84,338,639...84,640,246
JBrowse link
G Dbh dopamine beta hydroxylase ISO DNA:insertion, deletion:5' utr:g.-4767+?--4688-? (human) RGD PMID:17095019 RGD:1625569 NCBI chr 2:27,165,507...27,183,204
Ensembl chr 2:27,165,233...27,183,200
JBrowse link
G Drd2 dopamine receptor D2 ISO DNA:snp:cds:p.H313H (human) RGD PMID:9513185 RGD:1358603 NCBI chr 9:49,340,360...49,408,177
Ensembl chr 9:49,340,627...49,408,177
JBrowse link
G Kcnk18 potassium channel, subfamily K, member 18 susceptibility ISO ClinVar Annotator: match by term: MIGRAINE WITH OR WITHOUT AURA, SUSCEPTIBILITY TO, 13
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:20871611, PMID:25741868, PMID:28492532 NCBI chr19:59,219,648...59,237,370
Ensembl chr19:59,219,214...59,237,374
JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO DNA:SNP:cds:677C>T(human) RGD PMID:21635773 RGD:7387244 NCBI chr 4:148,039,077...148,059,562
Ensembl chr 4:148,039,077...148,059,551
JBrowse link
G Notch3 notch 3 ISO ClinVar Annotator: match by term: Migraine with aura ClinVar PMID:30311386, PMID:32581362 NCBI chr17:32,120,820...32,166,896
Ensembl chr17:32,120,820...32,166,852
JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 ISO DNA:snp:intron:g.36670T>C rs7217270 (human) RGD PMID:22162417 RGD:7175557 NCBI chr11:73,267,489...73,300,368
Ensembl chr11:73,267,388...73,300,363
JBrowse link
migraine without aura term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Astn2 astrotactin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22683712 NCBI chr 4:65,380,803...66,404,537
Ensembl chr 4:65,380,803...66,404,611
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:11304026, PMID:14659530 NCBI chr 7:114,625,981...114,636,910
Ensembl chr 7:114,631,478...114,636,357
JBrowse link
G Eno2 enolase 2, gamma neuronal ISO protein:increased expression:serum RGD PMID:21293918 RGD:5508769 NCBI chr 6:124,760,053...124,769,673
Ensembl chr 6:124,760,053...124,769,673
JBrowse link
G Ldlr low density lipoprotein receptor ISO DNA:repeat:exon (human) RGD PMID:12873747 RGD:5490245 NCBI chr 9:21,723,576...21,749,919
Ensembl chr 9:21,723,483...21,749,919
JBrowse link
G Lrp1 low density lipoprotein receptor-related protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22683712 NCBI chr10:127,538,157...127,621,148
Ensembl chr10:127,538,161...127,621,148
JBrowse link
G Mef2d myocyte enhancer factor 2D ISO CTD Direct Evidence: marker/mechanism CTD PMID:22683712 NCBI chr 3:88,141,941...88,172,091
Ensembl chr 3:88,142,372...88,172,086
JBrowse link
G Notch3 notch 3 ISO ClinVar Annotator: match by term: Migraine without aura ClinVar PMID:8878478, PMID:9388399, PMID:12754354, PMID:15229130, PMID:15287509, PMID:15857853, PMID:20071773, PMID:21940951, PMID:24425116, PMID:24886907, PMID:25412914, PMID:25741868, PMID:26467025, PMID:28334938, PMID:32581362 NCBI chr17:32,120,820...32,166,896
Ensembl chr17:32,120,820...32,166,852
JBrowse link
G Phactr1 phosphatase and actin regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22683712 NCBI chr13:42,680,374...43,138,526
Ensembl chr13:42,680,623...43,138,526
JBrowse link
G S100b S100 protein, beta polypeptide, neural ISO protein:increased expression:serum RGD PMID:21293918 RGD:5508769 NCBI chr10:76,253,836...76,261,319
Ensembl chr10:76,253,853...76,261,159
JBrowse link
G Tac1 tachykinin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11304026 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:14718719 RGD:1580316 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22683712 NCBI chr 1:88,306,735...88,388,853
Ensembl chr 1:88,277,661...88,389,293
JBrowse link
Sensorineural Deafness and Migraine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G mt-Tq tRNA glutamine, mitochondrial ISO ClinVar Annotator: match by term: Sensorineural deafness and migraine ClinVar PMID:11424923, PMID:25741868, PMID:31965079 NCBI chr MT:3,772...3,842
Ensembl chr MT:3,772...3,842
JBrowse link
Sporadic Hemiplegic Migraine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit ISO ClinVar Annotator: match by term: Migraine, sporadic hemiplegic ClinVar PMID:10408534, PMID:10734061, PMID:11176968, PMID:11439943, PMID:12056940, PMID:12707077, PMID:17142831, PMID:18056581, PMID:22527033, PMID:24486772, PMID:24498617, PMID:25969684, PMID:26467025 NCBI chr 8:84,338,631...84,640,251
Ensembl chr 8:84,338,639...84,640,246
JBrowse link
Stormorken syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stim1 stromal interaction molecule 1 ISO ClinVar Annotator: match by term: Stormorken syndrome OMIM
ClinVar
PMID:4085141, PMID:12623447, PMID:12745453, PMID:12944247, PMID:12944248, PMID:22190180, PMID:23332920, PMID:24492416, PMID:24570283, PMID:24591628, PMID:24619930, PMID:25044882, PMID:25326555, PMID:25577287, PMID:25741868, PMID:25918394, PMID:26184105, PMID:26436962, PMID:27066587, PMID:27239559, PMID:28492532, PMID:28624464, PMID:29237733 NCBI chr 7:102,261,514...102,437,319
Ensembl chr 7:102,267,806...102,437,319
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13395
    disease of anatomical entity 12871
      nervous system disease 10430
        central nervous system disease 8793
          brain disease 8131
            Headache Disorders 54
              Primary Headache Disorders 54
                migraine 54
                  Alice in Wonderland Syndrome 0
                  Familial Basilar Migraine 1
                  Ophthalmoplegic Migraine 0
                  Sensorineural Deafness and Migraine 1
                  Stormorken syndrome 1
                  migraine with aura + 12
                  migraine without aura + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.