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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:migraine
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Accession:DOID:6364 term browser browse the term
Definition:A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
Synonyms:exact_synonym: MA;   MFTS;   MGAU;   abdominal migraine;   abdominal migraines;   acute confusional migraine;   acute confusional migraines;   cervical migraine syndrome;   cervical migraine syndromes;   hemicrania migraine;   hemicrania migraines;   migraine disorder;   migraine disorders;   migraine headache;   migraine headaches;   migraine variant;   migraine variants;   migraine with or without aura;   migraines;   sick headache;   sick headaches;   status migrainosus
 related_synonym: MGR1;   MGR11;   MGR12;   MGR2;   MGR3;   MGR5;   MGR8;   migraine with or without aura, susceptibility to, 1;   migraine with or without aura, susceptibility to, 11;   migraine with or without aura, susceptibility to, 12;   migraine with or without aura, susceptibility to, 2;   migraine with or without aura, susceptibility to, 3;   migraine with or without aura, susceptibility to, 5;   migraine with or without aura, susceptibility to, 8;   migraine, resistance to
 primary_id: MESH:D008881
 alt_id: OMIM:157300;   OMIM:300125;   OMIM:607498;   OMIM:607508;   OMIM:609570;   OMIM:610209;   OMIM:611706
 xref: ICD10CM:G43;   ICD9CM:346;   NCI:C89715;   OMIM:PS157300
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
migraine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:30311386 NCBI chr 4:90,341,316...90,371,040
Ensembl chr 4:90,291,344...90,396,160
JBrowse link
G ATRIP ATR interacting protein ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:30311386 NCBI chr13:31,159,849...31,178,716
Ensembl chr13:31,159,843...31,179,098
JBrowse link
G BRCA2 BRCA2 DNA repair associated ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:15070707, PMID:16030099, PMID:16758124, PMID:17020472, PMID:18783588, PMID:20104584, PMID:20960228, PMID:21232165, PMID:21553119, PMID:21918853, PMID:22430266, PMID:22460208, PMID:22923021, PMID:23479189, PMID:24033266, PMID:25741868, PMID:26026974, PMID:26295337, PMID:26350514, PMID:26467025, PMID:28127413, PMID:28492532, PMID:28503720, PMID:29084914, PMID:29560538 NCBI chr11:8,805,950...8,858,128 JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO DNA:missense mutation:cds:p.E1015K(human)
ClinVar Annotator: match by term: Migraine
RGD
ClinVar
PMID:1564484, PMID:3358708, PMID:8898206, PMID:8988170, PMID:9005860, PMID:9302278, PMID:9403487, PMID:9436730, PMID:9559993, PMID:9879686, PMID:11179022, PMID:11564488, PMID:11723274, PMID:12707077, PMID:14718690, PMID:15300451, PMID:15483044, PMID:15710862, PMID:16043807, PMID:16325861, PMID:16595610, PMID:17142831, PMID:17495624, PMID:17575281, PMID:18498393, PMID:18541804, PMID:18940563, PMID:19484318, PMID:19811514, PMID:20097664, PMID:20129625, PMID:20156848, PMID:20204399, PMID:20233618, PMID:20682717, PMID:21183743, PMID:22249839, PMID:23441182, PMID:23771276, PMID:23831250, PMID:23934111, PMID:24108129, PMID:25735478, PMID:25741868, PMID:25758715, PMID:26814174, PMID:27476654, PMID:28007337, PMID:28492532, PMID:28742085, PMID:29056246, PMID:29100083, PMID:30283815, PMID:30311386 RGD:10054426 NCBI chr 2:65,491,784...65,871,068 JBrowse link
G CALCB calcitonin-related polypeptide beta no_association ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:12574409, PMID:17635592, PMID:20959432, PMID:21195698 RGD:5684017, RGD:5684020 NCBI chr 2:44,043,135...44,048,651 JBrowse link
G CAPN3 calpain 3 ISO ClinVar Annotator: match by term: Migraine headaches ClinVar PMID:7720071, PMID:9266733, PMID:10330340, PMID:10679950, PMID:14578192, PMID:14981715, PMID:15351423, PMID:15689361, PMID:15725583, PMID:16100770, PMID:16141003, PMID:16650086, PMID:17318636, PMID:20635405, PMID:21204801, PMID:21984748, PMID:25741868, PMID:26467025, PMID:27142102, PMID:28492532, PMID:30311386 NCBI chr 1:128,960,117...129,013,508
Ensembl chr 1:128,960,121...129,013,547
JBrowse link
G CD40LG CD40 ligand ISO protein:increased expression:serum RGD PMID:21331754 RGD:5490597 NCBI chr  X:111,778,666...111,788,901
Ensembl chr  X:111,778,493...111,789,711
JBrowse link
G CLCN1 chloride voltage-gated channel 1 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:8533761, PMID:8845168, PMID:10737121, PMID:12163078, PMID:25741868, PMID:25749817, PMID:26467025, PMID:28492532, PMID:29606556, PMID:30311386 NCBI chr18:6,902,540...6,941,530
Ensembl chr18:6,902,542...6,966,092
JBrowse link
G DSP desmoplakin ISO ClinVar Annotator: match by term: Migraine Disorders ClinVar PMID:21606396, PMID:23292937, PMID:23861362, PMID:24033266, PMID:24503780, PMID:25741868, PMID:26230511, PMID:26656175, PMID:27153395, PMID:28492532, PMID:30311386 NCBI chr 7:4,862,649...4,915,626
Ensembl chr 7:4,862,649...4,915,615
JBrowse link
G EDNRA endothelin receptor type A susceptibility ISO ClinVar Annotator: match by term: Migraine, resistance to
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:minus-231A>G
OMIM
ClinVar
CTD
RGD
PMID:11376172, PMID:23058564 RGD:734916 NCBI chr 8:81,210,750...81,279,053
Ensembl chr 8:81,209,327...81,276,853
JBrowse link
G ESR1 estrogen receptor 1 susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
PMID:15133719 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363
JBrowse link
G FHL5 four and a half LIM domains 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23793025 NCBI chr 1:63,705,864...63,754,079
Ensembl chr 1:63,705,936...63,754,067
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12482207 NCBI chr11:20,555,939...20,620,225
Ensembl chr11:20,555,961...20,619,629
JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO RGD PMID:20236348 RGD:6482182 NCBI chr14:102,443,312...102,548,894
Ensembl chr14:102,444,566...102,548,931
JBrowse link
G LRP1 LDL receptor related protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21666692 NCBI chr 5:22,435,636...22,519,276 JBrowse link
G MAOA monoamine oxidase A no_association ISO RGD PMID:15088153 RGD:1600725 NCBI chr  X:38,930,452...39,006,220 JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:25741868 NCBI chr 2:74,626,739...74,651,352
Ensembl chr 2:74,626,658...74,651,348
JBrowse link
G MFN1 mitofusin 1 ISO protein:decreased expression:trigeminal ganglion (rat) RGD PMID:27984195 RGD:12910755 NCBI chr13:117,404,637...117,441,750
Ensembl chr13:117,404,699...117,442,481
JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility ISO DNA:SNP:cds:677C>T(human) RGD PMID:21635773 RGD:7387244 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,636...71,881,820
JBrowse link
G NF2 neurofibromin 2 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:25741868, PMID:28492532, PMID:30311386 NCBI chr14:46,653,869...46,726,421
Ensembl chr14:46,653,902...46,731,999
JBrowse link
G NOS3 nitric oxide synthase 3 ISO associated with Glaucoma;DNA:snp, haplotype:promoter:g.-786T>C (human) RGD PMID:16123422 RGD:7771539 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,156...6,228,938
JBrowse link
G NOTCH3 notch receptor 3 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:25741868, PMID:30311386 NCBI chr 2:62,364,507...62,402,348
Ensembl chr 2:62,364,501...62,402,344
JBrowse link
G NPPB natriuretic peptide B ISO protein:increased expression:serum RGD PMID:22165670 RGD:5685652 NCBI chr 6:71,930,374...71,931,843
Ensembl chr 6:71,919,495...71,932,254
JBrowse link
G PNKD PNKD metallo-beta-lactamase domain containing ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:30311386 NCBI chr15:120,345,541...120,411,648
Ensembl chr15:120,345,551...120,413,353
JBrowse link
G PPOX protoporphyrinogen oxidase ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:25741868 NCBI chr 4:89,277,984...89,288,946
Ensembl chr 4:89,277,117...89,288,902
JBrowse link
G PRDM16 PR/SET domain 16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21666692 NCBI chr 6:64,704,181...65,012,580
Ensembl chr 6:64,704,468...65,012,575
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 ISO ClinVar Annotator: match by term: Migraine Disorders ClinVar PMID:11804990, PMID:19056759, PMID:22581653, PMID:24033266, PMID:25741868, PMID:28492532, PMID:30311386 NCBI chr13:23,336,143...23,424,755
Ensembl chr13:23,338,124...23,438,385
JBrowse link
G SLC2A1 solute carrier family 2 member 1 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:25741868, PMID:30311386 NCBI chr 6:168,535,398...168,561,170
Ensembl chr 6:168,534,655...168,690,095
JBrowse link
G STIM1 stromal interaction molecule 1 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:25741868 NCBI chr 9:6,066,612...6,270,090
Ensembl chr 9:6,066,617...6,270,575
JBrowse link
G SUGCT succinyl-CoA:glutarate-CoA transferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23793025 NCBI chr18:53,639,588...54,283,272
Ensembl chr18:53,639,593...54,283,251
JBrowse link
G TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:25741868 NCBI chr 1:16,533,364...16,611,879
Ensembl chr 1:16,533,284...16,611,884
JBrowse link
G TBC1D24 TBC1 domain family member 24 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:28492532, PMID:30311386 NCBI chr 3:39,545,688...39,572,320 JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16885183 NCBI chr13:16,784,370...16,875,828
Ensembl chr13:16,784,491...16,878,165
JBrowse link
G TNF tumor necrosis factor susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
G TREX1 three prime repair exonuclease 1 ISO ClinVar Annotator: match by term: Migraine ClinVar PMID:30311386 NCBI chr13:31,177,604...31,180,764
Ensembl chr13:31,178,601...31,180,592
JBrowse link
G TRPM8 transient receptor potential cation channel subfamily M member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21666692 NCBI chr15:134,185,316...134,267,973
Ensembl chr15:134,186,122...134,267,970
JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 ISO DNA:snp:intron:g.IVS2+2841C>T rs222741 (human) RGD PMID:22162417 RGD:7175557 NCBI chr12:49,676,536...49,709,634
Ensembl chr12:49,677,291...49,701,325
JBrowse link
Familial Basilar Migraine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO ClinVar Annotator: match by term: Migraine, familial basilar ClinVar PMID:16344534 NCBI chr 4:90,341,316...90,371,040
Ensembl chr 4:90,291,344...90,396,160
JBrowse link
familial hemiplegic migraine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO ClinVar Annotator: match by term: Familial hemiplegic migraine ClinVar PMID:1361034, PMID:11439943, PMID:12023326, PMID:14667076, PMID:15159495, PMID:15174025, PMID:15286158, PMID:16088919, PMID:16344534, PMID:16538223, PMID:17473835, PMID:17877748, PMID:17952365, PMID:18056581, PMID:18414213, PMID:18513263, PMID:18728015, PMID:18957371, PMID:19458722, PMID:19874388, PMID:20837964, PMID:21352219, PMID:21533730, PMID:22117059, PMID:23918834, PMID:23954377, PMID:24396618, PMID:24921013, PMID:25138102, PMID:25741868, PMID:26467025, PMID:27226003, PMID:27864847, PMID:28492532, PMID:28811059, PMID:29062094, PMID:29655203, PMID:29778030, PMID:29956301, PMID:30311386 NCBI chr 4:90,341,316...90,371,040
Ensembl chr 4:90,291,344...90,396,160
JBrowse link
G IGSF8 immunoglobulin superfamily member 8 ISO ClinVar Annotator: match by term: Familial hemiplegic migraine ClinVar PMID:28492532 NCBI chr 4:90,393,614...90,401,380
Ensembl chr 4:90,370,235...90,401,376
JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 ISO ClinVar Annotator: match by term: Familial hemiplegic migraine ClinVar PMID:28492532 NCBI chr 4:90,421,956...90,457,406
Ensembl chr 4:90,422,025...90,457,407
JBrowse link
G KCNJ9 potassium inwardly rectifying channel subfamily J member 9 ISO ClinVar Annotator: match by term: Familial hemiplegic migraine ClinVar PMID:28492532 NCBI chr 4:90,402,042...90,412,426
Ensembl chr 4:90,397,850...90,430,160
JBrowse link
G SCN1A sodium voltage-gated channel alpha subunit 1 ISO ClinVar Annotator: match by term: Familial hemiplegic migraine ClinVar PMID:25741868, PMID:28492532 NCBI chr15:72,529,866...72,696,715
Ensembl chr15:72,529,875...72,678,067
JBrowse link
familial hemiplegic migraine 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO OMIM NCBI chr 2:65,491,784...65,871,068 JBrowse link
familial hemiplegic migraine 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO OMIM NCBI chr 4:90,341,316...90,371,040
Ensembl chr 4:90,291,344...90,396,160
JBrowse link
familial hemiplegic migraine 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCN1A sodium voltage-gated channel alpha subunit 1 ISO OMIM NCBI chr15:72,529,866...72,696,715
Ensembl chr15:72,529,875...72,678,067
JBrowse link
migraine with aura term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO RGD PMID:12953268 RGD:1358436 NCBI chr 4:90,341,316...90,371,040
Ensembl chr 4:90,291,344...90,396,160
JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO DNA:mutation:cds:P.V1457L(human) RGD PMID:10408532 RGD:10054422 NCBI chr 2:65,491,784...65,871,068 JBrowse link
G DBH dopamine beta-hydroxylase ISO DNA:insertion, deletion:5' utr:g.-4767+?--4688-? (human) RGD PMID:17095019 RGD:1625569 NCBI chr 1:273,204,407...273,225,562
Ensembl chr 1:273,204,400...273,225,558
JBrowse link
G DRD2 dopamine receptor D2 ISO DNA:snp:cds:p.H313H (human) RGD PMID:9513185 RGD:1358603 NCBI chr 9:41,068,618...41,135,262
Ensembl chr 9:41,068,779...41,133,599
JBrowse link
G KCNK18 potassium two pore domain channel subfamily K member 18 susceptibility ISO ClinVar Annotator: match by term: MIGRAINE WITH OR WITHOUT AURA, SUSCEPTIBILITY TO, 13
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:20871611, PMID:25741868, PMID:28492532 NCBI chr14:127,323,291...127,335,320 JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility ISO DNA:SNP:cds:677C>T(human) RGD PMID:21635773 RGD:7387244 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,636...71,881,820
JBrowse link
G NOTCH3 notch receptor 3 ISO ClinVar Annotator: match by term: Migraine with aura ClinVar PMID:30311386, PMID:32581362 NCBI chr 2:62,364,507...62,402,348
Ensembl chr 2:62,364,501...62,402,344
JBrowse link
G TRPV3 transient receptor potential cation channel subfamily V member 3 ISO DNA:snp:intron:g.36670T>C rs7217270 (human) RGD PMID:22162417 RGD:7175557 NCBI chr12:49,638,852...49,671,671
Ensembl chr12:49,635,927...49,671,613
JBrowse link
migraine without aura term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASTN2 astrotactin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22683712 NCBI chr 1:256,825,466...257,740,676
Ensembl chr 1:256,825,486...257,740,977
JBrowse link
G CALCB calcitonin-related polypeptide beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:11304026, PMID:14659530 NCBI chr 2:44,043,135...44,048,651 JBrowse link
G ENO2 enolase 2 ISO protein:increased expression:serum RGD PMID:21293918 RGD:5508769 NCBI chr 5:63,799,927...63,809,067
Ensembl chr 5:63,799,339...63,836,688
JBrowse link
G LDLR low density lipoprotein receptor ISO DNA:repeat:exon (human) RGD PMID:12873747 RGD:5490245 NCBI chr 2:69,828,348...69,864,823
Ensembl chr 2:69,828,332...69,864,823
JBrowse link
G LRP1 LDL receptor related protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22683712 NCBI chr 5:22,435,636...22,519,276 JBrowse link
G MEF2D myocyte enhancer factor 2D ISO CTD Direct Evidence: marker/mechanism CTD PMID:22683712 NCBI chr 4:93,581,563...93,616,980
Ensembl chr 4:93,581,598...93,651,639
JBrowse link
G NOTCH3 notch receptor 3 ISO ClinVar Annotator: match by term: Migraine without aura ClinVar PMID:8878478, PMID:9388399, PMID:12754354, PMID:15229130, PMID:15287509, PMID:15857853, PMID:20071773, PMID:21940951, PMID:24425116, PMID:24886907, PMID:25412914, PMID:25741868, PMID:26467025, PMID:28334938, PMID:32581362 NCBI chr 2:62,364,507...62,402,348
Ensembl chr 2:62,364,501...62,402,344
JBrowse link
G PHACTR1 phosphatase and actin regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22683712 NCBI chr 7:9,105,422...9,666,886
Ensembl chr 7:9,105,802...9,675,230
JBrowse link
G S100B S100 calcium binding protein B ISO protein:increased expression:serum RGD PMID:21293918 RGD:5508769
G TAC1 tachykinin precursor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11304026 NCBI chr 9:77,197,403...77,206,529
Ensembl chr 9:77,197,535...77,206,526
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:14718719 RGD:1580316 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
G TRPM8 transient receptor potential cation channel subfamily M member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22683712 NCBI chr15:134,185,316...134,267,973
Ensembl chr15:134,186,122...134,267,970
JBrowse link
Sporadic Hemiplegic Migraine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO ClinVar Annotator: match by term: Migraine, sporadic hemiplegic ClinVar PMID:10408534, PMID:10734061, PMID:11176968, PMID:11439943, PMID:12056940, PMID:12707077, PMID:17142831, PMID:18056581, PMID:22527033, PMID:24486772, PMID:24498617, PMID:25969684, PMID:26467025 NCBI chr 2:65,491,784...65,871,068 JBrowse link
Stormorken syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STIM1 stromal interaction molecule 1 ISO OMIM NCBI chr 9:6,066,612...6,270,090
Ensembl chr 9:6,066,617...6,270,575
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12618
    disease of anatomical entity 12151
      nervous system disease 9917
        central nervous system disease 8392
          brain disease 7764
            Headache Disorders 52
              Primary Headache Disorders 52
                migraine 52
                  Alice in Wonderland Syndrome 0
                  Familial Basilar Migraine 1
                  Ophthalmoplegic Migraine 0
                  Sensorineural Deafness and Migraine 0
                  Stormorken syndrome 1
                  migraine with aura + 12
                  migraine without aura + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.