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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:acute disseminated encephalomyelitis
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Accession:DOID:639 term browser browse the term
Definition:An encephalomyelitis characterized by inflammation located in brain and located in spinal cord that damages myelin. It usually occurs after viral infection, but also following vaccination, bacterial or parasitic infection. (DO)
Synonyms:exact_synonym: ADEM;   acute disseminated encephalitis;   acute disseminated encephalomyelitides;   postexanthem encephalomyelitis;   postinfectious encephalomyelitis
 primary_id: MESH:D004673
 xref: GARD:8639;   NCI:C34578
For additional species annotation, visit the Alliance of Genome Resources.


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acute disseminated encephalomyelitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma disease_progression ISO protein:increased expression:T cell: RGD PMID:11063842 RGD:8157598 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO DNA:polymorphism (human)
DNA:polymorphism, haplotype: :
RGD PMID:19722042, PMID:22786832 RGD:5147662, RGD:36049763 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO DNA:polymorphisms (human)
DNA:polymorphism, haplotype: :
RGD PMID:19722042, PMID:22786832 RGD:5147662, RGD:36049763 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16023
    disease by infectious agent 1774
      viral infectious disease 1466
        acute disseminated encephalomyelitis 3
          acute hemorrhagic leukoencephalitis 0
          post-vaccinal encephalitis 0
Path 2
Term Annotations click to browse term
  disease 16023
    disease of anatomical entity 15278
      Immune & Inflammatory Diseases 3513
        immune system disease 2927
          primary immunodeficiency disease 2344
            autoimmune disease 1663
              autoimmune disease of the nervous system 415
                autoimmune disease of central nervous system 331
                  Demyelinating Autoimmune Diseases, CNS 331
                    acute disseminated encephalomyelitis 3
                      acute hemorrhagic leukoencephalitis 0
                      post-vaccinal encephalitis 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.