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ONTOLOGY REPORT - ANNOTATIONS


Term:T-cell leukemia
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Accession:DOID:715 term browser browse the term
Definition:A malignant disease of the T-LYMPHOCYTES in the bone marrow, thymus, and/or blood.
Synonyms:exact_synonym: T Lymphocytic Leukemia;   T Lymphocytic Leukemias;   T-Cell Leukemias;   T-Cell Lymphocytic Leukemia;   T-Cell Lymphocytic Leukemias
 primary_id: MESH:D015458;   RDO:0001546
For additional species annotation, visit the Alliance of Genome Resources.


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T-cell leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:11251741
G Cdkn2a_v1 cyclin-dependent kinase inhibitor 2A, variant 1 RGD:11251741
G Cdkn2a_v2 cyclin-dependent kinase inhibitor 2A, variant 2 RGD:11251741
G Hmga1 high mobility group AT-hook 1 JBrowse link 20 7,132,501 7,140,155 RGD:13592920
G Lmo1 LIM domain only 1 JBrowse link 1 173,728,183 173,764,288 RGD:11554173
G Lmo2 LIM domain only 2 JBrowse link 3 93,909,156 93,931,888 RGD:11554173
G Notch1 notch 1 JBrowse link 3 3,905,562 3,951,015 RGD:11554173
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:11554173
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:11554173
G Tcl1a T-cell leukemia/lymphoma 1A JBrowse link 6 128,888,768 128,894,761 RGD:1599360
acute T cell leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:8554872
G Bcl10 BCL10, immune signaling adaptor JBrowse link 2 251,805,392 251,814,957 RGD:8554872
adult T-cell leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:11554173
G Bmp6 bone morphogenetic protein 6 JBrowse link 17 26,955,142 27,112,820 RGD:11554173
G Card11 caspase recruitment domain family, member 11 JBrowse link 12 15,700,600 15,844,512 RGD:11554173
G Ccr4 C-C motif chemokine receptor 4 JBrowse link 8 122,530,152 122,535,959 RGD:11554173
G Ccr7 C-C motif chemokine receptor 7 JBrowse link 10 87,057,335 87,067,444 RGD:11554173
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:11554173
G Cd80 Cd80 molecule JBrowse link 11 64,815,201 64,855,293 RGD:6902938
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:6902938
G Csnk1a1 casein kinase 1, alpha 1 JBrowse link 18 56,887,722 56,910,610 RGD:11554173
G Csnk2a1 casein kinase 2 alpha 1 JBrowse link 3 147,713,808 147,760,375 RGD:11554173
G Csnk2b casein kinase 2 beta JBrowse link 20 5,108,692 5,113,675 RGD:11554173
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:11554173
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:11049147
RGD:11049453
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:11554173
G Fyn FYN proto-oncogene, Src family tyrosine kinase JBrowse link 20 44,436,354 44,630,316 RGD:11554173
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:11554173
G Gpr183 G protein-coupled receptor 183 JBrowse link 15 108,364,701 108,376,221 RGD:11554173
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 JBrowse link 4 81,237,496 81,241,281 RGD:11554173
G Icos inducible T-cell co-stimulator JBrowse link 9 67,748,157 67,786,808 RGD:11554173
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:10755707
RGD:11554173
G Ikzf2 IKAROS family zinc finger 2 JBrowse link 9 76,621,230 76,771,017 RGD:11554173
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:11049460
RGD:11554173
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:11554173
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:11554173
G Il5 interleukin 5 JBrowse link 10 39,066,716 39,069,587 RGD:11354942
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:11060275
G Irf4 interferon regulatory factor 4 JBrowse link 17 34,886,746 34,905,191 RGD:11554173
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:11531131
G Myb MYB proto-oncogene, transcription factor JBrowse link 1 16,658,178 16,690,135 RGD:11532670
G Notch1 notch 1 JBrowse link 3 3,905,562 3,951,015 RGD:1580759
G Nras NRAS proto-oncogene, GTPase JBrowse link 2 205,553,119 205,563,716 RGD:11535055
G Plcg1 phospholipase C, gamma 1 JBrowse link 3 156,727,642 156,758,307 RGD:11554173
G Prkcb protein kinase C, beta JBrowse link 1 192,233,569 192,575,339 RGD:11554173
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:11554173
G Tal2 TAL bHLH transcription factor 2 JBrowse link 5 70,592,871 70,599,428 RGD:1599285
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:11554173
G Tlx1 T-cell leukemia, homeobox 1 JBrowse link 1 264,893,033 264,899,424 RGD:1599439
RGD:11554173
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1331525
G Tp73 tumor protein p73 JBrowse link 5 171,355,876 171,415,354 RGD:11554173
G Vav1 vav guanine nucleotide exchange factor 1 JBrowse link 9 9,617,551 9,675,167 RGD:11554173
B- and T-cell mixed leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dot1l DOT1 like histone lysine methyltransferase JBrowse link 7 11,786,105 11,824,742 RGD:9588291
G Kmt2a lysine methyltransferase 2A JBrowse link 8 49,110,407 49,185,872 RGD:7240710
G Rnf20 ring finger protein 20 JBrowse link 5 64,892,996 64,920,397 RGD:9831405
Prolymphocytic Leukemia, T-Cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:8554872
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:11531125
G RGD1311251 similar to RIKEN cDNA 4930550C14 JBrowse link 8 57,983,168 58,012,474 RGD:8554872
T-cell adult acute lymphocytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cntn2 contactin 2 JBrowse link 13 49,280,913 49,314,061 RGD:13592920
G Zeb2 zinc finger E-box binding homeobox 2 JBrowse link 3 29,857,289 29,985,932 RGD:13592920
T-cell large granular lymphocyte leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Stat5b signal transducer and activator of transcription 5B JBrowse link 10 88,686,207 88,712,313 RGD:11554173

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14759
    disease of anatomical entity 13978
      hematopoietic system disease 1355
        leukocyte disease 433
          T-cell leukemia 58
            B- and T-cell mixed leukemia 3
            N syndrome 0
            Prolymphocytic Leukemia, T-Cell 3
            T-cell adult acute lymphocytic leukemia 2
            T-cell large granular lymphocyte leukemia 1
            acute T cell leukemia 2
            adult T-cell leukemia 40
Path 2
Term Annotations click to browse term
  disease 14759
    disease of anatomical entity 13978
      Hemic and Lymphatic Diseases 1573
        hematopoietic system disease 1355
          Hematologic Neoplasms 767
            hematologic cancer 766
              leukemia 557
                lymphocytic leukemia 269
                  T-cell leukemia 58
                    B- and T-cell mixed leukemia 3
                    N syndrome 0
                    Prolymphocytic Leukemia, T-Cell 3
                    T-cell adult acute lymphocytic leukemia 2
                    T-cell large granular lymphocyte leukemia 1
                    acute T cell leukemia 2
                    adult T-cell leukemia 40
paths to the root