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ONTOLOGY REPORT - ANNOTATIONS


Term:peptic ulcer disease
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Accession:DOID:750 term browser browse the term
Definition:Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
Synonyms:exact_synonym: Gastroduodenal Ulcer;   Gastroduodenal Ulcers;   Marginal Ulcer;   Marginal Ulcers;   Peptic Ulcers;   acute peptic ulcer with hemorrhage;   acute peptic ulcer with hemorrhage and perforation;   acute peptic ulcer without hemorrhage and without perforation;   peptic ulcer
 related_synonym: PHOSPHOLIPASE A2, GROUP IV A, DEFICIENCY OF
 primary_id: MESH:D010437;   RDO:0000896
For additional species annotation, visit the Alliance of Genome Resources.


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peptic ulcer disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:2314640
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:11554173
G Gast gastrin JBrowse link 10 88,245,532 88,248,485 RGD:11554173
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:10401900
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:4145283
G Hpgd 15-hydroxyprostaglandin dehydrogenase JBrowse link 16 37,457,134 37,495,758 RGD:11667098
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:11554173
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:8554872
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:5147609
duodenal ulcer term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase JBrowse link 3 4,374,679 4,394,374 RGD:11554173
G Aco1 aconitase 1 JBrowse link 5 56,425,076 56,481,218 RGD:11541091
G Cftr cystic fibrosis transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:1599596
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:8694318
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:11554173
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:11554173
G Psca prostate stem cell antigen JBrowse link 7 116,090,189 116,091,955 RGD:11554173
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:11554173
G Slc11a2 solute carrier family 11 member 2 JBrowse link 7 142,025,812 142,062,892 RGD:11541091
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:8694318
G Tfrc transferrin receptor JBrowse link 11 71,397,423 71,419,263 RGD:11541091
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:11554173
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:7483560
gastric ulcer term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adm adrenomedullin JBrowse link 1 175,443,189 175,447,260 RGD:11554173
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:11039418
G Angpt1 angiopoietin 1 JBrowse link 7 81,338,327 81,592,459 RGD:1601496
G Angpt2 angiopoietin 2 JBrowse link 16 75,966,480 76,016,147 RGD:1601496
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:10053695
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:10053695
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:10053695
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:13792597
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:5130860
RGD:11554173
G Cblif cobalamin binding intrinsic factor JBrowse link 1 228,118,048 228,132,296 RGD:11049581
G Cck cholecystokinin JBrowse link 8 130,120,525 130,127,515 RGD:11554173
G Cftr cystic fibrosis transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:11567229
G Col18a1 collagen type XVIII alpha 1 chain JBrowse link 20 12,225,202 12,332,858 RGD:1600910
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:11554173
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:11554173
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:708325
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:13792597
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:13792597
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:8655642
G Foxo4 forkhead box O4 JBrowse link X 71,155,284 71,162,158 RGD:10402364
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:11554173
G Hrh3 histamine receptor H3 JBrowse link 3 175,474,310 175,479,395 RGD:1626428
G Iapp islet amyloid polypeptide JBrowse link 4 176,509,863 176,517,903 RGD:11554173
G Idua iduronidase, alpha-L- JBrowse link 14 2,041,828 2,056,762 RGD:12910841
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:11554173
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:11554173
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:13800896
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:13800896
G Mmp13 matrix metallopeptidase 13 JBrowse link 8 5,522,739 5,533,018 RGD:10043177
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:10043177
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:10043177
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:1642033
RGD:11554173
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming JBrowse link 1 214,725,482 214,756,653 RGD:2324968
RGD:7364759
G Muc6 mucin 6, oligomeric mucus/gel-forming JBrowse link 1 214,608,453 214,630,524 RGD:7364759
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:11554173
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:11554173
RGD:13446410
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:11554173
G Oxt oxytocin/neurophysin 1 prepropeptide JBrowse link 3 123,106,694 123,107,534 RGD:2304192
G Oxtr oxytocin receptor JBrowse link 4 144,399,326 144,417,598 RGD:2304192
G Ptger1 prostaglandin E receptor 1 JBrowse link 19 24,799,422 24,803,373 RGD:10043357
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:11554173
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:2300260
RGD:11554173
G Sst somatostatin JBrowse link 11 80,358,172 80,359,449 RGD:2303186
G Tek TEK receptor tyrosine kinase JBrowse link 5 113,725,717 113,852,799 RGD:1601496
G Tff1 trefoil factor 1 JBrowse link 20 9,892,124 9,895,984 RGD:2292012
G Timp1 TIMP metallopeptidase inhibitor 1 JBrowse link X 1,364,771 1,369,451 RGD:10043177
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:11554173
G Vgf VGF nerve growth factor inducible JBrowse link 12 22,677,302 22,680,630 RGD:11554173
peptic esophagitis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:8699511
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:2307110
G Cldn3 claudin 3 JBrowse link 12 21,831,341 21,832,813 RGD:11344880
G Cldn4 claudin 4 JBrowse link 12 24,761,210 24,763,008 RGD:2317602
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:10395244
G F11r F11 receptor JBrowse link 13 89,826,272 89,850,151 RGD:7488941
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:2307110
G Il5 interleukin 5 JBrowse link 10 39,066,716 39,069,587 RGD:2307110
G Psmb9 proteasome subunit beta 9 JBrowse link 20 3,973,424 3,978,845 RGD:9854630
G Ptges prostaglandin E synthase JBrowse link 3 9,727,408 9,738,752 RGD:2300085
G Tjp1 tight junction protein 1 JBrowse link 1 126,146,489 126,515,359 RGD:2325133
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1580209
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:11055189
Zollinger-Ellison syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:2325683
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:2317668
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:7242847

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14759
    disease of anatomical entity 13978
      gastrointestinal system disease 4240
        stomach disease 504
          peptic ulcer disease 79
            Gastrocutaneous Syndrome 0
            Zollinger-Ellison syndrome 3
            active peptic ulcer disease 0
            duodenal ulcer + 13
            gastric ulcer 49
            gastroduodenitis 0
            gastrojejunal ulcer 0
            peptic esophagitis + 13
            peptic ulcer perforation 0
Path 2
Term Annotations click to browse term
  disease 14759
    disease of anatomical entity 13978
      gastrointestinal system disease 4240
        Gastrointestinal Diseases 2343
          intestinal disease 1302
            duodenum disease 85
              peptic ulcer disease 79
                Gastrocutaneous Syndrome 0
                Zollinger-Ellison syndrome 3
                active peptic ulcer disease 0
                duodenal ulcer + 13
                gastric ulcer 49
                gastroduodenitis 0
                gastrojejunal ulcer 0
                peptic esophagitis + 13
                peptic ulcer perforation 0
paths to the root