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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:peptic ulcer disease
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Accession:DOID:750 term browser browse the term
Definition:Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
Synonyms:exact_synonym: Gastroduodenal Ulcer;   Gastroduodenal Ulcers;   Marginal Ulcer;   Marginal Ulcers;   Peptic Ulcers;   acute peptic ulcer with hemorrhage;   acute peptic ulcer with hemorrhage and perforation;   acute peptic ulcer without hemorrhage and without perforation;   peptic ulcer
 related_synonym: PHOSPHOLIPASE A2, GROUP IV A, DEFICIENCY OF
 primary_id: MESH:D010437;   RDO:0000896
 xref: ICD10CM:K27;   ICD9CM:533;   NCI:C3318
For additional species annotation, visit the Alliance of Genome Resources.


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peptic ulcer disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnr1 cannabinoid receptor 1 IDA RGD PMID:19827302 RGD:2314640 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Edn1 endothelin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16384872 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Gast gastrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:10700044 NCBI chr10:88,245,532...88,248,485
Ensembl chr10:88,245,532...88,248,484
JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP RGD PMID:24480520 RGD:10401900 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hmox1 heme oxygenase 1 IMP RGD PMID:20610858 RGD:4145283 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase treatment IEP RGD PMID:23884819 RGD:11667098 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:19448967 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il33 interleukin 33 susceptibility ISO associated with Helicobacter Infections;DNA:SNP: : rs1929992(human) RGD PMID:31491552 RGD:39938849 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO associated with Helicobacter Infections;DNA:polymorphisms:cds:HLA-DRB1*07, HLA-DRB1*17 (human) RGD PMID:20405713 RGD:5147609 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
duodenal ulcer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22387998 NCBI chr 3:4,374,679...4,394,374
Ensembl chr 3:4,374,602...4,394,428
JBrowse link
G Aco1 aconitase 1 IDA protein:increased activity:duodenal mucosa RGD PMID:19342511 RGD:11541091 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Cftr CF transmembrane conductance regulator IDA RGD PMID:15905414 RGD:1599596 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Egr1 early growth response 1 ISO RGD PMID:24385009 RGD:8694318 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12481160, PMID:17045617 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Pla2g4a phospholipase A2 group IVA ISO CTD Direct Evidence: marker/mechanism CTD PMID:18451993 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Psca prostate stem cell antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:22387998 NCBI chr 7:116,090,189...116,091,955
Ensembl chr 7:116,090,189...116,091,955
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12481160 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Slc11a2 solute carrier family 11 member 2 IEP mRNA, protein:increased expression:duodenal mucosa RGD PMID:19342511 RGD:11541091 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Stat3 signal transducer and activator of transcription 3 IMP RGD PMID:24385009 RGD:8694318 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tfrc transferrin receptor IEP protein:increased expression:duodenal mucosa RGD PMID:19342511 RGD:11541091 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO CTD Direct Evidence: therapeutic CTD PMID:12868675 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Vegfa vascular endothelial growth factor A IEP associated with Candidiasis;protein:decreased expression:Duodenum: RGD PMID:18622701 RGD:7483560 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
gastric ulcer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin ISO CTD Direct Evidence: therapeutic CTD PMID:9845272 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Agt angiotensinogen treatment IDA RGD PMID:24231511 RGD:11039418 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Angpt1 angiopoietin 1 IEP protein:increased expression:stomach RGD PMID:12768384 RGD:1601496 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Angpt2 angiopoietin 2 IEP protein:increased expression:stomach (rat) RGD PMID:12768384 RGD:1601496 NCBI chr16:75,966,480...76,016,147
Ensembl chr16:75,966,352...76,016,195
JBrowse link
G Bad BCL2-associated agonist of cell death treatment IDA RGD PMID:24378970 RGD:10053695 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IDA RGD PMID:24378970 RGD:10053695 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 treatment IDA RGD PMID:24378970 RGD:10053695 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:29339218 RGD:13792597 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase IEP
ISO
protein:increased expression:stomach
CTD Direct Evidence: therapeutic
CTD PMID:1887894, PMID:17895592 RGD:5130860 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cblif cobalamin binding intrinsic factor ISO associated with Polycythemia; mRNA:decreased expression:gastric mucosa: RGD PMID:26485402 RGD:11049581 NCBI chr 1:228,118,048...228,132,296
Ensembl chr 1:228,118,048...228,132,404
JBrowse link
G Cck cholecystokinin ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:9872509, PMID:10422768, PMID:10458643, PMID:11025360, PMID:11787760, PMID:15024038 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Cftr CF transmembrane conductance regulator treatment IDA RGD PMID:23596793 RGD:11567229 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain IEP Protein:decreased expression:serum RGD PMID:11353854 RGD:1600910 NCBI chr20:12,225,202...12,332,858
Ensembl chr20:12,225,202...12,332,858
JBrowse link
G Egf epidermal growth factor ISO CTD Direct Evidence: therapeutic CTD PMID:9324159, PMID:9479624 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: therapeutic CTD PMID:20723003 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G F13a1 coagulation factor XIII A1 chain IEP RGD PMID:11435721 RGD:708325 NCBI chr17:28,504,650...28,680,015
Ensembl chr17:28,504,623...28,680,362
JBrowse link
G Fas Fas cell surface death receptor treatment IEP RGD PMID:29339218 RGD:13792597 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand treatment IEP RGD PMID:29339218 RGD:13792597 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fgf2 fibroblast growth factor 2 treatment ISO RGD PMID:9127818 RGD:8655642 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Foxo4 forkhead box O4 IEP mRNA,protein:increased expression:gastric mucosa: RGD PMID:22735908 RGD:10402364 NCBI chr  X:71,155,284...71,162,158
Ensembl chr  X:71,155,601...71,162,158
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:15177919, PMID:16259727 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Hrh3 histamine receptor H3 IDA RGD PMID:15680274 RGD:1626428 NCBI chr 3:175,474,310...175,479,395
Ensembl chr 3:175,473,078...175,479,395
JBrowse link
G Iapp islet amyloid polypeptide ISO CTD Direct Evidence: therapeutic CTD PMID:9286623 NCBI chr 4:176,509,863...176,517,903
Ensembl chr 4:176,510,696...176,516,083
JBrowse link
G Idua alpha-L-iduronidase IEP RGD PMID:3713687 RGD:12910841 NCBI chr14:2,041,828...2,056,762
Ensembl chr14:2,042,411...2,056,762
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:11376495 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il23a interleukin 23 subunit alpha treatment ISO RGD PMID:23874957 RGD:39458037 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Lep leptin ISO CTD Direct Evidence: therapeutic CTD PMID:10422768, PMID:11025360, PMID:11787760, PMID:15024038, PMID:16015682, PMID:18181030 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Mapk1 mitogen activated protein kinase 1 IDA RGD PMID:25518106 RGD:13800896 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 IDA RGD PMID:25518106 RGD:13800896 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mmp13 matrix metallopeptidase 13 IEP mRNA:increased expression:stomach RGD PMID:15375341 RGD:10043177 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP mRNA:increased expression:stomach RGD PMID:15375341 RGD:10043177 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 IEP mRNA:increased expression:stomach RGD PMID:15375341 RGD:10043177 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP
ISO
protein:increased expression:stomach secretion
CTD Direct Evidence: marker/mechanism
CTD PMID:17603938, PMID:17603938 RGD:1642033 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming treatment IEP
IDA
mRNA, protein:decreased expression:stomach RGD PMID:11956390, PMID:16240224 RGD:2324968, RGD:7364759 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Muc6 mucin 6, oligomeric mucus/gel-forming treatment IDA RGD PMID:16240224 RGD:7364759 NCBI chr 1:214,608,453...214,630,524
Ensembl chr 1:214,608,704...214,629,938
JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12481160, PMID:15138204, PMID:19066340 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:19066340, PMID:29095895 RGD:13446410 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nrg1 neuregulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16357062 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:11764003 RGD:2304192 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G Oxtr oxytocin receptor IMP RGD PMID:11764003 RGD:2304192 NCBI chr 4:144,399,326...144,417,598
Ensembl chr 4:144,403,358...144,416,116
JBrowse link
G Ptger1 prostaglandin E receptor 1 treatment IMP
ISO
RGD PMID:10807413, PMID:10807413 RGD:10043357, RGD:10043357 NCBI chr19:24,799,422...24,803,373
Ensembl chr19:24,800,072...24,803,373
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10594344, PMID:19066340 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:9024292, PMID:10594344, PMID:11376495, PMID:12481160, PMID:19066340, PMID:17673547, PMID:17673547 RGD:2300260, RGD:2300260 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Sst somatostatin IEP RGD PMID:17990461 RGD:2303186 NCBI chr11:80,358,172...80,359,449
Ensembl chr11:80,358,211...80,359,444
JBrowse link
G Tek TEK receptor tyrosine kinase IEP protein:increased expression:stomach RGD PMID:12768384 RGD:1601496 NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799
JBrowse link
G Tff1 trefoil factor 1 IEP mRNA, protein:increased expression:stomach mucosa RGD PMID:11350545 RGD:2292012 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 IEP mRNA:increased expression:stomach RGD PMID:15375341 RGD:10043177 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15138204 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:11353854 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vgf VGF nerve growth factor inducible ISO CTD Direct Evidence: therapeutic CTD PMID:20805684 NCBI chr12:22,677,302...22,680,630
Ensembl chr12:22,677,607...22,680,630
JBrowse link
peptic esophagitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IEP protein:increased expression:esophagus: RGD PMID:17570215 RGD:8699511 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP associated with Asthma;mRNA:increased expression:esophagus RGD PMID:18222984 RGD:2307110 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Cldn3 claudin 3 IEP protein:altered expression:epithelial cell, esophagus: RGD PMID:21373849 RGD:11344880 NCBI chr12:21,831,341...21,832,813
Ensembl chr12:21,831,342...21,832,813
JBrowse link
G Cldn4 claudin 4 IEP protein:altered localization:esophagus epithelium, cytoplasm RGD PMID:16143882 RGD:2317602 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Egfr epidermal growth factor receptor IEP mRNA, protein:increased expression:esophagus, basal cell RGD PMID:11966524 RGD:10395244 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G F11r F11 receptor treatment IEP RGD PMID:19478094 RGD:7488941 NCBI chr13:89,826,272...89,850,151
Ensembl chr13:89,826,254...89,850,612
JBrowse link
G Il13 interleukin 13 IEP associated with asthma; mRNA, protein:increased expression:esophagus, Bronchoalveolar Lavage Fluid RGD PMID:18222984 RGD:2307110 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il5 interleukin 5 IEP associated with asthma; mRNA:increased expression:esophagus RGD PMID:18222984 RGD:2307110 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Mir223 microRNA 223 IEP RNA:increased expression: esophagus RGD PMID:28757556 RGD:25824949 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Mir29a microRNA 29a IEP RGD PMID:28757556 RGD:25824949 NCBI chr 4:58,343,931...58,344,018 JBrowse link
G Psmb9 proteasome 20S subunit beta 9 IEP protein:decreased expression:esophageal epithelium (rat) RGD PMID:23942904 RGD:9854630 NCBI chr20:3,973,424...3,978,845
Ensembl chr20:3,973,420...3,978,845
JBrowse link
G Ptges prostaglandin E synthase IEP protein:increased expression:esophagus RGD PMID:16210398 RGD:2300085 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
JBrowse link
G Tjp1 tight junction protein 1 IEP RGD PMID:19653339 RGD:2325133 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tnf tumor necrosis factor IDA RGD PMID:15942680 RGD:1580209 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vdr vitamin D receptor susceptibility ISO DNA:SNPs,haplotype:exon:rs1989969,rs2238135 (human) RGD PMID:25910066 RGD:11055189 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
Zollinger-Ellison syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin ISO protein:decreased expression:serum RGD PMID:908508 RGD:2325683 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Egf epidermal growth factor ISO protein:increased expression:saliva RGD PMID:10811321 RGD:2317668 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Igf1r insulin-like growth factor 1 receptor ISO mRNA and protein: increased expression::poor prognosis for high expression RGD PMID:15867218 RGD:7242847 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16023
    disease of anatomical entity 15278
      gastrointestinal system disease 4632
        stomach disease 545
          peptic ulcer disease 83
            Gastrocutaneous Syndrome 0
            Zollinger-Ellison syndrome 3
            active peptic ulcer disease 0
            duodenal ulcer + 13
            gastric ulcer 50
            gastroduodenitis 0
            gastrojejunal ulcer 0
            peptic esophagitis + 15
            peptic ulcer perforation 0
Path 2
Term Annotations click to browse term
  disease 16023
    disease of anatomical entity 15278
      gastrointestinal system disease 4632
        Gastrointestinal Diseases 2552
          intestinal disease 1514
            duodenum disease 89
              peptic ulcer disease 83
                Gastrocutaneous Syndrome 0
                Zollinger-Ellison syndrome 3
                active peptic ulcer disease 0
                duodenal ulcer + 13
                gastric ulcer 50
                gastroduodenitis 0
                gastrojejunal ulcer 0
                peptic esophagitis + 15
                peptic ulcer perforation 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.