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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:appendicitis
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Accession:DOID:8337 term browser browse the term
Definition:Acute inflammation of the APPENDIX. Acute appendicitis is classified as simple, gangrenous, or perforated.
Synonyms:exact_synonym: Perforated Appendicitis;   Ruptured Appendicitis;   acute appendicitis;   acute appendicitis with generalized peritonitis;   acute appendicitis with peritoneal abscess
 primary_id: MESH:D001064
 alt_id: RDO:0004893
 xref: ICD10CM:K37;   ICD9CM:540-543.99;   NCI:C35145
For additional species annotation, visit the Alliance of Genome Resources.


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appendicitis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2 coagulation factor II ISO RGD PMID:21663567 RGD:5147751 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:16367942 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16367942 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Plau plasminogen activator, urokinase ISO protein:increased expression:appendix RGD PMID:19153874 RGD:6483822 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16035
    disease by infectious agent 1775
      Intraabdominal Infections 34
        appendicitis 4
Path 2
Term Annotations click to browse term
  disease 16035
    disease of anatomical entity 15289
      gastrointestinal system disease 4633
        Gastrointestinal Diseases 2554
          intestinal disease 1515
            cecal disease 10
              appendicitis 4
paths to the root