ONTOLOGY REPORT - ANNOTATIONS


Term:osteoarthritis
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Accession:DOID:8398 term browser browse the term
Definition:A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
Synonyms:exact_synonym: DIPOA;   Degenerative Arthritis;   GOA1;   OA;   OADIP;   OS1;   OS2;   OS3;   OS4;   OS5;   OS6;   OSTEOARTHRITIS OF DISTAL INTERPHALANGEAL JOINTS;   OSTEOARTHRITIS OF KNEE/HIP;   OSTEOARTHRITIS SUSCEPTIBILITY 1;   OSTEOARTHRITIS SUSCEPTIBILITY 2;   OSTEOARTHRITIS SUSCEPTIBILITY 3;   OSTEOARTHRITIS SUSCEPTIBILITY 4;   OSTEOARTHRITIS SUSCEPTIBILITY 5;   OSTEOARTHRITIS SUSCEPTIBILITY 6;   OSTEOARTHRITIS, GENERALIZED, WITHOUT DYSPLASIA;   Osteoarthritides;   Osteoarthroses;   Osteoarthrosis;   Osteoarthrosis and allied disorder;   degenerative arthritides;   degenerative joint disease;   hypertrophic arthritis;   osteoarthrosis deformans
 narrow_synonym: HAND OSTEOARTHRITIS;   HOA HEBERDEN NODES
 primary_id: MESH:D010003
 alt_id: OMIM:140600;   OMIM:165720;   OMIM:607850;   OMIM:610839;   OMIM:612400;   OMIM:612401;   RDO:0001314
For additional species annotation, visit the Alliance of Genome Resources.


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osteoarthritis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acaa2 acetyl-CoA acyltransferase 2 JBrowse link 18 70,733,872 70,762,395 RGD:11554173
G Acan aggrecan JBrowse link 1 140,762,758 140,824,441 RGD:11570535
RGD:11570544
G Aco1 aconitase 1 JBrowse link 5 56,425,076 56,481,218 RGD:11554173
G Actb actin, beta JBrowse link 12 13,715,843 13,718,813 RGD:11554173
G Adam12 ADAM metallopeptidase domain 12 JBrowse link 1 205,951,840 206,286,294 RGD:1625347
G Adam15 ADAM metallopeptidase domain 15 JBrowse link 2 188,661,831 188,672,337 RGD:1559176
G Adamts14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 JBrowse link 20 30,812,319 30,888,936 RGD:6771189
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 JBrowse link 13 89,622,996 89,632,485 RGD:10043110
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 JBrowse link 11 25,411,174 25,456,639 RGD:10043101
RGD:10043110
RGD:2300093
RGD:10003165
RGD:10043107
RGD:10043106
RGD:10043105
RGD:10043103
RGD:10043102
G Adgrg2 adhesion G protein-coupled receptor G2 JBrowse link X 36,930,186 37,054,968 RGD:11554173
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:8695985
RGD:11554173
G Ak4 adenylate kinase 4 JBrowse link 5 120,250,318 120,309,153 RGD:11554173
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:11554173
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 JBrowse link 8 77,640,234 77,719,488 RGD:11554173
G Aspn asporin JBrowse link 17 14,655,958 14,681,355 RGD:7240710
RGD:9684966
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 JBrowse link 1 81,852,423 81,881,565 RGD:11554173
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 JBrowse link 16 22,326,537 22,350,143 RGD:11554173
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:10053643
G Bag6 BCL2-associated athanogene 6 JBrowse link 20 5,124,512 5,138,084 RGD:14390133
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:10053643
RGD:10054095
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:10053643
RGD:10054095
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:6483317
G Bglap bone gamma-carboxyglutamate protein JBrowse link 2 187,741,770 187,748,445 RGD:6483599
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1625347
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:11554173
G Bmp6 bone morphogenetic protein 6 JBrowse link 17 26,955,142 27,112,820 RGD:11554173
G Bmp7 bone morphogenetic protein 7 JBrowse link 3 170,879,972 170,955,820 RGD:13592920
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:13592920
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:11554173
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:13782343
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:13782343
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:10043354
G Ccl22 C-C motif chemokine ligand 22 JBrowse link 19 10,674,189 10,681,145 RGD:10054497
G Ccr4 C-C motif chemokine receptor 4 JBrowse link 8 122,530,152 122,535,959 RGD:10054497
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1625347
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:10043190
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:10401214
G Chi3l1 chitinase 3 like 1 JBrowse link 13 51,022,844 51,030,797 RGD:11554173
G Cilp cartilage intermediate layer protein JBrowse link 8 70,760,922 70,775,891 RGD:1625347
G Clec3b C-type lectin domain family 3, member B JBrowse link 8 132,241,016 132,248,066 RGD:1625347
G Clic1 chloride intracellular channel 1 JBrowse link 20 5,040,314 5,049,166 RGD:11554173
G Clic4 chloride intracellular channel 4 JBrowse link 5 153,568,937 153,625,669 RGD:11554173
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:11554173
G Col11a1 collagen type XI alpha 1 chain JBrowse link 2 216,863,423 217,056,523 RGD:13592920
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:5688331
G Col1a2 collagen type I alpha 2 chain JBrowse link 4 31,534,225 31,569,152 RGD:11554173
G Col2a1 collagen type II alpha 1 chain JBrowse link 7 139,454,945 139,484,403 RGD:8657384
RGD:11554173
RGD:8661226
G Col6a2 collagen type VI alpha 2 chain JBrowse link 20 12,773,472 12,801,179 RGD:11554173
G Col9a1 collagen type IX alpha 1 chain JBrowse link 9 30,419,001 30,502,307 RGD:13592920
G Comp cartilage oligomeric matrix protein JBrowse link 16 20,798,437 20,807,070 RGD:11554173
G Ctsd cathepsin D JBrowse link 1 215,541,570 215,553,446 RGD:11554173
G Ctsk cathepsin K JBrowse link 2 196,655,469 196,666,447 RGD:11554173
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:11554173
G Cxcl6 C-X-C motif chemokine ligand 6 JBrowse link 14 18,860,201 18,920,839 RGD:11554173
G Dapp1 dual adaptor of phosphotyrosine and 3-phosphoinositides 1 JBrowse link 2 243,175,346 243,224,883 RGD:11554173
G Ddx3x DEAD-box helicase 3, X-linked JBrowse link X 10,400,363 10,414,010 RGD:11554173
G Dpep1 dipeptidase 1 JBrowse link 19 55,973,447 55,998,830 RGD:11554173
G Dpysl2 dihydropyrimidinase-like 2 JBrowse link 15 43,475,640 43,581,725 RGD:11554173
G Edil3 EGF like repeats and discoidin domains 3 JBrowse link 2 17,616,116 18,128,514 RGD:11554173
G Eef2 eukaryotic translation elongation factor 2 JBrowse link 7 11,401,501 11,406,771 RGD:11554173
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:1626498
G Eno1 enolase 1 JBrowse link 5 167,288,223 167,299,610 RGD:11554173
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 JBrowse link 1 21,748,201 21,813,205 RGD:13592920
G Epas1 endothelial PAS domain protein 1 JBrowse link 6 10,306,508 10,385,239 RGD:10395364
RGD:10395366
RGD:10395365
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:10045611
G Erg ETS transcription factor ERG JBrowse link 11 35,645,317 35,749,637 RGD:13592920
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:13592920
G Esd esterase D JBrowse link 15 56,756,848 56,776,348 RGD:11554173
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:10045662
RGD:10045830
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:10045830
G Etfa electron transfer flavoprotein subunit alpha JBrowse link 8 60,028,786 60,086,352 RGD:11554173
G Ezr ezrin JBrowse link 1 47,287,872 47,331,412 RGD:11554173
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:5147984
G Fgf18 fibroblast growth factor 18 JBrowse link 10 18,047,109 18,082,290 RGD:11554173
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:10402075
G Flt1 FMS-related tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:10402109
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:10402156
G Frzb frizzled-related protein JBrowse link 3 67,635,604 67,668,772 RGD:7240710
RGD:8554872
G Ftl1 ferritin light chain 1 JBrowse link 1 101,448,190 101,450,034 RGD:11554173
G Gapdh glyceraldehyde-3-phosphate dehydrogenase JBrowse link 4 157,676,336 157,680,322 RGD:11554173
G Gdf5 growth differentiation factor 5 JBrowse link 3 151,482,672 151,487,129 RGD:7240710
RGD:11554173
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:10003140
G Ghr growth hormone receptor JBrowse link 2 53,149,225 53,413,954 RGD:10003113
G Gls glutaminase JBrowse link 9 54,212,622 54,284,879 RGD:11554173
G Gstk1 glutathione S-transferase kappa 1 JBrowse link 4 71,621,777 71,626,096 RGD:11554173
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha JBrowse link 6 27,589,840 27,628,921 RGD:11554173
G Hbp1 HMG-box transcription factor 1 JBrowse link 6 51,231,479 51,257,699 RGD:10402054
G Hibch 3-hydroxyisobutyryl-CoA hydrolase JBrowse link 9 53,446,185 53,526,727 RGD:11554173
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:10395366
RGD:10402406
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:10401949
G Idh2 isocitrate dehydrogenase (NADP(+)) 2, mitochondrial JBrowse link 1 141,874,354 141,893,674 RGD:11554173
G Idh3a isocitrate dehydrogenase 3 (NAD+) alpha JBrowse link 8 59,164,601 59,183,899 RGD:11554173
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:10045857
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:10045889
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:10402552
G Igfbp3 insulin-like growth factor binding protein 3 JBrowse link 14 87,457,647 87,465,374 RGD:10402575
G Ihh Indian hedgehog signaling molecule JBrowse link 9 82,208,223 82,214,440 RGD:12910979
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:10047053
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:7207218
RGD:11554173
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:10402785
G Il5 interleukin 5 JBrowse link 10 39,066,716 39,069,587 RGD:5687147
G Immt inner membrane mitochondrial protein JBrowse link 4 99,753,446 99,789,921 RGD:11554173
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:10045857
G Isoc2b isochorismatase domain containing 2b JBrowse link 1 72,524,569 72,545,331 RGD:11554173
G Jag1 jagged canonical Notch ligand 1 JBrowse link 3 130,079,361 130,114,781 RGD:6482239
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:10053634
G Ltbp3 latent transforming growth factor beta binding protein 3 JBrowse link 1 221,099,155 221,116,096 RGD:11554173
G Matn3 matrilin 3 JBrowse link 6 34,071,428 34,091,048 RGD:7240710
RGD:8554872
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:7207129
G Mmp13 matrix metallopeptidase 13 JBrowse link 8 5,522,739 5,533,018 RGD:7207089
RGD:10043117
RGD:2300093
RGD:10043101
RGD:7207218
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:7207131
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:7207089
RGD:7207131
G Mmp8 matrix metallopeptidase 8 JBrowse link 8 5,768,808 5,777,741 RGD:7207131
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:7207131
G Msn moesin JBrowse link X 65,226,834 65,294,192 RGD:11554173
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:10003163
RGD:10003165
G Mvp major vault protein JBrowse link 1 198,420,813 198,448,612 RGD:11554173
G Myh13 myosin heavy chain 13 JBrowse link 10 53,921,077 53,927,553 RGD:11554173
G Napepld N-acyl phosphatidylethanolamine phospholipase D JBrowse link 4 9,965,323 10,004,650 RGD:10412653
G Ncor2 nuclear receptor co-repressor 2 JBrowse link 12 36,871,917 37,033,701 RGD:1625347
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 JBrowse link 1 219,141,289 219,144,610 RGD:11554173
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 JBrowse link 1 219,254,293 219,259,328 RGD:11554173
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 JBrowse link 10 81,648,216 81,653,717 RGD:11554173
G Opa1 OPA1, mitochondrial dynamin like GTPase JBrowse link 11 74,717,600 74,793,902 RGD:11554173
G P3h3 prolyl 3-hydroxylase 3 JBrowse link 4 157,359,331 157,375,186 RGD:11554173
G Pdcd6ip programmed cell death 6 interacting protein JBrowse link 8 121,916,233 121,973,145 RGD:11554173
G Pdha1 pyruvate dehydrogenase E1 alpha 1 subunit JBrowse link X 37,329,779 37,343,410 RGD:11554173
G Pecam1 platelet and endothelial cell adhesion molecule 1 JBrowse link 10 94,850,971 94,913,202 RGD:6771362
G Plcd1 phospholipase C, delta 1 JBrowse link 8 127,753,514 127,782,070 RGD:11554173
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 JBrowse link 8 99,977,334 100,059,736 RGD:11554173
G Pls3 plastin 3 JBrowse link X 119,030,311 119,124,268 RGD:11554173
G Pomc proopiomelanocortin JBrowse link 6 28,382,937 28,388,771 RGD:5508809
G Pou3f3 POU class 3 homeobox 3 JBrowse link 9 49,479,148 49,482,246 RGD:11554173
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:11554173
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha JBrowse link 1 60,717,386 60,736,629 RGD:11554173
G Psmb1 proteasome subunit beta 1 JBrowse link 1 57,470,878 57,491,359 RGD:11554173
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1625347
G Ran RAN, member RAS oncogene family JBrowse link 12 31,319,556 31,324,105 RGD:11554173
G Rcn3 reticulocalbin 3 JBrowse link 1 101,076,971 101,086,198 RGD:11554173
G Runx2 runt-related transcription factor 2 JBrowse link 9 18,564,743 18,773,092 RGD:11554173
G S100a4 S100 calcium-binding protein A4 JBrowse link 2 189,997,278 189,999,587 RGD:11554173
G Scrn1 secernin 1 JBrowse link 4 84,678,978 84,740,701 RGD:11554173
G Sdcbp syndecan binding protein JBrowse link 5 19,471,664 19,498,499 RGD:11554173
G Sdha succinate dehydrogenase complex flavoprotein subunit A JBrowse link 1 31,545,631 31,570,601 RGD:11554173
G Sec23a Sec23 homolog A, coat complex II component JBrowse link 6 80,059,742 80,107,340 RGD:11554173
G Serpina1 serpin family A member 1 JBrowse link 6 127,610,241 127,632,265 RGD:2324964
G Sgcg sarcoglycan, gamma JBrowse link 15 41,549,330 41,595,275 RGD:11554173
G Slc2a1 solute carrier family 2 member 1 JBrowse link 5 138,154,677 138,182,897 RGD:11554173
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:11554173
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:11554173
G Tent5a terminal nucleotidyltransferase 5A JBrowse link 8 92,935,474 92,942,267 RGD:14390133
G Tfpi2 tissue factor pathway inhibitor 2 JBrowse link 4 28,947,951 28,953,261 RGD:11554173
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:11554173
G Tgm2 transglutaminase 2 JBrowse link 3 154,597,165 154,627,257 RGD:11554173
G Tlr8 toll-like receptor 8 JBrowse link X 28,539,158 28,562,803 RGD:8554872
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b JBrowse link 15 51,433,853 51,464,215 RGD:2290500
G Tnfrsf11b TNF receptor superfamily member 11B JBrowse link 7 93,798,580 93,826,586 RGD:1625347
G Tnfsf10 TNF superfamily member 10 JBrowse link 2 113,008,008 113,026,899 RGD:2290500
G Tnfsf15 TNF superfamily member 15 JBrowse link 5 79,553,935 79,569,974 RGD:11554173
G Trap1 TNF receptor-associated protein 1 JBrowse link 10 11,724,032 11,757,682 RGD:11554173
G Trim2 tripartite motif-containing 2 JBrowse link 2 183,145,096 183,223,819 RGD:11554173
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:11554173
G Txnrd1 thioredoxin reductase 1 JBrowse link 7 26,946,124 26,984,400 RGD:11554173
G Vdac2 voltage-dependent anion channel 2 JBrowse link 15 2,634,622 2,648,548 RGD:11554173
G Vim vimentin JBrowse link 17 80,882,715 80,891,200 RGD:11554173
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta JBrowse link 6 43,463,294 43,493,816 RGD:11554173
Digital Arthropathy-Brachydactyly, Familial term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:7240710
RGD:8554872
Familial Osteochondritis Dissecans term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acan aggrecan JBrowse link 1 140,762,758 140,824,441 RGD:7240710
Knee Osteoarthritis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa2 annexin A2 JBrowse link 8 75,687,134 75,723,589 RGD:10053727
G Anxa5 annexin A5 JBrowse link 2 123,162,477 123,194,730 RGD:10053727
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:10043199
G Aspn asporin JBrowse link 17 14,655,958 14,681,355 RGD:9684965
G B2m beta-2 microglobulin JBrowse link 3 114,087,287 114,093,311 RGD:6482710
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6907382
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6907382
G Bglap bone gamma-carboxyglutamate protein JBrowse link 2 187,741,770 187,748,445 RGD:6483563
RGD:6483595
G Ccr2 C-C motif chemokine receptor 2 RGD:8661785
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6893494
RGD:6893565
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:10395278
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:10045662
G Dgat2 diacylglycerol O-acyltransferase 2 JBrowse link 1 164,113,459 164,143,818 RGD:6893494
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:6907382
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 JBrowse link 8 85,838,594 85,841,816 RGD:13506963
G Efemp1 EGF containing fibulin extracellular matrix protein 1 JBrowse link 14 113,202,382 113,294,993 RGD:10401792
G Epas1 endothelial PAS domain protein 1 JBrowse link 6 10,306,508 10,385,239 RGD:10395367
RGD:10395368
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:10400892
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:10043199
RGD:10045840
RGD:10045835
RGD:10045829
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:10043199
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:5147774
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:11568056
G Gdf5 growth differentiation factor 5 JBrowse link 3 151,482,672 151,487,129 RGD:11554173
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:10401830
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:10402061
RGD:10402184
G Hmgb2 high mobility group box 2 JBrowse link 16 36,077,615 36,080,191 RGD:10402184
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:10412655
RGD:10429075
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:10045862
RGD:10003130
RGD:10046057
RGD:10045868
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:10045874
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:10045944
RGD:10046057
RGD:10045946
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:5687147
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:2317291
RGD:10402787
G Kl Klotho JBrowse link 12 942,974 987,206 RGD:10403041
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:10411887
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:10411887
G Lpar1 lysophosphatidic acid receptor 1 JBrowse link 5 75,557,038 75,678,067 RGD:10054291
G Ltbp1 latent transforming growth factor beta binding protein 1 JBrowse link 6 21,203,502 21,600,441 RGD:11554173
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:8549737
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:8694098
G Penk proenkephalin JBrowse link 5 17,056,412 17,061,762 RGD:10003115
G Ptges prostaglandin E synthase JBrowse link 3 9,727,408 9,738,752 RGD:2300093
G Sbno1 strawberry notch homolog 1 JBrowse link 12 37,593,692 37,650,761 RGD:11554173
G Slc26a2 solute carrier family 26 member 2 JBrowse link 18 56,518,999 56,534,539 RGD:13208866
G Tgfa transforming growth factor alpha JBrowse link 4 117,961,877 118,045,923 RGD:2317486
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:1331525
G Wwp2 WW domain containing E3 ubiquitin protein ligase 2 JBrowse link 19 39,543,246 39,614,624 RGD:11554173
Osteoarthritis with Mild Chondrodysplasia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col2a1 collagen type II alpha 1 chain JBrowse link 7 139,454,945 139,484,403 RGD:7240710
RGD:8554872
Osteoarthritis, Experimental term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:11561955
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:9068434
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:13782275
G Casp6 caspase 6 JBrowse link 2 235,341,326 235,353,715 RGD:13782275
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:13782275
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:13782275
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:11041187
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:10402072
G Flt1 FMS-related tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:10402106
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:10402538
G Lrpap1 LDL receptor related protein associated protein 1 JBrowse link 14 80,911,281 80,923,290 RGD:10412054
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha JBrowse link 3 150,801,289 150,802,935 RGD:11561955
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:13800565
G Ulk1 unc-51 like autophagy activating kinase 1 JBrowse link 12 51,908,105 51,934,704 RGD:11561955
Osteoarthritis, Hand term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:10045830
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:10045830
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:10402786
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:10402786
G Matn3 matrilin 3 JBrowse link 6 34,071,428 34,091,048 RGD:8554872
Osteoarthritis, Hip term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 JBrowse link 11 25,411,174 25,456,639 RGD:10043109
G Aspn asporin JBrowse link 17 14,655,958 14,681,355 RGD:9684965
G Astn2 astrotactin 2 JBrowse link 5 81,179,614 82,168,528 RGD:11554173
G Chadl chondroadherin-like JBrowse link 7 122,915,847 122,929,127 RGD:11554173
G Col10a1 collagen type X alpha 1 chain JBrowse link 20 41,180,295 41,190,664 RGD:10043109
G Col11a1 collagen type XI alpha 1 chain JBrowse link 2 216,863,423 217,056,523 RGD:11554173
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:5688305
RGD:5688306
RGD:5688330
G Comp cartilage oligomeric matrix protein JBrowse link 16 20,798,437 20,807,070 RGD:11554173
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link 10 92,191,473 92,233,662 RGD:11554173
G Diablo diablo, IAP-binding mitochondrial protein JBrowse link 12 38,490,230 38,503,344 RGD:11554173
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:10045661
G Filip1 filamin A interacting protein 1 JBrowse link 8 87,257,312 87,453,432 RGD:11554173
G Gdf5 growth differentiation factor 5 JBrowse link 3 151,482,672 151,487,129 RGD:8554872
G Ghr growth hormone receptor JBrowse link 2 53,149,225 53,413,954 RGD:10003142
G Hdac9 histone deacetylase 9 JBrowse link 6 53,487,367 54,358,694 RGD:11554173
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:11554173
G Il11 interleukin 11 JBrowse link 1 72,636,959 72,643,255 RGD:11554173
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:10402782
RGD:10402784
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 JBrowse link 16 7,012,376 7,026,542 RGD:11554173
G Lmx1b LIM homeobox transcription factor 1 beta JBrowse link 3 12,608,748 12,686,937 RGD:11554173
G Ltbp3 latent transforming growth factor beta binding protein 3 JBrowse link 1 221,099,155 221,116,096 RGD:11554173
G Mapt microtubule-associated protein tau JBrowse link 10 92,289,002 92,386,517 RGD:11554173
G Mmp13 matrix metallopeptidase 13 JBrowse link 8 5,522,739 5,533,018 RGD:10043109
G Runx2 runt-related transcription factor 2 JBrowse link 9 18,564,743 18,773,092 RGD:11554173
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:11554173
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:11554173
G Tnc tenascin C JBrowse link 5 79,789,686 79,874,555 RGD:11554173
Osteoarthritis, Temporomandibular Joint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:8663479
Spine Osteoarthritis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp5 LDL receptor related protein 5 JBrowse link 1 218,816,833 218,920,147 RGD:12792278

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14823
    Diseases of the Aged 1152
      osteoarthritis 220
        Brachydactylous Dwarfism Mseleni Type 0
        Chondrocalcinosis 1 0
        Digital Arthropathy-Brachydactyly, Familial 1
        Familial Osteochondritis Dissecans 1
        Knee Osteoarthritis 46
        Osteoarthritis with Mild Chondrodysplasia 1
        Osteoarthritis, Experimental 14
        Osteoarthritis, Hand 5
        Osteoarthritis, Hip 27
        Osteoarthritis, Temporomandibular Joint 1
        Spine Osteoarthritis 1
Path 2
Term Annotations click to browse term
  disease 14823
    disease of anatomical entity 13997
      Immune & Inflammatory Diseases 3007
        immune system disease 2440
          hypersensitivity reaction disease 1488
            autoimmune hypersensitivity disease 1197
              autoimmune disease of musculoskeletal system 814
                rheumatic disease 801
                  osteoarthritis 220
                    Brachydactylous Dwarfism Mseleni Type 0
                    Chondrocalcinosis 1 0
                    Digital Arthropathy-Brachydactyly, Familial 1
                    Familial Osteochondritis Dissecans 1
                    Knee Osteoarthritis 46
                    Osteoarthritis with Mild Chondrodysplasia 1
                    Osteoarthritis, Experimental 14
                    Osteoarthritis, Hand 5
                    Osteoarthritis, Hip 27
                    Osteoarthritis, Temporomandibular Joint 1
                    Spine Osteoarthritis 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.