ONTOLOGY REPORT - ANNOTATIONS


Term:Sezary's disease
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Accession:DOID:8541 term browser browse the term
Definition:A form of cutaneous T-cell lymphoma manifested by generalized exfoliative ERYTHRODERMA; PRURITUS; peripheral lymphadenopathy, and abnormal hyperchromatic mononuclear (cerebriform) cells in the skin, LYMPH NODES, and peripheral blood (Sezary cells).
Synonyms:exact_synonym: Sezary Erythroderma;   Sezary Lymphoma;   Sezary disease;   Sezary syndrome;   Sezary's Lymphoma;   Sezarys Lymphoma
 narrow_synonym: SEZARY SYNDROME, SOMATIC
 primary_id: MESH:D012751;   RDO:0006557
 xref: GARD:7629
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Sezary's disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arid1a AT-rich interaction domain 1A JBrowse link 5 151,904,687 151,977,973 RGD:11554173
G Bcl10 BCL10, immune signaling adaptor JBrowse link 2 251,805,392 251,814,957 RGD:8554872
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:11554173
G Brd9 bromodomain containing 9 JBrowse link 1 31,939,612 31,968,120 RGD:11554173
G Card11 caspase recruitment domain family, member 11 JBrowse link 12 15,700,600 15,844,512 RGD:11554173
G Ccr4 C-C motif chemokine receptor 4 JBrowse link 8 122,530,152 122,535,959 RGD:11554173
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:11554173
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:11554173
G Chd3 chromodomain helicase DNA binding protein 3 JBrowse link 10 55,943,467 55,970,417 RGD:11554173
G Crebbp CREB binding protein JBrowse link 10 11,590,994 11,721,039 RGD:11554173
G Dnmt3a DNA methyltransferase 3 alpha JBrowse link 6 28,205,375 28,346,052 RGD:11554173
G Il2rg interleukin 2 receptor subunit gamma JBrowse link X 71,165,378 71,169,078 RGD:11554173
G Kmt2c lysine methyltransferase 2C JBrowse link 4
4
82,506
6,083,650
109,986
6,294,413
RGD:11554173
G Kmt2d lysine methyltransferase 2D JBrowse link 7 140,507,137 140,542,479 RGD:11554173
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:11554173
G Plcg1 phospholipase C, gamma 1 JBrowse link 3 156,727,642 156,758,307 RGD:11554173
G Prkg1 protein kinase cGMP-dependent 1 JBrowse link 1 248,982,039 250,300,952 RGD:11554173
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:11554173
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:11554173
G Rps6ka1 ribosomal protein S6 kinase A1 JBrowse link 5 152,078,217 152,122,684 RGD:11554173
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 JBrowse link 8 22,648,323 22,739,468 RGD:11554173
G Stat4 signal transducer and activator of transcription 4 JBrowse link 9 54,340,649 54,457,753 RGD:8661723
G Tet2 tet methylcytosine dioxygenase 2 JBrowse link 2 238,719,389 238,802,975 RGD:11554173
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link 5 163,136,390 163,167,299 RGD:11554173
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:11554173
G Zeb1 zinc finger E-box binding homeobox 1 JBrowse link 17 54,656,627 54,714,920 RGD:11554173

Term paths to the root
Path 1
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  disease 14875
    syndrome 4220
      Sezary's disease 26
Path 2
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  disease 14875
    disease of anatomical entity 14051
      Immune & Inflammatory Diseases 2988
        immune system disease 2414
          Immunoproliferative Disorders 595
            lymphoproliferative syndrome 590
              lymphoma 334
                non-Hodgkin lymphoma 286
                  mature T-cell and NK-cell lymphoma 54
                    peripheral T-cell lymphoma 54
                      cutaneous T cell lymphoma 50
                        Sezary's disease 26
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.