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ONTOLOGY REPORT - ANNOTATIONS


Term:in situ carcinoma
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Accession:DOID:8719 term browser browse the term
Definition:A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane.
Synonyms:exact_synonym: Intraepithelial Carcinoma;   Intraepithelial Neoplasm;   Intraepithelial Neoplasms;   Preinvasive Carcinoma
 primary_id: MESH:D002278;   RDO:0001215
 xref: ICD10CM:D09.9;   ICD9CM:230-234.99;   ICD9CM:234.9;   NCI:C2917
For additional species annotation, visit the Alliance of Genome Resources.


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in situ carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:2325208
G Agr2 anterior gradient 2, protein disulphide isomerase family member JBrowse link 6 55,465,782 55,487,087 RGD:2325658
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1643333
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:2317522
G Alpl alkaline phosphatase, biomineralization associated JBrowse link 5 156,086,496 156,141,513 RGD:2315616
G Angpt1 angiopoietin 1 JBrowse link 7 81,338,327 81,592,459 RGD:1626167
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:2298754
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:2296040
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:2296048
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:2289836
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:2290024
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:2290024
G Igf2r insulin-like growth factor 2 receptor JBrowse link 1 48,176,095 48,264,482 RGD:2311631
G Igfbp6 insulin-like growth factor binding protein 6 JBrowse link 7 143,749,385 143,754,018 RGD:2301712
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:2317703
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:2292154
G Pdpn podoplanin JBrowse link 5 161,947,137 161,981,441 RGD:2292235
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:2292428
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:2289828
G Ptges prostaglandin E synthase JBrowse link 3 9,727,408 9,738,752 RGD:2300088
RGD:2300087
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:2317187
RGD:11554173
RGD:2317186
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:2299891
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:2314696
G Runx3 RUNX family transcription factor 3 JBrowse link 5 153,507,093 153,531,137 RGD:2324958
G Sfn stratifin JBrowse link 5 151,823,422 151,824,937 RGD:2299936
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:2301712
G Xrcc1 X-ray repair cross complementing 1 JBrowse link 1 81,412,635 81,441,680 RGD:10045659
G Zfp354a zinc finger protein 354A JBrowse link 10 36,586,495 36,600,172 RGD:2291889
adenocarcinoma in situ term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fancf FA complementation group F JBrowse link 1 107,229,516 107,232,321 RGD:11049137
breast carcinoma in situ term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Igf2r insulin-like growth factor 2 receptor JBrowse link 1 48,176,095 48,264,482 RGD:2311631
cervix uteri carcinoma in situ term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam9 ADAM metallopeptidase domain 9 JBrowse link 16 71,810,377 71,887,926 RGD:2325246
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:2298889
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:2298942
G Cadm1 cell adhesion molecule 1 JBrowse link 8 51,858,906 52,200,591 RGD:2289089
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:2293574
G Ccne1 cyclin E1 JBrowse link 1 94,485,830 94,495,112 RGD:2293574
G Ccng1 cyclin G1 JBrowse link 10 25,903,925 25,910,298 RGD:2316022
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:2293549
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:2289490
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:2293574
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:8662446
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:2293574
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:2296058
RGD:2289676
RGD:2289675
RGD:2296054
G Cdkn2a_v1 cyclin-dependent kinase inhibitor 2A, variant 1 RGD:2289675
RGD:2289676
G Cdkn2b cyclin-dependent kinase inhibitor 2B JBrowse link 5 107,834,353 107,857,428 RGD:2289695
G Csf1r colony stimulating factor 1 receptor JBrowse link 18 56,414,493 56,458,300 RGD:2299119
G Ctnna1 catenin alpha 1 JBrowse link 18 27,923,229 28,055,972 RGD:2289797
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:2290052
G Hdac1 histone deacetylase 1 JBrowse link 5 147,716,664 147,743,723 RGD:2306200
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:2306200
G Hdac6 histone deacetylase 6 JBrowse link X 15,295,372 15,316,673 RGD:2306200
G Igfbp3 insulin-like growth factor binding protein 3 JBrowse link 14 87,457,647 87,465,374 RGD:2290021
RGD:2290004
G Mgp matrix Gla protein JBrowse link 4 170,856,783 170,860,105 RGD:2293584
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:2293515
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:2290402
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:2293515
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:11554173
G Phb prohibitin JBrowse link 10 83,476,107 83,488,878 RGD:2292398
G Pou4f1 POU class 4 homeobox 1 JBrowse link 15 88,618,255 88,622,712 RGD:11554173
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:2298701
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:2299119
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:2299896
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:2298759
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:2306230
RGD:2306232
RGD:2314703
G Skp2 S-phase kinase associated protein 2 JBrowse link 2 58,506,146 58,534,211 RGD:2315036
G Srsf1 serine and arginine rich splicing factor 1 JBrowse link 10 75,334,200 75,341,197 RGD:11039410
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:2298536
RGD:2291916
G Terc telomerase RNA component JBrowse link 2 116,432,723 116,433,110 RGD:2291968
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:2291985
G Thrb thyroid hormone receptor beta JBrowse link 15 8,890,578 9,239,815 RGD:2315099
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:2301099
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:2315126
G Tp63 tumor protein p63 JBrowse link 11 78,234,853 78,456,559 RGD:2315435
G Tp73 tumor protein p73 JBrowse link 5 171,355,876 171,415,354 RGD:2290589
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:2315456
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:2315850
ductal carcinoma in situ term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:10053629
G Ang angiogenin JBrowse link 15 28,022,926 28,028,636 RGD:2325702
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:7421537
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1643341
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:2292664
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:2289659
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:2293106
G Bnip3 BCL2 interacting protein 3 JBrowse link 1 211,248,098 211,265,282 RGD:7483575
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:2289048
G Ca9 carbonic anhydrase 9 JBrowse link 5 59,008,277 59,015,535 RGD:11554173
G Casp6 caspase 6 JBrowse link 2 235,341,326 235,353,715 RGD:2301339
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:2289132
G Ccnd2 cyclin D2 JBrowse link 4 159,674,885 159,697,207 RGD:2289156
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:2289659
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:2289981
RGD:2289931
G Erbb3 erb-b2 receptor tyrosine kinase 3 JBrowse link 7 2,989,202 3,010,610 RGD:2289952
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:2289981
G Flt1 Fms related receptor tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:2289965
G Fosl1 FOS like 1, AP-1 transcription factor subunit JBrowse link 1 220,826,560 220,835,066 RGD:2293756
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:2306227
RGD:11554173
G Hoxb13 homeo box B13 JBrowse link 10 84,031,955 84,034,228 RGD:2314726
G Klk10 kallikrein related-peptidase 10 JBrowse link 1 99,718,275 99,722,743 RGD:2314849
G Ldhb lactate dehydrogenase B JBrowse link 4 176,701,980 176,719,999 RGD:11554173
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:2290392
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:2290436
G Notch4 notch receptor 4 JBrowse link 20 4,329,794 4,353,868 RGD:2299156
G Pak2 p21 (RAC1) activated kinase 2 JBrowse link 11 72,829,407 72,865,815 RGD:7775026
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:2289659
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:2292458
G Ptges prostaglandin E synthase JBrowse link 3 9,727,408 9,738,752 RGD:2300083
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:2300203
RGD:2300199
G Ptk2 protein tyrosine kinase 2 JBrowse link 7 114,436,419 114,611,317 RGD:2292561
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:2299890
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:2298754
G Slc2a1 solute carrier family 2 member 1 JBrowse link 5 138,154,677 138,182,897 RGD:11554173
G Socs1 suppressor of cytokine signaling 1 JBrowse link 10 4,956,795 4,958,472 RGD:2298909
G Socs2 suppressor of cytokine signaling 2 JBrowse link 7 36,495,496 36,500,878 RGD:2298909
G Socs3 suppressor of cytokine signaling 3 JBrowse link 10 106,973,863 106,976,969 RGD:2298909
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:2315078
G St14 suppression of tumorigenicity 14 JBrowse link 8 32,240,113 32,280,813 RGD:2315089
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:2291932
RGD:11554173
RGD:2291930
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:2291992
G Tff1 trefoil factor 1 JBrowse link 20 9,892,124 9,895,984 RGD:2292005
G Timp2 TIMP metallopeptidase inhibitor 2 JBrowse link 10 107,338,465 107,386,072 RGD:2290436
G Timp4 TIMP metallopeptidase inhibitor 4 JBrowse link 4 147,156,948 147,163,467 RGD:2290436
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:2315133
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:2289931
G Tymp thymidine phosphorylase JBrowse link 7 130,342,481 130,347,845 RGD:2293726
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:2315458
mammary Paget's disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:2289933
prostate carcinoma in situ term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amacr alpha-methylacyl-CoA racemase JBrowse link 2 60,949,276 60,961,342 RGD:2315630
G Ang angiogenin JBrowse link 15 28,022,926 28,028,636 RGD:2325697
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 JBrowse link 15 27,849,943 27,852,083 RGD:2315666
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:11554173
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:2292659
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:2293869
G Aurka aurora kinase A JBrowse link 3 170,364,177 170,380,278 RGD:2293883
RGD:2293877
G Aurkb aurora kinase B JBrowse link 10 55,625,860 55,632,399 RGD:2293877
G Btg2 BTG anti-proliferation factor 2 JBrowse link 13 50,913,185 50,916,944 RGD:2289070
G Carm1 coactivator-associated arginine methyltransferase 1 JBrowse link 8 22,577,723 22,622,555 RGD:2293206
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:2289283
G Ccne1 cyclin E1 JBrowse link 1 94,485,830 94,495,112 RGD:2289283
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:11554173
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:2299085
RGD:11554173
G Creb3l4 cAMP responsive element binding protein 3-like 4 JBrowse link 2 189,596,657 189,602,243 RGD:13504714
G Csf1r colony stimulating factor 1 receptor JBrowse link 18 56,414,493 56,458,300 RGD:2293712
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:7257711
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:11554173
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:8553211
RGD:11554173
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:8553211
RGD:11554173
G Fgf6 fibroblast growth factor 6 JBrowse link 4 159,563,798 159,572,333 RGD:2301089
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:2301097
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:2298702
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:2301192
G Flt1 Fms related receptor tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:2301255
G Fzd4 frizzled class receptor 4 JBrowse link 1 153,589,471 153,598,376 RGD:2298702
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:10401940
RGD:11554173
G Hdac1 histone deacetylase 1 JBrowse link 5 147,716,664 147,743,723 RGD:2306219
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:2306713
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:2314913
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:11531513
G Lrp1 LDL receptor related protein 1 JBrowse link 7 70,846,313 70,927,028 RGD:1625030
G Map2k4 mitogen activated protein kinase kinase 4 JBrowse link 10 52,196,121 52,301,887 RGD:2293334
G Map2k6 mitogen-activated protein kinase kinase 6 JBrowse link 10 98,707,160 98,823,054 RGD:2293334
G Map2k7 mitogen activated protein kinase kinase 7 JBrowse link 12 2,546,278 2,555,310 RGD:2293334
G Mt2A metallothionein 2A JBrowse link 19 11,307,966 11,308,740 RGD:11554173
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:10059615
G Phb prohibitin JBrowse link 10 83,476,107 83,488,878 RGD:2292382
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase JBrowse link 20 8,165,423 8,169,557 RGD:11554173
G Prss8 serine protease 8 JBrowse link 1 199,372,519 199,377,035 RGD:2292484
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:2292497
RGD:11554173
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:2300123
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:2298767
RGD:2298769
G Rxra retinoid X receptor alpha JBrowse link 3 6,272,560 6,295,354 RGD:1643115
G Slc30a4 solute carrier family 30 member 4 JBrowse link 3 114,805,919 114,828,154 RGD:2299948
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:2300005
G St14 suppression of tumorigenicity 14 JBrowse link 8 32,240,113 32,280,813 RGD:2315088
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:2291943
G Timp4 TIMP metallopeptidase inhibitor 4 JBrowse link 4 147,156,948 147,163,467 RGD:2290433
G Top2b DNA topoisomerase II beta JBrowse link 15 10,262,972 10,319,741 RGD:11554173
G Tp63 tumor protein p63 JBrowse link 11 78,234,853 78,456,559 RGD:2315434
RGD:11554173
RGD:2315433

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15609
    disease of cellular proliferation 5822
      pre-malignant neoplasm 284
        in situ carcinoma 140
          Rokitansky-Aschoff Sinuses of the Gallbladder 0
          adenocarcinoma in situ 1
          anal carcinoma in situ 0
          bile duct carcinoma in situ 0
          bladder carcinoma in situ 0
          breast carcinoma in situ + 50
          bronchus carcinoma in situ 0
          endometrium carcinoma in situ 0
          esophagus carcinoma in situ 0
          eye carcinoma in situ 0
          gallbladder carcinoma in situ 0
          intestine carcinoma in situ + 0
          kidney carcinoma in situ 0
          larynx carcinoma in situ 0
          liver carcinoma in situ 0
          lung carcinoma in situ + 0
          nasal cavity carcinoma in situ 0
          oral cavity carcinoma in situ + 0
          penis carcinoma in situ 0
          pharynx carcinoma in situ 0
          prostate carcinoma in situ 51
          rectum carcinoma in situ 0
          skin carcinoma in situ 0
          stomach carcinoma in situ 0
          trachea carcinoma in situ 0
          uterus carcinoma in situ + 46
Path 2
Term Annotations click to browse term
  disease 15609
    disease of cellular proliferation 5822
      cancer 4157
        cell type cancer 3054
          carcinoma 1913
            in situ carcinoma 140
              Rokitansky-Aschoff Sinuses of the Gallbladder 0
              adenocarcinoma in situ 1
              anal carcinoma in situ 0
              bile duct carcinoma in situ 0
              bladder carcinoma in situ 0
              breast carcinoma in situ + 50
              bronchus carcinoma in situ 0
              endometrium carcinoma in situ 0
              esophagus carcinoma in situ 0
              eye carcinoma in situ 0
              gallbladder carcinoma in situ 0
              intestine carcinoma in situ + 0
              kidney carcinoma in situ 0
              larynx carcinoma in situ 0
              liver carcinoma in situ 0
              lung carcinoma in situ + 0
              nasal cavity carcinoma in situ 0
              oral cavity carcinoma in situ + 0
              penis carcinoma in situ 0
              pharynx carcinoma in situ 0
              prostate carcinoma in situ 51
              rectum carcinoma in situ 0
              skin carcinoma in situ 0
              stomach carcinoma in situ 0
              trachea carcinoma in situ 0
              uterus carcinoma in situ + 46
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.