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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular dementia
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Accession:DOID:8725 term browser browse the term
Definition:An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)
Synonyms:exact_synonym: Arteriosclerotic Dementia;   Arteriosclerotic Dementias;   Binswanger Disease;   Binswanger Encephalopathy;   Binswanger's Disease;   Binswanger's Encephalopathy;   Binswangers Disease;   Chronic Progressive Subcortical Encephalopathy;   Encephalopathy, Binswangers;   Multi Infarct Dementia;   Subcortical Arteriosclerotic Encephalopathies;   Subcortical Arteriosclerotic Encephalopathy;   Subcortical Leukoencephalopathies;   Subcortical Leukoencephalopathy;   Subcortical Vascular Dementia;   Subcortical Vascular Dementias;   acute onset vascular dementia;   multifocal dementia;   vascular dementias
 primary_id: MESH:D015140
 alt_id: RDO:0006843
 xref: ICD10CM:F01;   ICD10CM:F01.5;   ICD9CM:290.4;   NCI:C34522;   NCI:C34525
For additional species annotation, visit the Alliance of Genome Resources.


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vascular dementia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp5f1a ATP synthase F1 subunit alpha JBrowse link NW_004955402 31,652,226 31,662,114 RGD:9068941
G Bdnf brain derived neurotrophic factor JBrowse link NW_004955476 6,773,244 6,822,201 RGD:9068941
G Cdk5 cyclin dependent kinase 5 JBrowse link NW_004955491 5,491,744 5,497,280 RGD:9068941
G Eif4e eukaryotic translation initiation factor 4E JBrowse link NW_004955405 9,122,960 9,159,095 RGD:9068941
G Epo erythropoietin JBrowse link NW_004955573 203,875 206,078 RGD:9068941
G Fgfr1 fibroblast growth factor receptor 1 JBrowse link NW_004955463 14,013,247 14,064,354 RGD:9068941
G Flt1 fms related receptor tyrosine kinase 1 JBrowse link NW_004955497 7,653,309 7,831,737 RGD:9068941
G Gclm glutamate-cysteine ligase modifier subunit JBrowse link NW_004955423 782,468 805,384 RGD:9068941
G Gpx1 glutathione peroxidase 1 JBrowse link NW_004955532 1,298,336 1,298,830 RGD:9068941
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link NW_004955513 5,154,864 5,178,636 RGD:9068941
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link NW_004955442 8,171,114 8,565,187 RGD:9068941
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B JBrowse link NW_004955413 10,358,931 10,780,004 RGD:9068941
G Gsk3b glycogen synthase kinase 3 beta JBrowse link NW_004955427 19,489,972 19,671,137 RGD:9068941
G Igf1 insulin like growth factor 1 JBrowse link NW_004955405 37,505,830 37,582,152 RGD:9068941
G Igf1r insulin like growth factor 1 receptor JBrowse link NW_004955416 26,101,090 26,382,660 RGD:9068941
G Il1b interleukin 1 beta JBrowse link NW_004955470 1,486,936 1,491,888 RGD:9068941
G Mapt microtubule associated protein tau JBrowse link NW_004955478 10,222,439 10,271,439 RGD:9068941
G Mmp2 matrix metallopeptidase 2 JBrowse link NW_004955433 13,024,844 13,050,041 RGD:9068941
G Mtor mechanistic target of rapamycin kinase JBrowse link NW_004955486 2,487,642 2,599,694 RGD:9068941
G Pon2 paraoxonase 2 JBrowse link NW_004955432 11,988,009 12,020,702 RGD:9068941
G Rpgrip1l RPGRIP1 like JBrowse link NW_004955433 11,321,504 11,423,981 RGD:9068941
G Rps6 ribosomal protein S6 JBrowse link NW_004955434 21,744,045 21,745,646 RGD:9068941
G Sdhaf1 succinate dehydrogenase complex assembly factor 1 JBrowse link NW_004955468 2,590,592 2,591,669 RGD:9068941
G Snca synuclein alpha JBrowse link NW_004955405 854,011 962,741 RGD:9068941
G Sncg synuclein gamma JBrowse link NW_004955510 5,958,276 5,961,719 RGD:9068941
G Srebf2 sterol regulatory element binding transcription factor 2 JBrowse link NW_004955413 27,271,717 27,326,655 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004955437 117,267 119,899 RGD:9068941
G Tp53 tumor protein p53 JBrowse link NW_004955467 9,241,391 9,256,716 RGD:9068941
CADASIL term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Htra1 HtrA serine peptidase 1 JBrowse link NW_004955477 761,127 808,396 RGD:9068941
G Notch3 notch receptor 3 JBrowse link NW_004955495 8,012,370 8,048,616 RGD:9068941
CADASIL 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Notch3 notch receptor 3 JBrowse link NW_004955495 8,012,370 8,048,616 RGD:7240710
CADASIL 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Htra1 HtrA serine peptidase 1 JBrowse link NW_004955477 761,127 808,396 RGD:7240710
Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Htra1 HtrA serine peptidase 1 JBrowse link NW_004955477 761,127 808,396 RGD:7240710
Multi-Infarct Dementia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G App amyloid beta precursor protein JBrowse link NW_004955407 25,725,259 25,973,582 RGD:9068941
G Bax BCL2 associated X, apoptosis regulator JBrowse link NW_004955559 1,695,960 1,700,246 RGD:9068941
G Bcl2 BCL2 apoptosis regulator JBrowse link NW_004955402 46,911,125 47,084,214 RGD:9068941
G G6pd glucose-6-phosphate dehydrogenase JBrowse link NW_004955580 1,045,294 1,058,129 RGD:9068941
G Il2 interleukin 2 JBrowse link NW_004955428 18,163,010 18,168,157 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11706
    Diseases of the Aged 908
      dementia 579
        vascular dementia 35
          CADASIL + 2
          Multi-Infarct Dementia 5
Path 2
Term Annotations click to browse term
  disease 11706
    disease of anatomical entity 11291
      nervous system disease 9190
        central nervous system disease 7711
          brain disease 7080
            disease of mental health 5055
              cognitive disorder 1573
                dementia 579
                  vascular dementia 35
                    CADASIL + 2
                    Multi-Infarct Dementia 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.