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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular dementia
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Accession:DOID:8725 term browser browse the term
Definition:An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)
Synonyms:exact_synonym: Arteriosclerotic Dementia;   Arteriosclerotic Dementias;   Binswanger Disease;   Binswanger Encephalopathy;   Binswanger's Disease;   Binswanger's Encephalopathy;   Binswangers Disease;   Chronic Progressive Subcortical Encephalopathy;   Encephalopathy, Binswangers;   Multi Infarct Dementia;   Subcortical Arteriosclerotic Encephalopathies;   Subcortical Arteriosclerotic Encephalopathy;   Subcortical Leukoencephalopathies;   Subcortical Leukoencephalopathy;   Subcortical Vascular Dementia;   Subcortical Vascular Dementias;   acute onset vascular dementia;   multifocal dementia;   vascular dementias
 primary_id: MESH:D015140
 alt_id: RDO:0006843
 xref: ICD10CM:F01;   ICD10CM:F01.5;   ICD9CM:290.4;   NCI:C34522;   NCI:C34525
For additional species annotation, visit the Alliance of Genome Resources.


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vascular dementia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP5F1A ATP synthase F1 subunit alpha JBrowse link 7 45,118,188 45,127,048 RGD:9068941
G AVP arginine vasopressin JBrowse link 24 18,183,057 18,184,827 RGD:9068941
G BDNF brain derived neurotrophic factor JBrowse link 21 48,191,580 48,243,699 RGD:9068941
G CDK5 cyclin dependent kinase 5 JBrowse link 16 15,105,177 15,113,085 RGD:9068941
G EIF4E eukaryotic translation initiation factor 4E JBrowse link 32 21,064,202 21,108,998 RGD:9068941
G EPO erythropoietin JBrowse link 6 8,994,211 8,995,954 RGD:9068941
G FGFR1 fibroblast growth factor receptor 1 JBrowse link 16 27,029,902 27,080,514 RGD:9068941
G FLT1 fms related receptor tyrosine kinase 1 JBrowse link 25 11,231,958 11,410,379 RGD:9068941
G GCLM glutamate-cysteine ligase modifier subunit JBrowse link 6 55,204,602 55,244,217 RGD:9068941
G GPX1 glutathione peroxidase 1 JBrowse link 20 39,889,165 39,890,253 RGD:9068941
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 9 48,492,967 48,513,981 RGD:9068941
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 6 32,132,070 32,678,319 RGD:9068941
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 27 32,470,889 32,883,606 RGD:9068941
G GSK3B glycogen synthase kinase 3 beta JBrowse link 33 23,458,369 23,659,878 RGD:9068941
G IGF1 insulin like growth factor 1 JBrowse link 15 41,203,320 41,275,964 RGD:9068941
G IGF1R insulin like growth factor 1 receptor JBrowse link 3 41,795,337 42,096,255 RGD:9068941
G IL1B interleukin 1 beta JBrowse link 17 37,019,329 37,033,388 RGD:9068941
G MAPT microtubule associated protein tau JBrowse link 9 9,572,174 9,674,082 RGD:9068941
G MMP2 matrix metallopeptidase 2 JBrowse link 2 60,471,092 60,492,991 RGD:9068941
G MTOR mechanistic target of rapamycin kinase JBrowse link 2 84,818,893 84,939,283 RGD:9068941
G PON2 paraoxonase 2 JBrowse link 14 20,652,905 20,680,945 RGD:9068941
G RPGRIP1L RPGRIP1 like JBrowse link 2 62,080,159 62,179,694 RGD:9068941
G RPS6 ribosomal protein S6 JBrowse link 11 39,161,422 39,165,148 RGD:9068941
G SDHAF1 succinate dehydrogenase complex assembly factor 1 JBrowse link 1 116,688,153 116,689,278 RGD:9068941
G SNCA synuclein alpha JBrowse link 32 12,915,871 13,079,338 RGD:9068941
G SNCG synuclein gamma JBrowse link 4 34,604,867 34,608,851 RGD:9068941
G SREBF2 sterol regulatory element binding transcription factor 2 JBrowse link 10 23,451,923 23,532,765 RGD:9068941
G SST somatostatin JBrowse link 34 20,063,091 20,064,520 RGD:9068941
G TNF tumor necrosis factor JBrowse link 12 1,074,561 1,076,425 RGD:9068941
G TP53 tumor protein p53 JBrowse link 5 32,561,406 32,565,149 RGD:9068941
CADASIL term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HTRA1 HtrA serine peptidase 1 JBrowse link 28 32,133,779 32,157,835 RGD:9068941
G NOTCH3 notch receptor 3 JBrowse link 20 46,946,654 46,978,821 RGD:9068941
CADASIL 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NOTCH3 notch receptor 3 JBrowse link 20 46,946,654 46,978,821 RGD:7240710
CADASIL 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HTRA1 HtrA serine peptidase 1 JBrowse link 28 32,133,779 32,157,835 RGD:7240710
Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HTRA1 HtrA serine peptidase 1 JBrowse link 28 32,133,779 32,157,835 RGD:7240710
Multi-Infarct Dementia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APP amyloid beta precursor protein JBrowse link 31 21,351,207 21,614,466 RGD:9068941
G BAX BCL2 associated X, apoptosis regulator JBrowse link 1 107,423,388 107,426,464 RGD:9068941
G BCL2 BCL2 apoptosis regulator JBrowse link 1 13,733,849 13,900,653 RGD:9068941
G G6PD glucose-6-phosphate dehydrogenase JBrowse link X 122,217,317 122,231,862 RGD:9068941
G IL2 interleukin 2 JBrowse link 19 17,750,780 17,756,394 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12601
    Diseases of the Aged 980
      dementia 630
        vascular dementia 37
          CADASIL + 2
          Multi-Infarct Dementia 5
Path 2
Term Annotations click to browse term
  disease 12601
    disease of anatomical entity 12145
      nervous system disease 9867
        central nervous system disease 8264
          brain disease 7602
            disease of mental health 5472
              cognitive disorder 1695
                dementia 630
                  vascular dementia 37
                    CADASIL + 2
                    Multi-Infarct Dementia 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.