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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular dementia
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Accession:DOID:8725 term browser browse the term
Definition:An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)
Synonyms:exact_synonym: Arteriosclerotic Dementia;   Arteriosclerotic Dementias;   Binswanger Disease;   Binswanger Encephalopathy;   Binswanger's Disease;   Binswanger's Encephalopathy;   Binswangers Disease;   Chronic Progressive Subcortical Encephalopathy;   Encephalopathy, Binswangers;   Multi Infarct Dementia;   Subcortical Arteriosclerotic Encephalopathies;   Subcortical Arteriosclerotic Encephalopathy;   Subcortical Leukoencephalopathies;   Subcortical Leukoencephalopathy;   Subcortical Vascular Dementia;   Subcortical Vascular Dementias;   acute onset vascular dementia;   multifocal dementia;   vascular dementias
 primary_id: MESH:D015140
 alt_id: RDO:0006843
 xref: ICD10CM:F01;   ICD10CM:F01.5;   ICD9CM:290.4;   NCI:C34522;   NCI:C34525
For additional species annotation, visit the Alliance of Genome Resources.


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vascular dementia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP5F1A ATP synthase F1 subunit alpha JBrowse link 18 46,080,248 46,104,233 RGD:14696801
G AVP arginine vasopressin JBrowse link 20 3,082,556 3,093,521 RGD:2303174
G BDNF brain derived neurotrophic factor JBrowse link 11 27,654,893 27,722,030 RGD:10059369
G CDK5 cyclin dependent kinase 5 JBrowse link 7 151,053,815 151,057,897 RGD:13792766
G EIF4E eukaryotic translation initiation factor 4E JBrowse link 4 98,871,684 98,930,637 RGD:10401142
G EPO erythropoietin JBrowse link 7 100,720,468 100,723,700 RGD:10400891
G FGFR1 fibroblast growth factor receptor 1 JBrowse link 8 38,411,138 38,468,834 RGD:10402076
G FLT1 fms related receptor tyrosine kinase 1 JBrowse link 13 28,300,346 28,495,128 RGD:10402076
G GCLM glutamate-cysteine ligase modifier subunit JBrowse link 1 93,885,199 93,910,370 RGD:10402374
G GPX1 glutathione peroxidase 1 JBrowse link 3 49,357,171 49,358,600 RGD:11352822
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 9 137,139,092 137,168,759 RGD:13792687
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 16 9,753,404 10,182,928 RGD:13792687
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 12 13,537,337 13,982,012 RGD:13792687
G GSK3B glycogen synthase kinase 3 beta JBrowse link 3 119,821,321 120,095,823 RGD:13792766
G HSPA1A heat shock protein family A (Hsp70) member 1A JBrowse link 6 31,815,543 31,817,942 RGD:10402403
G IGF1 insulin like growth factor 1 JBrowse link 12 102,395,860 102,481,839 RGD:1598446
RGD:10045864
G IGF1R insulin like growth factor 1 receptor JBrowse link 15 98,648,539 98,964,530 RGD:10045873
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:1626633
G LPA lipoprotein(a) JBrowse link 6 160,531,482 160,664,275 RGD:5509891
G MAPT microtubule associated protein tau JBrowse link 17 45,894,382 46,028,334 RGD:13792766
G MMP2 matrix metallopeptidase 2 JBrowse link 16 55,478,830 55,506,691 RGD:1582624
G MTOR mechanistic target of rapamycin kinase JBrowse link 1 11,106,535 11,273,497 RGD:10401142
G PON2 paraoxonase 2 JBrowse link 7 95,404,862 95,435,072 RGD:1580219
G RPGRIP1L RPGRIP1 like JBrowse link 16 53,598,153 53,703,938 RGD:13204815
G RPS6 ribosomal protein S6 JBrowse link 9 19,375,715 19,380,236 RGD:11041644
G SDHAF1 succinate dehydrogenase complex assembly factor 1 JBrowse link 19 35,995,188 35,996,312 RGD:11554173
G SNCA synuclein alpha JBrowse link 4 89,724,099 89,838,324 RGD:6478792
G SNCG synuclein gamma JBrowse link 10 86,955,759 86,963,260 RGD:6478792
G SREBF2 sterol regulatory element binding transcription factor 2 JBrowse link 22 41,833,105 41,907,308 RGD:1581412
G SST somatostatin JBrowse link 3 187,668,912 187,670,394 RGD:2303174
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:13825254
G TP53 tumor protein p53 JBrowse link 17 7,668,402 7,687,550 RGD:2290557
CADASIL term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HTRA1 HtrA serine peptidase 1 JBrowse link 10 122,461,553 122,514,907 RGD:11554173
G NOTCH3 notch receptor 3 JBrowse link 19 15,159,038 15,200,995 RGD:11554173
CADASIL 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MIR6795 microRNA 6795 JBrowse link 19 15,179,283 15,179,350 RGD:8554872
G NOTCH3 notch receptor 3 JBrowse link 19 15,159,038 15,200,995 RGD:7240710
RGD:8554872
CADASIL 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HTRA1 HtrA serine peptidase 1 JBrowse link 10 122,461,553 122,514,907 RGD:8554872
RGD:7240710
Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARMS2 age-related maculopathy susceptibility 2 JBrowse link 10 122,454,653 122,457,352 RGD:8554872
G HTRA1 HtrA serine peptidase 1 JBrowse link 10 122,461,553 122,514,907 RGD:8554872
RGD:7240710
Multi-Infarct Dementia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APP amyloid beta precursor protein JBrowse link 21 25,880,550 26,171,128 RGD:10054257
G BAX BCL2 associated X, apoptosis regulator JBrowse link 19 48,954,825 48,961,798 RGD:10054050
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:10054050
G G6PD glucose-6-phosphate dehydrogenase JBrowse link X 154,531,390 154,547,569 RGD:10449132
G IL2 interleukin 2 JBrowse link 4 122,451,470 122,456,725 RGD:10047081

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17602
    Diseases of the Aged 1090
      dementia 672
        vascular dementia 41
          CADASIL + 4
          Multi-Infarct Dementia 5
Path 2
Term Annotations click to browse term
  disease 17602
    disease of anatomical entity 16224
      nervous system disease 12490
        central nervous system disease 10564
          brain disease 9753
            disease of mental health 7298
              cognitive disorder 2420
                dementia 672
                  vascular dementia 41
                    CADASIL + 4
                    Multi-Infarct Dementia 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.