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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular dementia
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Accession:DOID:8725 term browser browse the term
Definition:An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)
Synonyms:exact_synonym: Arteriosclerotic Dementia;   Arteriosclerotic Dementias;   Binswanger Disease;   Binswanger Encephalopathy;   Binswanger's Disease;   Binswanger's Encephalopathy;   Binswangers Disease;   Chronic Progressive Subcortical Encephalopathy;   Encephalopathy, Binswangers;   Multi Infarct Dementia;   Subcortical Arteriosclerotic Encephalopathies;   Subcortical Arteriosclerotic Encephalopathy;   Subcortical Leukoencephalopathies;   Subcortical Leukoencephalopathy;   Subcortical Vascular Dementia;   Subcortical Vascular Dementias;   acute onset vascular dementia;   multifocal dementia;   vascular dementias
 primary_id: MESH:D015140
 alt_id: RDO:0006843
 xref: ICD10CM:F01;   ICD10CM:F01.5;   ICD9CM:290.4;   NCI:C34522;   NCI:C34525
For additional species annotation, visit the Alliance of Genome Resources.


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vascular dementia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 JBrowse link 18 77,773,768 77,782,869 RGD:14696801
G Avp arginine vasopressin JBrowse link 2 130,580,620 130,582,588 RGD:2303174
G Bdnf brain derived neurotrophic factor JBrowse link 2 109,674,700 109,727,043 RGD:10059369
G Cdk5 cyclin-dependent kinase 5 JBrowse link 5 24,407,597 24,423,587 RGD:13792766
G Eif4e eukaryotic translation initiation factor 4E JBrowse link 3 138,526,191 138,559,696 RGD:10401142
G Epo erythropoietin JBrowse link 5 137,483,020 137,485,816 RGD:10400891
G Fgfr1 fibroblast growth factor receptor 1 JBrowse link 8 25,518,759 25,575,718 RGD:10402076
G Flt1 FMS-like tyrosine kinase 1 JBrowse link 5 147,561,604 147,726,438 RGD:10402076
G Gclm glutamate-cysteine ligase, modifier subunit JBrowse link 3 122,245,487 122,267,215 RGD:10402374
G Gpx1 glutathione peroxidase 1 JBrowse link 9 108,339,080 108,340,342 RGD:11352822
G Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) JBrowse link 2 25,291,177 25,319,253 RGD:13792687
G Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) JBrowse link 16 9,567,901 9,996,083 RGD:13792687
G Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) JBrowse link 6 135,713,221 136,173,615 RGD:13792687
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 16 38,089,001 38,246,084 RGD:13792766
G Hspa1a heat shock protein 1A JBrowse link 17 34,969,359 34,972,156 RGD:10402403
G Igf1 insulin-like growth factor 1 JBrowse link 10 87,858,265 87,937,047 RGD:1598446
RGD:10045864
G Igf1r insulin-like growth factor I receptor JBrowse link 7 67,952,257 68,233,668 RGD:10045873
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:1626633
G Mapt microtubule-associated protein tau JBrowse link 11 104,229,409 104,332,090 RGD:13792766
G Mmp2 matrix metallopeptidase 2 JBrowse link 8 92,827,290 92,853,421 RGD:1582624
G Mtor mechanistic target of rapamycin kinase JBrowse link 4 148,448,582 148,557,685 RGD:10401142
G Pon2 paraoxonase 2 JBrowse link 6 5,264,620 5,298,345 RGD:1580219
G Rpgrip1l Rpgrip1-like JBrowse link 8 91,217,030 91,313,291 RGD:13204815
G Rps6 ribosomal protein S6 JBrowse link 4 86,854,099 86,857,367 RGD:11041644
G Sdhaf1 succinate dehydrogenase complex assembly factor 1 JBrowse link 7 30,321,409 30,322,375 RGD:11554173
G Snca synuclein, alpha JBrowse link 6 60,731,573 60,829,855 RGD:6478792
G Sncg synuclein, gamma JBrowse link 14 34,370,274 34,374,669 RGD:6478792
G Srebf2 sterol regulatory element binding factor 2 JBrowse link 15 82,147,269 82,205,379 RGD:1581412
G Sst somatostatin JBrowse link 16 23,889,573 23,891,342 RGD:2303174
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:13825254
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:2290557
CADASIL term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Htra1 HtrA serine peptidase 1 JBrowse link 7 130,936,203 130,985,658 RGD:11554173
G Notch3 notch 3 JBrowse link 17 32,120,820 32,166,896 RGD:8554872
RGD:11554173
CADASIL 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Notch3 notch 3 JBrowse link 17 32,120,820 32,166,896 RGD:7240710
RGD:8554872
RGD:13592920
CADASIL 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Htra1 HtrA serine peptidase 1 JBrowse link 7 130,936,203 130,985,658 RGD:8554872
RGD:7240710
Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Htra1 HtrA serine peptidase 1 JBrowse link 7 130,936,203 130,985,658 RGD:7240710
RGD:8554872
Multi-Infarct Dementia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G App amyloid beta (A4) precursor protein JBrowse link 16 84,952,666 85,175,255 RGD:10054257
G Bax BCL2-associated X protein JBrowse link 7 45,461,695 45,466,903 RGD:10054050
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:10054050
G G6pdx glucose-6-phosphate dehydrogenase X-linked JBrowse link X 74,409,483 74,428,880 RGD:10449132
G Il2 interleukin 2 JBrowse link 3 37,120,713 37,125,954 RGD:10047081

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12617
    Diseases of the Aged 980
      dementia 614
        vascular dementia 38
          CADASIL + 2
          Multi-Infarct Dementia 5
Path 2
Term Annotations click to browse term
  disease 12617
    disease of anatomical entity 12180
      nervous system disease 9644
        central nervous system disease 7959
          brain disease 7328
            disease of mental health 5440
              cognitive disorder 1735
                dementia 614
                  vascular dementia 38
                    CADASIL + 2
                    Multi-Infarct Dementia 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.