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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular dementia
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Accession:DOID:8725 term browser browse the term
Definition:An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)
Synonyms:exact_synonym: Arteriosclerotic Dementia;   Arteriosclerotic Dementias;   Binswanger Disease;   Binswanger Encephalopathy;   Binswanger's Disease;   Binswanger's Encephalopathy;   Binswangers Disease;   Chronic Progressive Subcortical Encephalopathy;   Encephalopathy, Binswangers;   Multi Infarct Dementia;   Subcortical Arteriosclerotic Encephalopathies;   Subcortical Arteriosclerotic Encephalopathy;   Subcortical Leukoencephalopathies;   Subcortical Leukoencephalopathy;   Subcortical Vascular Dementia;   Subcortical Vascular Dementias;   acute onset vascular dementia;   multifocal dementia;   vascular dementias
 primary_id: MESH:D015140
 alt_id: RDO:0006843
 xref: ICD10CM:F01;   ICD10CM:F01.5;   ICD9CM:290.4;   NCI:C34522;   NCI:C34525
For additional species annotation, visit the Alliance of Genome Resources.


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vascular dementia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP5F1A ATP synthase F1 subunit alpha JBrowse link 1 95,738,789 95,750,835 RGD:9068941
G AVP arginine vasopressin JBrowse link 17 32,581,234 32,583,145 RGD:9068941
G BDNF brain derived neurotrophic factor JBrowse link 2 32,623,668 32,679,293 RGD:9068941
G CDK5 cyclin dependent kinase 5 JBrowse link 18 6,166,914 6,171,157 RGD:9068941
G EIF4E eukaryotic translation initiation factor 4E JBrowse link 8 121,409,633 121,464,467 RGD:9068941
G EPO erythropoietin JBrowse link 3 8,620,508 8,622,936 RGD:9068941
G FGFR1 fibroblast growth factor receptor 1 JBrowse link 15 48,053,895 48,106,634 RGD:9068941
G FLT1 fms related receptor tyrosine kinase 1 JBrowse link 11 5,620,698 5,797,095 RGD:9068941
G GCLM glutamate-cysteine ligase modifier subunit JBrowse link 4 123,371,198 123,390,130 RGD:9068941
G GPX1 glutathione peroxidase 1 JBrowse link 13 31,916,269 31,917,337 RGD:9068941
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 RGD:9068941
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 3 32,749,329 33,149,350 RGD:9068941
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 5 58,477,862 58,948,735 RGD:9068941
G GSK3B glycogen synthase kinase 3 beta JBrowse link 13 140,136,109 140,370,197 RGD:9068941
G IGF1 insulin like growth factor 1 JBrowse link 5 81,762,027 81,909,253 RGD:9068941
G IGF1R insulin like growth factor 1 receptor JBrowse link 1 137,383,623 137,691,038 RGD:9068941
G LOC110258578 interleukin-1 beta-like RGD:9068941
G MAPT microtubule associated protein tau JBrowse link 12 17,098,259 17,211,483 RGD:9068941
G MMP2 matrix metallopeptidase 2 JBrowse link 6 30,059,247 30,087,031 RGD:9068941
G MTOR mechanistic target of rapamycin kinase JBrowse link 6 71,286,989 71,412,913 RGD:9068941
G PON2 paraoxonase 2 JBrowse link 9 75,027,270 75,051,441 RGD:9068941
G RPGRIP1L RPGRIP1 like JBrowse link 6 31,564,937 31,660,540 RGD:9068941
G RPS6 ribosomal protein S6 JBrowse link 1 203,444,360 203,447,643 RGD:9068941
G SDHAF1 succinate dehydrogenase complex assembly factor 1 JBrowse link 6 45,374,714 45,376,346 RGD:9068941
G SNCA synuclein alpha JBrowse link 8 129,247,724 129,388,307 RGD:9068941
G SNCG synuclein gamma JBrowse link 14 87,916,353 87,922,111 RGD:9068941
G SREBF2 sterol regulatory element binding transcription factor 2 JBrowse link 5 6,719,484 6,784,724 RGD:9068941
G SST somatostatin JBrowse link 13 125,337,560 125,338,742 RGD:9068941
G TNF tumor necrosis factor JBrowse link 7 23,699,635 23,702,393 RGD:9068941
G TP53 tumor protein p53 JBrowse link 12 52,939,643 52,953,786 RGD:9068941
CADASIL term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HTRA1 HtrA serine peptidase 1 JBrowse link 14 132,043,044 132,103,590 RGD:9068941
G NOTCH3 notch receptor 3 JBrowse link 2 62,364,507 62,402,348 RGD:9068941
CADASIL 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NOTCH3 notch receptor 3 JBrowse link 2 62,364,507 62,402,348 RGD:7240710
CADASIL 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HTRA1 HtrA serine peptidase 1 JBrowse link 14 132,043,044 132,103,590 RGD:7240710
Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HTRA1 HtrA serine peptidase 1 JBrowse link 14 132,043,044 132,103,590 RGD:7240710
Multi-Infarct Dementia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APP amyloid beta precursor protein JBrowse link 13 189,434,854 189,716,120 RGD:9068941
G BAX BCL2 associated X, apoptosis regulator JBrowse link 6 54,222,341 54,228,150 RGD:9068941
G BCL2 BCL2 apoptosis regulator JBrowse link 1 158,337,403 158,518,214 RGD:9068941
G G6PD glucose-6-phosphate dehydrogenase JBrowse link X 125,029,147 125,041,040 RGD:9068941
G IL2 interleukin 2 JBrowse link 8 101,640,938 101,645,683 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12518
    Diseases of the Aged 964
      dementia 619
        vascular dementia 37
          CADASIL + 2
          Multi-Infarct Dementia 5
Path 2
Term Annotations click to browse term
  disease 12518
    disease of anatomical entity 12073
      nervous system disease 9798
        central nervous system disease 8211
          brain disease 7544
            disease of mental health 5424
              cognitive disorder 1684
                dementia 619
                  vascular dementia 37
                    CADASIL + 2
                    Multi-Infarct Dementia 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.