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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:fascioliasis
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Accession:DOID:885 term browser browse the term
Definition:Liver disease caused by infections with parasitic flukes of the genus FASCIOLA, such as FASCIOLA HEPATICA.
Synonyms:exact_synonym: Fasciola hepatica infection;   Fascioliases;   Infection by Fasciola;   Liver flukes;   Sheep liver fluke infection
 primary_id: MESH:D005211
 alt_id: RDO:0005574
 xref: GARD:6428;   ICD10CM:B66.3;   ICD9CM:121.3;   NCI:C128387
For additional species annotation, visit the Alliance of Genome Resources.


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fascioliasis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsb cathepsin B IEP protein:decreased activity:liver (rat) RGD PMID:19696938 RGD:2315504 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Glud1 glutamate dehydrogenase 1 IEP protein:increased expression:serum RGD PMID:10431747 RGD:6484593 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16108
    disease by infectious agent 1748
      parasitic infectious disease 221
        Parasitic Liver Diseases 18
          fascioliasis 2
Path 2
Term Annotations click to browse term
  disease 16108
    disease of anatomical entity 15356
      gastrointestinal system disease 4673
        hepatobiliary disease 0
          liver disease 2394
            Parasitic Liver Diseases 18
              fascioliasis 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.