ONTOLOGY REPORT - ANNOTATIONS


Term:Graves Ophthalmopathy
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Accession:DOID:9000008 term browser browse the term
Definition:An autoimmune disorder of the EYE, occurring in patients with Graves disease. Subtypes include congestive (inflammation of the orbital connective tissue), myopathic (swelling and dysfunction of the extraocular muscles), and mixed congestive-myopathic ophthalmopathy.
Synonyms:exact_synonym: Congestive Ophthalmopathies;   Congestive Ophthalmopathy;   Dysthyroid Ophthalmopathies;   Dysthyroid Ophthalmopathy;   Edematous Ophthalmopathies;   Edematous Ophthalmopathy;   Infiltrative Ophthalmopathies;   Infiltrative Ophthalmopathy;   Myopathic Ophthalmopathies;   Myopathic Ophthalmopathy;   Thyroid Associated Ophthalmopathies;   Thyroid Associated Ophthalmopathy;   Thyroid Eye Disease
 narrow_synonym: Graves' Orbitopathy;   Thyroid-Associated Orbitopathy
 primary_id: MESH:D049970;   RDO:0007562
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Graves Ophthalmopathy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:9071200
RGD:9086875
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8549459
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:7421511
RGD:7421521
RGD:7421523
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:8158124
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:7794734
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:8548854
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:7364859
RGD:7365083
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:8655878
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:7794734
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:7387296
RGD:8549808
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:8662939
G Il23r interleukin 23 receptor JBrowse link 4 98,203,788 98,306,729 RGD:7421521
RGD:8549554
G Il3 interleukin 3 JBrowse link 10 39,620,535 39,622,973 RGD:5686901
G Kif1a kinesin family member 1A JBrowse link 9 100,171,851 100,253,626 RGD:12911230
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:8552818
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:11554173
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 JBrowse link 2 206,342,066 206,390,348 RGD:7829763
G Scd stearoyl-CoA desaturase JBrowse link 1 264,159,966 264,173,061 RGD:11554173
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:8547756
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:7365073
RGD:12904066
RGD:7794734
G Tshr thyroid stimulating hormone receptor JBrowse link 6 115,170,290 115,306,871 RGD:8548662
RGD:8548673

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14823
    disease of anatomical entity 13997
      endocrine system disease 4666
        autoimmune disease of endocrine system 97
          Graves' disease 59
            Graves Ophthalmopathy 21
Path 2
Term Annotations click to browse term
  disease 14823
    disease of anatomical entity 13997
      nervous system disease 9111
        sensory system disease 4244
          eye and adnexa disease 1985
            eye disease 1985
              orbital disease 62
                exophthalmos 60
                  Graves' disease 59
                    Graves Ophthalmopathy 21
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.