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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Systemic Inflammatory Response Syndrome
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Accession:DOID:9000169 term browser browse the term
Definition:A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees C or HYPOTHERMIA <36 degrees C; (2) TACHYCARDIA >90 beat/minute; (3) tachypnea >24 breaths/minute; (4) LEUKOCYTOSIS >12,000 cells/cubic mm or 10% immature forms. While usually related to infection, SIRS can also be associated with noninfectious insults such as TRAUMA; BURNS; or PANCREATITIS. If infection is involved, a patient with SIRS is said to have SEPSIS.
Synonyms:exact_synonym: Sepsis Syndrome;   Sepsis Syndromes
 primary_id: MESH:D018746
For additional species annotation, visit the Alliance of Genome Resources.


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Systemic Inflammatory Response Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin ISO associated with infant, premature;protein:increased expression:urine RGD PMID:19527385 RGD:6482709 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Cfh complement factor H ISO RGD PMID:20351616 RGD:5684556 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
JBrowse link
G F3 coagulation factor III, tissue factor ISO RGD PMID:9366751 RGD:11341681 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Il1b interleukin 1 beta ISO RGD PMID:22253906 RGD:7175262 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Mir223 microRNA 223 ISO RNA:increased expression:plasma: RGD PMID:24680405 RGD:21408586 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Nos2 nitric oxide synthase 2 IEP protein:increased expression:ileum, liver (rat) RGD PMID:21975127 RGD:5508740 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Plaur plasminogen activator, urokinase receptor disease_progression ISO RGD PMID:18197443 RGD:6484114 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Thbd thrombomodulin ISO protein:increased expression:blood RGD PMID:15187749 RGD:5685024 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B IEP mRNA, protein:increased expression:carotid body, jugular ganglion, nodose ganglion (rat) RGD PMID:21195213 RGD:5130879 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Vdr vitamin D receptor susceptibility ISO associated with pneumonia; DNA:SNP: :rs2239185(human) RGD PMID:25367052 RGD:11074745 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
Bacteremia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 ISO associated with Febrile Neutropenia;protein:increased expression:serum (human) RGD PMID:22584776 RGD:11528568 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cfh complement factor H ISO associated with Meningococcal Infections; RGD PMID:22104107 RGD:7364945 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
JBrowse link
G Cish cytokine inducible SH2-containing protein susceptibility ISO ClinVar Annotator: match by OMIM:614383
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:20484391 NCBI chr 8:116,054,547...116,059,494
Ensembl chr 8:116,054,465...116,060,723
JBrowse link
G Cpb2 carboxypeptidase B2 IEP protein:decreased activity:plasma RGD PMID:17911187 RGD:2313646 NCBI chr15:57,290,849...57,339,762
Ensembl chr15:57,290,849...57,339,760
JBrowse link
G Crp C-reactive protein ISO protein:increased expression:serum: RGD PMID:18443549 RGD:9491402 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csf2 colony stimulating factor 2 treatment ISO RGD PMID:2192004 RGD:10449532 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa ISO associated with Pneumonia;DNA:SNP: :p.H131R (rs1801274) (human) RGD PMID:21317643 RGD:5147986 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase severity ISO RGD PMID:11565076 RGD:5508478 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO mRNA:increased expression:lung,thymus,spleen: RGD PMID:24891762 RGD:11354979 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il17a interleukin 17A ISO associated with Respiratory Distress Syndrome, Adult; protein:increased expression:serum RGD PMID:21062445 RGD:5128683 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 ISO ClinVar Annotator: match by term: Bacteremia, susceptibility to, 2 ClinVar PMID:20484391 NCBI chr 8:116,012,126...116,046,012
Ensembl chr 8:116,012,121...116,045,954
JBrowse link
G Mbl2 mannose binding lectin 2 treatment ISO associated with Multiple Myeloma:DNA:polymorphism:exon: RGD PMID:16953214 RGD:11530047 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 severity ISO associated with Staphylococcal Infections; RGD PMID:24086711 RGD:13204726 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:1430592 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plaur plasminogen activator, urokinase receptor severity ISO RGD PMID:21332843 RGD:6483799 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO RGD PMID:2679067 RGD:11035251 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Sod2 superoxide dismutase 2 ISO mRNA:increased expression:liver: RGD PMID:24253037 RGD:26923958 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tirap TIR domain containing adaptor protein ISO ClinVar Annotator: match by term: BACTEREMIA, RESISTANCE TO
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
PMID:16991088, PMID:17322885, PMID:18305471 NCBI chr 8:36,382,029...36,399,625
Ensembl chr 8:36,385,353...36,388,224
JBrowse link
G Tlr4 toll-like receptor 4 susceptibility ISO DNA:polymorphisms:cds:p.D299G, T399I (human) RGD PMID:18180796 RGD:4144194 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
cerebral malaria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp4 aquaporin 4 disease_progression ISO protein:increased expression:astrocyte: RGD PMID:21904632 RGD:8698661 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Cast calpastatin ISO protein:increased express:brain RGD PMID:16236382 RGD:5509817 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cd36 CD36 molecule ISO RGD PMID:17367535 RGD:6893527 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Jak3 Janus kinase 3 ISO RGD PMID:22363534 RGD:11531103 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668
JBrowse link
G Lta lymphotoxin alpha ISO RGD PMID:12021316 RGD:10449455 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO RGD PMID:12228317 RGD:5131158 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
Endotoxemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 IEP RGD PMID:9828229 RGD:1598596 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A IEP mRNA:decreased expression:liver (rat) RGD PMID:26977098 RGD:11041000 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:20300455, PMID:9828229 RGD:1598596 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 IEP RGD PMID:16572733 RGD:1598611 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 IEP RGD PMID:17285300 RGD:2301914 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Ace angiotensin I converting enzyme IEP associated with Hemorrhage;protein:decreased activity:plasma (rat) RGD PMID:3028670 RGD:8142370 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ache acetylcholinesterase ISO RGD PMID:17657467 RGD:5688055 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 IEP RGD PMID:11680626 RGD:1598729 NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 IEP protein:increased expression:plasma, spleen RGD PMID:23025351 RGD:9681752 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing IEP associated with Obesity RGD PMID:23838384 RGD:8695926 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adipor2 adiponectin receptor 2 severity IEP associated with obesity;mRNA:decreased expression:liver (rat) RGD PMID:23838384 RGD:8695926 NCBI chr 4:151,412,135...151,480,108
Ensembl chr 4:151,414,684...151,428,894
JBrowse link
G Adra2a adrenoceptor alpha 2A onset IEP mRNA:increased expression:spleen RGD PMID:20302880 RGD:6480487 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Agtr2 angiotensin II receptor, type 2 IEP protein:decreased expression:kidney RGD PMID:16725227 RGD:6903849 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Akp3 alkaline phosphatase 3, intestine, not Mn requiring ISO RGD PMID:23569246 RGD:14349049 NCBI chr 9:94,228,960...94,232,001
Ensembl chr 9:94,228,960...94,232,001
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A IEP RGD PMID:16930621 RGD:1599054 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15328337 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Apoa1 apolipoprotein A1 treatment ISO
IDA
RGD PMID:18593575, PMID:23227448 RGD:7241573, RGD:7241868 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apob apolipoprotein B IEP RGD PMID:16719989 RGD:1599165 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoe apolipoprotein E ISO rat model treated with human protein RGD PMID:9153287 RGD:6904216 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Asl argininosuccinate lyase IEP RGD PMID:10652239 RGD:1599265 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Ass1 argininosuccinate synthase 1 IEP RGD PMID:10652239 RGD:1599265 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Atf2 activating transcription factor 2 treatment IEP
IDA
protein:increased expression, increased activity:small intestine mucosa RGD PMID:21641970, PMID:24312512 RGD:5135029, RGD:10047418 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16741687 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495
JBrowse link
G Bax BCL2 associated X, apoptosis regulator IEP mRNA:increased expression:diaphragm RGD PMID:23940949 RGD:10054120 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bche butyrylcholinesterase ISO RGD PMID:17657467 RGD:5688055 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator IEP mRNA:decreased expression:diaphragm RGD PMID:23940949 RGD:10054120 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G C5ar1 complement C5a receptor 1 IEP mRNA:increased expression:lung RGD PMID:9272704 RGD:70679 NCBI chr 1:78,186,777...78,195,132
Ensembl chr 1:78,186,776...78,195,328
JBrowse link
G Casp1 caspase 1 IMP RGD PMID:17384935 RGD:2315892 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 IEP mRNA:increased expression:diaphragm RGD PMID:23940949 RGD:10054120 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 ISO RGD PMID:19168786 RGD:5684539 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp9 caspase 9 treatment IEP RGD PMID:23214195 RGD:10400903 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP protein:increased expression:plasma RGD PMID:19060786 RGD:2307004 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP protein:increased expression:plasma RGD PMID:16215387 RGD:2307171 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO RGD PMID:17016504 RGD:5688178 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Cd14 CD14 molecule IEP protein:increased expression:liver, endothelial cell of sinusoid RGD PMID:12046090 RGD:724637 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd40 CD40 molecule ISO protein:decreased nitrosylation:macrophage RGD PMID:20473113 RGD:5490974 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16741687 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274
JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:9514298 RGD:11039535 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IEP protein:increased expression:atrium endocardium RGD PMID:19282612 RGD:4891965 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO mRNA:increased expression:multiple organs RGD PMID:9766630 RGD:5135254 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO mRNA:increased expression:multiple organs RGD PMID:9766630 RGD:5135254 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 ISO mRNA:increased expression:multiple organs RGD PMID:9766630 RGD:5135254 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Edn1 endothelin 1 IEP mRNA, protein:increased expression:liver (rat) RGD PMID:11206318 RGD:8662297 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ep300 E1A binding protein p300 IEP associated with Kidney Reperfusion Injury; protein:altered localization:kidney (rat) RGD PMID:23936185 RGD:7257563 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:19154430 RGD:5688360 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:23214195 RGD:10400903 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G F12 coagulation factor XII IEP RGD PMID:11092686 RGD:7394782 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420
JBrowse link
G F2 coagulation factor II severity
treatment
IDA
ISO
IEP
associated with liver cirrhosis;protein:increased expression:plasma (human) RGD PMID:21396682, PMID:9863491, PMID:25396762, PMID:22227956, PMID:20519137 RGD:5147765, RGD:14401592, RGD:10449434, RGD:6893482, RGD:5147779 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F3 coagulation factor III, tissue factor treatment IDA
ISO
associated with Protein C Deficiency RGD PMID:21396682, PMID:20858853, PMID:8956768 RGD:5147765, RGD:11341685, RGD:11340208 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G F5 coagulation factor V IEP RGD PMID:11092686 RGD:7394782 NCBI chr13:82,479,997...82,535,540
Ensembl chr13:82,479,998...82,535,534
JBrowse link
G F7 coagulation factor VII treatment IEP
ISO
RGD PMID:11092686, PMID:16378835 RGD:7394782, RGD:11041650 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G F8 coagulation factor VIII IEP RGD PMID:11092686 RGD:7394782 NCBI chr18:367,862...399,242
Ensembl chr18:367,862...399,242
JBrowse link
G Fas Fas cell surface death receptor IEP mRNA, protein:increased expression:spleen (rat) RGD PMID:20428798 RGD:8662930 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fga fibrinogen alpha chain treatment IDA RGD PMID:19295478 RGD:11040925 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Foxp3 forkhead box P3 IEP protein:increased expression:intestinal mucosa RGD PMID:19998507 RGD:38455980 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Gfer growth factor, augmenter of liver regeneration IEP RGD PMID:23073658 RGD:9685733 NCBI chr10:14,059,347...14,061,703
Ensembl chr10:14,059,347...14,061,703
JBrowse link
G Ghr growth hormone receptor IEP mRNA:decreased expression:liver RGD PMID:12654216, PMID:12217886 RGD:2307380, RGD:625688 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP RGD PMID:25469663 RGD:10401928 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hmgb1 high mobility group box 1 IEP protein:increased expression:heart, serum RGD PMID:18503231 RGD:10402065 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 treatment IEP RGD PMID:21396999 RGD:10755715 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsf1 heat shock transcription factor 1 treatment IDA RGD PMID:25571843 RGD:10402404 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16741687 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IEP
ISO
mRNA, protein:increased expression:medulla oblongata
CTD Direct Evidence: marker/mechanism
CTD PMID:16741687, PMID:16675490 RGD:1624232 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP protein:increased expression:lung (rat) RGD PMID:19776691 RGD:4145502 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma IEP protein:increased expression:serum: RGD PMID:9195172 RGD:10755747 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 IEP mRNA, protein:decreased expression:liver, serum RGD PMID:18492809, PMID:12217886 RGD:10402757, RGD:625688 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit IEP RGD PMID:12217886 RGD:625688 NCBI chr10:14,240,308...14,243,554
Ensembl chr10:14,240,219...14,243,597
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 IEP RGD PMID:12217886 RGD:625688 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 IEP mRNA, protein:decreased expression:liver, serum RGD PMID:18492809 RGD:10402757 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 IEP RGD PMID:12217886 RGD:625688 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Il10 interleukin 10 treatment IEP
ISO
protein:increased expression:plasma RGD PMID:19302852, PMID:27943364, PMID:28664613 RGD:2311055, RGD:14975170, RGD:14975137 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il13 interleukin 13 treatment ISO RGD PMID:10674721 RGD:8549626 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il1a interleukin 1 alpha ISO
IEP
protein:increased expression:plasma RGD PMID:9636192, PMID:22426124 RGD:6907109, RGD:7794786 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta IEP protein:increased expression:plasma RGD PMID:17201737 RGD:1626625 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment IEP
ISO
mRNA:increased expression:lung, spleen, liver (rat) RGD PMID:1385928, PMID:8855299 RGD:8551846, RGD:11522760 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il6 interleukin 6 IDA
IEP
associated with Diabetes Mellitus, Experimental; Protein:increased expression:extracellular space (rat)
protein:increased expression:serum (rat)
RGD PMID:19449282, PMID:22227956, PMID:21396682 RGD:2307179, RGD:6893482, RGD:5147765 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO mRNA, protein:increased expression:blood (human) RGD PMID:17982103 RGD:36049802 NCBI chr 7:64,922,830...64,982,224
Ensembl chr 7:64,923,615...64,982,281
JBrowse link
G Irs1 insulin receptor substrate 1 ISO protein:increased tyrosine nitration, decreased tyrosine phosphorylation:skeletal muscle RGD PMID:21206533 RGD:6483008 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Itga2b integrin subunit alpha 2b IMP RGD PMID:15280099 RGD:2316360 NCBI chr10:90,397,960...90,416,550
Ensembl chr10:90,398,132...90,415,070
JBrowse link
G Itgb3 integrin subunit beta 3 IMP RGD PMID:15280099 RGD:2316360 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 ISO RGD PMID:22609006 RGD:6892951 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Lbp lipopolysaccharide binding protein treatment IEP
ISO
mRNA:increased expression:hepatocyte RGD PMID:8418776, PMID:8593028, PMID:16307218 RGD:9685191, RGD:9685196, RGD:9685193 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Map2 microtubule-associated protein 2 ISO mRNA, protein:decreased expression:neuron RGD PMID:21421895 RGD:6483086 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Mapk14 mitogen activated protein kinase 14 treatment IEP
IDA
protein:increased activity:small intestine mucosa RGD PMID:21641970, PMID:24312512 RGD:5135029, RGD:10047418 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mc4r melanocortin 4 receptor IEP mRNA:increased expression:paraventricular nucleus (rat) RGD PMID:21343543 RGD:6484214 NCBI chr18:62,612,838...62,614,725
Ensembl chr18:62,612,838...62,614,725
JBrowse link
G Mif macrophage migration inhibitory factor IEP protein:increased expression:plasma RGD PMID:16601957 RGD:1641983 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mir155 microRNA 155 treatment ISO associated with familial hyperlipidemia RGD PMID:28970282, PMID:28264607, PMID:29079998, PMID:29979224 RGD:21079445, RGD:24922204, RGD:21081539, RGD:21081538 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mme membrane metallo-endopeptidase severity IMP RGD PMID:11078421 RGD:13801040 NCBI chr 2:153,799,203...153,880,910
Ensembl chr 2:153,803,349...153,880,738
JBrowse link
G Mmp3 matrix metallopeptidase 3 IEP RGD PMID:17083784 RGD:2290426 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mt2A metallothionein 2A IEP mRNA:increased expression:liver (rat) RGD PMID:22100509 RGD:6483852 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mt3 metallothionein 3 IEP RGD PMID:12135776 RGD:10412330 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming IEP RGD PMID:19099858 RGD:7349370 NCBI chr 1:214,663,929...214,693,197 JBrowse link
G Myh6 myosin heavy chain 6 IEP RGD PMID:7874842 RGD:12792976 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Myh7 myosin heavy chain 7 IEP RGD PMID:7874842 RGD:12792976 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Nos2 nitric oxide synthase 2 IEP
ISO
IDA
mRNA, protein:increased expression:intestine
CTD Direct Evidence: marker/mechanism
CTD PMID:12620498, PMID:16787348, PMID:20519137 RGD:4891470, RGD:5147779 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 IEP protein:increased expression:aorta (rat) RGD PMID:10462376 RGD:7794732 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Npy neuropeptide Y treatment IDA RGD PMID:15342191 RGD:1580787 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IDA RGD PMID:15640646 RGD:4892561 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Otc ornithine carbamoyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16741687 NCBI chr  X:13,524,804...13,601,074
Ensembl chr  X:13,524,607...13,601,069
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 IEP RGD PMID:19268478, PMID:12217886 RGD:10427879, RGD:625688 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) IEP mRNA,protein:decreased expression,decreased activity:liver: RGD PMID:19268478 RGD:10427879 NCBI chr15:34,216,735...34,224,357
Ensembl chr15:34,216,833...34,224,193
JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 IEP RGD PMID:16337011 RGD:6483567 NCBI chr 2:91,450,162...91,497,091
Ensembl chr 2:91,450,162...91,497,091
JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 IEP RGD PMID:16337011 RGD:6483567 NCBI chr 3:137,618,891...137,923,385
Ensembl chr 3:137,618,898...137,925,605
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:22119535 RGD:6771174 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pgf placental growth factor ISO protein:increased expression:multiple RGD PMID:16702604 RGD:6483601 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
G Pla2g7 phospholipase A2 group VII IEP protein:increased expression: : RGD PMID:10748027 RGD:7248791 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Plat plasminogen activator, tissue type treatment ISO RGD PMID:9091588 RGD:11541073 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IEP protein:increased expression:small intestine mucosa RGD PMID:21641970 RGD:5135029 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 ISO mRNA:decreased expression:epididymal fat pad RGD PMID:20421294 RGD:6484543 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO protein:increased expression:liver, mitochondrion (mouse) RGD PMID:28615325 RGD:13432559 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:18205901, PMID:23170801 RGD:11100030, RGD:11100034 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091
JBrowse link
G Ptafr platelet-activating factor receptor treatment IMP RGD PMID:2178565 RGD:10041063 NCBI chr 5:150,746,284...150,775,675
Ensembl chr 5:150,754,021...150,775,672
JBrowse link
G Ptger4 prostaglandin E receptor 4 IEP protein:increased expression:paraventricular hypothalamic nucleus parvicellular division (rat) RGD PMID:11058222 RGD:10043329 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IEP RGD PMID:21641970 RGD:5135029 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO
IDA
IEP
RGD PMID:16457847, PMID:21396682, PMID:20519137, PMID:15995859 RGD:1599326, RGD:5147765, RGD:5147779, RGD:1599332 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Serpine1 serpin family E member 1 treatment IEP
IDA
RGD PMID:21396682, PMID:25396762 RGD:5147765, RGD:10449434 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serpinf1 serpin family F member 1 ISO protein:increased expression:plasma (human) RGD PMID:12386642 RGD:36174005 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
G Serping1 serpin family G member 1 treatment ISO RGD PMID:18652771 RGD:8661643 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078
JBrowse link
G Slc18a3 solute carrier family 18 member A3 IEP protein:decreased expression:parietal cortex RGD PMID:17306796 RGD:5686693 NCBI chr16:8,682,668...8,685,529
Ensembl chr16:8,682,669...8,685,529
JBrowse link
G Slc22a1 solute carrier family 22 member 1 treatment IDA RGD PMID:18313662 RGD:7243881 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a2 solute carrier family 22 member 2 treatment IDA RGD PMID:18313662 RGD:7243881 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc38a3 solute carrier family 38, member 3 IEP RGD PMID:20036385 RGD:9999227 NCBI chr 8:116,406,258...116,423,752
Ensembl chr 8:116,406,241...116,422,366
JBrowse link
G Slc38a5 solute carrier family 38, member 5 IEP RGD PMID:20036385 RGD:9999227 NCBI chr  X:14,963,919...14,972,675
Ensembl chr  X:14,963,921...14,972,675
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor IEP RGD PMID:25466948 RGD:9999425 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO mRNA:increased expression:liver, skeletal muscle RGD PMID:15169905 RGD:2298923 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Socs3 suppressor of cytokine signaling 3 ISO
IEP
mRNA:increased expression:liver, skeletal muscle RGD PMID:15169905, PMID:12217886 RGD:2298923, RGD:625688 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16741687 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sparc secreted protein acidic and cysteine rich IEP mRNA, protein:decreased expression:kidney RGD PMID:10703670 RGD:2300026 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Stat5b signal transducer and activator of transcription 5B IDA protein:decreased tyrosine phosphorylation:liver RGD PMID:17327369 RGD:1601383 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
G Tbxa2r thromboxane A2 receptor IDA
IMP
RGD PMID:15647606, PMID:2580129 RGD:1601450, RGD:11059531 NCBI chr 7:11,253,153...11,259,233
Ensembl chr 7:11,253,180...11,257,977
JBrowse link
G Tbxas1 thromboxane A synthase 1 IDA RGD PMID:15647606 RGD:1601450 NCBI chr 4:66,624,181...66,846,745
Ensembl chr 4:66,670,618...66,846,805
JBrowse link
G Tfpi tissue factor pathway inhibitor treatment ISO RGD PMID:17537762 RGD:11062086 NCBI chr 3:71,852,738...71,902,127
Ensembl chr 3:71,852,744...71,893,618
JBrowse link
G Thbd thrombomodulin IEP
ISO
mRNA:decreased expression:endothelial cell RGD PMID:12611420, PMID:20348393, PMID:19487933 RGD:1601652, RGD:5685037, RGD:5684988 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 IEP RGD PMID:17083784 RGD:2290426 NCBI chr 7:23,543,125...23,594,170
Ensembl chr 7:23,544,215...23,594,133
JBrowse link
G Tlr2 toll-like receptor 2 treatment IDA RGD PMID:22172266 RGD:7241094 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 treatment
disease_progression
IDA
ISO
mRNA:increased expression:liver: RGD PMID:22172266, PMID:23977376, PMID:23977376 RGD:7241094, RGD:14697731, RGD:14697731 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor treatment IEP
IDA
protein:increased expression:plasma
associated with liver cirrhosis
protein:increased expression:plasma (rat)
RGD PMID:17324147, PMID:15242491, PMID:18078960, PMID:8283134, PMID:12813371, PMID:21396682, PMID:20519137 RGD:4891465, RGD:38501090, RGD:15023464, RGD:14995443, RGD:14995427, RGD:5147765, RGD:5147779 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IEP mRNA:increased expression:brain: RGD PMID:20061033 RGD:7240511 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vwf von Willebrand factor IEP protein:increased expression:endothelial cell: RGD PMID:2650559 RGD:11079230 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
Fetal Inflammatory Response Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 ISO associated with Premature Birth; RGD PMID:24832219 RGD:12801490 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
malaria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr1 atypical chemokine receptor 1 susceptibility ISO ClinVar Annotator: match by term: Plasmodium vivax, resistance to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:7663520, PMID:8547665, PMID:8651934, PMID:10570183, PMID:10791881, PMID:17304246, PMID:18179887, PMID:18621010, PMID:19180233, PMID:19620399, PMID:20932074 NCBI chr13:91,827,310...91,828,875 JBrowse link
G Aicda activation-induced cytidine deaminase ISO protein:increased expression: B cell RGD PMID:27980783 RGD:30310233 NCBI chr 4:155,359,909...155,371,104
Ensembl chr 4:155,359,921...155,369,671
JBrowse link
G Ank1 ankyrin 1 ISS OMIM:609148 | OMIM:611162 MouseDO NCBI chr16:73,681,422...73,912,605
Ensembl chr16:73,681,422...73,827,488
JBrowse link
G Apoe apolipoprotein E ISO DNA:missense mutations:cds:p.C112R, p.C158R (human) RGD PMID:24116184 RGD:11039486 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Aqp4 aquaporin 4 ISS OMIM:609148 | OMIM:611162 MouseDO NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Cd36 CD36 molecule susceptibility ISO ClinVar Annotator: match by synonym: Malaria, cerebral, susceptibility to
ClinVar Annotator: match by term: Malaria, cerebral, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Susceptibility to malaria
ClinVar
CTD
OMIM
PMID:10890433, PMID:18305138, PMID:19403559, PMID:25741868 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd40 CD40 molecule severity ISO RGD PMID:11485931 RGD:11352239 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand severity ISO RGD PMID:11485931 RGD:11352239 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cish cytokine inducible SH2-containing protein susceptibility ISO ClinVar Annotator: match by OMIM:611162
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:20484391 NCBI chr 8:116,054,547...116,059,494
Ensembl chr 8:116,054,465...116,060,723
JBrowse link
G Crp C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:8730300 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 treatment
disease_progression
ISO RGD PMID:28892065, PMID:28892065 RGD:38455986, RGD:38455986 NCBI chr 9:67,699,397...67,706,068
Ensembl chr 9:67,699,379...67,706,065
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa susceptibility ISO DNA:missense mutation:cds:p.H131R (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malaria, severe, susceptibility to
CTD
OMIM
ClinVar
PMID:8636449, PMID:9843982, PMID:10675363, PMID:15367919, PMID:18347005, PMID:19915573, PMID:19965803, PMID:21109570, PMID:22992668, PMID:24033266, PMID:19965803 RGD:5147921 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb susceptibility ISO ClinVar Annotator: match by synonym: Malaria, resistance to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:12115230, PMID:15459183, PMID:16115811, PMID:16170323, PMID:17435165, PMID:20385827 NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815
JBrowse link
G Foxp3 forkhead box P3 disease_progression ISO RGD PMID:19338000, PMID:16169501 RGD:38455985, RGD:38455992 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase susceptibility
severity
ISO DNA:SNPs: :multiple
ClinVar Annotator: match by term: Susceptibility to malaria
CTD Direct Evidence: marker/mechanism
DNA:point mutation:cds:c.968T>C (human)
ClinVar
CTD
OMIM
PMID:5448, PMID:1303173, PMID:1551674, PMID:1562739, PMID:1631957, PMID:1805484, PMID:1924316, PMID:1972698, PMID:1978554, PMID:1978555, PMID:2321910, PMID:2503817, PMID:2572288, PMID:2633878, PMID:2836867, PMID:2849540, PMID:2912069, PMID:3338798, PMID:3393536, PMID:3446582, PMID:4359638, PMID:4388132, PMID:4435794, PMID:4837298, PMID:4974311, PMID:5305539, PMID:5369703, PMID:5770172, PMID:6015571, PMID:6698555, PMID:7203486, PMID:7283560, PMID:7327562, PMID:7390473, PMID:7806085, PMID:7947239, PMID:7947250, PMID:7949118, PMID:8118045, PMID:8611726, PMID:8807321, PMID:8860013, PMID:8956035, PMID:9342374, PMID:9427729, PMID:9589612, PMID:9858856, PMID:10734064, PMID:11445808, PMID:11499668, PMID:11793482, PMID:12028056, PMID:12367584, PMID:12497642, PMID:12737938, PMID:12768444, PMID:14278484, PMID:15223006, PMID:15315792, PMID:15349799, PMID:15502081, PMID:15735168, PMID:15906717, PMID:16119988, PMID:16136268, PMID:16155737, PMID:16356170, PMID:16528451, PMID:16777444, PMID:16927025, PMID:17726510, PMID:17959407, PMID:18046504, PMID:18177777, PMID:18329300, PMID:19589177, PMID:19594365, PMID:20007901, PMID:20236109, PMID:20602793, PMID:21446359, PMID:21677401, PMID:21989994, PMID:22018328, PMID:22165289, PMID:22293322, PMID:22906047, PMID:23479361, PMID:23926329, PMID:23965028, PMID:24033266, PMID:24460025, PMID:24586352, PMID:25326637, PMID:25548459, PMID:25741868, PMID:25775246, PMID:26060661, PMID:26226515, PMID:26633385, PMID:27053284, PMID:27213370, PMID:27287612, PMID:27880809, PMID:28492532, PMID:30315739, PMID:25015414, PMID:24615128 RGD:10449111, RGD:10449115 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gypc glycophorin C (Gerbich blood group) susceptibility ISO ClinVar Annotator: match by term: Malaria, resistance to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:1991173, PMID:5011657, PMID:8157284, PMID:11719395, PMID:12469115, PMID:21061946 NCBI chr18:25,312,386...25,344,614
Ensembl chr18:25,312,387...25,344,614
JBrowse link
G Hbb hemoglobin subunit beta resistance
susceptibility
ISO ClinVar Annotator: match by term: Susceptibility to malaria
ClinVar Annotator: match by term: Malaria, resistance to
ClinVar Annotator: match by term: Malaria, cerebral, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:49057, PMID:81926, PMID:88735, PMID:700140, PMID:893136, PMID:909565, PMID:1301203, PMID:1376298, PMID:1390250, PMID:1427786, PMID:1463768, PMID:1483699, PMID:1634236, PMID:1634368, PMID:1680789, PMID:1734721, PMID:1769663, PMID:1802884, PMID:1917531, PMID:1960615, PMID:1967205, PMID:1986365, PMID:2004023, PMID:2200760, PMID:2239966, PMID:2296310, PMID:2298457, PMID:2412200, PMID:2446680, PMID:2577233, PMID:2579336, PMID:2582106, PMID:2713503, PMID:2867271, PMID:2888754, PMID:2891298, PMID:2893541, PMID:2898142, PMID:2898460, PMID:2898955, PMID:2903765, PMID:3031297, PMID:3048433, PMID:3354556, PMID:3422218, PMID:3462712, PMID:3690667, PMID:3752087, PMID:3821796, PMID:4232783, PMID:4351905, PMID:5658717, PMID:5863839, PMID:6162860, PMID:6166632, PMID:6188062, PMID:6189507, PMID:6190800, PMID:6198908, PMID:6264391, PMID:6264477, PMID:6268660, PMID:6270663, PMID:6272289, PMID:6275383, PMID:6280057, PMID:6285354, PMID:6304979, PMID:6457059, PMID:6583683, PMID:6583702, PMID:6584911, PMID:6585831, PMID:6714226, PMID:6859036, PMID:6896219, PMID:7137165, PMID:7151176, PMID:7177196, PMID:7229029, PMID:7312624, PMID:7395858, PMID:7522523, PMID:7558878, PMID:7668219, PMID:7993409, PMID:8095930, PMID:8199597, PMID:8201467, PMID:8330981, PMID:8373896, PMID:8462981, PMID:8602996, PMID:8619407, PMID:8839873, PMID:8917506, PMID:9048934, PMID:9101288, PMID:9140720, PMID:9401495, PMID:9490703, PMID:9556665, PMID:9653159, PMID:9859938, PMID:10335989, PMID:10602954, PMID:10612821, PMID:11001883, PMID:11425418, PMID:11545326, PMID:11559932, PMID:11713529, PMID:11741197, PMID:11830454, PMID:11857746, PMID:11880644, PMID:11939510, PMID:12124399, PMID:12144057, PMID:12149194, PMID:12764548, PMID:12850492, PMID:13066514, PMID:13108995, PMID:13115700, PMID:13369537, PMID:13464827, PMID:13618691, PMID:13685866, PMID:13716853, PMID:13852872, PMID:14405428, PMID:14492555, PMID:14576320, PMID:14613965, PMID:14734204, PMID:14808148, PMID:15000665, PMID:15108284, PMID:15114532, PMID:15470211, PMID:15481886, PMID:15654898, PMID:15973412, PMID:16001361, PMID:16114182, PMID:16175509, PMID:16291734, PMID:16311287, PMID:16470532, PMID:16750922, PMID:17278112, PMID:17287491, PMID:17331080, PMID:17365006, PMID:17774955, PMID:18024613, PMID:18048408, PMID:18192399, PMID:18294253, PMID:18568278, PMID:18603555, PMID:19000664, PMID:19061217, PMID:19254853, PMID:19440680, PMID:19758965, PMID:19841268, PMID:19958185, PMID:20132300, PMID:20301551, PMID:20301599, PMID:20305663, PMID:20395516, PMID:20412082, PMID:20437613, PMID:20492708, PMID:20642331, PMID:20704537, PMID:20861612, PMID:20954261, PMID:21119755, PMID:21131035, PMID:21228398, PMID:21389146, PMID:21417574, PMID:21529713, PMID:21732929, PMID:21797703, PMID:22010933, PMID:22028795, PMID:22075726, PMID:22260787, PMID:22271886, PMID:22335963, PMID:22392582, PMID:22625666, PMID:22975760, PMID:23162295, PMID:23234478, PMID:23297836, PMID:23321370, PMID:23348723, PMID:23425204, PMID:23590658, PMID:23637309, PMID:23647352, PMID:23729725, PMID:24033266, PMID:24368026, PMID:24493127, PMID:24581976, PMID:24857915, PMID:25023084, PMID:25023085, PMID:25087612, PMID:25089872, PMID:25155404, PMID:25332589, PMID:25370867, PMID:25525159, PMID:25572186, PMID:25741868, PMID:25849334, PMID:25856402, PMID:26029792, PMID:26097845, PMID:26193974, PMID:26275168, PMID:26372199, PMID:26467025, PMID:26554862, PMID:27117572, PMID:27263053, PMID:27427187, PMID:27690257, PMID:27821015, PMID:28356267, PMID:28366028, PMID:28391758, PMID:28492532, PMID:28635337, PMID:28670940, PMID:29695942, PMID:30311386, PMID:31714438, PMID:32581362, PMID:11001883 RGD:1600894 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hmox1 heme oxygenase 1 ISS OMIM:609148 | OMIM:611162 MouseDO NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hp haptoglobin ISO CTD Direct Evidence: marker/mechanism CTD PMID:8730300, PMID:16597321 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Icam1 intercellular adhesion molecule 1 susceptibility ISO ClinVar Annotator: match by synonym: Malaria, cerebral, susceptibility to
ClinVar Annotator: match by term: Susceptibility to malaria
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:9259284, PMID:9861406, PMID:10417733, PMID:10699175, PMID:23609612, PMID:25741868 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma ISS OMIM:609148 | OMIM:611162 MouseDO NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ltbr lymphotoxin beta receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15788153 NCBI chr 4:157,822,838...157,829,291
Ensembl chr 4:157,822,840...157,829,241
JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 ISO ClinVar Annotator: match by synonym: Susceptibility to malaria ClinVar PMID:20484391 NCBI chr 8:116,012,126...116,046,012
Ensembl chr 8:116,012,121...116,045,954
JBrowse link
G Mir122 microRNA 122 treatment ISO RGD PMID:28123381 RGD:35673288 NCBI chr18:60,755,285...60,755,369 JBrowse link
G Mir142 microRNA 142 treatment ISO RGD PMID:28123381 RGD:35673288 NCBI chr10:75,050,839...75,050,925
Ensembl chr10:75,050,832...75,050,942
JBrowse link
G Mirlet7a1 microRNA let-7a-1 treatment ISO RGD PMID:28123381 RGD:35673288 NCBI chr17:16,417,853...16,417,946
Ensembl chr17:16,417,855...16,417,954
JBrowse link
G Mirlet7c1 microRNA let-7c-1 treatment ISO RGD PMID:28123381 RGD:35673288 NCBI chr11:16,052,873...16,052,966
Ensembl chr11:16,052,868...16,052,975
JBrowse link
G Mki67 marker of proliferation Ki-67 ISO associated with Lung Neoplasms RGD PMID:21931708 RGD:6483517 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Ncr3 natural cytotoxicity triggering receptor 3 susceptibility ISO ClinVar Annotator: match by OMIM:609148
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:17208487 NCBI chr20:5,170,169...5,175,773
Ensembl chr20:5,170,215...5,175,773
JBrowse link
G Nos2 nitric oxide synthase 2 susceptibility ISO ClinVar Annotator: match by term: Malaria, severe, resistance to
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malaria, resistance to
ClinVar
CTD
OMIM
PMID:9457101, PMID:12433515 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Pklr pyruvate kinase L/R susceptibility ISO
ISS
DNA:mutations, haplotype:multiple (human)
OMIM:609148 | OMIM:611162
DNA:missense mutation:cds:p.I90N (mouse)
MouseDO PMID:20377593, PMID:14595440 RGD:11535999, RGD:11537407 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Prf1 perforin 1 ISO RGD PMID:21525386 RGD:6482803 NCBI chr20:30,915,294...30,920,804
Ensembl chr20:30,915,213...30,921,382
JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) susceptibility ISO ClinVar Annotator: match by term: Susceptibility to malaria
ClinVar Annotator: match by term: Malaria, cerebral, resistance to
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:1378323, PMID:1737855, PMID:2146504, PMID:7689982, PMID:7919393, PMID:7949112, PMID:8434259, PMID:9312167, PMID:10403343, PMID:14618420, PMID:19229254, PMID:25741868 NCBI chr10:90,296,144...90,312,401
Ensembl chr10:90,296,141...90,312,386
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:16552072 RGD:1581333 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tbx21 T-box transcription factor 21 ISO RGD PMID:19338000 RGD:38455985 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331
JBrowse link
G Tirap TIR domain containing adaptor protein susceptibility ISO ClinVar Annotator: match by synonym: Malaria, resistance to
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
PMID:16991088, PMID:17322885, PMID:18305471 NCBI chr 8:36,382,029...36,399,625
Ensembl chr 8:36,385,353...36,388,224
JBrowse link
G Tnf tumor necrosis factor susceptibility ISO DNA:polymorphism:promoter:-376G>A
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by synonym: Malaria, cerebral, susceptibility to
CTD
OMIM
ClinVar
PMID:8056188, PMID:9818939, PMID:10369255, PMID:10450718, PMID:11261930, PMID:11506397, PMID:11826025, PMID:11896460, PMID:12485196, PMID:12746914, PMID:14681301, PMID:14718719, PMID:16418737, PMID:16865291, PMID:10369255 RGD:1624967 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tslp thymic stromal lymphopoietin ISO mRNA:altered expression:multiple (mouse) RGD PMID:28955823 RGD:38596344 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
Malarial Anemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr3a Fc fragment of IgG receptor IIIa severity
susceptibility
ISO DNA:polymorphism: :p.F176V (human) RGD PMID:20231419, PMID:23045477 RGD:11040771, RGD:11344971 NCBI chr13:89,385,775...89,396,047
Ensembl chr13:89,385,859...89,396,051
JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) severity ISO DNA:snp:promoter:g.-5699T>C (human) RGD PMID:16960783 RGD:10450507 NCBI chr10:90,296,144...90,312,401
Ensembl chr10:90,296,141...90,312,386
JBrowse link
G Tlr9 toll-like receptor 9 susceptibility ISO DNA:SNP:promoter:g.-1237T>C (rs5743836) (human) RGD PMID:23045477 RGD:11344971 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
JBrowse link
Neonatal Sepsis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g2a phospholipase A2 group IIA susceptibility ISO DNA:SNP:enhancer: (rs1891320) (human) RGD PMID:20463618 RGD:6482720 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
JBrowse link
Plasmodium falciparum malaria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 ISO protein:decreased activity:plasma (human) RGD PMID:20062916 RGD:10449041 NCBI chr 3:5,519,921...5,558,390
Ensembl chr 3:5,519,990...5,558,166
JBrowse link
G Bsg basigin (Ok blood group) ISO CTD Direct Evidence: therapeutic CTD PMID:22080952, PMID:26195724 NCBI chr 7:12,875,536...12,882,753
Ensembl chr 7:12,875,537...12,882,753
JBrowse link
G Cast calpastatin ISO protein:alter localization:erythrocyte RGD PMID:17359359 RGD:5509812 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 ISO mRNA, protein:increased expression:blood, RGD PMID:15972509 RGD:5683898 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Clec11a C-type lectin domain containing 11A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19884328 NCBI chr 1:100,290,374...100,293,515
Ensembl chr 1:100,289,295...100,293,558
JBrowse link
G Fas Fas cell surface death receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625619 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa severity ISO DNA:missense mutation:cds:p.R131H (rs1801274) (human) RGD PMID:18194515 RGD:5147927 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase severity ISO DNA:missense mutation:cds:202G>A (p.V68M) (human) RGD PMID:24943486 RGD:10449113 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gstp1 glutathione S-transferase pi 1 severity ISO RGD PMID:19635899 RGD:10450848 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hbb hemoglobin subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20305663 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hp haptoglobin severity ISO DNA:missense mutation:cds:p.K54E (human) RGD PMID:24478401 RGD:11041793 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Il13 interleukin 13 ISO protein:increased expression:plasma RGD PMID:21985368 RGD:5684362 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:haplotype:exon: RGD PMID:18396436 RGD:11530064 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO DNA:polymorphism:cds:HLA-DQB1*0501 (human) RGD PMID:11076705 RGD:11041780 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711
JBrowse link
G Tnf tumor necrosis factor severity ISO protein:increased expression:plasma RGD PMID:1984482 RGD:10450571 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
Plasmodium vivax malaria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr1 atypical chemokine receptor 1 ISO OMIM NCBI chr13:91,827,310...91,828,875 JBrowse link
Pregnancy-associated Malaria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 ISO RGD PMID:24717969 RGD:11041890 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
Sepsis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin IEP mRNA:increased expression:liver RGD PMID:9843780, PMID:15167684 RGD:1598509, RGD:10046033 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing IEP
ISO
mRNA, protein:decreasedexpression:serum, omental fat pad: RGD PMID:16488436, PMID:19481767, PMID:21962804 RGD:1599144, RGD:5686835, RGD:5686408 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adm adrenomedullin treatment IEP
ISO
protein:increased expression:plasma:
CTD Direct Evidence: marker/mechanism
associated with Jaundice,Obstructive;
CTD PMID:14766677, PMID:20132852, PMID:19009024, PMID:20132852 RGD:7364952, RGD:7364986, RGD:7364952 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27757725 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Adora2b adenosine A2B receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27757725 NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365
JBrowse link
G Adra2a adrenoceptor alpha 2A disease_progression IMP RGD PMID:19894027 RGD:6480483 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Adrb2 adrenoceptor beta 2 IDA
IEP
mRNA,protein:decreased expression:liver: RGD PMID:16603198, PMID:10409266 RGD:1598745, RGD:8548498 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Adrb3 adrenoceptor beta 3 ISO mRNA, protein:increased expression:heart left ventricle (human) RGD PMID:17999941 RGD:2292119 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
JBrowse link
G Ager advanced glycosylation end product-specific receptor treatment IMP RGD PMID:19623040 RGD:10402067 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 IEP mRNA:increased expression:duodenum, jejunum, ileum (rat) RGD PMID:12627002 RGD:4144178 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Alb albumin disease_progression ISO protein:decreased expression:serum: RGD PMID:22801198 RGD:11036079 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member treatment IEP associated with heat shock treatment;protein:altered expression, altered phosphorylation:liver, mitochondria (rat) RGD PMID:17607160 RGD:15036802 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Angpt1 angiopoietin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16005988 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Apoa1 apolipoprotein A1 treatment IDA RGD PMID:19561306 RGD:7241869 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Arg2 arginase 2 IEP protein:decreased expression:lung RGD PMID:9635249 RGD:1626297 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 IEP RGD PMID:28446393 RGD:13782063 NCBI chr 1:197,855,912...197,875,038 JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase IEP RGD PMID:7575455 RGD:69770 NCBI chr 5:64,768,397...64,777,368
Ensembl chr 5:64,768,401...64,777,368
JBrowse link
G Bad BCL2-associated agonist of cell death treatment IEP
IDA
protein:increased localization:mitochondrion RGD PMID:24011917, PMID:22683079 RGD:10053647, RGD:10053707 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G C3 complement C3 IEP
ISO
protein:increased expression:liver
mRNA:increased expression:kidney
RGD PMID:3339873, PMID:24154627 RGD:7411622, RGD:11040886 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C5 complement C5 IEP
IDA
protein:increased activation:plasma RGD PMID:18648551, PMID:14688199 RGD:5130170, RGD:1600599 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G C5ar1 complement C5a receptor 1 disease_progression IEP
IMP
RGD PMID:12897064, PMID:18648551 RGD:5130176, RGD:5130170 NCBI chr 1:78,186,777...78,195,132
Ensembl chr 1:78,186,776...78,195,328
JBrowse link
G C6 complement C6 severity IAGP RGD PMID:15638131 RGD:1600672 NCBI chr 2:54,460,333...54,533,801
Ensembl chr 2:54,466,280...54,533,797
JBrowse link
G Camp cathelicidin antimicrobial peptide IMP RGD PMID:17142779 RGD:2316243 NCBI chr 8:117,930,557...117,932,371
Ensembl chr 8:117,930,546...117,932,518
JBrowse link
G Casp3 caspase 3 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:16003065, PMID:29180187 RGD:13782295 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 IDA protein:increased activity:thymus, T cell RGD PMID:11086028 RGD:2301332 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp8 caspase 8 treatment IEP RGD PMID:18570579, PMID:29180187 RGD:2311435, RGD:13782295 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 treatment IEP RGD PMID:29180187 RGD:13782295 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cast calpastatin IEP RGD PMID:15563579 RGD:5683871 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cat catalase severity IEP RGD PMID:15836852 RGD:9068893 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 IEP RGD PMID:21652218 RGD:7248417 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP mRNA:increased expression:ileum RGD PMID:19111613 RGD:2307002 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 severity ISO RGD PMID:21208283 RGD:5683911 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP protein:increased secretion:plasma (rat) RGD PMID:18290317 RGD:4890036 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Cd28 Cd28 molecule severity ISO Higher soluble CD28 in human patients that died RGD PMID:17989345 RGD:5131622 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Cd36 CD36 molecule ISO RGD PMID:22327076 RGD:6893490 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd40 CD40 molecule ISO protein:decreased nitrosylation:monocyte RGD PMID:20473113 RGD:5490974 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand IEP mRNA:increased expression:heart (rat) RGD PMID:20933523 RGD:11352671 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A IEP RGD PMID:10451498 RGD:10043817 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta IEP protein:increased expression:skeletal muscle RGD PMID:11792653 RGD:625506 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta IEP protein:increased expression:skeletal muscle RGD PMID:11792653 RGD:625506 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Cfb complement factor B treatment ISO RGD PMID:24154627 RGD:11040886 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066
JBrowse link
G Cfh complement factor H treatment IEP
ISO
protein:decreased expression:plasma:
associated with Jaundice,Obstructive;
RGD PMID:20132852, PMID:19009024, PMID:20132852 RGD:7364952, RGD:7364986, RGD:7364952 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
JBrowse link
G Cpb2 carboxypeptidase B2 IEP protein:increased activity:plasma: RGD PMID:15497025 RGD:2313648 NCBI chr15:57,290,849...57,339,762
Ensembl chr15:57,290,849...57,339,760
JBrowse link
G Crh corticotropin releasing hormone IEP protein:increased expression:hypothalamus (rat) RGD PMID:21549066 RGD:5490558 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Crp C-reactive protein IEP
ISO
protein:increased expression:blood: RGD PMID:21797109, PMID:19060982 RGD:6482315, RGD:9491784 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csf2 colony stimulating factor 2 ISO protein:increased expression:plasma: RGD PMID:10664226 RGD:10449523 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO CTD Direct Evidence: therapeutic CTD PMID:17505274, PMID:8706460 RGD:11039434 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO protein:increased expression:lung, macrophage RGD PMID:19733456 RGD:4144897 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO RGD PMID:9284162 RGD:5135255 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 ISO protein:increased expression:multiple tissues RGD PMID:9284162 RGD:5135255 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17138957 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IEP mRNA, protein:decreased expression:liver RGD PMID:15665729 RGD:5147745 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 IEP RGD PMID:18360687, PMID:15665729 RGD:2303376, RGD:5147745 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 IEP RGD PMID:15665729 RGD:5147745 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 IEP RGD PMID:15665729 RGD:5147745 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 IEP RGD PMID:15190971 RGD:1625384 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Defb2 defensin beta 2 treatment IMP RGD PMID:17177330 RGD:9685178 NCBI chr16:75,227,468...75,241,303
Ensembl chr16:75,227,468...75,241,303
JBrowse link
G Edn1 endothelin 1 IEP mRNA, protein:increased expression:multiple (rat) RGD PMID:10838194 RGD:8662298 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon IDA protein:increased serine phosphorylation:gastrocnemius RGD PMID:12376332 RGD:11041880 NCBI chr11:84,080,273...84,090,259
Ensembl chr11:84,080,273...84,090,259
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha IEP RGD PMID:8141277 RGD:10395355 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E IDA RGD PMID:17709445 RGD:10401144 NCBI chr 2:243,819,616...243,853,987
Ensembl chr 2:243,820,661...243,852,631
JBrowse link
G Elane elastase, neutrophil expressed ISO associated with Klebsiella Infections; RGD PMID:9585238 RGD:10450543 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IEP protein:increased activity:lymphocyte: RGD PMID:22645477 RGD:9685487 NCBI chr 1:259,692,020...259,818,922
Ensembl chr 1:259,739,955...259,819,494
JBrowse link
G Ep300 E1A binding protein p300 IEP mRNA, protein:increased expression:muscle part of extensor digitorum longus (rat) RGD PMID:20538901 RGD:7364733 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Esr2 estrogen receptor 2 IDA RGD PMID:16755255 RGD:5508850 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G F11 coagulation factor XI IEP RGD PMID:12000738 RGD:1598921 NCBI chr16:50,179,458...50,201,644
Ensembl chr16:50,179,458...50,201,698
JBrowse link
G F2 coagulation factor II treatment IDA
ISO
RGD PMID:19705256, PMID:12361199 RGD:7387324, RGD:10449428 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F3 coagulation factor III, tissue factor treatment ISO
IEP
RGD PMID:9875912, PMID:26311287 RGD:11340217, RGD:11341736 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G F5 coagulation factor V severity
treatment
ISO
IMP
RGD PMID:16235188, PMID:12000738 RGD:4892622, RGD:1598921 NCBI chr13:82,479,997...82,535,540
Ensembl chr13:82,479,998...82,535,534
JBrowse link
G F7 coagulation factor VII treatment IEP
IDA
protein:decreased activity:plasma (rat) RGD PMID:3660344, PMID:12000738 RGD:2312320, RGD:1598921 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G F9 coagulation factor IX treatment IEP RGD PMID:12000738 RGD:1598921 NCBI chr  X:143,097,507...143,141,791
Ensembl chr  X:143,097,525...143,141,794
JBrowse link
G Fas Fas cell surface death receptor IEP mRNA:increased expression:liver RGD PMID:17899301 RGD:2290175 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand IEP mRNA:increased expression:liver RGD PMID:17899301 RGD:2290175 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fga fibrinogen alpha chain IEP protein:decreased expression:serum (rat) RGD PMID:24667622 RGD:9685020 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 disease_progression ISO Pneumonia associated sepsis RGD PMID:21219633 RGD:4891938 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Foxp3 forkhead box P3 severity ISO RGD PMID:25403265 RGD:38455982 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase IEP protein:decreased phosphorylation, decreased activity:T cell (rat) RGD PMID:9551931 RGD:2324866 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Gas6 growth arrest specific 6 ISO RGD PMID:16374177 RGD:1579935 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Gata3 GATA binding protein 3 severity ISO RGD PMID:25403265 RGD:38455982 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Gfer growth factor, augmenter of liver regeneration IEP protein:increased expression:serum: RGD PMID:23073658 RGD:9685733 NCBI chr10:14,059,347...14,061,703
Ensembl chr10:14,059,347...14,061,703
JBrowse link
G Ghr growth hormone receptor IEP RGD PMID:11126270 RGD:2307382 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide IEP mRNA,protein:decreased expression:aorta,heart, intestine, plasma: RGD PMID:15155262 RGD:12905047 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Ghsr growth hormone secretagogue receptor disease_progression IEP RGD PMID:15155262 RGD:12905047 NCBI chr 2:113,065,953...113,071,265
Ensembl chr 2:113,066,885...113,070,261
JBrowse link
G Gja5 gap junction protein, alpha 5 IEP mRNA, protein:increased expression:aorta endothelium RGD PMID:15942348 RGD:7207815 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Gpt glutamic--pyruvic transaminase treatment IEP RGD PMID:26814114 RGD:14975161 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A IEP protein:increased expression:lung (rat) RGD PMID:19837828 RGD:2325949 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO protein: increased expression: neutrophils RGD PMID:16849637 RGD:5688378 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO protein: increased expression: neutrophils RGD PMID:16849637 RGD:5688378 NCBI chr 1:282,265,371...282,467,842
Ensembl chr 1:282,265,370...282,462,605
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IEP protein:decreased phosphorylation,increased activity: : RGD PMID:20926980 RGD:10045370 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 disease_progression ISO RGD PMID:23131280 RGD:7245480 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hdac4 histone deacetylase 4 IEP RGD PMID:23925573 RGD:9681446 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
G Hdac6 histone deacetylase 6 IEP RGD PMID:20538901 RGD:7364733 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Hmgb1 high mobility group box 1 treatment IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:19265175, PMID:23146691, PMID:19623040, PMID:20936717 RGD:10402067, RGD:10402173 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase ISO protein: decreased expression RGD PMID:9603077 RGD:5688768 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IEP associated with burns;protein:decreased expression:skeletal muscle RGD PMID:16483253, PMID:23143056 RGD:1624233, RGD:10402864 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Htra2 HtrA serine peptidase 2 treatment IMP RGD PMID:23557966 RGD:10402934 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP mRNA:increased expression:brain (rat) RGD PMID:20451670 RGD:4145409 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:9806674, PMID:27598601, PMID:28711488 RGD:14975121, RGD:14974250 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il10 interleukin 10 treatment IEP
ISO
IDA
protein:increased expression:serum
CTD Direct Evidence: therapeutic
CTD PMID:11441115, PMID:19371254, PMID:27488951, PMID:28108420, PMID:24055021 RGD:2311053, RGD:14975262, RGD:14975261, RGD:7364867 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12b interleukin 12B IDA protein:increased expression:peritoneal fluid, plasma RGD PMID:15776385 RGD:4888507 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il13 interleukin 13 ISO
IEP
protein:decreased expression:ileum RGD PMID:10679115, PMID:21159497 RGD:4145654, RGD:8549643 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il16 interleukin 16 ISO associated with Shock, Hemorrhagic;protein:increased expression:lung RGD PMID:19641139 RGD:5024925 NCBI chr 1:145,781,923...145,881,538
Ensembl chr 1:145,781,928...145,870,912
JBrowse link
G Il17a interleukin 17A IMP RGD PMID:15776385 RGD:4888507 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il1b interleukin 1 beta treatment IEP protein:increased expression:plasma RGD PMID:17529909, PMID:21429520 RGD:1626657, RGD:7175319 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility
disease_progression
severity
ISO
IEP
mRNA, protein:increased expression:lung
associated with Premature Birth;DNA:polymorphism::
DNA:repeats: :
mRNA:increased expression:pituitary gland (rat)
protein:increased expression:serum (human)
RGD PMID:20454520, PMID:22882323, PMID:11876758, PMID:10048466, PMID:8196140, PMID:17014550 RGD:4142852, RGD:12910846, RGD:11528543, RGD:7175061, RGD:6909139, RGD:6907358 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il22 interleukin 22 IEP protein:increased expression:plasma RGD PMID:19664145 RGD:5147412 NCBI chr 7:61,236,037...61,240,502
Ensembl chr 7:61,236,037...61,240,502
JBrowse link
G Il4 interleukin 4 ISO protein:increased expression:plasma RGD PMID:25403265 RGD:38455982 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 treatment IAGP
IEP
IDA
associated with Diabetes Mellitus, Non-Insulin-Dependent; mRNA, protein:increased expression:liver, extracellular space (rat) RGD PMID:19079684, PMID:27598601, PMID:25317848 RGD:2307280, RGD:14975121, RGD:11062009 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 IEP RGD PMID:23073793 RGD:7495805 NCBI chr 7:135,803,723...135,831,006
Ensembl chr 7:135,803,698...135,832,652
JBrowse link
G Irs1 insulin receptor substrate 1 IDA protein:decreased tyrosine phosphorylation, increased serine phosphorylation:gastrocnemius RGD PMID:19781177 RGD:6482862 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Itga4 integrin subunit alpha 4 ISO protein:increased expression:neutrophil RGD PMID:19011162 RGD:13593535 NCBI chr 3:66,178,745...66,265,547
Ensembl chr 3:66,193,059...66,263,960
JBrowse link
G Jak2 Janus kinase 2 treatment IDA RGD PMID:24228589 RGD:10411888 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 ISO RGD PMID:21799073 RGD:6892955 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Klkb1 kallikrein B1 IMP RGD PMID:22352684 RGD:7297048 NCBI chr16:50,151,127...50,175,407
Ensembl chr16:50,152,008...50,175,458
JBrowse link
G Lbp lipopolysaccharide binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22167001 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Lep leptin IEP RGD PMID:18575315 RGD:5128818 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lipc lipase C, hepatic type IDA protein:decreased expression:diaphragm, heart, adipose tissue (rat) RGD PMID:2113037 RGD:2308797 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248
JBrowse link
G Lta lymphotoxin alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:22977509 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677
JBrowse link
G Ltf lactotransferrin ISO RGD PMID:23425819 RGD:7243861 NCBI chr 8:119,290,416...119,313,261
Ensembl chr 8:119,290,416...119,313,261
JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15489642 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15489642 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO associated with Premature Birth;DNA:polymorphism:exon: RGD PMID:22882323 RGD:12910846 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Mfn2 mitofusin 2 IEP mRNA:decreased expression:liver (rat) RGD PMID:24720571 RGD:13204837 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mif macrophage migration inhibitory factor ISO CTD Direct Evidence: therapeutic CTD PMID:9892616, PMID:17585860 RGD:4891012 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mir155 microRNA 155 ISO RGD PMID:27434558, PMID:29979224 RGD:21079467, RGD:21081538 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir223 microRNA 223 ISO RNA:increased expression:plasma: RGD PMID:24680405 RGD:21408586 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Mmp1 matrix metallopeptidase 1 IEP RGD PMID:23478082 RGD:8549749 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment IMP RGD PMID:23479197 RGD:8657110 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:16003065, PMID:23479197 RGD:8657110 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase ISO RGD PMID:18424617 RGD:5130966 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b IEP protein:decreased expression:mitochondrion, skeletal muscle RGD PMID:6128308 RGD:2298978 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt1 metallothionein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374846 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17374846 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mtor mechanistic target of rapamycin kinase IDA RGD PMID:20577146 RGD:10041013 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mylk myosin light chain kinase ISO RGD PMID:16399953 RGD:1581052 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158
JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 IDA RGD PMID:22952679 RGD:13801198 NCBI chr 1:264,298,671...264,303,712
Ensembl chr 1:264,298,669...264,303,762
JBrowse link
G Nefh neurofilament heavy severity ISO RGD PMID:30677080 RGD:27226881 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nefl neurofilament light disease_progression ISO RGD PMID:30677080 RGD:27226881 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 susceptibility ISO
IEP
DNA:missense mutations, frameshift mutation:cds:p.R702W, p.G908R, 3020_3021insC (human)
mRNA:increased expression:intestine mucosa (rat)
RGD PMID:21460759, PMID:24059417 RGD:5508752, RGD:8547531 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Nos1 nitric oxide synthase 1 IMP RGD PMID:17191663 RGD:1642148 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nos2 nitric oxide synthase 2 ISO
IEP
associated with lung injury
CTD Direct Evidence: marker/mechanism
CTD PMID:17138957, PMID:20035746, PMID:21184738, PMID:15665729 RGD:4891414, RGD:5147745 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 ISO protein:increased expression:heart
CTD Direct Evidence: marker/mechanism
CTD PMID:20035746, PMID:17999941 RGD:2292119 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment ISO
IDA
protein:decreased expression:alveolar macrophage RGD PMID:21057058, PMID:21787473 RGD:4892317, RGD:7174711 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Otc ornithine carbamoyltransferase IEP mRNA:decreased expression:liver (rat) RGD PMID:10353541 RGD:4144069 NCBI chr  X:13,524,804...13,601,074
Ensembl chr  X:13,524,607...13,601,069
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 disease_progression ISO protein:increased expression:myeloid suppressor cell (mouse) RGD PMID:22451518 RGD:6771205 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pgf placental growth factor ISO protein:increased expression:plasma RGD PMID:16702604 RGD:6483601 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO RGD PMID:20508212 RGD:6482683 NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337
JBrowse link
G Pla2g4a phospholipase A2 group IVA IDA protein:increased activity:liver RGD PMID:9879654 RGD:1642481 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Plat plasminogen activator, tissue type treatment IDA RGD PMID:12000738 RGD:1598921 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plau plasminogen activator, urokinase disease_progression ISO Pneumonia associated sepsis RGD PMID:21219633 RGD:4891938 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO protein:increased expression:plasma RGD PMID:22550400 RGD:6483789 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha severity ISO DNA:knockout::associated with more severe disease (mouse) RGD PMID:22089192 RGD:5562037 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IEP mRNA:decreased expression:skeletal muscle RGD PMID:20647557 RGD:6484531 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ppargc1b PPARG coactivator 1 beta IEP mRNA:decreased expression:skeletal muscle RGD PMID:20647557 RGD:6484531 NCBI chr18:56,626,725...56,650,524
Ensembl chr18:56,626,712...56,728,968
JBrowse link
G Prkcq protein kinase C, theta IEP protein:decreased expression:lymphocyte RGD PMID:11735277 RGD:1625613 NCBI chr17:70,971,915...71,105,286
Ensembl chr17:70,971,915...71,105,286
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment
disease_progression
ISO
IEP
CTD Direct Evidence: therapeutic
mRNA, protein:decreased expression:liver, plasma
CTD PMID:11820775, PMID:17556722, PMID:22940033, PMID:15241104 RGD:11100029, RGD:11250412 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEP protein:increased expression:nucleus, lung RGD PMID:17626913 RGD:2298853 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Retn resistin ISO protein:increased expression:serum RGD PMID:19545363 RGD:7207151 NCBI chr12:2,201,909...2,203,649
Ensembl chr12:2,201,891...2,204,249
JBrowse link
G Rpl4 ribosomal protein L4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27978524 NCBI chr 8:69,121,682...69,126,805
Ensembl chr 8:69,121,682...69,126,805
JBrowse link
G Rpl9 ribosomal protein L9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27978524 NCBI chr14:44,524,419...44,527,613
Ensembl chr14:44,524,416...44,527,613
JBrowse link
G Rxra retinoid X receptor alpha IDA
IEP
protein:altered localization:liver
protein:decreased expression:liver
RGD PMID:19008781, PMID:17483744 RGD:2317466, RGD:1643106 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G S100b S100 calcium binding protein B ISO RGD PMID:19809934 RGD:5508796 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Sell selectin L IEP
IMP
RGD PMID:16026013, PMID:15677732 RGD:5685706, RGD:5686285 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
JBrowse link
G Selp selectin P ISO protein:increased expression:multiple RGD PMID:20690979 RGD:6478679 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpine1 serpin family E member 1 treatment ISO
IDA
associated with Pneumonia; protein:increased expression:plasma RGD PMID:19753144, PMID:12000738 RGD:4144830, RGD:1598921 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Slc38a2 solute carrier family 38, member 2 IEP RGD PMID:20338592 RGD:9999218 NCBI chr 7:138,088,654...138,100,869
Ensembl chr 7:138,088,649...138,100,841
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 IEP mRNA:decreased expression:liver RGD PMID:10500057 RGD:631887 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Socs1 suppressor of cytokine signaling 1 IEP protein:increased expression:gastrocnemius
mRNA:increased expression:liver
RGD PMID:12644450, PMID:11312157 RGD:2298924, RGD:634751 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Socs2 suppressor of cytokine signaling 2 IEP protein:increased expression:gastrocnemius RGD PMID:12644450 RGD:2298924 NCBI chr 7:36,495,496...36,500,878
Ensembl chr 7:36,495,480...36,499,784
JBrowse link
G Socs3 suppressor of cytokine signaling 3 IEP protein:increased expression:gastrocnemius
mRNA:increased expression:liver
RGD PMID:12644450, PMID:11312157 RGD:2298924, RGD:634751 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Sod1 superoxide dismutase 1 IEP RGD PMID:26266917 RGD:11035300 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 IEP mRNA, protein:increased expression:lung RGD PMID:26266917 RGD:11035300 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 IEP RGD PMID:26266917 RGD:11035300 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Stat1 signal transducer and activator of transcription 1 IDA protein:increased activity:liver, lung, small intestine RGD PMID:17067487 RGD:2291905 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat3 signal transducer and activator of transcription 3 treatment IDA RGD PMID:24228589 RGD:10411888 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stat4 signal transducer and activator of transcription 4 ISO RGD PMID:11257135 RGD:7207876 NCBI chr 9:54,340,649...54,457,753
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat6 signal transducer and activator of transcription 6 severity ISO RGD PMID:11257135 RGD:7207876 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link
G Tbx21 T-box transcription factor 21 severity ISO RGD PMID:25403265 RGD:38455982 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331
JBrowse link
G Tfpi tissue factor pathway inhibitor IEP protein:decreased activity:plasma: RGD PMID:15497025 RGD:2313648 NCBI chr 3:71,852,738...71,902,127
Ensembl chr 3:71,852,744...71,893,618
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16003065 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfbi transforming growth factor, beta induced ISO CTD Direct Evidence: marker/mechanism CTD PMID:27887929 NCBI chr17:8,400,123...8,429,338
Ensembl chr17:8,400,146...8,429,338
JBrowse link
G Thbd thrombomodulin IEP RGD PMID:17577447 RGD:2312462 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Tlr2 toll-like receptor 2 IEP associated with Liver Diseases;mRNA:increased expression:liver
associated with Burns;mRNA:increased expression:liver, lung, kidney
RGD PMID:19489280, PMID:12831613, PMID:14604479 RGD:2312497, RGD:1302750, RGD:2312732 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 IEP
ISO
associated with Liver Diseases;mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism
CTD PMID:20624996, PMID:19489280, PMID:14604479 RGD:2312497, RGD:2312732 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor treatment IEP
ISO
IDA
mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism
CTD PMID:8741040, PMID:9806674, PMID:15489642, PMID:19695174, PMID:27488951, PMID:24055021, PMID:15665729 RGD:4144094, RGD:14975262, RGD:7364867, RGD:5147745 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Top2a DNA topoisomerase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27978524 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Tslp thymic stromal lymphopoietin treatment
disease_progression
ISO protein:increased expression:peritoneum, plasma (mouse) RGD PMID:24990542, PMID:26934097 RGD:38549375, RGD:38596335 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
G Xdh xanthine dehydrogenase treatment IDA RGD PMID:19751566 RGD:7247648 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
toxic shock syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin treatment IDA RGD PMID:2424486 RGD:10046036 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Adk adenosine kinase ISO RGD PMID:8207212 RGD:6482670 NCBI chr15:3,033,535...3,435,888
Ensembl chr15:3,033,495...3,435,888
JBrowse link
G Adm adrenomedullin IDA
IMP
RGD PMID:17318497, PMID:17766482 RGD:1625310, RGD:1642599 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adrb2 adrenoceptor beta 2 disease_progression
treatment
ISO DNA:polymorphism: :rs1042717(human) RGD PMID:19850944, PMID:16076286 RGD:8548487, RGD:8548529 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO RGD PMID:21270403 RGD:6767566 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Aqp1 aquaporin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24028651 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G C5ar1 complement C5a receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18063050 NCBI chr 1:78,186,777...78,195,132
Ensembl chr 1:78,186,776...78,195,328
JBrowse link
G Cckbr cholecystokinin B receptor IEP mRNA:increased expression:myocardium RGD PMID:15948246 RGD:2311332 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 disease_progression ISO RGD PMID:28834779 RGD:14995949 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:18323746 RGD:10450579 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
G Eno2 enolase 2 IEP proteiin:increased expression:serum RGD PMID:17083782 RGD:2293748 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Fancc FA complementation group C ISO RGD PMID:17404312 RGD:11045879 NCBI chr17:826,512...955,703
Ensembl chr17:833,509...955,615
JBrowse link
G Gc GC, vitamin D binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:17852808 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:18208666 RGD:4145362 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B susceptibility ISO associated wit community-acquired pneumonia;DNA:SNP: :1267A>G (human) RGD PMID:12771604 RGD:5147601 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Ifng interferon gamma ISO protein:increased expression:plasma RGD PMID:25403265 RGD:38455982 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il10 interleukin 10 onset ISO protein:increased expression:plasma RGD PMID:12117955, PMID:12117955, PMID:25403265, PMID:7593621 RGD:1598471, RGD:1598471, RGD:38455982, RGD:11049456 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il19 interleukin 19 ISO RGD PMID:18246602 RGD:5037232 NCBI chr13:47,663,592...47,677,869
Ensembl chr13:47,664,080...47,670,407
JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment
susceptibility
ISO human gene in a mouse model
associated with Precursor Cell Lymphoblastic Leukemia-Lymphoma;DNA:polymorphism::
RGD PMID:15516267, PMID:23014359 RGD:8551736, RGD:11522756 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il20ra interleukin 20 receptor subunit alpha ISO mRNA:increased expression:multiple RGD PMID:18246602 RGD:5037232 NCBI chr 1:15,180,328...15,222,785
Ensembl chr 1:15,180,328...15,222,785
JBrowse link
G Il20rb interleukin 20 receptor subunit beta ISO mRNA:increased expression:multiple RGD PMID:18246602 RGD:5037232 NCBI chr 8:108,745,906...108,778,561
Ensembl chr 8:108,747,204...108,777,717
JBrowse link
G Il6 interleukin 6 treatment ISO RGD PMID:2124237 RGD:11060276 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO associated with acute pyelonephritis;DNA:SNPs, missense mutations, haplotypes:promoter, cds:multiple RGD PMID:17202308, PMID:17202308 RGD:6903268, RGD:6903268 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Mc2r melanocortin 2 receptor IEP protein:increased expression:liver (rat) RGD PMID:2822467 RGD:6484558 NCBI chr18:64,166,959...64,178,729
Ensembl chr18:64,167,191...64,177,729
JBrowse link
G Mif macrophage migration inhibitory factor IMP
IDA
RGD PMID:17381395, PMID:17565848 RGD:4891013, RGD:1641978 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mir155 microRNA 155 ISO RGD PMID:29979224 RGD:21081538 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 susceptibility ISO associated with Burns; DNA:missense mutation:cds:m.4216T>C (human) RGD PMID:19487983 RGD:5148017 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Nos2 nitric oxide synthase 2 IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:8745224, PMID:16601845 RGD:1580268 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nppc natriuretic peptide C ISO protein:increased expression:plasma RGD PMID:8117275 RGD:1642297 NCBI chr 9:93,731,436...93,735,636
Ensembl chr 9:93,731,436...93,735,636
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase ISO RGD PMID:15677345 RGD:8657146 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO RGD PMID:12445868 RGD:10414070 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO RGD PMID:20693875 RGD:6484122 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:19320827, PMID:21850534 RGD:11100015, RGD:11100041 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091
JBrowse link
G Ptx3 pentraxin 3 ISO protein:increased expression:plasma (human) RGD PMID:30687307 RGD:38508896 NCBI chr 2:158,097,843...158,103,653
Ensembl chr 2:158,097,843...158,103,653
JBrowse link
G RT1-Da RT1 class II, locus Da disease_progression ISO associated with Burns
CTD Direct Evidence: marker/mechanism
CTD PMID:28771573, PMID:17568330, PMID:15644645 RGD:5490160, RGD:5490203 NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 ISO mRNA:decreased expression:blood RGD PMID:15644645 RGD:5490203 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G Sell selectin L IEP protein:increased expression:plasma RGD PMID:19375498 RGD:5685700 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO RGD PMID:16732381 RGD:1599323 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Serpine1 serpin family E member 1 susceptibility ISO associated with Pneumonia; DNA:polymorphism:promoter:rs1799768 (human) RGD PMID:20429897 RGD:4144828 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serpinf1 serpin family F member 1 severity ISO protein:decreased expression:plasma (human) RGD PMID:6158114 RGD:36174004 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
G Serping1 serpin family G member 1 treatment ISO RGD PMID:8172580 RGD:8661646 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078
JBrowse link
G Sftpb surfactant protein B ISO associated with Pneumonia;DNA:polymorphism: :1580C>T (human) RGD PMID:15190959 RGD:4143404 NCBI chr 4:100,166,855...100,175,941
Ensembl chr 4:100,166,863...100,175,938
JBrowse link
G Tbxa2r thromboxane A2 receptor treatment IMP RGD PMID:7816742 RGD:11059599 NCBI chr 7:11,253,153...11,259,233
Ensembl chr 7:11,253,180...11,257,977
JBrowse link
G Tfpi tissue factor pathway inhibitor treatment ISO RGD PMID:11776329 RGD:11062085 NCBI chr 3:71,852,738...71,902,127
Ensembl chr 3:71,852,744...71,893,618
JBrowse link
G Thpo thrombopoietin ISO protein:increased expression:serum: RGD PMID:20467749 RGD:10449021 NCBI chr11:82,845,676...82,853,439
Ensembl chr11:83,868,655...83,873,910
Ensembl chr11:83,868,655...83,873,910
JBrowse link
G Tnf tumor necrosis factor treatment ISO
IEP
ClinVar Annotator: match by term: Septic shock, susceptibility to
protein:increased expression:peritoneal macrophage, cell surface (rat)
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:8056188, PMID:9818939, PMID:10450718, PMID:11261930, PMID:11506397, PMID:11826025, PMID:11896460, PMID:12485196, PMID:12746914, PMID:14681301, PMID:14718719, PMID:16418737, PMID:16865291, PMID:20054000, PMID:12622907, PMID:2213560 RGD:1598936, RGD:10449465 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
Viremia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bst2 bone marrow stromal cell antigen 2 ISO associated with Retroviridae Infections; RGD PMID:28381565 RGD:14398820 NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16103
    syndrome 6989
      Systemic Inflammatory Response Syndrome 331
        Cytokine Release Syndrome 0
        Fetal Inflammatory Response Syndrome 1
        Sepsis + 329
        toxic shock syndrome 46
Path 2
Term Annotations click to browse term
  disease 16103
    Pathological Conditions, Signs and Symptoms 8723
      Pathologic Processes 6127
        Shock 351
          Systemic Inflammatory Response Syndrome 331
            Cytokine Release Syndrome 0
            Fetal Inflammatory Response Syndrome 1
            Sepsis + 329
            toxic shock syndrome 46
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.