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ONTOLOGY REPORT - ANNOTATIONS


Term:Presbycusis
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Accession:DOID:9000307 term browser browse the term
Definition:Gradual bilateral hearing loss associated with aging that is due to progressive degeneration of cochlear structures and central auditory pathways. Hearing loss usually begins with the high frequencies then progresses to sounds of middle and low frequencies.
Synonyms:exact_synonym: ARHL;   Age-related hearing loss;   Presbyacusia;   Presbycuses;   Senile deafness
 primary_id: MESH:D011304;   RDO:0006412
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Presbycusis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actg1 actin, gamma 1 JBrowse link 10 109,518,429 109,521,288 RGD:1331525
G Aqp4 aquaporin 4 JBrowse link 18 6,766,009 6,782,757 RGD:8695953
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:8655551
G Cacna1d calcium voltage-gated channel subunit alpha1 D JBrowse link 16 6,110,294 6,405,022 RGD:10045570
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:8655636
G Cdh23 cadherin-related 23 JBrowse link 20 29,857,018 30,263,758 RGD:737781
RGD:8662287
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:8661662
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:7495801
RGD:7495803
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:7794838
RGD:7495803
G Hspb1 heat shock protein family B (small) member 1 JBrowse link 12 23,839,390 23,841,051 RGD:10402574
G Il1r2 interleukin 1 receptor type 2 JBrowse link 9 46,840,646 46,881,241 RGD:8662870
G LOC100361457 actin, gamma 1 propeptide-like JBrowse link 3 75,643,053 75,644,978 RGD:1331525
G Nat2 N-acetyltransferase 2 JBrowse link 16 23,960,709 23,991,570 RGD:8552649
G Polg DNA polymerase gamma, catalytic subunit JBrowse link 1 141,172,117 141,188,893 RGD:8694161
G Sirt3 sirtuin 3 JBrowse link 1 213,613,502 213,636,061 RGD:8158103
G Slc26a5 solute carrier family 26 member 5 JBrowse link 4 9,795,811 9,860,904 RGD:9585690
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:8655636
RGD:8655665
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:8158103
G Tbc1d24 TBC1 domain family, member 24 JBrowse link 10 13,551,100 13,576,739 RGD:11537394
G Tyr tyrosinase JBrowse link 1 151,012,598 151,106,802 RGD:8694324
RGD:8694327

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 0
    Diseases of the Aged 1171
      Presbycusis 20
        Age-Related Hearing Impairment 1 0
        Presbycusis 2 0
Path 2
Term Annotations click to browse term
  disease 15620
    disease of anatomical entity 14949
      nervous system disease 10219
        sensory system disease 4681
          Otorhinolaryngologic Diseases 1075
            auditory system disease 684
              Hearing Disorders 569
                Hearing Loss 565
                  sensorineural hearing loss 459
                    Presbycusis 20
                      Age-Related Hearing Impairment 1 0
                      Presbycusis 2 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.