Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Pain
go back to main search page
Accession:DOID:9000641 term browser browse the term
Definition:An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Synonyms:exact_synonym: Ache;   Burning Pain;   Crushing Pain;   Crushing Pains;   Migratory Pain;   Migratory Pains;   Physical Suffering;   Physical Sufferings;   Radiating Pain;   Radiating Pains;   aches;   burning pains;   splitting pain;   splitting pains
 primary_id: MESH:D010146
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A ISO CTD Direct Evidence: therapeutic CTD PMID:28193520 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Ace angiotensin I converting enzyme IMP RGD PMID:18555989 RGD:2325233 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Adm adrenomedullin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17043245 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Aif1 allograft inflammatory factor 1 IEP associated with Diabetes Mellitus, Experimental; protein:increased expression:spinal cord dorsal horn (rat) RGD PMID:18186080 RGD:2313034 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17084039 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin ISO CTD Direct Evidence: therapeutic CTD PMID:4126124 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Alox5 arachidonate 5-lipoxygenase IMP RGD PMID:19580807 RGD:2317533 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Aqp1 aquaporin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20018876 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Avp arginine vasopressin ISO CTD Direct Evidence: therapeutic CTD PMID:2271928, PMID:6094376 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Bdkrb1 bradykinin receptor B1 IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:20152050, PMID:17988733 RGD:5129214 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20152050 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Bdnf brain-derived neurotrophic factor IEP RGD PMID:20452292 RGD:4891137 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17088553 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Casp1 caspase 1 IMP RGD PMID:19853379 RGD:2315887 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Cck cholecystokinin IDA RGD PMID:17157334 RGD:2313635 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Cckbr cholecystokinin B receptor IMP associated with Diabetes Mellitus, Experimental RGD PMID:16527403 RGD:2311323 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IDA RGD PMID:18419759 RGD:2307043 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 IMP RGD PMID:11438578 RGD:2306307 NCBI chr19:10,674,189...10,681,145
Ensembl chr19:10,674,189...10,681,145
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IMP RGD PMID:11438578 RGD:2306307 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 IMP
ISO
associated with Osteoarthritis, Knee; RGD PMID:18419759, PMID:23185004 RGD:2307043, RGD:8661785
G Clcn7 chloride voltage-gated channel 7 IEP mRNA:increased expression:spinal cord dorsal horn RGD PMID:11846422 RGD:1600865 NCBI chr10:14,492,844...14,518,167
Ensembl chr10:14,492,844...14,516,894
JBrowse link
G Cnr1 cannabinoid receptor 1 IMP
ISO
CTD Direct Evidence: therapeutic CTD PMID:19193902, PMID:19661434 RGD:2314649 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 IMP RGD PMID:19409856 RGD:2316193 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Comt catechol-O-methyltransferase severity IMP
ISO
associated with Multiple Sclerosis;DNA:polymorphism:cds:rs4680(p.V158M)(human)
CTD Direct Evidence: marker/mechanism
CTD PMID:20561508, PMID:17084978, PMID:24290452 RGD:2289747, RGD:13450948 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Crh corticotropin releasing hormone ISO CTD Direct Evidence: therapeutic CTD PMID:16495007 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Csf2 colony stimulating factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8622042 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7541186, PMID:8622042, PMID:10864982 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 IMP associated with Bone Neoplasms RGD PMID:20736819 RGD:4892020 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IMP RGD PMID:11438578 RGD:2306307 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Disc1 DISC1 scaffold protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:20561508 NCBI chr19:57,818,838...58,069,992
Ensembl chr19:57,820,260...58,066,152
JBrowse link
G Drd2 dopamine receptor D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15996639 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19429182, PMID:20042899 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19081190 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Gjb1 gap junction protein, beta 1 ISO ClinVar Annotator: match by term: Pain ClinVar PMID:16096811, PMID:21291455, PMID:22243284, PMID:25388846, PMID:25741868, PMID:26467025, PMID:28448691, PMID:28492532 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 ISO CTD Direct Evidence: therapeutic CTD PMID:18155693 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Hcrt hypocretin neuropeptide precursor ISO CTD Direct Evidence: therapeutic CTD PMID:16202530 NCBI chr10:88,669,216...88,670,430
Ensembl chr10:88,669,214...88,670,430
JBrowse link
G Hgf hepatocyte growth factor ISO CTD Direct Evidence: therapeutic CTD PMID:26000320 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hoxd1 homeo box D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21151121 NCBI chr 3:61,685,619...61,687,758
Ensembl chr 3:61,685,619...61,687,758
JBrowse link
G Hrh1 histamine receptor H 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12128009, PMID:14569158 NCBI chr 4:146,374,596...146,458,148
Ensembl chr 4:146,455,332...146,457,074
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO CTD Direct Evidence: therapeutic CTD PMID:12595749, PMID:21945716 RGD:5683627 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B IDA RGD PMID:16165284 RGD:1626470 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IDA RGD PMID:17451674 RGD:1624996 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Htr3b 5-hydroxytryptamine receptor 3B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17600820 NCBI chr 8:53,247,881...53,278,170
Ensembl chr 8:53,248,705...53,277,859
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17600820 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G Il18 interleukin 18 IDA RGD PMID:19853379 RGD:2315887 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO CTD Direct Evidence: therapeutic CTD PMID:15317861 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il2 interleukin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:12421473 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il6st interleukin 6 signal transducer ISO RGD PMID:20626857 RGD:5509945 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Kng2 kininogen 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:1281941, PMID:3951883, PMID:10445233, PMID:10543429, PMID:16076651, PMID:20018876, PMID:29655911 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Ngf nerve growth factor treatment IMP
ISO
associated with Cystitis, Interstitial RGD PMID:19103210, PMID:17905097 RGD:2303798, RGD:7242806 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ngfr nerve growth factor receptor IMP associated with Inflammation RGD PMID:20060234 RGD:5144063 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nos3 nitric oxide synthase 3 IMP RGD PMID:18079061 RGD:2292111 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nppa natriuretic peptide A ISO CTD Direct Evidence: therapeutic CTD PMID:13679232 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nppb natriuretic peptide B ISO CTD Direct Evidence: therapeutic CTD PMID:27687165 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Npr1 natriuretic peptide receptor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:27687165 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090
JBrowse link
G Nrg1 neuregulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20561508 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Ntsr1 neurotensin receptor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:20727387 NCBI chr 3:175,982,313...176,046,345
Ensembl chr 3:175,885,894...176,046,345
JBrowse link
G Oprd1 opioid receptor, delta 1 IDA RGD PMID:12710986 RGD:2316589 NCBI chr 5:150,288,126...150,323,063
Ensembl chr 5:150,288,126...150,323,063
JBrowse link
G Oprk1 opioid receptor, kappa 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9463367 NCBI chr 5:13,742,655...13,760,460
Ensembl chr 5:13,744,658...13,760,305
JBrowse link
G Oprm1 opioid receptor, mu 1 IDA RGD PMID:12710986 RGD:2316589 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IMP
ISO
CTD Direct Evidence: therapeutic CTD PMID:6094376, PMID:17420069, PMID:17664006 RGD:2304129 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G Pdyn prodynorphin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17670969, PMID:20068450 NCBI chr 3:122,194,327...122,206,671
Ensembl chr 3:122,194,329...122,206,671
JBrowse link
G Penk proenkephalin ISO CTD Direct Evidence: therapeutic CTD PMID:15833551 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Plcb1 phospholipase C beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16405873 NCBI chr 3:127,721,244...128,419,565
Ensembl chr 3:128,155,069...128,419,545
JBrowse link
G Pnoc prepronociceptin ISO CTD Direct Evidence: therapeutic CTD PMID:19231294 NCBI chr15:48,805,841...48,833,071
Ensembl chr15:48,805,228...48,833,285
JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:4345333, PMID:6094376, PMID:20084599 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IMP RGD PMID:18387855 RGD:2301890 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A treatment IDA RGD PMID:20359166 RGD:10002735 NCBI chr 4:29,976,485...30,247,371
Ensembl chr 4:29,978,739...30,241,911
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IEP protein:increased expression:spinal cord RGD PMID:12384231 RGD:7775057 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Prokr1 prokineticin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16793879 NCBI chr 4:119,375,790...119,386,551
Ensembl chr 4:119,375,778...119,386,590
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IEP
IMP
associated with Osteoarthritis, Knee;mRNA, protein:increased expression:spinal cord RGD PMID:18637715, PMID:17942724 RGD:2300223, RGD:2300252 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 susceptibility IMP
ISO
IEP
associated with lung neoplasm;DNA:SNP:exon:rs5275 (human)
associated with Osteoarthritis, Knee;mRNA, protein:increased expression:spinal cord
RGD PMID:18497304, PMID:19773451, PMID:18637715 RGD:2300228, RGD:5135482, RGD:2300223 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptn pleiotrophin severity ISO RGD PMID:20826137 RGD:10043829 NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996
JBrowse link
G Scn4a sodium voltage-gated channel alpha subunit 4 ISO ClinVar Annotator: match by term: Pain ClinVar PMID:25741868, PMID:30311386 NCBI chr10:94,505,026...94,557,803
Ensembl chr10:94,505,026...94,557,764
JBrowse link
G Slc6a1 solute carrier family 6 member 1 ISO RGD PMID:17918738 RGD:1643217 NCBI chr 4:146,258,842...146,292,176
Ensembl chr 4:146,276,862...146,292,213
JBrowse link
G Slc9a1 solute carrier family 9 member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19248819 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Tac1 tachykinin, precursor 1 IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:7694222, PMID:10445233, PMID:17493276 RGD:2304337 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tacr1 tachykinin receptor 1 IMP RGD PMID:18407414 RGD:2304276 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504
JBrowse link
G Tacr3 tachykinin receptor 3 IMP RGD PMID:19093101 RGD:2304256 NCBI chr 2:240,021,152...240,118,971
Ensembl chr 2:240,021,152...240,118,971
JBrowse link
G Tjp1 tight junction protein 1 IEP associated with Inflammation;protein:increased expression:brain RGD PMID:19319146 RGD:2325136 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tlr2 toll-like receptor 2 IDA RGD PMID:24204973 RGD:8553185 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 IMP RGD PMID:18662331 RGD:2312574 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18582539, PMID:20383154 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEP protein:increased expression:dorsal root ganglion (rat) RGD PMID:21248590 RGD:5130897 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Trh thyrotropin releasing hormone ISO CTD Direct Evidence: therapeutic CTD PMID:6409194 NCBI chr 4:124,110,716...124,113,242
Ensembl chr 4:124,110,716...124,113,242
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20601631 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16996476, PMID:17575321, PMID:20422007, PMID:23006841 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
G Vip vasoactive intestinal peptide ISO CTD Direct Evidence: therapeutic CTD PMID:9920454 NCBI chr 1:42,169,307...42,177,582
Ensembl chr 1:42,169,501...42,177,582
JBrowse link
Abdominal Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmbs hydroxymethylbilane synthase ISO ClinVar Annotator: match by term: Abdominal pain ClinVar PMID:30311386 NCBI chr 8:48,667,278...48,674,673
Ensembl chr 8:48,667,275...48,674,748
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IDA RGD PMID:24291101 RGD:10043376 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link
Acute Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase susceptibility ISO associated with Anemia, Sickle Cell;DNA:polymorphism:cds:p.V158M(human) RGD PMID:25102390 RGD:13450943 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
amyotrophic neuralgia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Septin9 septin 9 ISO
ISS
ClinVar Annotator: match by term: Hereditary Neuralgic Amyotrophy (HNA)
ClinVar Annotator: match by term: Hereditary neuralgic amyotrophy
OMIM:162100
ClinVar
MouseDO
PMID:16186812, PMID:17546647, PMID:18492087, PMID:19139049, PMID:19204161, PMID:19451530, PMID:20019224, PMID:22981636, PMID:25741868, PMID:26467025, PMID:28492532 NCBI chr10:106,208,308...106,340,747
Ensembl chr10:106,264,434...106,348,490
JBrowse link
Angina Pectoris term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 ISO RGD PMID:11527135 RGD:5129114 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Adrb2 adrenoceptor beta 2 ISO RGD PMID:11527135 RGD:5129114 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Avp arginine vasopressin ISO CTD Direct Evidence: marker/mechanism CTD PMID:11128043, PMID:11791009 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Cpb2 carboxypeptidase B2 ISO RGD PMID:12624641 RGD:1598479 NCBI chr15:57,290,849...57,339,762
Ensembl chr15:57,290,849...57,339,760
JBrowse link
G Mir146a microRNA 146a ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:28,962,476...28,962,570
Ensembl chr10:28,962,476...28,962,570
JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir21 microRNA 21 ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:1730212 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:16421174 RGD:1581390 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
Angina, Stable term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F7 coagulation factor VII ISO protein:increased activity:plasma (human) RGD PMID:17357481 RGD:11049525 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20981132 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20981132 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20981132 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
Arthralgia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd26 ankyrin repeat domain 26 ISO ClinVar Annotator: match by term: Joint pains ClinVar PMID:30311386 NCBI chr 4:150,548,656...150,616,928
Ensembl chr 4:150,547,467...150,616,895
JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7543699 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Eln elastin ISO ClinVar Annotator: match by term: Joint pains ClinVar PMID:30311386 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Mvk mevalonate kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10369261 NCBI chr12:47,904,266...47,920,457
Ensembl chr12:47,904,719...47,919,400
JBrowse link
G Tsc2 TSC complex subunit 2 ISO ClinVar Annotator: match by term: Joint pains ClinVar PMID:28492532, PMID:30311386 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
G Wnt10a Wnt family member 10A ISO ClinVar Annotator: match by term: JOINT PAINS ClinVar PMID:28492532 NCBI chr 9:82,053,581...82,066,047
Ensembl chr 9:82,053,581...82,066,047
JBrowse link
Back Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr2a 5-hydroxytryptamine receptor 2A IDA RGD PMID:17268262 RGD:1624379 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:12227717 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
Cancer Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcr4 C-X-C motif chemokine receptor 4 IEP
IMP
mRNA,protein:increased expression:spinal cord: RGD PMID:28108674, PMID:28638088 RGD:13463594, RGD:13838657 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Mir338 microRNA 338 IEP RNA:decreased expression:spinal cord: RGD PMID:28108674 RGD:13463594 NCBI chr10:109,195,251...109,195,316 JBrowse link
G Tmprss2 transmembrane serine protease 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25734995 NCBI chr11:38,063,914...38,103,406
Ensembl chr11:38,063,915...38,103,290
JBrowse link
Chest Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:2563132 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Mefv MEFV innate immuity regulator, pyrin ISO ClinVar Annotator: match by term: Chest pain ClinVar PMID:9288094, PMID:9288758, PMID:9781020, PMID:10024914, PMID:10090880, PMID:10364520, PMID:10447272, PMID:10612841, PMID:10737995, PMID:10787449, PMID:10905662, PMID:11017802, PMID:11464248, PMID:11468188, PMID:11938447, PMID:12105243, PMID:12401847, PMID:12687559, PMID:12908875, PMID:14727057, PMID:15643295, PMID:15942916, PMID:15951859, PMID:16179998, PMID:16255051, PMID:16439335, PMID:16627024, PMID:16785446, PMID:16889173, PMID:17331080, PMID:17489852, PMID:18353061, PMID:19151977, PMID:19790133, PMID:19863562, PMID:19967574, PMID:20008920, PMID:20437121, PMID:20483145, PMID:20534143, PMID:20669279, PMID:21290976, PMID:21600797, PMID:21623663, PMID:22037353, PMID:23334425, PMID:23907647, PMID:23973724, PMID:24318677, PMID:25741868, PMID:26467025, PMID:26510601, PMID:27030597, PMID:27513391, PMID:28492532, PMID:30171907, PMID:30311386 NCBI chr10:12,045,813...12,056,229
Ensembl chr10:12,046,541...12,056,311
JBrowse link
Chronic Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor IEP protein:increased expression:frontal cortex, neuron
mRNA:decreased expression:anterior cingulate cortex
RGD PMID:11360665, PMID:24518228 RGD:5684922, RGD:10059366 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Hfe homeostatic iron regulator ISO DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30657865 RGD:14746966 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Myh11 myosin heavy chain 11 ISO ClinVar Annotator: match by term: Chronic pain ClinVar PMID:30311386 NCBI chr10:764,421...859,184
Ensembl chr10:764,421...859,184
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IEP protein:increased expression:frontal cortex, neuron RGD PMID:11360665 RGD:5684922 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Scn9a sodium voltage-gated channel alpha subunit 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21634377 NCBI chr 3:52,583,953...52,664,209
Ensembl chr 3:52,583,951...52,664,209
JBrowse link
G Tlr2 toll-like receptor 2 ISO RGD PMID:24204973 RGD:8553185 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 ISO RGD PMID:24204973 RGD:8553185 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Ush2a usherin ISO ClinVar Annotator: match by term: Chronic pain ClinVar PMID:9624053, PMID:10090909, PMID:10729113, PMID:10775529, PMID:10909849, PMID:11311042, PMID:11402400, PMID:12112664, PMID:12525556, PMID:14970843, PMID:15025721, PMID:15325563, PMID:15326663, PMID:17296898, PMID:17405132, PMID:18641288, PMID:18665195, PMID:19881469, PMID:20145675, PMID:20301515, PMID:21174530, PMID:21234346, PMID:22495311, PMID:22581970, PMID:23352160, PMID:24033266, PMID:24088041, PMID:24160897, PMID:24607488, PMID:24944099, PMID:25097241, PMID:25404053, PMID:25649381, PMID:25741868, PMID:26633545, PMID:26872967, PMID:28041643, PMID:28492532, PMID:29953849, PMID:30718709 NCBI chr13:106,750,738...107,434,195
Ensembl chr13:106,751,625...107,427,329
JBrowse link
Dysmenorrhea term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avp arginine vasopressin ISO CTD Direct Evidence: marker/mechanism CTD PMID:10440088 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta ISO protein:increased expression:ectopic endometrium: RGD PMID:22572543 RGD:9588664 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:10440088 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
Exertional Myalgia, Muscle Stiffness and Myoglobinuria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmd dystrophin ISO ClinVar Annotator: match by term: Exertional myalgia, muscle stiffness and myoglobinuria ClinVar PMID:2677830, PMID:7981747, PMID:8223790, PMID:8652023, PMID:8902723, PMID:9170393, PMID:9224530, PMID:11404124, PMID:11879882, PMID:14600829, PMID:19367636, PMID:21104870, PMID:23092449, PMID:23263593, PMID:23756440, PMID:25637381, PMID:26467025, PMID:28492532, PMID:28580208 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
Eye Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:4327920 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
familial episodic pain syndrome 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 ISO ClinVar Annotator: match by term: Familial episodic pain syndrome 1 OMIM
ClinVar
PMID:20547126, PMID:25741868 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link
familial episodic pain syndrome 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn10a sodium voltage-gated channel alpha subunit 10 ISO ClinVar Annotator: match by term: Episodic pain syndrome, familial, 2
ClinVar Annotator: match by OMIM:615551
OMIM
ClinVar
PMID:23115331, PMID:24998131, PMID:25053638, PMID:25085921, PMID:25741868, PMID:26733327, PMID:28078312, PMID:28492532, PMID:29247119, PMID:30135145 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
familial episodic pain syndrome 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn11a sodium voltage-gated channel alpha subunit 11 ISO ClinVar Annotator: match by term: Episodic pain syndrome, familial, 3
ClinVar Annotator: match by OMIM:615552
OMIM
ClinVar
PMID:24207120, PMID:24776970, PMID:25741868, PMID:28298626, PMID:28492532, PMID:30046661, PMID:30557356 NCBI chr 8:128,450,793...128,527,510
Ensembl chr 8:128,450,801...128,521,109
JBrowse link
Headache term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ampd1 adenosine monophosphate deaminase 1 ISO ClinVar Annotator: match by term: Headache ClinVar PMID:25741868, PMID:30311386 NCBI chr 2:205,568,934...205,589,961
Ensembl chr 2:205,568,935...205,590,021
JBrowse link
G Ano5 anoctamin 5 ISO ClinVar Annotator: match by term: Headaches ClinVar PMID:9673985, PMID:20096397, PMID:21186264, PMID:21739273, PMID:21820307, PMID:22194990, PMID:22336395, PMID:22402862, PMID:22499103, PMID:22742934, PMID:22980763, PMID:23041008, PMID:23606453, PMID:23607914, PMID:24022920, PMID:24232312, PMID:24843231, PMID:25741868, PMID:25891276, PMID:26467025, PMID:27708273, PMID:28492532, PMID:30311386 NCBI chr 1:106,873,580...106,971,769
Ensembl chr 1:106,896,790...106,968,885
JBrowse link
G Col4a2 collagen type IV alpha 2 chain ISO ClinVar Annotator: match by term: Headache ClinVar PMID:30311386 NCBI chr16:83,386,388...83,522,169
Ensembl chr16:83,387,364...83,438,561
JBrowse link
G Col4a5 collagen type IV alpha 5 chain ISO ClinVar Annotator: match by term: Headache ClinVar PMID:30311386 NCBI chr  X:112,769,595...112,983,720
Ensembl chr  X:112,769,645...112,983,685
JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10864982 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO ClinVar Annotator: match by term: Headache ClinVar PMID:30311386 NCBI chr 1:21,748,201...21,813,205
Ensembl chr 1:21,748,261...21,813,371
JBrowse link
G Fkrp fukutin related protein ISO ClinVar Annotator: match by term: Headaches ClinVar PMID:11741828, PMID:12666124, PMID:14647208, PMID:15060126, PMID:15574464, PMID:15580560, PMID:15833432, PMID:15886712, PMID:16634037, PMID:16786213, PMID:17554798, PMID:18060779, PMID:18593008, PMID:18639457, PMID:19820980, PMID:19835634, PMID:19900540, PMID:21220724, PMID:21228398, PMID:22264518, PMID:22981120, PMID:23576288, PMID:23591631, PMID:24033266, PMID:24447024, PMID:25048216, PMID:25560911, PMID:25741868, PMID:26363967, PMID:26467025, PMID:26574668, PMID:26833294, PMID:28492532, PMID:30311386 NCBI chr 1:78,733,461...78,740,803
Ensembl chr 1:78,733,508...78,739,107
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12910066 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7537110 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:7080326 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 ISO ClinVar Annotator: match by term: Headache ClinVar PMID:30311386 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Tmprss3 transmembrane serine protease 3 ISO ClinVar Annotator: match by term: Headaches ClinVar PMID:11907649, PMID:12920079, PMID:15447792, PMID:17981648, PMID:19170735, PMID:21534946, PMID:21786053, PMID:24033266, PMID:25741868, PMID:26036852, PMID:26408194, PMID:28263784, PMID:30311386 NCBI chr20:9,910,522...9,929,705
Ensembl chr20:9,910,522...9,929,705
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO human protein in rat model RGD PMID:21036476 RGD:5131274 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Tpo thyroid peroxidase ISO ClinVar Annotator: match by term: Headache ClinVar PMID:1401057, PMID:15745925, PMID:17468186, PMID:23512414, PMID:27373559, PMID:27617131, PMID:30240412, PMID:30311386 NCBI chr 6:49,020,918...49,089,855
Ensembl chr 6:49,021,044...49,089,855
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein ISO DNA:missense mutation: :p.H611R (human) RGD PMID:17719176 RGD:8694403 NCBI chr14:78,640,707...78,665,224
Ensembl chr14:78,640,620...78,665,966
JBrowse link
Hyperalgesia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase treatment IMP RGD PMID:24890317 RGD:9588557 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Adk adenosine kinase IMP associated with diabetic neuropathies; RGD PMID:11423084, PMID:9932716 RGD:6482662, RGD:6482666 NCBI chr15:3,033,535...3,435,888
Ensembl chr15:3,033,495...3,435,888
JBrowse link
G Adm adrenomedullin IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:17043245, PMID:17043245 RGD:1625316 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adora1 adenosine A1 receptor IDA associated with Spinal Cord Injuries RGD PMID:20065990 RGD:5129094 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adra1a adrenoceptor alpha 1A IEP associated with Diabetes Mellitus, Experimental; mRNA:increased expression:dorsal root ganglion RGD PMID:10841349 RGD:5688377 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Adra2a adrenoceptor alpha 2A IMP RGD PMID:17959985 RGD:6480488 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Adra2c adrenoceptor alpha 2C IMP RGD PMID:20007733 RGD:6893568 NCBI chr14:80,730,307...80,732,010
Ensembl chr14:80,730,307...80,732,010
JBrowse link
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:19283893 RGD:5129125 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Ager advanced glycosylation end product-specific receptor treatment IMP
ISO
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:25014009, PMID:25014009, PMID:24077211 RGD:8695980, RGD:7364865 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:9613798 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Aif1 allograft inflammatory factor 1 IEP
ISO
associated with Alcohol-Induced Disorders, Nervous System; protein:increased expression:spinal cord (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:27093858, PMID:17284346 RGD:2313035 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B IDA associated with Hyperglycemia RGD PMID:12505670 RGD:1626082 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type ISO CTD Direct Evidence: marker/mechanism CTD PMID:12582831 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12582831 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Ano3 anoctamin 3 IMP RGD PMID:23872594 RGD:9681745 NCBI chr 3:101,843,516...102,203,368
Ensembl chr 3:101,840,630...102,151,489
JBrowse link
G Anxa1 annexin A1 IMP
IEP
protein:increased expression:dorsal root ganglion RGD PMID:9222544, PMID:21990306 RGD:2306950, RGD:7421656 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Aqp4 aquaporin 4 IEP associated with Spinal Cord Injuries;mRNA,protein:increased expression:brain,spinal cord: RGD PMID:16219025 RGD:8695957 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Avp arginine vasopressin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9613798 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Bace1 beta-secretase 1 IMP RGD PMID:28012171 RGD:13782150 NCBI chr 8:50,140,092...50,162,388
Ensembl chr 8:50,139,997...50,162,361
JBrowse link
G Bdkrb1 bradykinin receptor B1 IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:17989505, PMID:19300402, PMID:19815945, PMID:12927641, PMID:12637034 RGD:1579989, RGD:7241581 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Bdkrb2 bradykinin receptor B2 IMP
ISO
CTD Direct Evidence: marker/mechanism
associated with Diabetic Neuropathy
CTD PMID:17989505, PMID:19300402, PMID:19815945, PMID:10188975, PMID:19300402 RGD:4891040, RGD:2313332 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Bdnf brain-derived neurotrophic factor IMP
IEP
IDA
ISO
associated with Peripheral Nerve Injuries;
associated with inflammation;protein:increased expression:dorsal root ganglion:
associated with Sciatic Neuropathy;
associated with Pancreatitis, Chronic;
RGD PMID:11425916, PMID:21958434, PMID:10779676, PMID:12435470, PMID:21864655, PMID:21499209, PMID:12470870 RGD:8657088, RGD:8657122, RGD:8657114, RGD:8657101, RGD:8657099, RGD:8657093, RGD:8657091 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 IEP RGD PMID:23665054 RGD:11560531 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G C3 complement C3 IEP associated with Sciatic Neuropathy;mRNA, protein:increased expression:spinal cord RGD PMID:23588254 RGD:7401259 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B IDA RGD PMID:17567797 RGD:1626313 NCBI chr 3:1,740,026...1,924,959
Ensembl chr 3:1,740,024...1,924,827
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H ISO CTD Direct Evidence: marker/mechanism CTD PMID:19577366, PMID:30552955 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I IMP RGD PMID:17112407 RGD:15003199 NCBI chr 7:121,521,787...121,619,300
Ensembl chr 7:121,511,097...121,619,283
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11245671, PMID:17881535, PMID:24133248 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Calca calcitonin-related polypeptide alpha IEP
ISO
associated with inflammation;protein:increased expression:dorsal root ganglion:
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:12787826, PMID:12855330, PMID:15265675, PMID:27093858, PMID:21958434 RGD:8657122 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha ISO
IMP
CTD Direct Evidence: marker/mechanism CTD PMID:20053885, PMID:18042863 RGD:7240711 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Capn2 calpain 2 treatment IMP associated with Peripheral Nerve Injuries RGD PMID:25150005 RGD:13792585 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Cartpt CART prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:21167239 NCBI chr 2:30,125,249...30,127,408
Ensembl chr 2:30,125,249...30,127,269
JBrowse link
G Cat catalase treatment IEP
IMP
RGD PMID:23952340, PMID:23658840 RGD:9479063, RGD:9479069 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cck cholecystokinin IDA RGD PMID:15647484 RGD:1626108 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Cckbr cholecystokinin B receptor IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:11880531, PMID:15647484 RGD:1626108 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IDA
ISO
IEP
IMP
CTD Direct Evidence: marker/mechanism
protein:increased expression:dorsal root ganglion, spinal cord (rat)
CTD PMID:17881535, PMID:18419759, PMID:21712071, PMID:20737477, PMID:22531750 RGD:2307043, RGD:8548873, RGD:8548848, RGD:8548845 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP
IDA
mRNA:increased expression:dorsal root ganglion (rat) RGD PMID:18076762, PMID:18656466 RGD:4890034, RGD:2303121 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 IMP
ISO
IEP
associated with Intervertebral disc disease;
associated with Demyelinating Diseases;
associated with Sciatic Neuropathy;
protein:increased expression:dorsal horn of spinal cord:
associated with Bone Neoplasms;protein:increased expression:spinal cord:
RGD PMID:18419759, PMID:24462503, PMID:18076762, PMID:24907405, PMID:22721162, PMID:23511129 RGD:2307043, RGD:8661788, RGD:4890034, RGD:8661781, RGD:8548831, RGD:8661772
G Ccr5 C-C motif chemokine receptor 5 IEP
ISO
IMP
mRNA:increased expression:dorsal root ganglion (rat)
associated with Spinal Cord Injuries
RGD PMID:18076762, PMID:22033364, PMID:23147416, PMID:24589480 RGD:4890034, RGD:8551820, RGD:8551809, RGD:8551795 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cfl1 cofilin 1 IEP protein:increased phosphorylation:dorsal root ganglion (rat) RGD PMID:24962708 RGD:11570412 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:17572696 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:17572696, PMID:18664590 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Comt catechol-O-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28195063, PMID:20726980 RGD:8662326 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Crcp CGRP receptor component IEP RGD PMID:12895509 RGD:727768 NCBI chr12:30,125,237...30,160,857
Ensembl chr12:30,125,168...30,180,115
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28434951 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO associated with Sciatic Neuropathy; RGD PMID:24253780 RGD:11039470 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Csk C-terminal Src kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16769263 NCBI chr 8:62,405,714...62,424,707
Ensembl chr 8:62,405,715...62,424,303
JBrowse link
G Ctss cathepsin S IMP
ISO
associated with Arthritis, Experimental
associated with Colitis
RGD PMID:22213084, PMID:21802389 RGD:5686870, RGD:5686873 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 treatment IDA
IEP
associated with Arthritis, Experimental RGD PMID:19249394, PMID:22647647 RGD:2304251, RGD:9491779 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO
IEP
IMP
associated with Arthritis, Experimental;protein:increased expression:lumbar spinal cord
associated with Inflammation
associated with Sciatic Neuropathy
associated with Bone Neoplasms
RGD PMID:20609517, PMID:22647647, PMID:16324111, PMID:20524966, PMID:19959384, PMID:20736819 RGD:4891885, RGD:9491779, RGD:9387859, RGD:9354422, RGD:4891942, RGD:4892020 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IDA RGD PMID:28638088 RGD:13838657 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IMP RGD PMID:19283893 RGD:5129125 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 treatment IMP RGD PMID:28638088, PMID:30142543 RGD:13838657, RGD:13838658 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cybb cytochrome b-245 beta chain ISO associated with Spinal Cord Injuries; RGD PMID:20679217 RGD:11040629 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 IDA associated with Diabetic neuropathies; RGD PMID:20531396 RGD:7257680 NCBI chr10:56,625,845...56,655,543
Ensembl chr10:56,627,411...56,653,599
JBrowse link
G Dnmt1 DNA methyltransferase 1 IMP RGD PMID:21682946 RGD:9588311 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Drd3 dopamine receptor D3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20433900 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Dusp1 dual specificity phosphatase 1 treatment IEP
IDA
associated with Sciatic Neuropathy RGD PMID:22901764, PMID:22540262 RGD:7771531, RGD:7771574 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp6 dual specificity phosphatase 6 treatment IEP associated with Sciatic Neuropathy RGD PMID:22901764 RGD:7771531 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Edn1 endothelin 1 susceptibility ISO mRNA:increased expression:paw skin (mouse)
CTD Direct Evidence: marker/mechanism
CTD PMID:19429182, PMID:23347081, PMID:15664691 RGD:8661716, RGD:8661735 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 treatment IMP RGD PMID:20392816 RGD:9685429 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:25263804 RGD:9588307 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Epha4 Eph receptor A4 IMP associated with spinal cord injuries; RGD PMID:16959251 RGD:5688783 NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458
JBrowse link
G Ephx2 epoxide hydrolase 2 IMP RGD PMID:16962614 RGD:5688387 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Esr1 estrogen receptor 1 ISO RGD PMID:19285805 RGD:8553066 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 IDA
ISO
RGD PMID:17056036, PMID:19285805 RGD:5508846, RGD:8553066 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G F2 coagulation factor II ISO associated with Sciatic Neuropathy RGD PMID:16251448 RGD:7387272 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F2r coagulation factor II (thrombin) receptor severity ISO
IDA
RGD PMID:19674841, PMID:11877315, PMID:12717003 RGD:7387269, RGD:7387271, RGD:7387270 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP
ISO
protein:increased expression:dorsal horn of spinal cord, neuron
CTD Direct Evidence: marker/mechanism
CTD PMID:27093858, PMID:22160634 RGD:9999169 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gal galanin and GMAP prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:12787826 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Gdnf glial cell derived neurotrophic factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20457222 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gfap glial fibrillary acidic protein IEP
ISO
associated with Spinal Cord Injuries;mRNA,protein:increased expression:brain,spinal cord:
CTD Direct Evidence: marker/mechanism
CTD PMID:27093858, PMID:16219025 RGD:8695957 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gfra1 GDNF family receptor alpha 1 IDA RGD PMID:16464682 RGD:6218969 NCBI chr 1:279,203,046...279,572,789 JBrowse link
G Gja1 gap junction protein, alpha 1 treatment IMP
IEP
associated with Sciatic Neuropathy RGD PMID:24631560, PMID:23374942 RGD:8662447, RGD:8662456 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A IDA RGD PMID:29758384 RGD:13792698 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B treatment ISO
IMP
CTD Direct Evidence: marker/mechanism CTD PMID:20042082, PMID:24204988 RGD:13210755 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 treatment
severity
IDA
IMP
IEP
associated with bone cancer
associated with Complex Regional Pain Syndromes
RGD PMID:26935064, PMID:22796071, PMID:25466829, PMID:26064176 RGD:13513996, RGD:13792780, RGD:13514049, RGD:13514046 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Grm8 glutamate metabotropic receptor 8 ISO RGD PMID:17113112 RGD:6771186 NCBI chr 4:54,474,344...55,409,526
Ensembl chr 4:54,474,136...55,407,922
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP associated with Limb Ischemia;protein:increased expression:foot muscle, plantar RGD PMID:18691814 RGD:9068903 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgb1 high mobility group box 1 treatment IEP
IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:27474498, PMID:24077211, PMID:30142543 RGD:7364865, RGD:13838658 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hoxd1 homeo box D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21151121 NCBI chr 3:61,685,619...61,687,758
Ensembl chr 3:61,685,619...61,687,758
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IDA
ISO
associated with Diabetic neuropathies;
CTD Direct Evidence: marker/mechanism
CTD PMID:17888573, PMID:18930597, PMID:20531396 RGD:7257680 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IMP
IDA
RGD PMID:21693130, PMID:21843960 RGD:6480665, RGD:6482179 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G Igf1 insulin-like growth factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:9452187 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il10 interleukin 10 treatment IEP
ISO
IDA
associated with Sciatic Neuropathy
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:7582491, PMID:17174526, PMID:23957449, PMID:24077211, PMID:22820166 RGD:7364792, RGD:7364865, RGD:7364827 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il13 interleukin 13 treatment ISO RGD PMID:11399514 RGD:8549555 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il17a interleukin 17A treatment IDA
IMP
RGD PMID:23192794, PMID:23246025 RGD:9068942, RGD:9222699 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il18 interleukin 18 treatment IMP associated with Peripheral Nerve Injuries RGD PMID:19036970 RGD:8655929 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:12727271 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta IDA
ISO
CTD Direct Evidence: marker/mechanism
associated with Peripheral Nerve Injuries
CTD PMID:7582491, PMID:10401557, PMID:12727271, PMID:17320857, PMID:20937348, PMID:27093858, PMID:15317861, PMID:8741165, PMID:23159984, PMID:22265659 RGD:1626676, RGD:7401209, RGD:7175548, RGD:6482671 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r1 interleukin 1 receptor type 1 IMP
ISO
RGD PMID:19022353, PMID:11585580 RGD:8662898, RGD:8662903 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il1rn interleukin 1 receptor antagonist severity
treatment
IDA
ISO
IMP
CTD Direct Evidence: marker/mechanism|therapeutic
associated with Arthritis, Experimental; rat model treated with human protein
CTD PMID:8864563, PMID:15317861, PMID:17174526, PMID:20937348, PMID:23092240, PMID:10903985, PMID:17959986, PMID:22933159 RGD:6909165, RGD:8549800, RGD:7401210, RGD:6909175 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il2 interleukin 2 treatment IMP
IDA
IEP
associated with Sciatic Neuropathy; mRNA,protein:increased expression:spinal cord: RGD PMID:12755376, PMID:18423867, PMID:22189457 RGD:8662973, RGD:8662980, RGD:8662977 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il6 interleukin 6 IEP
ISO
associated with Foot Injuries; protein:increased expression:serum:
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:dorsal root ganglion
CTD PMID:7582491, PMID:10401557, PMID:18652822, PMID:18988309, PMID:23953943 RGD:8662979, RGD:10402830 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor IEP mRNA:increased expression:dorsal root ganglion RGD PMID:23953943 RGD:10402830 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Insr insulin receptor treatment ISO associated with Diabetic Neuropathies
CTD Direct Evidence: marker/mechanism
CTD PMID:18331706, PMID:23511693 RGD:10403050 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Itga1 integrin subunit alpha 1 IMP knock-down using a specific monoclonal antibody or RNAi
PGE2-induced
RGD PMID:15836982, PMID:14984413 RGD:2302139, RGD:2302389 NCBI chr 2:47,127,403...47,281,387
Ensembl chr 2:47,127,219...47,281,421
JBrowse link
G Itga2 integrin subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18234883 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Itga3 integrin subunit alpha 3 IMP knock-down using a specific monoclonal antibody or RNAi RGD PMID:14984413, PMID:15836982 RGD:2302389, RGD:2302139 NCBI chr10:82,855,841...82,887,755
Ensembl chr10:82,855,613...82,887,497
JBrowse link
G Itga5 integrin subunit alpha 5 IMP epinephrine-induced
knock-down using a specific monoclonal antibody or RNAi
RGD PMID:14984413, PMID:15836982 RGD:2302389, RGD:2302139 NCBI chr 7:144,970,444...144,993,652
Ensembl chr 7:144,970,444...144,993,652
JBrowse link
G Itgb1 integrin subunit beta 1 IMP knock-down using a specific monoclonal antibody or RNAi RGD PMID:14984413, PMID:15836982 RGD:2302389, RGD:2302139 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 IEP RGD PMID:25972297 RGD:13793383 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Jak2 Janus kinase 2 treatment IMP
ISO
associated with Diabetic Neuropathies RGD PMID:18636982, PMID:23511693 RGD:6483031, RGD:10403050 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jak3 Janus kinase 3 treatment IEP RGD PMID:21434883 RGD:11533942 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668
JBrowse link
G Kcnc4 potassium voltage-gated channel subfamily C member 4 IMP RGD PMID:17855600 RGD:10411908 NCBI chr 2:210,220,908...210,241,447
Ensembl chr 2:210,220,908...210,241,455
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 ISO RGD PMID:16675954 RGD:9831112 NCBI chr13:107,690,111...107,886,476
Ensembl chr13:107,690,087...107,886,476
JBrowse link
G Kcnq3 potassium voltage-gated channel subfamily Q member 3 IEP associated with Bone Neoplasms;protein:decreased expression:dorsal root ganglia (rat) RGD PMID:23352759 RGD:9686417 NCBI chr 7:106,714,479...107,009,639
Ensembl chr 7:106,717,229...107,009,330
JBrowse link
G Kmo kynurenine 3-monooxygenase treatment IMP RGD PMID:26524415 RGD:13703043 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kng2 kininogen 2 IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:2010815, PMID:2128375, PMID:3061568, PMID:7493622, PMID:7582491, PMID:7881729, PMID:9714424, PMID:9720808, PMID:10401557, PMID:10499367, PMID:10543429, PMID:15626726, PMID:16259764, PMID:16793879, PMID:18234883, PMID:21521205, PMID:20868656 RGD:11059894 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha IEP RGD PMID:23665054 RGD:11560531 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 onset ISO RGD PMID:19427893 RGD:7495807 NCBI chr10:45,089,455...45,110,802
Ensembl chr10:47,182,433...47,203,753
JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12941468, PMID:27093858 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12941468, PMID:27093858 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17237256 NCBI chr10:47,768,592...47,775,130
Ensembl chr10:47,766,680...47,775,055
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mc1r melanocortin 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19996949 NCBI chr19:56,215,420...56,219,987 JBrowse link
G Mc4r melanocortin 4 receptor IEP protein:increased expression:dorsal root ganglia (rat) RGD PMID:20081244 RGD:6484233 NCBI chr18:62,612,838...62,614,725
Ensembl chr18:62,612,838...62,614,725
JBrowse link
G Men1 menin 1 IEP associated with Sciatic Neuropathy;protein:increased expression:spinal cord dorsal horn (rat) RGD PMID:20369282 RGD:9589142 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
G Mfn2 mitofusin 2 IEP
ISO
mRNA:decreased expression:spinal cord (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:28587902, PMID:28587902 RGD:12910704 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mir15b microRNA 15b IDA RGD PMID:28012171 RGD:13782150 NCBI chr 2:165,605,923...165,606,020
Ensembl chr 2:165,605,923...165,606,020
JBrowse link
G Mir381 microRNA 381 treatment IDA RGD PMID:30142543 RGD:13838658 NCBI chr 6:133,876,615...133,876,675
Ensembl chr 6:133,876,586...133,876,693
JBrowse link
G Mir96 microRNA 96 treatment IDA associated with Sciatic Neuropathy RGD PMID:24234845 RGD:11553932 NCBI chr 4:57,463,366...57,463,471
Ensembl chr 4:57,463,366...57,463,471
JBrowse link
G Mmp3 matrix metallopeptidase 3 IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:18754875, PMID:22056600 RGD:8693664 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mpz myelin protein zero ISO CTD Direct Evidence: marker/mechanism CTD PMID:16676325 NCBI chr13:89,524,204...89,530,070
Ensembl chr13:89,524,329...89,530,068
JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:24382350 RGD:10040983 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Nefh neurofilament heavy treatment IEP RGD PMID:21071147 RGD:27226885 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Ngf nerve growth factor treatment ISO
IMP
IDA
associated with Cystitis
CTD Direct Evidence: marker/mechanism
associated with Peripheral Nerve Injuries;
CTD PMID:20457222, PMID:16203088, PMID:11425916, PMID:22839415, PMID:18448607 RGD:7242799, RGD:8657088, RGD:7242849, RGD:7242803 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ngfr nerve growth factor receptor treatment IMP associated with Brachial Plexus Neuropathies RGD PMID:23324933 RGD:10413898 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nlgn2 neuroligin 2 IMP RGD PMID:23891900 RGD:9831150 NCBI chr10:56,431,586...56,444,847
Ensembl chr10:56,431,573...56,444,847
JBrowse link
G Nos1 nitric oxide synthase 1 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:19300402, PMID:23909597 RGD:7257597 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17989504, PMID:19300402 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npy neuropeptide Y treatment IEP associated with Sciatic Neuropathy RGD PMID:19556004 RGD:10448929 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Nrg1 neuregulin 1 IEP associated with Sciatic Neuropathy RGD PMID:22212401 RGD:10449019 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Ntf3 neurotrophin 3 ISO CTD Direct Evidence: therapeutic CTD PMID:15659614 NCBI chr 4:158,636,883...158,705,886
Ensembl chr 4:158,636,884...158,705,886
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 IMP RGD PMID:17667845, PMID:20351485 RGD:5144120, RGD:5684352 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO
IEP
associated with inflammation;protein:increased expression:dorsal root ganglion: RGD PMID:12470870, PMID:21958434 RGD:8657091, RGD:8657122 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Ntsr1 neurotensin receptor 1 IDA RGD PMID:22396077 RGD:9743902 NCBI chr 3:175,982,313...176,046,345
Ensembl chr 3:175,885,894...176,046,345
JBrowse link
G Oprk1 opioid receptor, kappa 1 treatment IMP associated with Diabetes Mellitus, Experimental; RGD PMID:16924480 RGD:9834947 NCBI chr 5:13,742,655...13,760,460
Ensembl chr 5:13,744,658...13,760,305
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IEP associated with Sciatic Neuropathy;mRNA:increased expression:spinal cord lumbar segment,dorsal root ganglion: RGD PMID:12106803 RGD:9835017 NCBI chr 3:177,223,779...177,231,663
Ensembl chr 3:177,225,737...177,231,663
JBrowse link
G Oprm1 opioid receptor, mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17996026 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
JBrowse link
G P2rx2 purinergic receptor P2X 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19383439 NCBI chr12:52,397,666...52,401,005
Ensembl chr12:52,397,792...52,401,015
JBrowse link
G P2rx3 purinergic receptor P2X 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19383439 NCBI chr 3:72,403,992...72,447,801
Ensembl chr 3:72,403,993...72,447,801
JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO
IMP
RGD PMID:20398327, PMID:20136836 RGD:6480525, RGD:6480526 NCBI chr 2:149,440,807...149,482,592
Ensembl chr 2:149,441,598...149,444,548
JBrowse link
G Pawr pro-apoptotic WT1 regulator treatment IDA RGD PMID:17179954 RGD:9835416 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068
JBrowse link
G Pdyn prodynorphin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17670969 NCBI chr 3:122,194,327...122,206,671
Ensembl chr 3:122,194,329...122,206,671
JBrowse link
G Penk proenkephalin treatment ISO associated with Diabetes Mellitus, Experimental; RGD PMID:23235561 RGD:10003116 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Pla2g4a phospholipase A2 group IVA IMP RGD PMID:16203828 RGD:1642461 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Pnoc prepronociceptin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12665541, PMID:19231294 NCBI chr15:48,805,841...48,833,071
Ensembl chr15:48,805,228...48,833,285
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha IMP RGD PMID:26732138 RGD:11572421 NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664
JBrowse link
G Prkcb protein kinase C, beta IDA associated with inflammation;protein:increased activity:spinal cord RGD PMID:16360284 RGD:1625519 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prkce protein kinase C, epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:11738263, PMID:12582831, PMID:20457222 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Prkcg protein kinase C, gamma treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:19955894, PMID:27093858, PMID:12560106 RGD:28867224 NCBI chr 1:64,407,098...64,433,698
Ensembl chr 1:64,407,114...64,433,636
JBrowse link
G Prkcz protein kinase C, zeta ISO CTD Direct Evidence: marker/mechanism CTD PMID:27899695 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 treatment ISO RGD PMID:14973199 RGD:7775058 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Prok2 prokineticin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16793879 NCBI chr 4:132,157,556...132,171,244
Ensembl chr 4:132,157,556...132,171,153
JBrowse link
G Prokr1 prokineticin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16793879 NCBI chr 4:119,375,790...119,386,551
Ensembl chr 4:119,375,778...119,386,590
JBrowse link
G Ptafr platelet-activating factor receptor treatment IMP RGD PMID:16925995 RGD:10041052 NCBI chr 5:150,746,284...150,775,675
Ensembl chr 5:150,754,021...150,775,672
JBrowse link
G Ptger1 prostaglandin E receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11375261 NCBI chr19:24,799,422...24,803,373
Ensembl chr19:24,800,072...24,803,373
JBrowse link
G Ptger3 prostaglandin E receptor 3 IEP protein:increased expression:lumbar spinal cord dorsal horn (rat) RGD PMID:17413918 RGD:5688169 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
G Ptger4 prostaglandin E receptor 4 treatment IMP RGD PMID:20423341 RGD:10003041 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
JBrowse link
G Ptges3 prostaglandin E synthase 3 IMP RGD PMID:16192391 RGD:5688057 NCBI chr 7:2,479,267...2,497,024
Ensembl chr 7:2,479,311...2,497,013
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IEP
ISO
protein:increased expression:spinal cord
CTD Direct Evidence: marker/mechanism
CTD PMID:17989504, PMID:17413918 RGD:5688169 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:17112505, PMID:17989504, PMID:15464832 RGD:5688224 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pthlh parathyroid hormone-like hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:16769263 NCBI chr 4:181,663,425...181,674,181 JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18976650 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rgs4 regulator of G-protein signaling 4 treatment IMP associated with lesion of sciatic nerve RGD PMID:27641322 RGD:13524513 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:16545521, PMID:19070548 RGD:6484253 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Scn11a sodium voltage-gated channel alpha subunit 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23264124 NCBI chr 8:128,450,793...128,527,510
Ensembl chr 8:128,450,801...128,521,109
JBrowse link
G Sin3a SIN3 transcription regulator family member A IEP associated with Arthritis, Experimental;mRNA:decreased expression:spinal cord, neuron RGD PMID:17553988 RGD:9495916 NCBI chr 8:61,748,590...61,803,314
Ensembl chr 8:61,762,768...61,803,099
JBrowse link
G Slc12a5 solute carrier family 12 member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20086212 NCBI chr 3:161,433,303...161,465,078
Ensembl chr 3:161,425,988...161,462,879
JBrowse link
G Slc17a8 solute carrier family 17 member 8 IEP protein:increased expression:dorsal horn of spinal cord, neuron RGD PMID:22160634 RGD:9999169 NCBI chr 7:30,215,231...30,274,993
Ensembl chr 7:30,216,104...30,274,984
JBrowse link
G Sparc secreted protein acidic and cysteine rich ISO CTD Direct Evidence: marker/mechanism CTD PMID:20714283 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Stat3 signal transducer and activator of transcription 3 treatment IMP RGD PMID:24098399 RGD:8694290 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Syn2 synapsin II ISO CTD Direct Evidence: marker/mechanism CTD PMID:18701217 NCBI chr 4:147,037,179...147,195,096
Ensembl chr 4:147,037,179...147,195,096
JBrowse link
G Tac1 tachykinin, precursor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8864563, PMID:9714424, PMID:10499367, PMID:12351280, PMID:12787826, PMID:15626726, PMID:16259764, PMID:18234883, PMID:19231294 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tacr1 tachykinin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15964684, PMID:17123731 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 IMP associated with Experimental Pancreatitis, Chronic RGD PMID:26645248 RGD:14995470 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Thbd thrombomodulin treatment ISO associated with Inflammation
CTD Direct Evidence: therapeutic
CTD PMID:27474498, PMID:24004409 RGD:11038687 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Tlr2 toll-like receptor 2 ISO
IDA
RGD PMID:17355971, PMID:24204973 RGD:8553059, RGD:8553185 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 IMP
ISO
RGD PMID:20714435, PMID:24204973, PMID:15809417 RGD:4144070, RGD:8553185, RGD:7815040 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor IMP
ISO
IDA
IEP
CTD Direct Evidence: marker/mechanism
associated with Diabetic Neuropathies;
mRNA,protein:increased expression:spinal cord:
protein:increased expression:lumbar vertebra:
CTD PMID:7582491, PMID:7881729, PMID:10401557, PMID:12727271, PMID:16472913, PMID:17320857, PMID:18463260, PMID:18582539, PMID:20383154, PMID:26141506, PMID:27093858, PMID:16675114, PMID:21104419, PMID:17304130, PMID:10825476, PMID:18790011, PMID:17459378, PMID:16675114 RGD:7387300, RGD:7401179, RGD:7394757, RGD:7394741, RGD:7394737, RGD:7387302, RGD:7387300 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO CTD Direct Evidence: therapeutic CTD PMID:16769263 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A treatment IMP
IEP
ISO
associated with Sciatic Neuropathy RGD PMID:12752784, PMID:22652595, PMID:21712071, PMID:24257399, PMID:20417692, PMID:21145890 RGD:5130913, RGD:8661750, RGD:8548873, RGD:8661737, RGD:8661726, RGD:5130939 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO
IMP
associated with Sciatic Neuropathy RGD PMID:18463260, PMID:22652595 RGD:5130960, RGD:8661750 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IMP
ISO
associated with Peripheral Nerve Injuries;
CTD Direct Evidence: marker/mechanism
CTD PMID:18234885, PMID:21481532, PMID:23523557, PMID:18954467 RGD:10043618 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 IMP associated with Inflammation RGD PMID:19439599 RGD:7247605 NCBI chr 8:103,503,982...103,554,905
Ensembl chr 8:103,503,985...103,554,468
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 IMP RGD PMID:19439599 RGD:7247605 NCBI chr 8:6,811,543...6,917,534
Ensembl chr 8:6,811,543...6,917,535
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 IEP
ISO
associated with inflammation;protein:increased expression:dorsal root ganglion:
CTD Direct Evidence: marker/mechanism
CTD PMID:12151517, PMID:18234885, PMID:18774343, PMID:23006841, PMID:21958434 RGD:8657122 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18234883 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
G Vip vasoactive intestinal peptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:12787826 NCBI chr 1:42,169,307...42,177,582
Ensembl chr 1:42,169,501...42,177,582
JBrowse link
Hypoalgesia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp4 aquaporin 4 ISO RGD PMID:20851747 RGD:8696005 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Hdac4 histone deacetylase 4 ISO RGD PMID:19672313 RGD:9681457 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
INTELLECTUAL DEVELOPMENTAL DISORDER WITH GASTROINTESTINAL DIFFICULTIES AND HIGH PAIN THRESHOLD term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D ISO ClinVar Annotator: match by term: INTELLECTUAL DEVELOPMENTAL DISORDER WITH GASTROINTESTINAL DIFFICULTIES AND HIGH PAIN THRESHOLD
ClinVar Annotator: match by term: Intellectual developmental disorder with gastrointestinal difficulties and high pain threshold
ClinVar
OMIM
PMID:18265945, PMID:22065775, PMID:23242139, PMID:23907125, PMID:24262437, PMID:24267886, PMID:24911145, PMID:25356970, PMID:25741868, PMID:26823519, PMID:26847329, PMID:27479843, PMID:28135719, PMID:28343630, PMID:28852847, PMID:29752822, PMID:30216591, PMID:30388424 NCBI chr10:72,909,550...72,945,884
Ensembl chr10:72,909,550...72,945,884
JBrowse link
intermediate coronary syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO mRNA:increased expression:ventricular myocardium (human)
mRNA:increased expression:myocardium
RGD PMID:15131005, PMID:11451295 RGD:8142363, RGD:8548894 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Agt angiotensinogen ISO mRNA:increased expression:myocardium RGD PMID:11451295 RGD:8548894 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO mRNA:increased expression:myocardium RGD PMID:11451295 RGD:8548894 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO protein:increased serine phosphorylation:platelet RGD PMID:20467748 RGD:5509094 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Apoa4 apolipoprotein A4 ISO protein:decreased expression:blood plasma (human) RGD PMID:20367977 RGD:5685646 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Bdnf brain-derived neurotrophic factor ISO RGD PMID:16186425 RGD:4891111 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Crp C-reactive protein disease_progression ISO RGD PMID:9761079 RGD:9491780 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Edn1 endothelin 1 ISO associated with Coronary Artery Disease;protein:increased expression:coronary sinus, plasma (human) RGD PMID:14556009 RGD:8661755 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G F7 coagulation factor VII ISO protein:increased expression:plasma (human) RGD PMID:10653827 RGD:2312399 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:18333374 RGD:5508458 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Itga2 integrin subunit alpha 2 susceptibility ISO RGD PMID:15104219 RGD:1582303 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 ISO RGD PMID:10486281 RGD:1582334 NCBI chr16:6,970,367...6,985,538
Ensembl chr16:6,970,342...6,985,579
JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO RGD PMID:14675588 RGD:1582536 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Pappa1 pappalysin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11586954 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:2382605 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Selp selectin P ISO protein:increased expression:serum RGD PMID:21162967 RGD:6219003 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO RGD PMID:8122184 RGD:11035255 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:14592844 RGD:1580841 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Txn1 thioredoxin 1 ISO RGD PMID:15749180 RGD:1580784 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
Low Back Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:7888893 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Sparc secreted protein acidic and cysteine rich ISO CTD Direct Evidence: marker/mechanism CTD PMID:20714283 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
Microvascular Angina term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb1 bradykinin receptor B1 ISO mRNA:increased expression:blood, mononuclear cell RGD PMID:17852785 RGD:4890450 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO mRNA:increased expression:blood, mononuclear cell RGD PMID:17852785 RGD:4890450 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:transition:cds:g.677C>T (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:17491230, PMID:17491230 RGD:4891159 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO protein:decreased expression:serum RGD PMID:15648548 RGD:1620974 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
Musculoskeletal Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25218601 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25218601 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25218601 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
Myalgia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano5 anoctamin 5 ISO ClinVar Annotator: match by term: Muscle pain ClinVar PMID:9673985, PMID:20096397, PMID:21186264, PMID:21739273, PMID:21820307, PMID:22194990, PMID:22336395, PMID:22402862, PMID:22499103, PMID:22742934, PMID:22980763, PMID:23041008, PMID:23606453, PMID:23607914, PMID:24022920, PMID:24232312, PMID:24843231, PMID:25741868, PMID:25891276, PMID:26467025, PMID:27708273, PMID:28492532, PMID:30311386 NCBI chr 1:106,873,580...106,971,769
Ensembl chr 1:106,896,790...106,968,885
JBrowse link
G Capn3 calpain 3 ISO ClinVar Annotator: match by term: Muscle pain ClinVar PMID:7720071, PMID:9266733, PMID:10330340, PMID:10679950, PMID:14578192, PMID:14981715, PMID:15351423, PMID:15689361, PMID:15725583, PMID:16100770, PMID:16141003, PMID:16650086, PMID:17318636, PMID:20635405, PMID:21204801, PMID:21984748, PMID:25741868, PMID:26467025, PMID:27142102, PMID:28492532, PMID:30311386 NCBI chr 3:112,227,486...112,278,408
Ensembl chr 3:112,228,720...112,278,408
JBrowse link
G Clcn1 chloride voltage-gated channel 1 ISO ClinVar Annotator: match by term: Myalgia ClinVar PMID:30311386 NCBI chr 4:71,674,218...71,704,318
Ensembl chr 4:71,675,383...71,702,819
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III ISO ClinVar Annotator: match by term: Muscle pain ClinVar PMID:30311386 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 ISO ClinVar Annotator: match by term: Muscle pain ClinVar PMID:25741868, PMID:28492532, PMID:30311386 NCBI chr 4:6,559,153...6,799,888
Ensembl chr 4:6,559,545...6,799,632
JBrowse link
G Psmd6 proteasome 26S subunit, non-ATPase 6 ISO ClinVar Annotator: match by term: Myalgia ClinVar PMID:30311386 NCBI chr15:12,407,557...12,416,153
Ensembl chr15:12,407,524...12,416,105
JBrowse link
G Ryr1 ryanodine receptor 1 ISO ClinVar Annotator: match by term: Muscle pain ClinVar PMID:24195946, PMID:25741868, PMID:28259615, PMID:28492532, PMID:30311386 NCBI chr 1:87,959,596...88,066,252
Ensembl chr 1:87,959,712...88,066,101
JBrowse link
G Slc2a1 solute carrier family 2 member 1 ISO ClinVar Annotator: match by term: Muscle pain ClinVar PMID:25741868, PMID:30311386 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
Neck Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase severity ISO associated with breast cancer;DNA:missense mutation:cds:p.V158M (human) RGD PMID:21898113 RGD:8662332 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
Neuralgia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A IEP RGD PMID:12946573 RGD:6893571 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Adra2c adrenoceptor alpha 2C IEP RGD PMID:12946573 RGD:6893571 NCBI chr14:80,730,307...80,732,010
Ensembl chr14:80,730,307...80,732,010
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25014009 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17442347, PMID:18400411, PMID:19339603, PMID:24133248 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Cfl1 cofilin 1 treatment IEP associated with Sciatic Neuropathy RGD PMID:27216618 RGD:11568694 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Ctss cathepsin S IEP
IMP
RGD PMID:18700000, PMID:17551020 RGD:5686878, RGD:5686911 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Ctsz cathepsin Z IEP RGD PMID:18700000 RGD:5686878 NCBI chr 3:172,527,107...172,537,877
Ensembl chr 3:172,527,107...172,537,877
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31432094 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17292584 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17720801 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Drd1 dopamine receptor D1 IEP RGD PMID:22171983 RGD:6907447 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 IMP
IEP
RGD PMID:22902996, PMID:22171983 RGD:6907443, RGD:6907447 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Foxp3 forkhead box P3 treatment IEP
ISO
mRNA:increased expression: L4-L5 of the spinal cord RGD PMID:30858084, PMID:30858084 RGD:38599004, RGD:38599004 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Gal galanin and GMAP prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:18400411 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Gfra1 GDNF family receptor alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18400411 NCBI chr 1:279,203,046...279,572,789 JBrowse link
G Gja1 gap junction protein, alpha 1 ISO associated with Spinal Cord Injuries; RGD PMID:22951907 RGD:7364890 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Grk1 G protein-coupled receptor kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31432094 NCBI chr16:81,153,489...81,165,442
Ensembl chr16:81,153,489...81,165,442
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 treatment IEP RGD PMID:24216329 RGD:13792703 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Grm5 glutamate metabotropic receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19840219 NCBI chr 1:151,207,846...151,785,038
Ensembl chr 1:151,439,409...151,783,392
JBrowse link
G Hmgb1 high mobility group box 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25014009 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28011743 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Il10 interleukin 10 treatment IDA
IMP
ISO
RGD PMID:16949747, PMID:25078297, PMID:24077211 RGD:1598632, RGD:11049468, RGD:7364865 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12b interleukin 12B ISO CTD Direct Evidence: marker/mechanism CTD PMID:31432094 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Itgam integrin subunit alpha M IEP mRNA:increased expression:lumbar vertebra RGD PMID:15145554 RGD:1342461 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Kdr kinase insert domain receptor IEP RGD PMID:20705122 RGD:5684389 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Mir135a microRNA 135a ISO CTD Direct Evidence: marker/mechanism CTD PMID:31432094 NCBI chr 7:32,894,877...32,894,976
Ensembl chr 7:32,894,877...32,894,976
JBrowse link
G Mir135b microRNA 135b ISO CTD Direct Evidence: marker/mechanism CTD PMID:31432094 NCBI chr13:48,976,986...48,977,082
Ensembl chr13:48,976,986...48,977,082
JBrowse link
G Mir208a microRNA 208a ISO CTD Direct Evidence: marker/mechanism CTD PMID:31432094 NCBI chr15:33,613,451...33,613,533 JBrowse link
G Mir223 microRNA 223 treatment IDA RGD PMID:28580822 RGD:25824768 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Nos1 nitric oxide synthase 1 treatment IDA RGD PMID:23342771 RGD:7257658 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18400411 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373
JBrowse link
G Oprm1 opioid receptor, mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14718584, PMID:18400411 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
JBrowse link
G P2ry12 purinergic receptor P2Y12 IMP RGD PMID:20665560 RGD:6480524 NCBI chr 2:149,440,807...149,482,592
Ensembl chr 2:149,441,598...149,444,548
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30152261 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18400411 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Scn9a sodium voltage-gated channel alpha subunit 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19557861 NCBI chr 3:52,583,953...52,664,209
Ensembl chr 3:52,583,951...52,664,209
JBrowse link
G Tac1 tachykinin, precursor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18400411 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment IEP RGD PMID:24979268 RGD:11073677 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tlr4 toll-like receptor 4 IEP mRNA:increased expression:lumbar vertebra RGD PMID:15145554 RGD:1342461 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20846523 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfsf8 TNF superfamily member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31432094 NCBI chr 5:79,664,779...79,691,547
Ensembl chr 5:79,664,765...79,691,258
JBrowse link
Nociceptive Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grm8 glutamate metabotropic receptor 8 ISO RGD PMID:17113112 RGD:6771186 NCBI chr 4:54,474,344...55,409,526
Ensembl chr 4:54,474,136...55,407,922
JBrowse link
G Pomc proopiomelanocortin ISO RGD PMID:21380811 RGD:5508807 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:21371033 RGD:6483537 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
JBrowse link
G Vip vasoactive intestinal peptide IDA RGD PMID:19467283 RGD:5685608 NCBI chr 1:42,169,307...42,177,582
Ensembl chr 1:42,169,501...42,177,582
JBrowse link
Pain, Postoperative term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A ISO CTD Direct Evidence: therapeutic CTD PMID:20627697 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28434951 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Dusp6 dual specificity phosphatase 6 ISO associated with Inflammation RGD PMID:24155322 RGD:7771585 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
Pain, Referred term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor IMP RGD PMID:23313710 RGD:8655857 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
Painful Neuropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 ISO
IEP
protein:increased expression:medulla oblongata, dorsal horn of spinal cord (mouse)
protein:increased expression:ipsilateral side, dorsal root ganglion (rat)
RGD PMID:22721162, PMID:15041200 RGD:8548831, RGD:8548884 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ep300 E1A binding protein p300 treatment IMP
IEP
mRNA:increased expression:lumbar spinal cord (rat) RGD PMID:23176208, PMID:23176208 RGD:7327202, RGD:7327202 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Hmgb1 high mobility group box 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27474498 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Thbd thrombomodulin ISO CTD Direct Evidence: therapeutic CTD PMID:27474498 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Tlr4 toll-like receptor 4 treatment ISO RGD PMID:18615568 RGD:7815041 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor ISO
IMP
protein:increased expression:Schwann cell RGD PMID:11376190, PMID:10825476, PMID:9514564, PMID:18394803 RGD:7394735, RGD:7394741, RGD:7394740, RGD:7394739 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
paroxysmal extreme pain disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn9a sodium voltage-gated channel alpha subunit 9 ISO ClinVar Annotator: match by OMIM:167400
ClinVar Annotator: match by term: Paroxysmal extreme pain disorder
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: RECTAL PAIN, FAMILIAL
ClinVar
CTD
OMIM
PMID:15955112, PMID:17145499, PMID:17679678, PMID:18414213, PMID:18518989, PMID:18599537, PMID:19369487, PMID:19763161, PMID:21094958, PMID:21115638, PMID:21698661, PMID:21939494, PMID:22035805, PMID:22136189, PMID:22539570, PMID:22604722, PMID:22826602, PMID:22995991, PMID:23129781, PMID:23280954, PMID:23292638, PMID:23450472, PMID:23874707, PMID:23895530, PMID:24033266, PMID:24088041, PMID:24776970, PMID:24817410, PMID:24820863, PMID:24848745, PMID:25250524, PMID:25316021, PMID:25333069, PMID:25741868, PMID:25852444, PMID:25993546, PMID:26264438, PMID:26284228, PMID:26392352, PMID:26467025, PMID:26633545, PMID:26675522, PMID:26920677, PMID:27504264, PMID:27843123, PMID:27884173, PMID:27956748, PMID:28073787, PMID:28235406, PMID:28440294, PMID:28492532, PMID:29176367, PMID:29264398, PMID:29358611, PMID:29500686, PMID:29911575, PMID:30311386, PMID:30316835, PMID:30642272, PMID:30834459 NCBI chr 3:52,583,953...52,664,209
Ensembl chr 3:52,583,951...52,664,209
JBrowse link
Postherpetic Neuralgia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn8a sodium voltage-gated channel alpha subunit 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23382806 NCBI chr 7:142,575,629...142,683,659
Ensembl chr 7:142,575,672...142,684,114
JBrowse link
G Scn9a sodium voltage-gated channel alpha subunit 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23382806 NCBI chr 3:52,583,953...52,664,209
Ensembl chr 3:52,583,951...52,664,209
JBrowse link
Prinzmetal angina term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Icam1 intercellular adhesion molecule 1 ISO protein:increased expression:plasma RGD PMID:9415270 RGD:8547713 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 ISO RGD PMID:11984590 RGD:1581700 NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
Renal Colic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crp C-reactive protein ISO associated with Urolithiasis; RGD PMID:20206981 RGD:6909142 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
Sciatica term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bloc1s2 biogenesis of lysosomal organelles complex-1, subunit 2 IMP RGD PMID:16176350 RGD:2302154 NCBI chr 1:263,913,901...263,920,989
Ensembl chr 1:263,913,854...263,920,962
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B treatment IDA RGD PMID:22425187 RGD:7245944 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
Toothache term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npy1r neuropeptide Y receptor Y1 ISO CTD Direct Evidence: therapeutic CTD PMID:18809749 NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740
JBrowse link
Visceral Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A IMP RGD PMID:20047711 RGD:6480482 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Bdnf brain-derived neurotrophic factor ISO associated with Colitis; protein:increased expression:dorsal root ganglion: RGD PMID:21997550, PMID:19932037 RGD:8655978, RGD:8657331 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Penk proenkephalin treatment ISO RGD PMID:23316929 RGD:10003040 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IMP associated with Colitis; RGD PMID:23099257 RGD:10043788 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link
G Trpc4 transient receptor potential cation channel, subfamily C, member 4 IMP RGD PMID:24388923 RGD:13825245 NCBI chr 2:143,433,102...143,605,757
Ensembl chr 2:143,475,323...143,604,972
JBrowse link
G Trpc4Tn(sb-T2/Bart3)2.192Mcwi transient receptor potential cation channel, subfamily C, member 4; transposon insertion 2.192, Medical College of Wisconsin IMP RGD PMID:24388923 RGD:13825245

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16045
    Pathological Conditions, Signs and Symptoms 8735
      Signs and Symptoms 5235
        Neurologic Manifestations 4188
          Pain 319
            Abdominal Pain + 2
            Acute Pain 1
            Arthralgia + 6
            Back Pain + 3
            Breakthrough Pain 0
            Cancer Pain 3
            Chest Pain + 38
            Chronic Pain 8
            Earache 0
            Eye Pain 1
            Facial Pain + 1
            Flank Pain 0
            Glossalgia 0
            Headache + 15
            Hyperalgesia 193
            Hypoalgesia 2
            INTELLECTUAL DEVELOPMENTAL DISORDER WITH GASTROINTESTINAL DIFFICULTIES AND HIGH PAIN THRESHOLD 1
            Intractable Pain 0
            Labor Pain 0
            Levator Syndrome 0
            Mastodynia 0
            Metatarsalgia + 0
            Musculoskeletal Pain + 12
            Neck Pain 1
            Neuralgia + 47
            Nociceptive Pain + 14
            Pain, Postoperative + 5
            Pain, Referred 1
            Painful Neuropathy 6
            Pelvic Pain + 3
            Renal Colic 1
            familial episodic pain syndrome + 3
            paroxysmal extreme pain disorder 1
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.