ONTOLOGY REPORT - ANNOTATIONS


Term:Crush Syndrome
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Accession:DOID:9000921 term browser browse the term
Definition:Severe systemic manifestation of trauma and ischemia involving soft tissues, principally skeletal muscle, due to prolonged severe crushing. It leads to increased permeability of the cell membrane and to the release of potassium, enzymes, and myoglobin from within cells. Ischemic renal dysfunction secondary to hypotension and diminished renal perfusion results in acute tubular necrosis and uremia.
Synonyms:exact_synonym: Crush Syndromes
 primary_id: MESH:D003444;   RDO:0005298
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Crush Syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mb myoglobin JBrowse link 7 118,101,633 118,108,864 RGD:1582428

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Path 1
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  disease 14875
    syndrome 4220
      Crush Syndrome 1
Path 2
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  disease 14875
    Pathological Conditions, Signs and Symptoms 7362
      Pathologic Processes 4865
        Shock 324
          Shock, Traumatic 3
            Crush Syndrome 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.