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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Parakeratosis
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Accession:DOID:9000954 term browser browse the term
Definition:Persistence of the nuclei of the keratinocytes into the stratum corneum of the skin. This is a normal state only in the epithelium of true mucous membranes in the mouth and vagina. (Dorland, 27th ed)
Synonyms:exact_synonym: Parakeratoses
 narrow_synonym: Nasal parakeratosis
 primary_id: MESH:D010241;   RDO:0006278
 alt_id: OMIA:001373
For additional species annotation, visit the Alliance of Genome Resources.


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Parakeratosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Krt14 keratin 14 IEP RGD PMID:15809047 RGD:1600175 NCBI chr10:88,118,029...88,122,233
Ensembl chr10:88,055,823...88,122,233
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16023
    sensory system disease 5231
      skin disease 2765
        keratosis 187
          Parakeratosis 1
Path 2
Term Annotations click to browse term
  disease 16023
    disease of anatomical entity 15278
      nervous system disease 10897
        sensory system disease 5231
          skin disease 2765
            keratosis 187
              Parakeratosis 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.