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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Brain Injuries
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Accession:DOID:9000998 term browser browse the term
Definition:Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
Synonyms:exact_synonym: Acute Brain Injuries;   Acute Brain Injury;   Brain Injury;   Brain Laceration;   Brain Lacerations;   Focal Brain Injuries;   Focal Brain Injury
 primary_id: MESH:D001930;   RDO:0005055
For additional species annotation, visit the Alliance of Genome Resources.


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Brain Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 treatment IMP RGD PMID:21107131 RGD:12791995 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Acan aggrecan IEP mRNA:increased expression:fascia dentata (rat) RGD PMID:18511192 RGD:2315807 NCBI chr 1:140,762,758...140,824,441
Ensembl chr 1:140,762,758...140,824,441
JBrowse link
G Actr2 actin related protein 2 IEP mRNA, protein:decreased expression:hippocampus (rat) RGD PMID:22120305 RGD:11530046 NCBI chr14:104,338,486...104,375,840
Ensembl chr14:104,340,434...104,375,649
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 IDA RGD PMID:16689670 RGD:2325298 NCBI chr 9:121,705,897...121,725,736
Ensembl chr 9:121,706,979...121,725,716
JBrowse link
G Adra1a adrenoceptor alpha 1A IEP mRNA:increased expression:frontal cortex RGD PMID:20974230 RGD:5688366 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO
IEP
protein:increased expression:brain (rat) RGD PMID:22915134, PMID:24859607, PMID:22491548 RGD:7245513, RGD:8696001, RGD:7245557 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Aif1 allograft inflammatory factor 1 IEP protein:increased expression:cerebral cortex (rat) RGD PMID:19520144 RGD:2313020 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 IEP protein:increased expression:nucleus: RGD PMID:12091479 RGD:10053567 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Akt1 AKT serine/threonine kinase 1 IEP protein:increased phosphorylation:brain, neuron RGD PMID:16234845 RGD:5509090 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:7909931, PMID:17188501 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor ISO protein:increased expression:urine RGD PMID:14592616 RGD:6904155 NCBI chr 5:78,975,690...78,986,021
Ensembl chr 5:78,975,678...78,985,990
JBrowse link
G Ank3 ankyrin 3 IEP RGD PMID:20557305 RGD:6767288 NCBI chr20:19,948,767...20,480,628
Ensembl chr20:20,105,047...20,480,623
JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A IEP RGD PMID:24385964 RGD:10401136 NCBI chr 8:67,295,578...67,333,075
Ensembl chr 8:67,295,727...67,333,247
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 IEP protein:increased expression:cerebral cortex RGD PMID:11567033 RGD:2325751 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 IEP mRNA:increased expression:brain RGD PMID:12707777 RGD:2301208 NCBI chr 1:170,387,625...170,411,263
Ensembl chr 1:170,387,609...170,404,056
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11447995 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Apod apolipoprotein D IEP mRNA, protein:increased expression:cerebral cortex, glia cell, neuron RGD PMID:10501208 RGD:2311202 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
JBrowse link
G Apoe apolipoprotein E ISO GAD PMID:15118671 RGD:1331525 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G App amyloid beta precursor protein ISO protein:increased expression:hippocampus RGD PMID:16300758 RGD:10054281 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aqp4 aquaporin 4 IEP
ISO
protein:increased expression:cerebral cortex RGD PMID:21083433, PMID:21488209 RGD:5148014, RGD:5148034 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Asic1 acid sensing ion channel subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21307247 NCBI chr 7:141,324,714...141,354,937
Ensembl chr 7:141,326,321...141,354,937
JBrowse link
G Astn1 astrotactin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14499481 NCBI chr13:76,054,965...76,370,674
Ensembl chr13:76,055,410...76,370,674
JBrowse link
G Atg12 autophagy related 12 IEP protein:altered localization:brain RGD PMID:18059433 RGD:2301217 NCBI chr18:40,721,799...40,732,143
Ensembl chr18:40,721,800...40,732,126
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d treatment IDA RGD PMID:26813465 RGD:13800884 NCBI chr10:103,967,340...103,972,552
Ensembl chr10:103,967,312...103,972,668
JBrowse link
G Avpr1a arginine vasopressin receptor 1A IEP mRNA:increased expression:cerebral cortex RGD PMID:17244947 RGD:2300372 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Bad BCL2-associated agonist of cell death IEP mRNA, protein:increased expression:cerebral cortex RGD PMID:15941375 RGD:2292694 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:20888848 RGD:10054247 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 IEP Protein:increased expression:neurons RGD PMID:10686349 RGD:631308 NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IMP
IEP
RGD PMID:18093155, PMID:20888848 RGD:2293059, RGD:10054247 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor IEP
ISO
CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:15500971, PMID:21269288, PMID:20544832 RGD:4891136 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 IEP
ISO
protein:increased expression:neuron, astrocyte
protein:increased expression:hippocampus
protein:increased expression:brain
RGD PMID:18500386, PMID:24221859, PMID:16874043 RGD:6483098, RGD:11558018, RGD:6483314 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 IEP mRNA, protein:increased expression:brain, astrocyte, neuron RGD PMID:15453988 RGD:2293136 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bmp6 bone morphogenetic protein 6 IEP protein:increased expression:brain, astrocyte, neuron RGD PMID:16388909 RGD:2289020 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 IEP mRNA:increased expression:dentate gyrus, neuron RGD PMID:9080432 RGD:5129488 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Bysl bystin-like IEP mRNA, protein:increased expression:substantia nigra, striatum (rat) RGD PMID:15305856 RGD:2316201 NCBI chr 9:15,393,461...15,403,212
Ensembl chr 9:15,393,330...15,403,117
JBrowse link
G C1qa complement C1q A chain IEP RGD PMID:23808389 RGD:10054313 NCBI chr 5:155,261,254...155,264,101
Ensembl chr 5:155,261,250...155,264,143
JBrowse link
G C3 complement C3 IEP RGD PMID:23808389 RGD:10054313 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase IEP RGD PMID:25089700 RGD:11576302 NCBI chr  X:9,815,652...10,156,155
Ensembl chr  X:9,815,652...10,156,155
JBrowse link
G Casp1 caspase 1 IEP mRNA, protein:increased expression:brain RGD PMID:17188500 RGD:2315917 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 severity IEP mRNA, protein:increased expression, increased activity:cerebral cortex, hippocampus, neuron, astrocyte RGD PMID:14675152 RGD:2311485 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:20888848 RGD:10054247 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 IEP protein:altered localization RGD PMID:15590916 RGD:1624191 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cast calpastatin severity IEP mRNA:increased expression:cerebral cortex RGD PMID:15307896 RGD:5509821 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment IEP
ISO
IMP
protein:increased expression:brain, neuron
CTD Direct Evidence: marker/mechanism
CTD PMID:21549006, PMID:19210118, PMID:11113322 RGD:2306999, RGD:9587789 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 treatment IEP RGD PMID:22040257 RGD:7483630 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IEP mRNA:increased expression:hippocampus RGD PMID:24344922 RGD:8552265 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cd14 CD14 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd40 CD40 molecule treatment IDA RGD PMID:23924471 RGD:7248749 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand treatment IEP
IDA
RGD PMID:11755016, PMID:25972624 RGD:8547803, RGD:11344972 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A IEP protein:increased expression:nucleus: RGD PMID:9914434 RGD:8662346 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B IEP protein:decreased expression:cerebral cortex RGD PMID:21728064 RGD:10045359 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha ISO mRNA, protein:increased expression:cerebral cortex (mouse) RGD PMID:19833158 RGD:10401206 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta ISO mRNA, protein:increased expression:cerebral cortex (mouse)
CTD Direct Evidence: marker/mechanism
CTD PMID:21549006, PMID:19833158 RGD:10401206 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Ces1d carboxylesterase 1D ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cfb complement factor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17474994 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196
JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 treatment IEP RGD PMID:24252176 RGD:11565089 NCBI chr 3:113,318,559...113,324,459
Ensembl chr 3:113,318,563...113,324,461
JBrowse link
G Clec4e C-type lectin domain family 4, member E ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 4:156,271,087...156,276,243
Ensembl chr 4:156,270,920...156,276,304
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase IEP protein:increased expression:hippocampus RGD PMID:20215974 RGD:6483336 NCBI chr10:88,490,798...88,497,357
Ensembl chr10:88,490,798...88,497,356
JBrowse link
G Comt catechol-O-methyltransferase IEP protein:increased expression:hippocampus RGD PMID:17240060 RGD:2289740 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Crp C-reactive protein disease_progression ISO RGD PMID:24456846 RGD:9585646 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csf2 colony stimulating factor 2 disease_progression IDA RGD PMID:21515263 RGD:5686795 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006, PMID:24239694 RGD:11039431 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 IEP protein:altered expression:cerebral cortex RGD PMID:19473238 RGD:5686860 NCBI chr 8:61,532,465...61,567,510
Ensembl chr 8:61,532,465...61,567,510
JBrowse link
G Cul5 cullin 5 IEP mRNA, protein:decreased expression:cerebral cortex, hippocampus RGD PMID:17010517 RGD:2301432 NCBI chr 8:58,199,992...58,255,149
Ensembl chr 8:58,202,821...58,253,688
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP mRNA:increased expression:choroid plexus, cerebral cortex RGD PMID:19471279 RGD:5135009 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IEP protein:increased expression:brain, neuron RGD PMID:19210118 RGD:2306999 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP mRNA:increased expression:hindbrain RGD PMID:16329132 RGD:1599699 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 IEP RGD PMID:18847377 RGD:2301705 NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796
JBrowse link
G Dab2 DAB adaptor protein 2 IEP RGD PMID:15774263 RGD:7243841 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Dnmt1 DNA methyltransferase 1 IEP RGD PMID:19429151 RGD:9588608 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 IEP protein:increased degradation:cerebral cortex, hippocampus RGD PMID:17402852 RGD:2303056 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:18509630 RGD:2311580 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Dusp5 dual specificity phosphatase 5 IEP mRNA:increased expression:cerebral cortex RGD PMID:12503083 RGD:2317873 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha IDA RGD PMID:11526986 RGD:10395358 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eif3e eukaryotic translation initiation factor 3 subunit E treatment IMP RGD PMID:22960363 RGD:10395371 NCBI chr 7:82,997,694...83,037,231 JBrowse link
G Elk1 ETS transcription factor ELK1 IDA RGD PMID:15362724 RGD:7488910 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Epas1 endothelial PAS domain protein 1 treatment IDA RGD PMID:22960363 RGD:10395371 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Epha4 Eph receptor A4 ISO protein:increased expression, increased activity:astrocyte RGD PMID:22318127 RGD:5688763 NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:21075124 RGD:5688356 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Epo erythropoietin treatment ISO
IEP
CTD Direct Evidence: therapeutic
mRNA:increased expression:brain:
CTD PMID:20833152, PMID:23063952, PMID:18093155 RGD:10401061, RGD:2293059 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Epor erythropoietin receptor IEP mRNA:increased expression:brain: RGD PMID:18093155 RGD:2293059 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
JBrowse link
G F2 coagulation factor II severity ISO RGD PMID:21355766 RGD:5147766 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Fas Fas cell surface death receptor IEP
ISO
mRNA:increased expression:hippocampus
associated with Hyperoxia
RGD PMID:16078565, PMID:19107989 RGD:1600354, RGD:8662854 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:21269288 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fmr1 FMRP translational regulator 1 IEP protein:altered localization:hippocampus (rat) RGD PMID:16510718 RGD:11667962 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:9630518 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxp1 forkhead box P1 treatment IDA RGD PMID:26842647 RGD:11561903 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IEP protein:decreased expression:hippocampus RGD PMID:18501200 RGD:2307353 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 1:113,034,251...113,265,364
Ensembl chr 1:112,976,770...113,265,364
JBrowse link
G Gabrg3 gamma-aminobutyric acid type A receptor subunit gamma 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 1:112,158,525...112,812,267
Ensembl chr 1:112,158,519...112,811,936
JBrowse link
G Gdnf glial cell derived neurotrophic factor IEP mRNA:increased expression:brain RGD PMID:18501516 RGD:2324932 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gja1 gap junction protein, alpha 1 treatment IEP RGD PMID:23485053 RGD:8662424 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gja5 gap junction protein, alpha 5 IEP protein:increased expression:cerebral artery RGD PMID:21895483 RGD:7207391 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Gpx1 glutathione peroxidase 1 IEP mRNA:decreased expression:hippocampus, neuron RGD PMID:15791111 RGD:2306624 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Grm8 glutamate metabotropic receptor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 4:54,474,344...55,409,526
Ensembl chr 4:54,474,136...55,407,922
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:24675465, PMID:22643085 RGD:10045646 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsn gelsolin IEP RGD PMID:14588109 RGD:1599864 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IEP mRNA,protein:decreased expression:hippocampus: RGD PMID:11726545 RGD:9686434 NCBI chr 2:50,099,576...50,499,799
Ensembl chr 2:50,099,576...50,499,799
JBrowse link
G Hmgb1 high mobility group box 1 treatment IMP RGD PMID:22915134 RGD:7245513 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:18562561 RGD:5508455 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 IEP RGD PMID:23470432 RGD:10755702 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hp haptoglobin IEP mRNA:increased expression:liver RGD PMID:23172820 RGD:11041806 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism
CTD PMID:21549006, PMID:21549006 RGD:5147593 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 IEP protein:increased expression:cerebral white matter (rat) RGD PMID:22067617 RGD:5688785 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IEP RGD PMID:11746764 RGD:6480530 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IMP RGD PMID:22465320 RGD:6482178 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP protein:increased expression:brain: RGD PMID:16230799 RGD:11522716 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifnl3 interferon, lambda 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 1:85,236,243...85,237,775
Ensembl chr 1:85,236,243...85,237,775
JBrowse link
G Igf1 insulin-like growth factor 1 treatment ISO human protein in a rat model RGD PMID:9344566 RGD:12904928 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf2 insulin-like growth factor 2 IEP mRNA:decreased expression:brain RGD PMID:11123717 RGD:5509972 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Il10 interleukin 10 severity
treatment
ISO
IDA
CTD Direct Evidence: marker/mechanism CTD PMID:21549006, PMID:23075771, PMID:23971414 RGD:7364822, RGD:7364983 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 4:98,049,195...98,141,562
Ensembl chr 4:98,052,842...98,141,482
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr  X:118,443,955...118,514,716
Ensembl chr  X:118,443,823...118,513,061
JBrowse link
G Il16 interleukin 16 IEP RGD PMID:17983426 RGD:5024939 NCBI chr 1:145,781,923...145,881,538
Ensembl chr 1:145,781,928...145,870,912
JBrowse link
G Il17rd interleukin 17 receptor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr16:2,670,471...2,737,271
Ensembl chr16:2,670,618...2,731,808
JBrowse link
G Il18 interleukin 18 severity IMP
ISO
mRNA, protein:increased expression:brain RGD PMID:17188500, PMID:17188500 RGD:2315917, RGD:2315917 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il18r1 interleukin 18 receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 9:47,184,404...47,217,403
Ensembl chr 9:47,185,443...47,219,175
JBrowse link
G Il1a interleukin 1 alpha IEP
ISO
mRNA, protein:increased expression:cerebral cortex
CTD Direct Evidence: marker/mechanism
CTD PMID:21549006, PMID:16024175 RGD:2311098 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta IEP
ISO
mRNA, protein:increased expression:cerebral cortex
CTD Direct Evidence: marker/mechanism
protein:increased expression:brain, cerebrospinal fluid
mRNA, protein:increased expression:brain
CTD PMID:19800810, PMID:21549006, PMID:16024175, PMID:22503903, PMID:17612572 RGD:2311098, RGD:6482651, RGD:1626652 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r1 interleukin 1 receptor type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO CTD Direct Evidence: therapeutic CTD PMID:25665855 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il2 interleukin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il3 interleukin 3 disease_progression IDA
ISO
protein: increased expression: brain: microdialysis perfusate RGD PMID:21515263, PMID:20717122 RGD:5686795, RGD:5686886 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il31ra interleukin 31 receptor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 2:44,333,347...44,408,005
Ensembl chr 2:44,336,006...44,394,709
JBrowse link
G Il4 interleukin 4 IEP protein:decreased expression:plasma RGD PMID:24519543 RGD:10402802 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 treatment IEP RGD PMID:24602693, PMID:24530657 RGD:11522766, RGD:11522770 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 IEP
ISO
protein:increased expression:cerebrospinal fluid (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:19800810, PMID:21549006, PMID:23159883, PMID:10027774 RGD:11049549 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il7 interleukin 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977
JBrowse link
G Il9r interleukin 9 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr10:15,697,216...15,708,684
Ensembl chr10:15,696,824...15,710,423
JBrowse link
G Irf1 interferon regulatory factor 1 IEP
ISO
mRNA:increased expression:cerebral cortex
CTD Direct Evidence: marker/mechanism
CTD PMID:21549006, PMID:12503083 RGD:2317873 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Jak2 Janus kinase 2 IMP RGD PMID:21596098 RGD:6483023 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 IEP RGD PMID:20861444 RGD:8662901 NCBI chr13:90,722,945...90,753,338
Ensembl chr13:90,723,092...90,752,581
JBrowse link
G Kdr kinase insert domain receptor IEP
IMP
protein:increased expression:cerebral cortex RGD PMID:21307798, PMID:19733172 RGD:5684382, RGD:5684402 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Lep leptin IEP RGD PMID:21276361 RGD:5128517 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lsg1 large 60S subunit nuclear export GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14499481 NCBI chr11:73,693,862...73,723,457
Ensembl chr11:73,693,814...73,723,501
JBrowse link
G Ly86 lymphocyte antigen 86 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr17:28,104,535...28,191,447
Ensembl chr17:28,104,589...28,191,436
JBrowse link
G Mag myelin-associated glycoprotein susceptibility IMP RGD PMID:17156367 RGD:9685230 NCBI chr 1:89,345,325...89,360,905
Ensembl chr 1:89,345,429...89,360,733
JBrowse link
G Map1b microtubule-associated protein 1B IEP protein:increased expression, increased phosphorylation:brain RGD PMID:10906717 RGD:2304029 NCBI chr 2:29,675,391...29,768,750
Ensembl chr 2:29,675,391...29,768,750
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha IEP RGD PMID:24221859 RGD:11558018 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Map2 microtubule-associated protein 2 IEP
IDA
protein:decreased expression:cerebral cortex, neuron RGD PMID:21401443, PMID:20568963 RGD:6483087, RGD:6483089 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Mbl2 mannose binding lectin 2 disease_progression ISO RGD PMID:18183030 RGD:12910935 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Mbp myelin basic protein IDA RGD PMID:18583256 RGD:7349333 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Mdm2 MDM2 proto-oncogene IEP protein:increased expression:brain cortex (rat) RGD PMID:15165363 RGD:2317397 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mif macrophage migration inhibitory factor IEP RGD PMID:15922484 RGD:1641989 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mir132 microRNA 132 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr10:62,014,995...62,015,095
Ensembl chr10:62,014,995...62,015,095
JBrowse link
G Mir144 microRNA 144 IEP RGD PMID:25089700 RGD:11576302 NCBI chr10:65,291,365...65,291,447
Ensembl chr10:65,291,365...65,291,447
JBrowse link
G Mir153 microRNA 153 IEP RGD PMID:25089700 RGD:11576302 NCBI chr 6:145,105,064...145,105,150
Ensembl chr 6:145,105,064...145,105,150
JBrowse link
G Mir183 microRNA 183 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 4:57,463,569...57,463,678
Ensembl chr 4:57,463,569...57,463,678
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment IDA
IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:19631748, PMID:16671440, PMID:24661104 RGD:1582656, RGD:13207312 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II IEP mRNA, protein:increased expression:hippocampus RGD PMID:11686499 RGD:2302298 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt2A metallothionein 2A ISO
IEP
mRNA:increased expression:liver (mouse)
mRNA:increased expression:dentate gyrus (rat)
RGD PMID:22363575, PMID:15650329 RGD:6483812, RGD:6483847 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mt3 metallothionein 3 treatment IDA
IEP
RGD PMID:16314047, PMID:10595827, PMID:10218634 RGD:6480628, RGD:9685805, RGD:9685803 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Myoc myocilin IEP mRNA:increased expression:cerebral cortex (rat) RGD PMID:12799138 RGD:7401267 NCBI chr13:80,517,531...80,527,928
Ensembl chr13:80,517,536...80,527,928
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 IEP protein:increased expression:lung: RGD PMID:18787991, PMID:25089700 RGD:5134971, RGD:11576302 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Ngb neuroglobin severity IEP RGD PMID:21915648 RGD:9743963 NCBI chr 6:111,126,259...111,131,699
Ensembl chr 6:111,126,261...111,132,320
JBrowse link
G Ngfr nerve growth factor receptor treatment IDA RGD PMID:23940017 RGD:10414074 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nos2 nitric oxide synthase 2 IEP RGD PMID:11526986 RGD:10395358 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nppb natriuretic peptide B ISO associated with lung diseases;protein:increased expression:serum:
CTD Direct Evidence: therapeutic
CTD PMID:19803787, PMID:23837838 RGD:7247620 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Npy neuropeptide Y IEP protein:increased expression:adrenal medulla RGD PMID:23570732 RGD:10448961 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP mRNA:increased expression:lung
associated with Subarachnoid Hemorrhage
RGD PMID:18787991, PMID:20864352 RGD:5134971, RGD:11035222 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nt5e 5' nucleotidase, ecto IEP protein:altered expression:cerebral cortex (rat) RGD PMID:21337375 RGD:5134348 NCBI chr 8:95,969,002...96,012,733
Ensembl chr 8:95,968,652...96,012,696
JBrowse link
G P2ry1 purinergic receptor P2Y1 IEP protein:increased expression:brain, astrocyte RGD PMID:19115395 RGD:2315811 NCBI chr 2:151,314,818...151,320,312
Ensembl chr 2:151,314,818...151,320,319
JBrowse link
G Palld palladin, cytoskeletal associated protein IEP protein:increased expression:brain, astrocyte RGD PMID:12932445 RGD:2325786 NCBI chr16:31,865,712...31,948,168 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17640816 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pawr pro-apoptotic WT1 regulator IEP mRNA,protein:increased expression:brain: RGD PMID:11421591 RGD:9835358 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068
JBrowse link
G Pde4d phosphodiesterase 4D IEP mRNA, protein:alternative form, decreased phosphorylation:brain RGD PMID:23057870 RGD:7327147 NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264
JBrowse link
G Pdgfa platelet derived growth factor subunit A IEP mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdgfb platelet derived growth factor subunit B IEP mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEP mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IEP mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IDA RGD PMID:22658532 RGD:6484732 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pglyrp1 peptidoglycan recognition protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 1:79,790,879...79,796,064
Ensembl chr 1:79,790,705...79,796,111
JBrowse link
G Pgr progesterone receptor IEP RGD PMID:23211561 RGD:7248711 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Phb prohibitin IEP protein:increased oxidation:cerebral cortex RGD PMID:17518533 RGD:2292409 NCBI chr10:83,476,107...83,488,878
Ensembl chr10:83,476,107...83,488,878
JBrowse link
G Phb2 prohibitin 2 IEP RGD PMID:24566151 RGD:12903261 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367
JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 IEP protein:decreased expression:brain, nucleus RGD PMID:21545521 RGD:8693413 NCBI chr 8:67,771,720...67,869,015
Ensembl chr 8:67,771,720...67,869,019
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IDA agonist more effective in combination with simvastatin RGD PMID:18562561 RGD:5508455 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha treatment ISO
IEP
protein:decreased expression:frontal cortex (rat) RGD PMID:22642418, PMID:24345766 RGD:6484257, RGD:10059630 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha IEP
ISO
protein: :hippocampus
CTD Direct Evidence: marker/mechanism
CTD PMID:14499481, PMID:19751097 RGD:6483311 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Prf1 perforin 1 ISO RGD PMID:20537642 RGD:6482807 NCBI chr20:30,915,294...30,920,804
Ensembl chr20:30,915,213...30,921,382
JBrowse link
G Ptger3 prostaglandin E receptor 3 IEP protein:increased expression:striatum, microglia (rat) RGD PMID:15234107 RGD:9850280 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO
IEP
protein:increased expression:microglia, macrophage
protein:increased expression:microglial cells, macrophage, endothelial cell
RGD PMID:19719848, PMID:11565600, PMID:12005397 RGD:5688162, RGD:5688242, RGD:5688239 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:12410334, PMID:20810888, PMID:21549006, PMID:21866634, PMID:19719848 RGD:5508191, RGD:5688162 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 IEP RGD PMID:12088737 RGD:727637 NCBI chr 4:49,941,046...50,140,764
Ensembl chr 4:49,941,304...50,140,762
JBrowse link
G Rchy1 ring finger and CHY zinc finger domain containing 1 IEP protein:increased expression:cerebral cortex RGD PMID:21728064 RGD:10045359 NCBI chr14:17,615,968...17,631,715
Ensembl chr14:17,615,968...17,631,714
JBrowse link
G Reg3b regenerating family member 3 beta IEP mRNA:increased expression:cerebral cortex (rat) RGD PMID:19351265 RGD:9831399 NCBI chr 4:109,467,272...109,470,510
Ensembl chr 4:109,467,272...109,470,510
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEP protein:increased expression:ileum RGD PMID:18288455 RGD:2298787 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ret ret proto-oncogene IEP mRNA:increased expression:brain RGD PMID:18501516 RGD:2324932 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G Rhoa ras homolog family member A IEP protein:increased expression:microglial cell, brain RGD PMID:17929039 RGD:2298888 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Robo1 roundabout guidance receptor 1 IEP mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317
JBrowse link
G Robo2 roundabout guidance receptor 2 IEP mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr11:11,062,866...12,618,793
Ensembl chr11:11,062,790...11,585,765
JBrowse link
G Robo3 roundabout guidance receptor 3 IEP mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr 8:39,892,792...39,923,735
Ensembl chr 8:39,892,792...39,907,478
JBrowse link
G Rps27a ribosomal protein S27a IEP mRNA:decreased expression:cerebral cortex, hippocampus RGD PMID:17936732 RGD:11041870 NCBI chr14:113,966,163...113,968,440
Ensembl chr14:113,966,611...113,968,268
Ensembl chr 5:113,966,611...113,968,268
JBrowse link
G S100b S100 calcium binding protein B severity ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:11520488, PMID:21783483, PMID:21976236 RGD:5508761 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Sele selectin E IEP protein:increased expression:brain RGD PMID:19107536 RGD:2313599 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Serpinc1 serpin family C member 1 ISO CTD Direct Evidence: therapeutic CTD PMID:21534203 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Serpinf1 serpin family F member 1 treatment ISO
IEP
human gene in a rat model
protein:altered expression:cerebellum (rat)
RGD PMID:20142768, PMID:17709187 RGD:8612994, RGD:8622925 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
G Sirt1 sirtuin 1 treatment IEP RGD PMID:17970622 RGD:9497541 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Skp2 S-phase kinase associated protein 2 IEP protein:increased expression:brain RGD PMID:19852587 RGD:2315049 NCBI chr 2:58,506,146...58,534,211
Ensembl chr 2:58,506,151...58,534,211
JBrowse link
G Slc18a3 solute carrier family 18 member A3 IEP protein:decreased expression:brain RGD PMID:18848922 RGD:5686682 NCBI chr16:8,682,668...8,685,529
Ensembl chr16:8,682,669...8,685,529
JBrowse link
G Slit1 slit guidance ligand 1 IEP mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr 1:260,843,481...260,992,366
Ensembl chr 1:260,843,483...260,992,366
JBrowse link
G Slit3 slit guidance ligand 3 IEP mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr10:19,924,200...20,517,918
Ensembl chr10:20,320,878...20,518,518
JBrowse link
G Snca synuclein alpha ISO
IEP
RGD PMID:14637093, PMID:25089700 RGD:6480195, RGD:11576302 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sncb synuclein, beta ISO RGD PMID:14637093 RGD:6480195 NCBI chr17:10,384,472...10,392,776
Ensembl chr17:10,384,511...10,392,843
JBrowse link
G Sncg synuclein, gamma ISO RGD PMID:14637093 RGD:6480195 NCBI chr16:10,722,110...10,726,648
Ensembl chr16:10,722,106...10,726,707
JBrowse link
G Snw1 SNW domain containing 1 IEP mRNA, protein:increased expression:cerebral cortex (rat) RGD PMID:22965216 RGD:11035237 NCBI chr 6:111,483,698...111,507,782
Ensembl chr 6:111,483,703...111,507,782
JBrowse link
G Sod1 superoxide dismutase 1 ISO RGD PMID:16248885 RGD:1581214 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:24462953, PMID:16248885 RGD:1581214 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sparc secreted protein acidic and cysteine rich IEP mRNA:increased expression:brain, blood vessel RGD PMID:9704602 RGD:2300066 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Sstr2 somatostatin receptor 2 IEP RGD PMID:11879809 RGD:2325002 NCBI chr10:102,136,283...102,143,449
Ensembl chr10:102,136,283...102,143,434
JBrowse link
G Sstr3 somatostatin receptor 3 IEP RGD PMID:11879809 RGD:2325002 NCBI chr 7:119,760,881...119,768,082
Ensembl chr 7:119,760,888...119,768,082
JBrowse link
G Sstr4 somatostatin receptor 4 IEP RGD PMID:11879809 RGD:2325002 NCBI chr 3:142,739,781...142,741,644
Ensembl chr 3:142,739,781...142,741,644
JBrowse link
G Stat1 signal transducer and activator of transcription 1 IMP RGD PMID:21596098 RGD:6483023 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat3 signal transducer and activator of transcription 3 IMP
IDA
protein:increased phosphorylation:brain RGD PMID:21596098, PMID:22145815, PMID:22827467 RGD:6483023, RGD:8694312, RGD:6892706 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Strn striatin IEP RGD PMID:16351572 RGD:2311293 NCBI chr 6:1,232,729...1,319,603
Ensembl chr 6:1,237,758...1,319,541
JBrowse link
G Tardbp TAR DNA binding protein ISO RGD PMID:22101322 RGD:5687195 NCBI chr 5:165,432,089...165,442,232
Ensembl chr 5:165,432,095...165,442,048
JBrowse link
G Tf transferrin IEP RGD PMID:22538758 RGD:7244386 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Th tyrosine hydroxylase IEP protein:decreased activity:striatum (rat) RGD PMID:21047500 RGD:5128822 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Thbd thrombomodulin onset ISO RGD PMID:17895610 RGD:5685007 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Ticam2 toll-like receptor adaptor molecule 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr18:40,555,106...40,572,569
Ensembl chr18:40,555,106...40,572,241
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 IEP mRNA:increased expression:brain, astrocytes RGD PMID:10719361 RGD:2290468 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 IEP mRNA:increased expression:brain, neuron, microglial cell RGD PMID:10719361 RGD:2290468 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tjp1 tight junction protein 1 IEP RGD PMID:19889224 RGD:2325128 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tlr1 toll-like receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr14:45,062,662...45,065,014
Ensembl chr14:45,062,662...45,081,991
JBrowse link
G Tlr2 toll-like receptor 2 IEP
ISO
mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism
CTD PMID:21549006, PMID:18316784 RGD:2312713 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 IEP
ISO
mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism
CTD PMID:21549006, PMID:18316784 RGD:2312713 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tlr9 toll-like receptor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
JBrowse link
G Tnf tumor necrosis factor ISO
IMP
CTD Direct Evidence: marker/mechanism CTD PMID:19800810, PMID:21549006, PMID:10674461 RGD:13825262 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf13b TNF receptor superfamily member 13B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr10:47,399,834...47,422,907
Ensembl chr10:47,412,582...47,420,951
JBrowse link
G Tnfrsf13c TNF receptor superfamily member 13C ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 7:123,453,799...123,456,289
Ensembl chr 7:123,453,788...123,456,268
JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 5:172,328,259...172,337,221
Ensembl chr 5:172,328,262...172,335,892
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEP
ISO
protein:increased expression:brain
CTD Direct Evidence: marker/mechanism
CTD PMID:21549006, PMID:17074049 RGD:1624183 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tnfsf12 TNF superfamily member 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr10:56,290,780...56,300,137
Ensembl chr10:56,290,780...56,300,077
JBrowse link
G Traf4 Tnf receptor associated factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr10:65,418,688...65,424,802
Ensembl chr10:65,418,700...65,424,802
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 IEP mRNA, protein:increased expression:cerebral cortex, hippocampus RGD PMID:20309649 RGD:9999437 NCBI chr20:11,434,062...11,482,880
Ensembl chr20:11,436,267...11,482,051
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 IEP mRNA:decreased expression:cerebral cortex, hippocampus (rat) RGD PMID:17936732 RGD:11041870 NCBI chr16:20,668,925...20,671,127
Ensembl chr16:20,668,971...20,671,127
JBrowse link
G Ucp2 uncoupling protein 2 ISO CTD Direct Evidence: therapeutic CTD PMID:12858170, PMID:12858170 RGD:7204436 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Vegfa vascular endothelial growth factor A IEP
ISO
CTD Direct Evidence: therapeutic CTD PMID:18065154, PMID:12230324 RGD:1580574 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vegfb vascular endothelial growth factor B IEP mRNA, protein:increased expression:brain RGD PMID:12230324 RGD:1580574 NCBI chr 1:222,237,000...222,242,786
Ensembl chr 1:222,239,022...222,242,644
JBrowse link
G Vim vimentin ISO
IEP
protein:increased expression:brain RGD PMID:19728994, PMID:15527750 RGD:6480519, RGD:6480527 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Xdh xanthine dehydrogenase treatment IEP RGD PMID:26528358 RGD:13208950 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
brain compression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 treatment ISO RGD PMID:25708984 RGD:12738361 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
Brain Concussion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 IEP RGD PMID:26448536 RGD:13506960 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 IEP RGD PMID:26448536 RGD:13506960 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Drd4 dopamine receptor D4 IEP RGD PMID:26448536 RGD:13506960 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Il6 interleukin 6 treatment IDA RGD PMID:27113205 RGD:11062140 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
Brain Contusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 treatment IEP RGD PMID:28140659 RGD:13782305 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 treatment IEP RGD PMID:28140659 RGD:13782305 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
Brain Injuries, Diffuse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G S100b S100 calcium binding protein B ISO CTD Direct Evidence: marker/mechanism CTD PMID:30076900 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
Brain Injuries, Traumatic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 ADAM metallopeptidase domain 10 IEP RGD PMID:22489706 RGD:13703033 NCBI chr 8:77,107,355...77,237,483
Ensembl chr 8:77,107,536...77,237,483
JBrowse link
G App amyloid beta precursor protein treatment ISO RGD PMID:29320530 RGD:13782048 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Bad BCL2-associated agonist of cell death treatment IEP RGD PMID:24582457 RGD:13782254 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Capn1 calpain 1 IEP protein:increased expression:cytosol, plasma membrane RGD PMID:9469158 RGD:13792664 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
JBrowse link
G Capn2 calpain 2 IEP RGD PMID:9469158 RGD:13792664 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 treatment ISO RGD PMID:26435412 RGD:27095897 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Drd1 dopamine receptor D1 treatment IEP RGD PMID:24047867 RGD:13506948 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 treatment IEP RGD PMID:24047867 RGD:13506948 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Fubp1 far upstream element binding protein 1 IEP RGD PMID:23797733 RGD:13673879 NCBI chr 2:257,425,676...257,452,745
Ensembl chr 2:257,425,679...257,449,568
JBrowse link
G Gnal G protein subunit alpha L IEP RGD PMID:29215295 RGD:13513923 NCBI chr18:62,805,406...62,946,133
Ensembl chr18:62,805,410...62,944,630
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Itgb1 integrin subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Lama1 laminin subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr 9:115,916,907...116,042,123
Ensembl chr 9:115,916,907...116,042,123
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 IEP protein:increased expression:hippocampus: RGD PMID:28365875 RGD:13703062 NCBI chr  X:124,722,628...124,766,079
Ensembl chr  X:124,722,628...124,766,044
JBrowse link
G Mapt microtubule-associated protein tau treatment IDA
IEP
RGD PMID:28412141, PMID:25771151, PMID:26484783, PMID:26729399 RGD:13800902, RGD:13800917, RGD:13800912, RGD:13800909 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mir155 microRNA 155 ISO RGD PMID:28804446 RGD:25314324 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Ncstn nicastrin ISO RGD PMID:18240300 RGD:13801189 NCBI chr13:90,451,046...90,467,256
Ensembl chr13:90,451,044...90,467,256
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 IEP protein:increased expression:brain: RGD PMID:30855558 RGD:26884463 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:27822499 NCBI chr 5:166,409,460...166,430,291
Ensembl chr 5:166,409,461...166,430,254
JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ocln occludin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829224, PMID:28642177 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pde10a phosphodiesterase 10A IEP RGD PMID:29215295 RGD:13513923 NCBI chr 1:52,360,296...52,544,448
Ensembl chr 1:52,360,296...52,544,450
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha IEP RGD PMID:20713027 RGD:13830881 NCBI chr14:100,311,224...100,360,879
Ensembl chr14:100,311,173...100,360,879
JBrowse link
G Ppp3r2 protein phosphatase 3, regulatory subunit B, beta IEP RGD PMID:20713027 RGD:13830881 NCBI chr 5:64,945,583...64,946,578
Ensembl chr 5:64,945,583...64,946,580
JBrowse link
G Psen1 presenilin 1 ISO RGD PMID:18240300 RGD:13801189 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593, PMID:28642177 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment IEP RGD PMID:28433746 RGD:14995478 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 treatment IMP RGD PMID:27553877 RGD:14995939 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Ube4b ubiquitination factor E4B ISO CTD Direct Evidence: therapeutic CTD PMID:27822499 NCBI chr 5:166,156,033...166,259,069
Ensembl chr 5:166,156,033...166,259,069
JBrowse link
Chronic Brain Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E susceptibility ISO DNA:polymorphism:exon: RGD PMID:9214529 RGD:7495763 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Tardbp TAR DNA binding protein ISO protein:increased expression:brain RGD PMID:20720505 RGD:5687179 NCBI chr 5:165,432,089...165,442,232
Ensembl chr 5:165,432,095...165,442,048
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16023
    Wounds and Injuries 835
      Nervous System Trauma 531
        Craniocerebral Trauma 336
          Brain Injuries 271
            Brain Injuries, Diffuse + 1
            Brain Injuries, Traumatic + 40
            Chronic Brain Injury + 2
            Epilepsy, Post-Traumatic 0
            Pneumocephalus 0
            Shaken Baby Syndrome 0
            brain compression 1
Path 2
Term Annotations click to browse term
  disease 16023
    disease of anatomical entity 15278
      nervous system disease 10897
        Nervous System Trauma 531
          Craniocerebral Trauma 336
            Brain Injuries 271
              Brain Injuries, Diffuse + 1
              Brain Injuries, Traumatic + 40
              Chronic Brain Injury + 2
              Epilepsy, Post-Traumatic 0
              Pneumocephalus 0
              Shaken Baby Syndrome 0
              brain compression 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.