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ONTOLOGY REPORT - ANNOTATIONS


Term:Multiple Primary Neoplasms
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Accession:DOID:9001030 term browser browse the term
Definition:Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.
Synonyms:exact_synonym: Synchronous Multiple Primary Neoplasms;   Synchronous Neoplasm;   multiple primary neoplasm;   synchronous neoplasms
 primary_id: MESH:D009378
 alt_id: RDO:0005711
For additional species annotation, visit the Alliance of Genome Resources.


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Multiple Primary Neoplasms term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnmt3b DNA methyltransferase 3 beta JBrowse link NW_004955422 28,380,595 28,427,012 RGD:9068941
G Mlh1 mutL homolog 1 JBrowse link NW_004955421 3,890,291 3,936,892 RGD:9068941
Bannayan-Riley-Ruvalcaba syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link NW_004955420 8,355,415 8,427,024 RGD:9068941
G Pten phosphatase and tensin homolog JBrowse link NW_004955425 5,007,811 5,091,829 RGD:9068941
Cowden syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Egfr epidermal growth factor receptor JBrowse link NW_004955456 321,222 456,431 RGD:9068941
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link NW_004955420 8,355,415 8,427,024 RGD:9068941
G Pten phosphatase and tensin homolog JBrowse link NW_004955425 5,007,811 5,091,829 RGD:7240710
G Rint1 RAD50 interactor 1 JBrowse link NW_004955410 10,121,322 10,144,748 RGD:9068941
G Sdhb succinate dehydrogenase complex iron sulfur subunit B JBrowse link NW_004955527 1,769,280 1,792,496 RGD:9068941
Cowden Syndrome 5 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link NW_004955420 8,355,415 8,427,024 RGD:7240710
Cowden Syndrome 6 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link NW_004955538 3,208,711 3,224,386 RGD:7240710
Cowden Syndrome 7 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sec23b SEC23 homolog B, COPII coat complex component JBrowse link NW_004955415 27,044,694 27,075,028 RGD:7240710
Cowden-Like Syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link NW_004955420 8,355,415 8,427,024 RGD:9068941
G Pten phosphatase and tensin homolog JBrowse link NW_004955425 5,007,811 5,091,829 RGD:9068941
familial medullary thyroid carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Insrr insulin receptor related receptor JBrowse link NW_004955545 2,911,691 2,928,335 RGD:9068941
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link NW_004955545 2,929,704 2,947,579 RGD:9068941
G Ret ret proto-oncogene JBrowse link NW_004955546 1,221,995 1,252,147 RGD:7240710
Macrocephaly Mesodermal Hamartoma Spectrum term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link NW_004955538 3,208,711 3,224,386 RGD:9068941
multiple endocrine neoplasia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdkn1b cyclin dependent kinase inhibitor 1B JBrowse link NW_004955413 9,615,542 9,620,542 RGD:9068941
G Ghrl ghrelin and obestatin prepropeptide JBrowse link NW_004955561 1,676,475 1,682,205 RGD:9068941
G Ghsr growth hormone secretagogue receptor JBrowse link NW_004955420 2,483,173 2,486,414 RGD:9068941
G Gpr19 G protein-coupled receptor 19 JBrowse link NW_004955413 9,551,156 9,596,279 RGD:9068941
G Men1 menin 1 JBrowse link NW_004955422 20,356,491 20,363,374 RGD:9068941
G Ret ret proto-oncogene JBrowse link NW_004955546 1,221,995 1,252,147 RGD:9068941
multiple endocrine neoplasia type 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf2 fibroblast growth factor 2 JBrowse link NW_004955428 17,840,554 17,894,779 RGD:9068941
G Men1 menin 1 JBrowse link NW_004955422 20,356,491 20,363,374 RGD:7240710
RGD:9068941
G Ret ret proto-oncogene JBrowse link NW_004955546 1,221,995 1,252,147 RGD:9068941
multiple endocrine neoplasia type 2A term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ret ret proto-oncogene JBrowse link NW_004955546 1,221,995 1,252,147 RGD:7240710
multiple endocrine neoplasia type 2B term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ret ret proto-oncogene JBrowse link NW_004955546 1,221,995 1,252,147 RGD:7240710
multiple endocrine neoplasia type 4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdkn1b cyclin dependent kinase inhibitor 1B JBrowse link NW_004955413 9,615,542 9,620,542 RGD:7240710
G Gpr19 G protein-coupled receptor 19 JBrowse link NW_004955413 9,551,156 9,596,279 RGD:9068941
G Ret ret proto-oncogene JBrowse link NW_004955546 1,221,995 1,252,147 RGD:9068941
Proteus syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link NW_004955538 3,208,711 3,224,386 RGD:7240710
G Pten phosphatase and tensin homolog JBrowse link NW_004955425 5,007,811 5,091,829 RGD:9068941
PTEN hamartoma tumor syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin alpha 2, smooth muscle JBrowse link NW_004955425 4,023,001 4,039,980 RGD:9068941
G Ankrd22 ankyrin repeat domain 22 JBrowse link NW_004955425 4,123,004 4,149,484 RGD:9068941
G Atad1 ATPase family AAA domain containing 1 JBrowse link NW_004955425 5,118,107 5,180,578 RGD:9068941
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link NW_004955510 5,812,571 5,936,312 RGD:9068941
G Fam25a family with sequence similarity 25 member A JBrowse link NW_004955510 5,975,395 5,977,534 RGD:9068941
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link NW_004955551 2,321,190 2,427,000 RGD:9068941
G Glud1 glutamate dehydrogenase 1 JBrowse link NW_004955510 5,987,811 6,021,001 RGD:9068941
G Lipf lipase F, gastric type JBrowse link NW_004955425 4,267,977 4,284,996 RGD:9068941
G Lipj lipase family member J JBrowse link NW_004955425 4,337,718 4,368,577 RGD:9068941
G Lipk lipase family member K JBrowse link NW_004955425 4,215,214 4,247,584 RGD:9068941
G Lipm lipase family member M JBrowse link NW_004955425 4,150,780 4,170,912 RGD:9068941
G Lipn lipase family member N JBrowse link NW_004955425 4,187,537 4,205,066 RGD:9068941
G Minpp1 multiple inositol-polyphosphate phosphatase 1 JBrowse link NW_004955425 5,329,968 5,359,634 RGD:9068941
G Mmrn2 multimerin 2 JBrowse link NW_004955510 5,943,126 5,957,679 RGD:9068941
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 JBrowse link NW_004955425 5,186,232 5,259,080 RGD:9068941
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link NW_004955420 8,355,415 8,427,024 RGD:9068941
G Pten phosphatase and tensin homolog JBrowse link NW_004955425 5,007,811 5,091,829 RGD:9068941
G Rnls renalase, FAD dependent amine oxidase JBrowse link NW_004955425 4,368,620 4,667,947 RGD:9068941
G Shld2 shieldin complex subunit 2 JBrowse link NW_004955510 6,021,477 6,114,745 RGD:9068941
G Sncg synuclein gamma JBrowse link NW_004955510 5,958,276 5,961,719 RGD:9068941
G Stambpl1 STAM binding protein like 1 JBrowse link NW_004955425 4,045,789 4,091,942 RGD:9068941
tuberous sclerosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link NW_004955409 9,432,835 9,439,680 RGD:9068941
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link NW_004955463 13,702,434 13,720,875 RGD:9068941
G Flna filamin A JBrowse link NW_004955580 874,233 895,172 RGD:9068941
G Ifng interferon gamma JBrowse link NW_004955458 14,643,333 14,648,020 RGD:9068941
G Mmp9 matrix metallopeptidase 9 JBrowse link NW_004955445 11,295,500 11,303,322 RGD:9068941
G Tsc1 TSC complex subunit 1 JBrowse link NW_004955513 2,197,037 2,244,992 RGD:9068941
G Tsc2 TSC complex subunit 2 JBrowse link NW_004955442 15,178,356 15,216,978 RGD:9068941
tuberous sclerosis 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif 13 JBrowse link NW_004955513 2,761,386 2,786,447 RGD:9068941
G Adamtsl2 ADAMTS like 2 JBrowse link NW_004955513 2,849,310 2,879,130 RGD:9068941
G Ak8 adenylate kinase 8 JBrowse link NW_004955513 2,069,187 2,185,469 RGD:9068941
G Brd3 bromodomain containing 3 JBrowse link NW_004955513 3,145,267 3,164,791 RGD:9068941
G Cacfd1 calcium channel flower domain containing 1 JBrowse link NW_004955513 2,787,098 2,796,132 RGD:9068941
G Cel carboxyl ester lipase JBrowse link NW_004955513 2,324,025 2,382,877 RGD:9068941
G Dbh dopamine beta-hydroxylase JBrowse link NW_004955513 2,918,085 2,932,481 RGD:9068941
G Fam163b family with sequence similarity 163 member B JBrowse link NW_004955513 2,880,253 2,903,575 RGD:9068941
G Gbgt1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group) JBrowse link NW_004955513 2,426,623 2,438,019 RGD:9068941
G Gfi1b growth factor independent 1B transcriptional repressor JBrowse link NW_004955513 2,273,267 2,281,850 RGD:9068941
G Gtf3c5 general transcription factor IIIC subunit 5 JBrowse link NW_004955513 2,304,133 2,320,977 RGD:9068941
G Med22 mediator complex subunit 22 JBrowse link NW_004955513 2,697,812 2,704,748 RGD:9068941
G Mymk myomaker, myoblast fusion factor JBrowse link NW_004955513 2,835,466 2,842,325 RGD:9068941
G Ralgds ral guanine nucleotide dissociation stimulator JBrowse link NW_004955513 2,386,293 2,405,161 RGD:9068941
G Rexo4 REX4 homolog, 3'-5' exonuclease JBrowse link NW_004955513 2,745,220 2,754,927 RGD:9068941
G Rpl7a ribosomal protein L7a JBrowse link NW_004955513 2,703,765 2,707,803 RGD:9068941
G Sardh sarcosine dehydrogenase JBrowse link NW_004955513 2,933,918 2,975,645 RGD:9068941
G Slc2a6 solute carrier family 2 member 6 JBrowse link NW_004955513 2,796,086 2,802,051 RGD:9068941
G Spaca9 sperm acrosome associated 9 JBrowse link NW_004955513 2,184,878 2,196,367 RGD:9068941
G Stkld1 serine/threonine kinase like domain containing 1 JBrowse link NW_004955513 2,726,339 2,745,099 RGD:9068941
G Surf1 surfeit 1 JBrowse link NW_004955513 2,707,877 2,711,606 RGD:9068941
G Surf2 surfeit 2 JBrowse link NW_004955513 2,711,605 2,715,667 RGD:9068941
G Surf4 surfeit 4 JBrowse link NW_004955513 2,715,638 2,719,537 RGD:9068941
G Surf6 surfeit 6 JBrowse link NW_004955513 2,691,648 2,696,018 RGD:9068941
G Tsc1 TSC complex subunit 1 JBrowse link NW_004955513 2,197,037 2,244,992 RGD:7240710
RGD:9068941
G Tsc2 TSC complex subunit 2 JBrowse link NW_004955442 15,178,356 15,216,978 RGD:9068941
G Vav2 vav guanine nucleotide exchange factor 2 JBrowse link NW_004955513 2,985,246 3,121,324 RGD:9068941
G Wdr5 WD repeat domain 5 JBrowse link NW_004955513 3,198,655 3,213,754 RGD:9068941
tuberous sclerosis 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Antkmt adenine nucleotide translocase lysine methyltransferase JBrowse link NW_004955442 16,482,450 16,484,164 RGD:9068941
G Baiap3 BAI1 associated protein 3 JBrowse link NW_004955442 15,884,034 15,897,894 RGD:9068941
G C1qtnf8 C1q and TNF related 8 JBrowse link NW_004955442 16,159,901 16,162,152 RGD:9068941
G Cacna1h calcium voltage-gated channel subunit alpha1 H JBrowse link NW_004955442 16,047,965 16,108,862 RGD:9068941
G Ccdc154 coiled-coil domain containing 154 JBrowse link NW_004955442 15,792,593 15,800,410 RGD:9068941
G Ccdc78 coiled-coil domain containing 78 JBrowse link NW_004955442 16,478,219 16,482,452 RGD:9068941
G Chtf18 chromosome transmission fidelity factor 18 JBrowse link NW_004955442 16,414,564 16,423,386 RGD:9068941
G Ciao3 cytosolic iron-sulfur assembly component 3 JBrowse link NW_004955442 16,465,759 16,475,110 RGD:9068941
G Clcn7 chloride voltage-gated channel 7 JBrowse link NW_004955442 15,762,369 15,791,635 RGD:9068941
G Cramp1 cramped chromatin regulator homolog 1 JBrowse link NW_004955442 15,563,545 15,625,163 RGD:9068941
G Eme2 essential meiotic structure-specific endonuclease subunit 2 JBrowse link NW_004955442 15,492,925 15,496,639 RGD:9068941
G Fahd1 fumarylacetoacetate hydrolase domain containing 1 JBrowse link NW_004955442 15,450,066 15,451,797 RGD:9068941
G Fbxl16 F-box and leucine rich repeat protein 16 JBrowse link NW_004955442 16,498,903 16,510,640 RGD:9068941
G Gfer growth factor, augmenter of liver regeneration JBrowse link NW_004955442 15,280,753 15,283,405 RGD:9068941
G Gng13 G protein subunit gamma 13 JBrowse link NW_004955442 16,408,295 16,414,608 RGD:9068941
G Gnptg N-acetylglucosamine-1-phosphate transferase subunit gamma JBrowse link NW_004955442 15,870,409 15,881,552 RGD:9068941
G Hagh hydroxyacylglutathione hydrolase JBrowse link NW_004955442 15,451,910 15,465,211 RGD:9068941
G Haghl hydroxyacylglutathione hydrolase like JBrowse link NW_004955442 16,475,155 16,478,147 RGD:9068941
G Hs3st6 heparan sulfate-glucosamine 3-sulfotransferase 6 JBrowse link NW_004955442 15,337,106 15,344,453 RGD:9068941
G Ifng interferon gamma JBrowse link NW_004955458 14,643,333 14,648,020 RGD:7240710
G Ift140 intraflagellar transport 140 JBrowse link NW_004955442 15,625,429 15,719,006 RGD:9068941
G Igfals insulin like growth factor binding protein acid labile subunit JBrowse link NW_004955442 15,469,602 15,482,115 RGD:9068941
G Jmjd8 jumonji domain containing 8 JBrowse link NW_004955442 16,519,394 16,521,106 RGD:9068941
G Jpt2 Jupiter microtubule associated homolog 2 JBrowse link NW_004955442 15,549,223 15,563,027 RGD:9068941
G Lmf1 lipase maturation factor 1 JBrowse link NW_004955442 16,250,131 16,360,907 RGD:9068941
G LOC102009553 chromosome unknown open reading frame, human C16orf91 JBrowse link NW_004955442 15,820,684 15,821,784 RGD:9068941
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 JBrowse link NW_004955442 15,498,909 15,545,298 RGD:9068941
G Mcrip2 MAPK regulated corepressor interacting protein 2 JBrowse link NW_004955442 16,554,321 16,559,404 RGD:9068941
G Meiob meiosis specific with OB-fold JBrowse link NW_004955442 15,409,344 15,444,996 RGD:9068941
G Metrn meteorin, glial cell differentiation regulator JBrowse link NW_004955442 16,485,482 16,488,949 RGD:9068941
G Mettl26 methyltransferase like 26 JBrowse link NW_004955442 16,571,339 16,572,780 RGD:9068941
G Mrps34 mitochondrial ribosomal protein S34 JBrowse link NW_004955442 15,496,639 15,497,757 RGD:9068941
G Msrb1 methionine sulfoxide reductase B1 JBrowse link NW_004955442 15,322,961 15,328,311 RGD:9068941
G Ndufb10 NADH:ubiquinone oxidoreductase subunit B10 JBrowse link NW_004955442 15,306,688 15,309,281 RGD:9068941
G Nme3 NME/NM23 nucleoside diphosphate kinase 3 JBrowse link NW_004955442 15,497,779 15,498,873 RGD:9068941
G Noxo1 NADPH oxidase organizer 1 JBrowse link NW_004955442 15,288,495 15,290,601 RGD:9068941
G Npw neuropeptide W JBrowse link NW_004955442 15,241,140 15,244,387 RGD:9068941
G Nthl1 nth like DNA glycosylase 1 JBrowse link NW_004955442 15,210,799 15,223,272 RGD:9068941
G Nubp2 nucleotide binding protein 2 JBrowse link NW_004955442 15,482,916 15,486,830 RGD:9068941
G Pigq phosphatidylinositol glycan anchor biosynthesis class Q JBrowse link NW_004955442 16,620,009 16,635,308 RGD:9068941
G Pkd1 polycystin 1, transient receptor potential channel interacting JBrowse link NW_004955442 15,132,555 15,178,377 RGD:9068941
G Ptx4 pentraxin 4 JBrowse link NW_004955442 15,750,881 15,757,906 RGD:9068941
G Rab40c RAB40C, member RAS oncogene family JBrowse link NW_004955442 16,577,843 16,614,132 RGD:9068941
G Rhbdl1 rhomboid like 1 JBrowse link NW_004955442 16,525,009 16,528,780 RGD:9068941
G Rhot2 ras homolog family member T2 JBrowse link NW_004955442 16,528,886 16,534,856 RGD:9068941
G Rnf151 ring finger protein 151 JBrowse link NW_004955442 15,300,228 15,303,645 RGD:9068941
G Rpl3l ribosomal protein L3 like JBrowse link NW_004955442 15,311,336 15,322,578 RGD:9068941
G Rps2 ribosomal protein S2 JBrowse link NW_004955442 15,304,306 15,306,599 RGD:9068941
G Rpusd1 RNA pseudouridine synthase domain containing 1 JBrowse link NW_004955442 16,423,526 16,426,623 RGD:9068941
G Slc9a3r2 SLC9A3 regulator 2 JBrowse link NW_004955442 15,224,214 15,235,372 RGD:9068941
G Sox8 SRY-box transcription factor 8 JBrowse link NW_004955442 16,236,286 16,241,093 RGD:9068941
G Spsb3 splA/ryanodine receptor domain and SOCS box containing 3 JBrowse link NW_004955442 15,486,845 15,493,422 RGD:9068941
G Sstr5 somatostatin receptor 5 JBrowse link NW_004955442 16,169,069 16,176,054 RGD:9068941
G Stub1 STIP1 homology and U-box containing protein 1 JBrowse link NW_004955442 16,521,130 16,523,733 RGD:9068941
G Syngr3 synaptogyrin 3 JBrowse link NW_004955442 15,273,597 15,277,740 RGD:9068941
G Tbl3 transducin beta like 3 JBrowse link NW_004955442 15,290,759 15,297,070 RGD:9068941
G Telo2 telomere maintenance 2 JBrowse link NW_004955442 15,719,082 15,733,527 RGD:9068941
G Tmem204 transmembrane protein 204 JBrowse link NW_004955442 15,678,938 15,701,554 RGD:9068941
G Tsc2 TSC complex subunit 2 JBrowse link NW_004955442 15,178,356 15,216,978 RGD:7240710
G Tsr3 TSR3 ribosome maturation factor JBrowse link NW_004955442 15,881,663 15,884,222 RGD:9068941
G Ube2i ubiquitin conjugating enzyme E2 I JBrowse link NW_004955442 15,902,026 15,913,033 RGD:9068941
G Unkl unk like zinc finger JBrowse link NW_004955442 15,827,352 15,870,561 RGD:9068941
G Wdr24 WD repeat domain 24 JBrowse link NW_004955442 16,513,074 16,519,296 RGD:9068941
G Wdr90 WD repeat domain 90 JBrowse link NW_004955442 16,534,951 16,552,856 RGD:9068941
G Wfikkn1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 JBrowse link NW_004955442 16,573,094 16,577,650 RGD:9068941
G Znf598 zinc finger protein 598, E3 ubiquitin ligase JBrowse link NW_004955442 15,253,649 15,265,420 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11744
    disease of cellular proliferation 5112
      Multiple Primary Neoplasms 134
        Intestinal Polyposis, with Multiple Exostoses 0
        PTEN hamartoma tumor syndrome + 26
        multiple endocrine neoplasia + 9
        tuberous sclerosis + 97
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.