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ONTOLOGY REPORT - ANNOTATIONS


Term:Multiple Primary Neoplasms
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Accession:DOID:9001030 term browser browse the term
Definition:Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.
Synonyms:exact_synonym: Synchronous Multiple Primary Neoplasms;   Synchronous Neoplasm;   multiple primary neoplasm;   synchronous neoplasms
 primary_id: MESH:D009378
 alt_id: RDO:0005711
For additional species annotation, visit the Alliance of Genome Resources.


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Multiple Primary Neoplasms term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnmt3b DNA methyltransferase 3B JBrowse link 2 153,649,411 153,687,730 RGD:9589077
G Mlh1 mutL homolog 1 JBrowse link 9 111,228,228 111,271,786 RGD:1625108
Bannayan-Riley-Ruvalcaba syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 32,397,065 32,466,112 RGD:8554872
G Pten phosphatase and tensin homolog JBrowse link 19 32,757,577 32,826,160 RGD:13592920
RGD:8554872
Cowden syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Egfr epidermal growth factor receptor JBrowse link 11 16,752,203 16,913,907 RGD:8554872
G Gm36566 predicted gene, 36566 JBrowse link 19 32,754,447 32,757,412 RGD:8554872
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 32,397,065 32,466,112 RGD:8554872
G Pten phosphatase and tensin homolog JBrowse link 19 32,757,577 32,826,160 RGD:8554872
RGD:7240710
RGD:13592920
G Rint1 RAD50 interactor 1 JBrowse link 5 23,787,698 23,823,584 RGD:8554872
G Sdhb succinate dehydrogenase complex, subunit B, iron sulfur (Ip) JBrowse link 4 140,961,271 140,979,198 RGD:8554872
Cowden Syndrome 4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gm36566 predicted gene, 36566 JBrowse link 19 32,754,447 32,757,412 RGD:7240710
Cowden Syndrome 5 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 32,397,065 32,466,112 RGD:7240710
RGD:8554872
Cowden Syndrome 6 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:8554872
RGD:7240710
Cowden Syndrome 7 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sec23b SEC23 homolog B, COPII coat complex component JBrowse link 2 144,556,229 144,590,753 RGD:8554872
RGD:7240710
Cowden-Like Syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 32,397,065 32,466,112 RGD:8554872
G Pten phosphatase and tensin homolog JBrowse link 19 32,757,577 32,826,160 RGD:8554872
familial medullary thyroid carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Insrr insulin receptor-related receptor JBrowse link 3 87,796,908 87,816,101 RGD:8554872
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 JBrowse link 3 87,778,244 87,795,242 RGD:8554872
G Prlr prolactin receptor JBrowse link 15 10,177,238 10,349,190 RGD:13592920
G Ret ret proto-oncogene JBrowse link 6 118,151,748 118,197,744 RGD:7240710
RGD:8554872
RGD:11554173
Macrocephaly Mesodermal Hamartoma Spectrum term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:8554872
multiple endocrine neoplasia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 6 134,920,401 134,925,525 RGD:2293616
RGD:8554872
G Ghrl ghrelin JBrowse link 6 113,716,119 113,719,911 RGD:12904888
G Ghsr growth hormone secretagogue receptor JBrowse link 3 27,371,351 27,379,235 RGD:12904888
G Gpr19 G protein-coupled receptor 19 JBrowse link 6 134,869,092 134,898,194 RGD:8554872
G Men1 multiple endocrine neoplasia 1 JBrowse link 19 6,334,979 6,340,894 RGD:8554872
G Ret ret proto-oncogene JBrowse link 6 118,151,748 118,197,744 RGD:11554173
RGD:8554872
multiple endocrine neoplasia type 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf2 fibroblast growth factor 2 JBrowse link 3 37,348,477 37,410,106 RGD:2317763
G Men1 multiple endocrine neoplasia 1 JBrowse link 19 6,334,979 6,340,894 RGD:1601327
RGD:8554872
RGD:13592920
RGD:11554173
RGD:7240710
RGD:1581203
RGD:2317334
RGD:2317335
RGD:2317314
RGD:2317293
RGD:619590
RGD:2317313
RGD:2317331
RGD:2317303
RGD:2317327
RGD:1601326
RGD:2317347
G Ret ret proto-oncogene JBrowse link 6 118,151,748 118,197,744 RGD:8554872
multiple endocrine neoplasia type 2A term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ret ret proto-oncogene JBrowse link 6 118,151,748 118,197,744 RGD:2324920
RGD:8554872
RGD:11554173
RGD:7240710
multiple endocrine neoplasia type 2B term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ret ret proto-oncogene JBrowse link 6 118,151,748 118,197,744 RGD:7240710
RGD:8554872
RGD:13592920
multiple endocrine neoplasia type 4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 6 134,920,401 134,925,525 RGD:7240710
RGD:8554872
G Gpr19 G protein-coupled receptor 19 JBrowse link 6 134,869,092 134,898,194 RGD:8554872
G Ret ret proto-oncogene JBrowse link 6 118,151,748 118,197,744 RGD:8554872
Proteus syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:5509063
RGD:8554872
RGD:7240710
G Pten phosphatase and tensin homolog JBrowse link 19 32,757,577 32,826,160 RGD:11554173
RGD:8554872
PTEN hamartoma tumor syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin, alpha 2, smooth muscle, aorta JBrowse link 19 34,240,336 34,255,585 RGD:8554872
G Ankrd22 ankyrin repeat domain 22 JBrowse link 19 34,122,549 34,166,041 RGD:8554872
G Atad1 ATPase family, AAA domain containing 1 JBrowse link 19 32,672,558 32,739,787 RGD:8554872
G Bmpr1a bone morphogenetic protein receptor, type 1A JBrowse link 14 34,411,061 34,503,336 RGD:8554872
G Fam25c family with sequence similarity 25, member C JBrowse link 14 34,351,882 34,358,339 RGD:8554872
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 7 130,162,451 130,266,808 RGD:11554173
G Glud1 glutamate dehydrogenase 1 JBrowse link 14 34,310,727 34,345,033 RGD:8554872
G Gm36566 predicted gene, 36566 JBrowse link 19 32,754,447 32,757,412 RGD:8554872
G Lipf lipase, gastric JBrowse link 19 33,961,248 33,976,813 RGD:8554872
G Lipk lipase, family member K JBrowse link 19 34,008,254 34,047,903 RGD:8554872
G Lipm lipase, family member M JBrowse link 19 34,100,943 34,122,687 RGD:8554872
G Lipn lipase, family member N JBrowse link 19 34,067,058 34,085,946 RGD:8554872
G Minpp1 multiple inositol polyphosphate histidine phosphatase 1 JBrowse link 19 32,485,769 32,515,370 RGD:8554872
G Mmrn2 multimerin 2 JBrowse link 14 34,375,504 34,404,287 RGD:8554872
G Ms4a6d membrane-spanning 4-domains, subfamily A, member 6D JBrowse link 19 11,586,606 11,604,804 RGD:8554872
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 JBrowse link 19 32,595,669 32,667,187 RGD:8554872
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 32,397,065 32,466,112 RGD:8554872
G Pten phosphatase and tensin homolog JBrowse link 19 32,757,577 32,826,160 RGD:1302552
RGD:8554872
RGD:11554173
RGD:12859041
RGD:12859035
RGD:12802361
RGD:12802356
G Rnls renalase, FAD-dependent amine oxidase JBrowse link 19 33,137,740 33,392,295 RGD:8554872
G Shld2 shieldin complex subunit 2 JBrowse link 14 34,236,948 34,310,651 RGD:8554872
G Sncg synuclein, gamma JBrowse link 14 34,370,274 34,374,669 RGD:8554872
G Stambpl1 STAM binding protein like 1 JBrowse link 19 34,190,378 34,240,333 RGD:8554872
tuberous sclerosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 14 46,383,525 46,390,669 RGD:9068443
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 8 27,260,327 27,275,656 RGD:1549429
G Flna filamin, alpha JBrowse link X 74,223,461 74,249,854 RGD:11565117
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:11554173
G Mmp9 matrix metallopeptidase 9 JBrowse link 2 164,940,326 164,955,850 RGD:8547829
G Tsc1 TSC complex subunit 1 JBrowse link 2 28,640,993 28,691,172 RGD:1624196
RGD:9068941
RGD:8554872
RGD:13592920
RGD:11073512
RGD:11570511
RGD:11062248
RGD:11554173
G Tsc2 TSC complex subunit 2 JBrowse link 17 24,595,816 24,632,676 RGD:8554872
RGD:13592920
RGD:11062248
RGD:11568672
RGD:11554173
tuberous sclerosis 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abo ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase, transferase B, alpha 1-3-galactosyltransferase) JBrowse link 2 26,842,496 26,864,995 RGD:8554872
G Adamts13 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 JBrowse link 2 26,973,361 27,009,625 RGD:8554872
G Adamtsl2 ADAMTS-like 2 JBrowse link 2 27,079,336 27,108,981 RGD:8554872
G Ak8 adenylate kinase 8 JBrowse link 2 28,698,275 28,813,165 RGD:8554872
G Brd3 bromodomain containing 3 JBrowse link 2 27,445,576 27,507,657 RGD:8554872
G Cacfd1 calcium channel flower domain containing 1 JBrowse link 2 27,009,855 27,021,090 RGD:8554872
G Cel carboxyl ester lipase JBrowse link 2 28,555,819 28,563,403 RGD:8554872
G Dbh dopamine beta hydroxylase JBrowse link 2 27,165,507 27,183,204 RGD:8554872
G Fam163b family with sequence similarity 163, member B JBrowse link 2 27,110,379 27,142,477 RGD:8554872
G Gbgt1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 JBrowse link 2 28,479,354 28,506,030 RGD:8554872
G Gfi1b growth factor independent 1B JBrowse link 2 28,609,450 28,621,982 RGD:8554872
G Gm25541 predicted gene, 25541 JBrowse link 2 27,539,805 27,539,930 RGD:8554872
G Gtf3c5 general transcription factor IIIC, polypeptide 5 JBrowse link 2 28,566,245 28,583,279 RGD:8554872
G Med22 mediator complex subunit 22 JBrowse link 2 26,905,267 26,910,642 RGD:8554872
G Mymk myomaker, myoblast fusion factor JBrowse link 2 27,061,636 27,072,161 RGD:8554872
G Obp2b odorant binding protein 2B JBrowse link 2 25,714,109 25,740,124 RGD:8554872
G Ralgds ral guanine nucleotide dissociation stimulator JBrowse link 2 28,513,089 28,553,082 RGD:8554872
G Rexo4 REX4, 3'-5' exonuclease JBrowse link 2 26,953,559 26,964,386 RGD:8554872
G Rpl7a ribosomal protein L7A JBrowse link 2 26,910,685 26,913,312 RGD:8554872
G Sardh sarcosine dehydrogenase JBrowse link 2 27,188,393 27,248,332 RGD:8554872
G Slc2a6 solute carrier family 2 (facilitated glucose transporter), member 6 JBrowse link 2 27,021,363 27,028,000 RGD:8554872
G Spaca9 sperm acrosome associated 9 JBrowse link 2 28,692,080 28,699,651 RGD:8554872
G Stkld1 serine/threonine kinase-like domain containing 1 JBrowse link 2 26,933,521 26,953,496 RGD:8554872
G Surf1 surfeit gene 1 JBrowse link 2 26,913,378 26,916,610 RGD:8554872
G Surf2 surfeit gene 2 JBrowse link 2 26,916,372 26,920,187 RGD:8554872
G Surf4 surfeit gene 4 JBrowse link 2 26,920,041 26,933,776 RGD:8554872
G Surf6 surfeit gene 6 JBrowse link 2 26,890,418 26,902,887 RGD:8554872
G Tsc1 TSC complex subunit 1 JBrowse link 2 28,640,993 28,691,172 RGD:7240710
RGD:8554872
RGD:11570507
G Tsc2 TSC complex subunit 2 JBrowse link 17 24,595,816 24,632,676 RGD:8554872
G Vav2 vav 2 oncogene JBrowse link 2 27,262,104 27,427,608 RGD:8554872
G Wdr5 WD repeat domain 5 JBrowse link 2 27,515,147 27,536,535 RGD:8554872
tuberous sclerosis 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Antkmt adenine nucleotide translocase lysine methyltransferase JBrowse link 17 25,790,500 25,792,787 RGD:8554872
G Baiap3 BAI1-associated protein 3 JBrowse link 17 25,242,659 25,256,364 RGD:8554872
G BC003965 cDNA sequence BC003965 JBrowse link 17 25,184,561 25,187,662 RGD:8554872
G Cacna1h calcium channel, voltage-dependent, T type, alpha 1H subunit JBrowse link 17 25,374,285 25,436,334 RGD:8554872
G Ccdc154 coiled-coil domain containing 154 JBrowse link 17 25,162,175 25,171,913 RGD:8554872
G Ccdc78 coiled-coil domain containing 78 JBrowse link 17 25,786,580 25,790,513 RGD:8554872
G Chtf18 CTF18, chromosome transmission fidelity factor 18 JBrowse link 17 25,719,030 25,727,434 RGD:8554872
G Ciao3 cytosolic iron-sulfur assembly component 3 JBrowse link 17 25,773,776 25,783,332 RGD:8554872
G Clcn7 chloride channel, voltage-sensitive 7 JBrowse link 17 25,133,378 25,162,103 RGD:8554872
G Cramp1l cramped chromatin regulator homolog 1 JBrowse link 17 24,961,226 25,015,840 RGD:8554872
G Eme2 essential meiotic structure-specific endonuclease subunit 2 JBrowse link 17 24,892,152 24,895,087 RGD:8554872
G Fahd1 fumarylacetoacetate hydrolase domain containing 1 JBrowse link 17 24,848,896 24,850,302 RGD:8554872
G Fbxl16 F-box and leucine-rich repeat protein 16 JBrowse link 17 25,808,461 25,821,262 RGD:8554872
G Gfer growth factor, augmenter of liver regeneration JBrowse link 17 24,693,190 24,696,156 RGD:8554872
G Gng13 guanine nucleotide binding protein (G protein), gamma 13 JBrowse link 17 25,717,172 25,719,102 RGD:8554872
G Gnptg N-acetylglucosamine-1-phosphotransferase, gamma subunit JBrowse link 17 25,232,224 25,240,328 RGD:8554872
G Hagh hydroxyacyl glutathione hydrolase JBrowse link 17 24,839,781 24,864,450 RGD:8554872
G Haghl hydroxyacylglutathione hydrolase-like JBrowse link 17 25,779,843 25,785,586 RGD:8554872
G Hs3st6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 JBrowse link 17 24,752,988 24,758,690 RGD:8554872
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:7240710
G Ift140 intraflagellar transport 140 JBrowse link 17 25,016,083 25,099,499 RGD:8554872
G Igfals insulin-like growth factor binding protein, acid labile subunit JBrowse link 17 24,877,844 24,882,011 RGD:8554872
G Jmjd8 jumonji domain containing 8 JBrowse link 17 25,829,043 25,831,843 RGD:8554872
G Jpt2 Jupiter microtubule associated homolog 2 JBrowse link 17 24,942,470 24,960,623 RGD:8554872
G Lmf1 lipase maturation factor 1 JBrowse link 17 25,579,174 25,662,831 RGD:8554872
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 JBrowse link 17 24,897,506 24,936,977 RGD:8554872
G Mcrip2 MAPK regulated corepressor interacting protein 2 JBrowse link 17 25,863,698 25,868,740 RGD:8554872
G Meiob meiosis specific with OB domains JBrowse link 17 24,804,301 24,839,788 RGD:8554872
G Metrn meteorin, glial cell differentiation regulator JBrowse link 17 25,794,571 25,797,045 RGD:8554872
G Mettl26 methyltransferase like 26 JBrowse link 17 25,875,500 25,877,163 RGD:8554872
G Mrps34 mitochondrial ribosomal protein S34 JBrowse link 17 24,895,120 24,896,289 RGD:8554872
G Msln mesothelin JBrowse link 17 25,748,613 25,754,378 RGD:8554872
G Msrb1 methionine sulfoxide reductase B1 JBrowse link 17 24,736,593 24,742,778 RGD:8554872
G Ndufb10 NADH:ubiquinone oxidoreductase subunit B10 JBrowse link 17 24,722,060 24,724,423 RGD:8554872
G Nme3 NME/NM23 nucleoside diphosphate kinase 3 JBrowse link 17 24,896,500 24,897,531 RGD:8554872
G Noxo1 NADPH oxidase organizer 1 JBrowse link 17 24,696,234 24,700,530 RGD:8554872
G Npw neuropeptide W JBrowse link 17 24,657,329 24,658,552 RGD:8554872
G Nthl1 nth (endonuclease III)-like 1 (E.coli) JBrowse link 17 24,632,680 24,638,838 RGD:8554872
G Nubp2 nucleotide binding protein 2 JBrowse link 17 24,882,611 24,886,350 RGD:8554872
G Pigq phosphatidylinositol glycan anchor biosynthesis, class Q JBrowse link 17 25,926,420 25,942,881 RGD:8554872
G Pkd1 polycystin 1, transient receptor poteintial channel interacting JBrowse link 17 24,548,689 24,596,514 RGD:8554872
G Ptx4 pentraxin 4 JBrowse link 17 25,120,697 25,125,293 RGD:8554872
G Rab40c Rab40C, member RAS oncogene family JBrowse link 17 25,882,114 25,919,714 RGD:8554872
G Rhbdl1 rhomboid like 1 JBrowse link 17 25,834,465 25,837,127 RGD:8554872
G Rhot2 ras homolog family member T2 JBrowse link 17 25,838,457 25,844,525 RGD:8554872
G Rnf151 ring finger protein 151 JBrowse link 17 24,715,839 24,718,057 RGD:8554872
G Rpl3l ribosomal protein L3-like JBrowse link 17 24,727,826 24,736,143 RGD:8554872
G Rps2 ribosomal protein S2 JBrowse link 17 24,718,121 24,721,927 RGD:8554872
G Rpusd1 RNA pseudouridylate synthase domain containing 1 JBrowse link 17 25,727,703 25,731,464 RGD:8554872
G Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 JBrowse link 17 24,639,281 24,650,305 RGD:8554872
G Snhg9 small nucleolar RNA host gene 9 JBrowse link 17 24,719,531 24,719,965 RGD:8554872
G Sox8 SRY (sex determining region Y)-box 8 JBrowse link 17 25,565,893 25,570,686 RGD:8554872
G Spsb3 splA/ryanodine receptor domain and SOCS box containing 3 JBrowse link 17 24,885,982 24,892,150 RGD:8554872
G Sstr5 somatostatin receptor 5 JBrowse link 17 25,489,875 25,497,288 RGD:8554872
G Stub1 STIP1 homology and U-Box containing protein 1 JBrowse link 17 25,830,634 25,832,919 RGD:8554872
G Syngr3 synaptogyrin 3 JBrowse link 17 24,685,092 24,689,949 RGD:8554872
G Tbl3 transducin (beta)-like 3 JBrowse link 17 24,700,653 24,707,653 RGD:8554872
G Telo2 telomere maintenance 2 JBrowse link 17 25,099,569 25,115,974 RGD:8554872
G Tmem204 transmembrane protein 204 JBrowse link 17 25,057,702 25,081,114 RGD:8554872
G Tpsab1 tryptase alpha/beta 1 JBrowse link 17 25,343,245 25,345,562 RGD:8554872
G Tpsb2 tryptase beta 2 JBrowse link 17 25,366,308 25,368,096 RGD:8554872
G Tpsg1 tryptase gamma 1 JBrowse link 17 25,369,195 25,374,442 RGD:8554872
G Tsc2 TSC complex subunit 2 JBrowse link 17 24,595,816 24,632,676 RGD:7240710
RGD:8554872
RGD:11554173
G Tsr3 TSR3 20S rRNA accumulation JBrowse link 17 25,240,141 25,242,799 RGD:8554872
G Ube2i ubiquitin-conjugating enzyme E2I JBrowse link 17 25,260,510 25,275,799 RGD:8554872
G Unkl unkempt family like zinc finger JBrowse link 17 25,188,361 25,234,443 RGD:8554872
G Wdr24 WD repeat domain 24 JBrowse link 17 25,823,627 25,828,730 RGD:8554872
G Wdr90 WD repeat domain 90 JBrowse link 17 25,844,734 25,861,515 RGD:8554872
G Wfikkn1 WAP, FS, Ig, KU, and NTR-containing protein 1 JBrowse link 17 25,877,628 25,880,858 RGD:8554872
G Zfp598 zinc finger protein 598 JBrowse link 17 24,669,687 24,682,023 RGD:8554872

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13272
    disease of cellular proliferation 5730
      Multiple Primary Neoplasms 143
        Intestinal Polyposis, with Multiple Exostoses 0
        PTEN hamartoma tumor syndrome + 27
        multiple endocrine neoplasia + 10
        tuberous sclerosis + 104
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.