ONTOLOGY REPORT - ANNOTATIONS


Term:Bronchopulmonary Dysplasia
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Accession:DOID:9001403 term browser browse the term
Definition:A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS.
Synonyms:primary_id: MESH:D001997;   RDO:0005073
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Bronchopulmonary Dysplasia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:11537057
G Bid BH3 interacting domain death agonist JBrowse link 4 153,439,812 153,465,247 RGD:11537057
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:11537057
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:11537057
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:11537057
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:5130750
G Ccl7 C-C motif chemokine ligand 7 JBrowse link 10 69,423,083 69,424,933 RGD:5130981
G Cd209c CD209c molecule JBrowse link 12 2,837,991 2,846,709 RGD:5131185
G Chi3l1 chitinase 3 like 1 JBrowse link 13 51,022,844 51,030,797 RGD:4892651
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:5134972
G Dag1 dystroglycan 1 JBrowse link 8 116,980,501 116,993,182 RGD:11537474
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:4144841
G Epas1 endothelial PAS domain protein 1 JBrowse link 6 10,306,508 10,385,239 RGD:10395385
G Flt1 FMS-related tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:10402122
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:12792215
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:4142520
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:12792215
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:10395385
RGD:11537057
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:4143172
RGD:11554173
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:4143172
RGD:12910846
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:12910846
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:4891007
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:5129685
G Muc1 mucin 1, cell surface associated JBrowse link 2 188,543,137 188,547,874 RGD:5131170
G Postn periostin JBrowse link 2 143,656,820 143,688,087 RGD:11554173
G Scgb1a1 secretoglobin family 1A member 1 JBrowse link 1 225,279,698 225,283,246 RGD:5144211
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:13208551
G Sftpa1 surfactant protein A1 JBrowse link 16 18,716,019 18,719,404 RGD:4143384
RGD:4144876
G Sftpb surfactant protein B JBrowse link 4 100,166,855 100,175,941 RGD:4143405
RGD:4143418
RGD:4143384
G Sftpd surfactant protein D JBrowse link 16 18,753,535 18,766,100 RGD:4143384
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:12904049
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:11537057
G Txn1 thioredoxin 1 JBrowse link 5 75,049,735 75,057,731 RGD:11554173
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:13432055

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14823
    Wounds and Injuries 798
      Thoracic Injuries 238
        Lung Injury 234
          Ventilator-Induced Lung Injury 49
            Bronchopulmonary Dysplasia 34
Path 2
Term Annotations click to browse term
  disease 14823
    disease of anatomical entity 13997
      respiratory system disease 2375
        lower respiratory tract disease 1412
          lung disease 1370
            Lung Injury 234
              Ventilator-Induced Lung Injury 49
                Bronchopulmonary Dysplasia 34
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.