Term:Bronchopulmonary Dysplasia
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Accession:DOID:9001403 term browser browse the term
Definition:A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS.
Synonyms:primary_id: MESH:D001997;   RDO:0005073
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Bronchopulmonary Dysplasia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link NW_004936664 2,968,103 2,973,652 RGD:9068941
G Bid BH3 interacting domain death agonist JBrowse link NW_004936807 708,340 750,127 RGD:9068941
G Casp3 caspase 3 JBrowse link NW_004936554 4,571,072 4,593,765 RGD:9068941
G Casp8 caspase 8 JBrowse link NW_004936726 554,627 596,334 RGD:9068941
G Casp9 caspase 9 JBrowse link NW_004936474 3,178,097 3,196,130 RGD:9068941
G Cat catalase JBrowse link NW_004936533 3,601,270 3,637,128 RGD:9068941
G Chi3l1 chitinase 3 like 1 JBrowse link NW_004936567 1,411,080 1,418,332 RGD:9068941
G Dag1 dystroglycan 1 JBrowse link NW_004936529 1,099,510 1,171,587 RGD:9068941
G Edn1 endothelin 1 JBrowse link NW_004936534 885,489 892,292 RGD:9068941
G Epas1 endothelial PAS domain protein 1 JBrowse link NW_004936508 5,855,748 5,938,879 RGD:9068941
G Flt1 fms related tyrosine kinase 1 JBrowse link NW_004936472 23,442,946 23,617,523 RGD:9068941
G Gstp1 glutathione S-transferase pi 1 JBrowse link NW_004936599 2,197,681 2,200,642 RGD:9068941
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link NW_004936495 5,770,988 5,816,157 RGD:9068941
G Il1b interleukin 1 beta JBrowse link NW_004936783 1,251,678 1,256,807 RGD:9068941
G Il1rn interleukin 1 receptor antagonist JBrowse link NW_004936783 1,447,158 1,466,331 RGD:9068941
G Mif macrophage migration inhibitory factor JBrowse link NW_004936619 1,207,058 1,208,010 RGD:9068941
G Mmp9 matrix metallopeptidase 9 JBrowse link NW_004936514 7,038,240 7,045,873 RGD:9068941
G Muc1 mucin 1, cell surface associated JBrowse link NW_004936580 4,691,870 4,694,092 RGD:9068941
G Postn periostin JBrowse link NW_004936472 31,644,778 31,677,572 RGD:9068941
G Scgb1a1 secretoglobin family 1A member 1 JBrowse link NW_004936581 798,738 801,614 RGD:9068941
G Serpine1 serpin family E member 1 JBrowse link NW_004936543 1,032,543 1,040,956 RGD:9068941
G Sftpb surfactant protein B JBrowse link NW_004936712 1,614,979 1,621,207 RGD:9068941
G Sftpd surfactant protein D JBrowse link NW_004936716 60,754 73,010 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004936727 1,936,066 1,937,766 RGD:9068941
G Tp53 tumor protein p53 JBrowse link NW_004936595 919,807 935,367 RGD:9068941
G Txn thioredoxin JBrowse link NW_004936559 2,811,786 2,822,528 RGD:9068941
G Vdr vitamin D receptor JBrowse link NW_004936512 5,741,836 5,800,999 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 10743
    Wounds and Injuries 726
      Thoracic Injuries 200
        Lung Injury 197
          Ventilator-Induced Lung Injury 41
            Bronchopulmonary Dysplasia 27
Path 2
Term Annotations click to browse term
  disease 10743
    disease of anatomical entity 10269
      respiratory system disease 2056
        lower respiratory tract disease 1254
          lung disease 1213
            Lung Injury 197
              Ventilator-Induced Lung Injury 41
                Bronchopulmonary Dysplasia 27
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.