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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Taste Disorders
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Accession:DOID:9001661 term browser browse the term
Definition:Conditions characterized by an alteration in gustatory function or perception. Taste disorders are frequently associated with OLFACTION DISORDERS. Additional potential etiologies include METABOLIC DISEASES; DRUG TOXICITY; and taste pathway disorders (e.g., TASTE BUD diseases; FACIAL NERVE DISEASES; GLOSSOPHARYNGEAL NERVE DISEASES; and BRAIN STEM diseases).
Synonyms:exact_synonym: Metallic Taste;   Metallic Tastes;   Primary Taste Disorder;   Primary Taste Disorders;   Secondary Taste Disorder;   Secondary Taste Disorders;   Taste Disorder;   Taste Disorder, Anterior Tongue;   Taste Disorder, Posterior Tongue;   Taste Disorder, Primary, Bitter;   Taste Disorder, Primary, Salt;   Taste Disorder, Primary, Sweet;   Taste Disorder, Secondary, Bitter;   Taste Disorder, Secondary, Salt;   Taste Disorder, Secondary, Sweet
 primary_id: MESH:D013651;   RDO:0004779
For additional species annotation, visit the Alliance of Genome Resources.


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Taste Disorders term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G En2 engrailed homeobox 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29953887 NCBI chr 4:438,668...444,508
Ensembl chr 4:438,668...444,501
JBrowse link
G Fas Fas cell surface death receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22536412 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Gcg glucagon ISO CTD Direct Evidence: marker/mechanism CTD PMID:21824258 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:7080326 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
Thiourea Tasting term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tas2r138 taste receptor, type 2, member 138 ISO ClinVar Annotator: match by synonym: Phenylthiocarbamide tasting
ClinVar Annotator: match by term: Phenylthiocarbamide tasting
OMIM
ClinVar
PMID:12595690, PMID:28492532 NCBI chr 4:68,831,221...68,832,216
Ensembl chr 4:68,831,221...68,832,216
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16045
    Pathological Conditions, Signs and Symptoms 8735
      Signs and Symptoms 5235
        Neurologic Manifestations 4188
          Sensation Disorders 1019
            Taste Disorders 5
              Ageusia 0
              Dysgeusia 0
              Thiourea Tasting 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.