ONTOLOGY REPORT - ANNOTATIONS


Term:Disease Susceptibility
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Accession:DOID:9002174 term browser browse the term
Definition:A constitution or condition of the body which makes the tissues react in special ways to certain extrinsic stimuli and thus tends to make the individual more than usually susceptible to certain diseases.
Synonyms:exact_synonym: Diatheses;   Diathesis;   Disease Susceptibilities
 primary_id: MESH:D004198;   RDO:0001523
For additional species annotation, visit the Alliance of Genome Resources.


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Disease Susceptibility term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:11554173
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:11554173
G Mt-nd6 mitochondrially encoded NADH dehydrogenase 6 JBrowse link MT 13,543 14,061 RGD:11554173
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 JBrowse link 8 6,811,543 6,917,534 RGD:11554173
G Tspan12 tetraspanin 12 JBrowse link 4 48,852,823 48,953,240 RGD:11554173
Bovine Tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:11554173
C6 Deficiency, Subtotal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C6 complement C6 JBrowse link 2 54,460,333 54,533,801 RGD:8554872
Genetic Predisposition to Disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abat 4-aminobutyrate aminotransferase JBrowse link 10 7,093,406 7,200,439 RGD:11554173
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:11554173
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:11554173
G Adh1 alcohol dehydrogenase 1 (class I) JBrowse link 2 243,550,655 243,562,243 RGD:11554173
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:11554173
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:11554173
G Alad aminolevulinate dehydratase JBrowse link 5 78,368,867 78,379,206 RGD:11554173
G Aldh2 aldehyde dehydrogenase 2 family member JBrowse link 12 40,466,418 40,498,813 RGD:11554173
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 JBrowse link 15 27,849,943 27,852,083 RGD:11554173
G Bap1 Brca1 associated protein 1 JBrowse link 16 7,336,685 7,345,511 RGD:11554173
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:11554173
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:11554173
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:11554173
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:11554173
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:11554173
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:11554173
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:11554173
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:11554173
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:11554173
G Kcnj8 potassium voltage-gated channel subfamily J member 8 JBrowse link 4 176,783,287 176,789,143 RGD:11554173
G LOC100364500 RT1 class I, locus CE11-like JBrowse link 20 2,704,153 2,707,111 RGD:11554173
G Mt2A metallothionein 2A JBrowse link 19 11,307,966 11,308,740 RGD:11554173
G Ogg1 8-oxoguanine DNA glycosylase JBrowse link 4 145,282,828 145,289,367 RGD:11554173
G Rad51 RAD51 recombinase JBrowse link 3 110,918,240 110,942,920 RGD:11554173
G Tgfa transforming growth factor alpha JBrowse link 4 117,961,877 118,045,923 RGD:11554173
G Xrcc3 X-ray repair cross complementing 3 JBrowse link 6 136,366,917 136,380,751 RGD:11554173
Latent Tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tlr1 toll-like receptor 1 JBrowse link 14 45,062,662 45,065,014 RGD:8554872
Meningeal Tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:5128510
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:10449456
multidrug-resistant tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:5147828
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:5147828
Ocular Tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:7364832
pleural tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl22 C-C motif chemokine ligand 22 JBrowse link 19 10,674,189 10,681,145 RGD:4891473
G Ccr2 C-C motif chemokine receptor 2 RGD:4145106
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:4145106
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:4143226
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:4143226
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:5129700
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:4144193
G Tnc tenascin C JBrowse link 5 79,789,686 79,874,555 RGD:4889594
pulmonary tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:5128854
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:5686405
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:4890411
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 JBrowse link 7 104,670,076 104,951,090 RGD:11554173
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:5129500
G Ccl1 C-C motif chemokine ligand 1 JBrowse link 10 69,534,976 69,537,836 RGD:4891409
RGD:4891408
G Ccl19 C-C motif chemokine ligand 19 JBrowse link 5 58,181,025 58,182,969 RGD:5130906
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:4891439
RGD:11554173
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:4891879
RGD:4892112
G Ccr2 C-C motif chemokine receptor 2 RGD:734715
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:4892094
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:4144205
G Cd209 CD209 molecule JBrowse link 12 2,406,879 2,413,324 RGD:11554173
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:4892339
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:5131284
RGD:5131287
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:5135037
G Cxcl6 C-X-C motif chemokine ligand 6 JBrowse link 14 18,860,201 18,920,839 RGD:5135246
G Cyba cytochrome b-245 alpha chain JBrowse link 19 55,249,634 55,257,824 RGD:4780358
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:4140932
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:4140932
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:5135524
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:4145649
G Il15 interleukin 15 JBrowse link 19 23,542,606 23,624,366 RGD:4990461
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:4889836
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:4142835
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:4143180
RGD:5147843
RGD:4143179
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:4143180
RGD:4143174
RGD:4143179
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:5128486
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:5128550
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:5128510
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:4143257
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:5128632
G Irf1 interferon regulatory factor 1 JBrowse link 10 39,109,530 39,116,532 RGD:5128719
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:4889999
G Lta lymphotoxin alpha JBrowse link 20 4,851,889 4,854,677 RGD:4143234
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:4889452
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:4891004
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:5130746
G Nat2 N-acetyltransferase 2 JBrowse link 16 23,960,709 23,991,570 RGD:4140932
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:5131510
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:4144122
G Plaur plasminogen activator, urokinase receptor JBrowse link 1 81,328,171 81,344,954 RGD:6483832
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 JBrowse link 2 206,342,066 206,390,348 RGD:6484723
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:5147614
G Sftpa1 surfactant protein A1 JBrowse link 16 18,716,019 18,719,404 RGD:4144874
RGD:4144875
G Slc11a1 solute carrier family 11 member 1 JBrowse link 9 81,655,590 81,666,697 RGD:5684974
G Tap1 transporter 1, ATP binding cassette subfamily B member JBrowse link 20 3,979,302 3,989,669 RGD:6482248
G Tap2 transporter 2, ATP binding cassette subfamily B member JBrowse link 20 3,995,544 4,009,587 RGD:5147851
G Tlr1 toll-like receptor 1 JBrowse link 14 45,062,662 45,065,014 RGD:4889525
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:4145304
RGD:4145320
RGD:4145323
RGD:4145355
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:4144106
RGD:4144122
RGD:4144205
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:5130704
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:4143388
RGD:4142835
RGD:4143395
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:4889849
RGD:4889830
RGD:4889842
RGD:4889845
RGD:4889853
renal tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:5128510
RGD:7207069
tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:6767307
G Btnl2 butyrophilin-like 2 JBrowse link 20 4,140,184 4,156,365 RGD:9685035
RGD:9685036
G Ccl1 C-C motif chemokine ligand 1 JBrowse link 10 69,534,976 69,537,836 RGD:4891408
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8554872
RGD:7240710
G Cd209 CD209 molecule JBrowse link 12 2,406,879 2,413,324 RGD:8554872
RGD:7240710
G Cd209c CD209c molecule JBrowse link 12 2,837,991 2,846,709 RGD:5131181
RGD:5131186
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:4892329
G Ciita class II, major histocompatibility complex, transactivator JBrowse link 10 5,212,621 5,260,641 RGD:5491205
G Cish cytokine inducible SH2-containing protein JBrowse link 8 116,054,547 116,059,494 RGD:8554872
RGD:7240710
G Coro1a coronin 1A JBrowse link 1 198,123,883 198,128,890 RGD:11554173
G Cxcl9 C-X-C motif chemokine ligand 9 JBrowse link 14 17,228,832 17,233,743 RGD:5135308
G Has1 hyaluronan synthase 1 JBrowse link 1 59,720,612 59,732,409 RGD:9588638
G Hp haptoglobin JBrowse link 19 42,096,255 42,100,805 RGD:11554173
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:8554872
RGD:7240710
G Ifngr1 interferon gamma receptor 1 JBrowse link 1 15,062,380 15,080,815 RGD:4144122
RGD:7240710
RGD:8554872
G Il12rb1 interleukin 12 receptor subunit beta 1 JBrowse link 16 20,370,722 20,383,576 RGD:8554872
G Il15 interleukin 15 JBrowse link 19 23,542,606 23,624,366 RGD:4987456
G Il22 interleukin 22 JBrowse link 7 61,236,037 61,240,502 RGD:5147402
G Irgm immunity-related GTPase M JBrowse link 10 34,213,885 34,221,968 RGD:7240710
G Mapkapk3 mitogen-activated protein kinase-activated protein kinase 3 JBrowse link 8 116,012,126 116,046,012 RGD:8554872
G Mc3r melanocortin 3 receptor JBrowse link 3 170,252,901 170,253,998 RGD:7240710
G RT1-Ba RT1 class II, locus Ba JBrowse link 20 4,066,133 4,070,726 RGD:11554173
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:5147605
RGD:5147633
G Slc11a1 solute carrier family 11 member 1 JBrowse link 9 81,655,590 81,666,697 RGD:5684931
RGD:7240710
RGD:8554872
RGD:11554173
RGD:1331525
G Sp110 SP110 nuclear body protein JBrowse link 9 92,593,909 92,618,867 RGD:8554872
RGD:7240710
G Sp140 SP140 nuclear body protein JBrowse link 9 92,618,088 92,665,431 RGD:8554872
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:1581371
G Tirap TIR domain containing adaptor protein JBrowse link 8 36,382,029 36,399,625 RGD:11554173
RGD:7240710
RGD:8554872
G Tlr1 toll-like receptor 1 JBrowse link 14 45,062,662 45,065,014 RGD:7246918
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:8554872
RGD:7240710
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:4144821
G Tlr6 toll-like receptor 6 JBrowse link 14 45,024,351 45,041,188 RGD:7246918
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:4143229
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link 5 163,136,390 163,167,299 RGD:5131209
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:4889839
Tumor Predisposition Syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:8554872
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:8554872
G Bap1 Brca1 associated protein 1 JBrowse link 16 7,336,685 7,345,511 RGD:7240710
RGD:8554872
G Bard1 BRCA1 associated RING domain 1 JBrowse link 9 78,297,723 78,368,777 RGD:8554872
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:8554872
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:8554872
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:8554872
G Brip1 BRCA1 interacting protein C-terminal helicase 1 JBrowse link 10 73,507,009 73,632,742 RGD:8554872
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:8554872
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:8554872
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:8554872
G Chek2 checkpoint kinase 2 JBrowse link 12 51,845,574 51,878,098 RGD:8554872
G Epm2aip1 EPM2A interacting protein 1 JBrowse link 8 119,524,039 119,531,387 RGD:8554872
G Fh fumarate hydratase JBrowse link 13 93,651,486 93,677,371 RGD:8554872
G Flcn folliculin JBrowse link 10 46,153,185 46,172,331 RGD:8554872
G Max MYC associated factor X JBrowse link 6 99,984,260 100,011,460 RGD:8554872
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link 4 44,747,467 44,854,628 RGD:8554872
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:8554872
G Mre11a MRE11 homolog A, double strand break repair nuclease JBrowse link 8 13,304,355 13,350,329 RGD:8554872
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:8554872
G Msh6 mutS homolog 6 JBrowse link 6 11,644,565 11,662,389 RGD:8554872
G Mutyh mutY DNA glycosylase JBrowse link 5 135,663,328 135,675,348 RGD:8554872
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:8554872
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:8554872
G Osgin2 oxidative stress induced growth inhibitor family member 2 JBrowse link 5 29,663,131 29,683,634 RGD:8554872
G Palb2 partner and localizer of BRCA2 JBrowse link 1 192,064,586 192,088,547 RGD:8554872
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:8554872
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:8554872
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:8554872
G Rad51c RAD51 paralog C JBrowse link 10 74,697,713 74,724,004 RGD:8554872
G Rad51d RAD51 paralog D JBrowse link 10 70,222,703 70,241,352 RGD:8554872
G Ret ret proto-oncogene JBrowse link 4 150,202,170 150,249,196 RGD:8554872
G RGD1311251 similar to RIKEN cDNA 4930550C14 JBrowse link 8 57,983,168 58,012,474 RGD:8554872
G Sdha succinate dehydrogenase complex flavoprotein subunit A JBrowse link 1 31,545,631 31,570,601 RGD:8554872
G Sdhaf2 succinate dehydrogenase complex assembly factor 2 JBrowse link 1 226,543,671 226,572,414 RGD:8554872
G Sdhb succinate dehydrogenase complex iron sulfur subunit B JBrowse link 5 159,484,378 159,505,063 RGD:8554872
G Sdhc succinate dehydrogenase complex subunit C JBrowse link 13 89,498,047 89,518,979 RGD:8554872
G Sdhd succinate dehydrogenase complex subunit D JBrowse link 8 55,028,125 55,037,604 RGD:8554872
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:8554872
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:8554872
G Tmem127 transmembrane protein 127 JBrowse link 3 119,677,575 119,690,371 RGD:8554872
G Toe1 target of EGR1, exonuclease JBrowse link 5 135,659,733 135,663,299 RGD:8554872
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:8554872
G Tsc1 TSC complex subunit 1 JBrowse link 3 7,219,955 7,269,063 RGD:8554872
G Tsc2 TSC complex subunit 2 JBrowse link 10 13,962,006 13,996,684 RGD:8554872
G Vhl von Hippel-Lindau tumor suppressor JBrowse link 4 145,580,869 145,587,835 RGD:8554872

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14919
    Pathological Conditions, Signs and Symptoms 7740
      Pathologic Processes 4923
        Disease Attributes 446
          Disease Susceptibility 153
            C6 Deficiency, Subtotal 1
            Echo Virus 11 Sensitivity 0
            Genetic Predisposition to Disease + 71
            tuberculosis + 81
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.