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ONTOLOGY REPORT - ANNOTATIONS


Term:Hyperplasia
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Accession:DOID:9002221 term browser browse the term
Definition:An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
Synonyms:exact_synonym: Hyperplasias
 primary_id: MESH:D006965;   RDO:0001143
For additional species annotation, visit the Alliance of Genome Resources.


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Hyperplasia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc8 ATP binding cassette subfamily C member 8 JBrowse link 1 102,110,708 102,191,287 RGD:2325205
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 9 121,705,897 121,725,736 RGD:2325255
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:11554173
G Apc APC, WNT signaling pathway regulator JBrowse link 18 27,011,710 27,106,323 RGD:2317191
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:704377
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:734632
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:2293156
G Brd4 bromodomain containing 4 JBrowse link 7 14,222,101 14,303,055 RGD:11554173
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:8661765
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:2314685
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:11554173
G Cdc25a cell division cycle 25A JBrowse link 8 117,953,223 117,971,552 RGD:2764000
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:13792775
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:8552677
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:8699513
G Col2a1 collagen type II alpha 1 chain JBrowse link 7 139,454,945 139,484,403 RGD:11554173
G Csk C-terminal Src kinase JBrowse link 8 62,405,714 62,424,707 RGD:5134365
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:5131466
G Glp1r glucagon-like peptide 1 receptor JBrowse link 20 9,586,075 9,626,228 RGD:11554173
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:11554173
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:11554173
G Hspb1 heat shock protein family B (small) member 1 JBrowse link 12 23,839,390 23,841,051 RGD:11554173
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:7495757
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:11554173
G Il9 interleukin 9 JBrowse link 17 8,558,827 8,561,950 RGD:11554173
G Kcnk1 potassium two pore domain channel subfamily K member 1 JBrowse link 19 58,823,836 58,862,926 RGD:11554173
G Kdm1a lysine demethylase 1A JBrowse link 5 154,909,003 154,965,171 RGD:11554173
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:11554173
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:11554173
G Mapk6 mitogen-activated protein kinase 6 JBrowse link 8 82,328,013 82,351,108 RGD:11554173
G Mat1a methionine adenosyltransferase 1A JBrowse link 16 18,690,649 18,709,135 RGD:11554173
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:7207219
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:2325718
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:11554173
G Mycn MYCN proto-oncogene, bHLH transcription factor JBrowse link 6 38,222,554 38,228,419 RGD:11554173
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:11554173
G Ogg1 8-oxoguanine DNA glycosylase JBrowse link 4 145,282,828 145,289,367 RGD:11554173
G Pam peptidylglycine alpha-amidating monooxygenase JBrowse link 9 111,028,543 111,177,588 RGD:6483575
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha JBrowse link 2 118,831,350 118,861,456 RGD:11554173
RGD:13207413
G Prg4 proteoglycan 4 JBrowse link 13 67,672,588 67,688,902 RGD:11554173
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:11554173
G Rln3 relaxin 3 JBrowse link 19 25,164,497 25,166,528 RGD:11554173
G Tcf7l2 transcription factor 7 like 2 JBrowse link 1 276,686,911 276,730,517 RGD:11554173
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:11554173
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1299231
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:2315458
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:11554173
Epidermal Hyperplasia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:8695988
G Srsf6 serine and arginine rich splicing factor 6 JBrowse link 3 159,305,345 159,310,668 RGD:11039481
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:8699499
Hypoinsulinemic Hypoglycemia with Hemihypertrophy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt2 AKT serine/threonine kinase 2 JBrowse link 1 84,400,939 84,451,223 RGD:7240710
RGD:8554872
Intimal Hyperplasia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccr2 C-C motif chemokine receptor 2 RGD:8661636
G Cdk2 cyclin dependent kinase 2 JBrowse link 7 3,124,953 3,132,533 RGD:10448975
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:8661636
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:10395302
G Foxo3 forkhead box O3 JBrowse link 20 46,428,078 46,519,156 RGD:10402197
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:11520787
G Klf5 Kruppel-like factor 5 JBrowse link 15 83,703,796 83,722,921 RGD:1581748
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:10412065
G Mmp7 matrix metallopeptidase 7 JBrowse link 8 5,893,253 5,900,965 RGD:9685369
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:11534002
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:10448975
G Pdgfd platelet derived growth factor D JBrowse link 8 4,441,010 4,666,754 RGD:9854640
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:10449504
Neointima term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:8695998
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:11554173
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 12 39,553,903 39,603,326 RGD:13782090
G Atp7a ATPase copper transporting alpha JBrowse link X 77,076,085 77,193,644 RGD:11554173
G Axl Axl receptor tyrosine kinase JBrowse link 1 82,550,892 82,580,761 RGD:631894
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:11558011
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:8699512
RGD:9068412
G Cybb cytochrome b-245 beta chain JBrowse link X 14,578,330 14,610,049 RGD:11040762
G Drd4 dopamine receptor D4 JBrowse link 1 214,278,296 214,282,818 RGD:13506962
G Ece1 endothelin converting enzyme 1 JBrowse link 5 156,215,469 156,318,652 RGD:7244170
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 JBrowse link 1 259,692,020 259,818,922 RGD:9685444
G Epc1 enhancer of polycomb homolog 1 JBrowse link 17 57,303,968 57,394,975 RGD:9587795
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:2289992
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:11341672
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:8655643
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:10402089
G Flt1 FMS-related tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:10402128
RGD:10402146
G Foxo4 forkhead box O4 JBrowse link X 71,155,284 71,162,158 RGD:10402361
RGD:10402362
G Gas6 growth arrest specific 6 JBrowse link 16 81,213,364 81,243,824 RGD:631894
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:10755571
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1580477
G Iqgap1 IQ motif containing GTPase activating protein 1 JBrowse link 1 142,525,041 142,615,673 RGD:11049552
G Klf5 Kruppel-like factor 5 JBrowse link 15 83,703,796 83,722,921 RGD:1581746
RGD:11554173
G Lgals3 galectin 3 JBrowse link 15 24,153,602 24,165,537 RGD:9685205
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 15,412,603 15,613,752 RGD:10412321
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:11554173
RGD:13207403
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:11554173
RGD:13207403
G Myb MYB proto-oncogene, transcription factor JBrowse link 1 16,658,178 16,690,135 RGD:11532744
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link 17 32,131,847 32,158,559 RGD:11073699
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:2289992
G Pak1 p21 (RAC1) activated kinase 1 JBrowse link 1 162,768,156 162,883,356 RGD:10041068
RGD:11533945
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:10413907
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:10449489
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:11087557
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:11087557
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 JBrowse link 8 21,669,236 21,680,615 RGD:8693429
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:10041068
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:729766
G S1pr1 sphingosine-1-phosphate receptor 1 JBrowse link 2 218,654,406 218,658,761 RGD:11554173
G Selp selectin P JBrowse link 13 82,428,914 82,464,629 RGD:729766
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:8547879
RGD:8547913
G Ssh1 slingshot protein phosphatase 1 JBrowse link 12 48,403,184 48,447,964 RGD:11535005
G Stat4 signal transducer and activator of transcription 4 JBrowse link 9 54,340,649 54,457,753 RGD:5509614
G Tfpi tissue factor pathway inhibitor JBrowse link 3 71,852,738 71,902,127 RGD:11060274
RGD:11341672
G Timm44 translocase of inner mitochondrial membrane 44 JBrowse link 12 2,517,006 2,533,707 RGD:13463598
G Yy1 YY1 transcription factor JBrowse link 6 132,702,443 132,726,848 RGD:9588268

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  disease 14759
    Pathological Conditions, Signs and Symptoms 7254
      Pathologic Processes 4755
        Hyperplasia 119
          Epidermal Hyperplasia 3
          Facial Hemihypertrophy + 1
          Hemihyperplasia, Isolated 0
          Hypoinsulinemic Hypoglycemia with Hemihypertrophy 1
          Intimal Hyperplasia + 57
          Pseudoangiomatous Stromal Hyperplasia 0
          Sebaceous Gland Hyperplasia, Familial Presenile 0
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