Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


Term:Shy-Drager Syndrome
go back to main search page
Accession:DOID:9002322 term browser browse the term
Definition:A progressive neurodegenerative condition of the central and autonomic nervous systems characterized by atrophy of the preganglionic lateral horn neurons of the thoracic spinal cord. This disease is generally considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Affected individuals present in the fifth or sixth decade with ORTHOSTASIS and bladder dysfunction; and later develop FECAL INCONTINENCE; anhidrosis; ATAXIA; IMPOTENCE; and alterations of tone suggestive of basal ganglia dysfunction. (From Adams et al., Principles of Neurology, 6th ed, p536)
Synonyms:exact_synonym: Dysautonomia Orthostatic Hypotension Syndrome;   Dysautonomic Orthostatic Hypotension;   Dysautonomic Orthostatic Hypotensions;   Idiopathic Orthostatic Hypotension, Shy Drager Type;   Progressive Autonomic Failure;   dysautonomia-orthostatic hypotension syndromes;   progressive autonomic failures
 primary_id: MESH:D012791
 alt_id: RDO:0006570
For additional species annotation, visit the Alliance of Genome Resources.

show annotations for term's descendants       view all columns           Sort by:
Shy-Drager Syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Avp arginine vasopressin JBrowse link 3 123,117,482 123,119,460 RGD:11554173
G Coq2 coenzyme Q2, polyprenyltransferase JBrowse link 14 10,581,102 10,601,093 RGD:8554872
G Mapt microtubule-associated protein tau JBrowse link 10 92,289,002 92,386,517 RGD:8554872

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15619
    syndrome 5154
      multiple system atrophy 29
        Shy-Drager Syndrome 3
Path 2
Term Annotations click to browse term
  disease 15619
    disease of anatomical entity 14948
      nervous system disease 10216
        central nervous system disease 8092
          brain disease 7561
            movement disease 1000
              multiple system atrophy 29
                Shy-Drager Syndrome 3
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.