ONTOLOGY REPORT - ANNOTATIONS


Term:Cardiotoxicity
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Accession:DOID:9002371 term browser browse the term
Definition:Damage to the heart or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
Synonyms:exact_synonym: Cardiac Toxicities;   Cardiac Toxicity;   Cardiotoxicities
 primary_id: MESH:D066126;   RDO:0015989
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Cardiotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:11554173
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:11554173
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:11554173
G Hbegf heparin-binding EGF-like growth factor JBrowse link 18 29,330,302 29,340,185 RGD:11554173
G Mir208a microRNA 208a JBrowse link 15 33,613,451 33,613,533 RGD:11554173
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:11533645
G Nppb natriuretic peptide B JBrowse link 5 164,796,176 164,797,538 RGD:11554173
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:11554173
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:11554173
G Rarg retinoic acid receptor, gamma JBrowse link 7 143,840,739 143,863,206 RGD:11554173
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:11554173
Anthracycline-induced Cardiotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:11041175
G Capn2 calpain 2 JBrowse link 13 100,878,649 100,928,811 RGD:13792617
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 80,293,574 80,307,334 RGD:11252190

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  disease 14920
    Wounds and Injuries 800
      Radiation Injuries 64
        Cardiotoxicity 16
          Anthracycline-induced Cardiotoxicity 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.