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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Foreign-Body Reaction
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Accession:DOID:9002438 term browser browse the term
Definition:Chronic inflammation and granuloma formation around irritating foreign bodies.
Synonyms:primary_id: MESH:D005549;   RDO:0005626
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
Foreign-Body Reaction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15949549 RGD:1581336 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
Granuloma, Foreign-Body term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr9 toll-like receptor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19797157 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16023
    Wounds and Injuries 835
      Foreign Bodies 2
        Foreign-Body Reaction 2
          Granuloma, Foreign-Body 1
          Implant Capsular Contracture 0
Path 2
Term Annotations click to browse term
  disease 16023
    disease of anatomical entity 15278
      Immune & Inflammatory Diseases 3513
        Inflammation 2172
          Foreign-Body Reaction 2
            Granuloma, Foreign-Body 1
            Implant Capsular Contracture 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.