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Term:Blast Crisis
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Accession:DOID:9002473 term browser browse the term
Definition:An advanced phase of chronic myelogenous leukemia, characterized by a rapid increase in the proportion of immature white blood cells (blasts) in the blood and bone marrow to greater than 30%.
Synonyms:exact_synonym: Blast Crises;   Blast Phase;   Blast Phases
 primary_id: MESH:D001752;   RDO:0005018
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Blast Crisis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aicda activation-induced cytidine deaminase JBrowse link 4 155,359,909 155,371,104 RGD:11554173
G Bcr BCR activator of RhoGEF and GTPase JBrowse link 20 14,421,250 14,546,406 RGD:11554173
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:734951
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:10755566
G Mir150 microRNA 150 JBrowse link 1 101,115,974 101,116,058 RGD:13782140
G Tcn2 transcobalamin 2 JBrowse link 14 84,173,992 84,189,299 RGD:11060122

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15620
    disease of cellular proliferation 5796
      Neoplastic Processes 606
        Carcinogenesis 145
          Neoplastic Cell Transformation 134
            Blast Crisis 6
Path 2
Term Annotations click to browse term
  disease 15620
    disease of anatomical entity 14949
      Hemic and Lymphatic Diseases 1723
        hematopoietic system disease 1451
          Hematologic Neoplasms 790
            hematologic cancer 789
              bone marrow cancer 290
                myeloid neoplasm 229
                  chronic myeloid leukemia 85
                    Blast Crisis 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.