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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Pancreatic Neoplasms
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Accession:DOID:9003100 term browser browse the term
Synonyms:exact_synonym: Pancreas Neoplasms;   pancreas neoplasm;   pancreatic neoplasm
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
Pancreatic Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nek8 NIMA-related kinase 8 ISO ClinVar Annotator: match by term: Pancreatic Neoplasms ClinVar PMID:20581473 NCBI chr10:65,404,489...65,439,059
Ensembl chr10:65,425,771...65,437,143
JBrowse link
G Stk11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Pancreatic Neoplasms ClinVar PMID:21189378 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513
JBrowse link
G Stk33 serine/threonine kinase 33 ISO ClinVar Annotator: match by term: Pancreatic Neoplasms ClinVar PMID:20581473 NCBI chr 1:173,872,744...174,051,768
Ensembl chr 1:173,872,736...174,047,572
JBrowse link
G Ttk Ttk protein kinase ISO ClinVar Annotator: match by term: Pancreatic Neoplasms ClinVar PMID:20581473 NCBI chr 8:91,368,065...91,405,995
Ensembl chr 8:91,368,111...91,405,993
JBrowse link
Adult Pancreatic Cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12203118 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
duodenal gastrinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Men1 menin 1 ISO associated with Neuroendocrine Tumors; DNA:loss of heterozygosity: : RGD PMID:17135306 RGD:2317341 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
Familial Pancreatic Carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 ISO mRNA:increased expression:pancreas, carcinoma (human) RGD PMID:16815451 RGD:5685662 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
gastrinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igf1r insulin-like growth factor 1 receptor ISO mRNA and protein: increased expression::poor prognosis for high expression RGD PMID:15867218 RGD:7242847 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Men1 menin 1 ISO DNA:mutations: :
CTD Direct Evidence: marker/mechanism
CTD PMID:17961653, PMID:15944766 RGD:2317354 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase severity ISO associated with Zollinger-Ellison Syndrome; mRNA:increased expression:tumor (human) RGD PMID:12114431 RGD:2317605 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO DNA:hypomethylation:promoter (human) RGD PMID:17278096 RGD:2317340 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO mRNA:decreased expression:pancreatic islet RGD PMID:12114701, PMID:8421107 RGD:2324976, RGD:2324977 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
Gastro-Enteropancreatic Neuroendocrine Tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd53 Cd53 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 2:209,489,279...209,537,098
Ensembl chr 2:209,489,279...209,537,087
JBrowse link
G Cd86 CD86 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr10:5,212,621...5,260,641
Ensembl chr10:5,213,350...5,260,608
JBrowse link
G Eomes eomesodermin ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 8:127,144,367...127,152,618
Ensembl chr 8:127,144,903...127,151,493
JBrowse link
G Gata3 GATA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr14:3,058,035...3,073,332
Ensembl chr14:3,058,993...3,068,371
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr14:91,782,281...91,867,828
Ensembl chr14:91,782,354...91,867,424
JBrowse link
G Ikzf3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr10:86,420,757...86,509,454
Ensembl chr10:86,421,582...86,509,454
JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il2rb interleukin 2 receptor subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 7:119,701,338...119,716,238
Ensembl chr 7:119,701,251...119,716,238
JBrowse link
G Notch2 notch receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 2:200,187,184...200,320,403
Ensembl chr 2:200,187,179...200,320,215
JBrowse link
G Pou2f2 POU class 2 homeobox 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 1:81,966,791...82,049,116
Ensembl chr 1:81,964,104...82,004,538
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Runx3 RUNX family transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 5:153,507,093...153,531,137
Ensembl chr 5:153,507,093...153,531,137
JBrowse link
G Serpina1 serpin family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
Glucagonoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btc betacellulin ISO protein:increased expression:pancreas RGD PMID:10724350 RGD:2326087 NCBI chr14:18,231,854...18,270,621
Ensembl chr14:18,231,860...18,272,484
JBrowse link
G Men1 menin 1 ISO DNA:deletion:exon
CTD Direct Evidence: marker/mechanism
CTD PMID:17961653, PMID:20138042 RGD:2317288 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO mRNA:decreased expression:pancreatic islet RGD PMID:12114701, PMID:8421107 RGD:2324976, RGD:2324977 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Sstr4 somatostatin receptor 4 ISO RGD PMID:8132773 RGD:2324994 NCBI chr 3:142,739,781...142,741,644
Ensembl chr 3:142,739,781...142,741,644
JBrowse link
insulinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin ISO protein:increased expression:pancreas, plasma RGD PMID:11331218 RGD:2325319 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Btc betacellulin ISO protein:increased expression:pancreas RGD PMID:10724350 RGD:2326087 NCBI chr14:18,231,854...18,270,621
Ensembl chr14:18,231,860...18,272,484
JBrowse link
G Cd40 CD40 molecule ISO RGD PMID:17982058 RGD:5491180 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 ISO protein:increased expression:pancreas RGD PMID:19013212 RGD:2317608 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Ins2 insulin 2 ISO protein:altered expression:blood
protein:altered localization:pancreas
RGD PMID:8175958, PMID:2565624 RGD:2317266, RGD:2317268 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Men1 menin 1 disease_progression ISO DNA:deletion:exon
ClinVar Annotator: match by term: Insulinoma
CTD Direct Evidence: marker/mechanism
DNA:deletions:exons
ClinVar
CTD
PMID:17961653, PMID:25741868, PMID:30311386, PMID:12941803, PMID:20138042, PMID:19208834 RGD:2317292, RGD:2317288, RGD:2317310 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
G Ncam1 neural cell adhesion molecule 1 ISO protein:increased expression:pancreas RGD PMID:8972754 RGD:2326080 NCBI chr 8:53,836,797...54,134,881
Ensembl chr 8:53,839,098...53,901,358
JBrowse link
G Rps15 ribosomal protein S15 IEP RGD PMID:3019805 RGD:61740 NCBI chr 7:12,282,134...12,283,573
Ensembl chr 7:12,282,109...12,283,608
JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO protein:increased expression:pancreatic B cell
mRNA:decreased expression:pancreatic islet
RGD PMID:12114701, PMID:8421107 RGD:2324976, RGD:2324977 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Tgfa transforming growth factor alpha ISO protein:increased expression:pancreas RGD PMID:8712689 RGD:2317472 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO mRNA, protein:decreased expression:pancreatic islet RGD PMID:18058603 RGD:2325017 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
Islet Cell Adenomatosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mafa MAF bZIP transcription factor A ISO ClinVar Annotator: match by term: Islet cell adenomatosis ClinVar
OMIM
PMID:25741868, PMID:29339498 NCBI chr 7:116,779,368...116,781,815
Ensembl chr 7:116,780,681...116,781,766
JBrowse link
islet cell tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcsk1 proprotein convertase subtilisin/kexin type 1 IEP protein:increased expression:insulinoma (rat) RGD PMID:7925129 RGD:2308920 NCBI chr 2:91,450,162...91,497,091
Ensembl chr 2:91,450,162...91,497,091
JBrowse link
Islet Cell Tumor Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif1b kinesin family member 1B ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:18334619, PMID:18726616 NCBI chr 5:165,994,803...166,133,497
Ensembl chr 5:165,938,576...166,133,491
JBrowse link
G Mpz myelin protein zero ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:12807974, PMID:17468193, PMID:19454582, PMID:23342407, PMID:24033266, PMID:25741868 NCBI chr13:89,524,204...89,530,070
Ensembl chr13:89,524,329...89,530,068
JBrowse link
G Ret ret proto-oncogene ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:2660074, PMID:3078962, PMID:7536460, PMID:7824936, PMID:7845675, PMID:7906417, PMID:7906866, PMID:7911697, PMID:7977365, PMID:8570194, PMID:8595427, PMID:8782503, PMID:8797874, PMID:8880581, PMID:8918855, PMID:9242375, PMID:9620546, PMID:9681850, PMID:9839497, PMID:10369718, PMID:10445857, PMID:10679286, PMID:11230481, PMID:11351254, PMID:15277225, PMID:15281979, PMID:15320968, PMID:16715139, PMID:17108110, PMID:17848262, PMID:18058472, PMID:18073307, PMID:18209889, PMID:18252215, PMID:18322301, PMID:18541894, PMID:19041016, PMID:19240193, PMID:19255327, PMID:19826964, PMID:19906784, PMID:20065189, PMID:20368568, PMID:20516206, PMID:20847059, PMID:21253810, PMID:21422803, PMID:21455200, PMID:21470995, PMID:21479187, PMID:21551259, PMID:21765987, PMID:21810974, PMID:21986619, PMID:22025146, PMID:22199277, PMID:22233172, PMID:22359510, PMID:22676344, PMID:22992277, PMID:23056499, PMID:23067224, PMID:24033266, PMID:24728327, PMID:25157968, PMID:25637381, PMID:25741868, PMID:26084817, PMID:26332594, PMID:26467025, PMID:26489027, PMID:27379493, PMID:27539324, PMID:27807060, PMID:28492532, PMID:28946813 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:12364472, PMID:12618761, PMID:14500403, PMID:15328326, PMID:16314641, PMID:16317055, PMID:17102082, PMID:17200167, PMID:18362451, PMID:18840642, PMID:19454582, PMID:19802898, PMID:22835832, PMID:23083876, PMID:23175444, PMID:23282968, PMID:23512077, PMID:24033266, PMID:24102379, PMID:24659481, PMID:25298897, PMID:25741868, PMID:25972245, PMID:26642834, PMID:26719882, PMID:28374168, PMID:28492532, PMID:28503760, PMID:28973655, PMID:29386252, PMID:29951630, PMID:30352407 NCBI chr 5:159,484,378...159,505,063
Ensembl chr 5:159,484,370...159,505,064
JBrowse link
G Sdhc succinate dehydrogenase complex subunit C ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:12807974, PMID:17468193, PMID:19454582, PMID:23342407, PMID:24033266, PMID:25741868 NCBI chr13:89,498,047...89,518,979
Ensembl chr13:89,498,048...89,518,939
JBrowse link
G Sdhd succinate dehydrogenase complex subunit D ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:10657297, PMID:11156372, PMID:11526495, PMID:12007193, PMID:12111639, PMID:12386824, PMID:12696072, PMID:14557476, PMID:15032977, PMID:15623805, PMID:18678321, PMID:21565294, PMID:21979946, PMID:22584711, PMID:22703879, PMID:23175444, PMID:23666964, PMID:24033266, PMID:24728327, PMID:24886695, PMID:25149476, PMID:25694510, PMID:25695889, PMID:25741868, PMID:26467025, PMID:27153395, PMID:27279923, PMID:28128698, PMID:28164237, PMID:28492532, PMID:29386252 NCBI chr 8:55,028,125...55,037,604
Ensembl chr 8:55,028,125...55,037,604
JBrowse link
Melanoma-Pancreatic Cancer Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Melanoma-pancreatic cancer syndrome
ClinVar Annotator: match by term: FAMILIAL ATYPICAL MULTIPLE MOLE MELANOMA-PANCREATIC CARCINOMA SYNDROME
OMIM
ClinVar
PMID:7566978, PMID:7632931, PMID:7647780, PMID:7666917, PMID:7670475, PMID:7718873, PMID:7777061, PMID:7780957, PMID:7882348, PMID:7923152, PMID:7970734, PMID:7972006, PMID:7987387, PMID:7987388, PMID:8012957, PMID:8552158, PMID:8561866, PMID:8570179, PMID:8573142, PMID:8595411, PMID:8603820, PMID:8668202, PMID:8710906, PMID:8755727, PMID:8841025, PMID:9049826, PMID:9133447, PMID:9166859, PMID:9185756, PMID:9212218, PMID:9324288, PMID:9389568, PMID:9425228, PMID:9473234, PMID:9516223, PMID:9660926, PMID:9699728, PMID:9751050, PMID:9782052, PMID:9808520, PMID:9823374, PMID:9856796, PMID:9916806, PMID:9935245, PMID:10229204, PMID:10389768, PMID:10390011, PMID:10398427, PMID:10400925, PMID:10498896, PMID:10508477, PMID:10627132, PMID:10719365, PMID:10738302, PMID:10854221, PMID:10869234, PMID:10874641, PMID:10951521, PMID:10956390, PMID:11156381, PMID:11360201, PMID:11506491, PMID:11556834, PMID:11579459, PMID:11595726, PMID:11687599, PMID:11807902, PMID:11815963, PMID:12072543, PMID:12352668, PMID:12417040, PMID:12461329, PMID:12485439, PMID:12532425, PMID:12549483, PMID:12606942, PMID:12700603, PMID:12853981, PMID:12894891, PMID:14508519, PMID:14679123, PMID:14735200, PMID:15075790, PMID:15122588, PMID:15146471, PMID:15173226, PMID:15235029, PMID:15705881, PMID:15761864, PMID:15860862, PMID:15937071, PMID:15945100, PMID:16169933, PMID:16234564, PMID:16354195, PMID:16397522, PMID:16614725, PMID:16818274, PMID:16896043, PMID:16905682, PMID:17047042, PMID:17218939, PMID:17255954, PMID:17370310, PMID:17397031, PMID:17713569, PMID:18023021, PMID:18025365, PMID:18178632, PMID:18335566, PMID:18337833, PMID:18363633, PMID:18519632, PMID:18573309, PMID:18803811, PMID:18843795, PMID:18981015, PMID:18983535, PMID:19141585, PMID:19260062, PMID:19320745, PMID:19360740, PMID:19523171, PMID:19571771, PMID:19690981, PMID:19799798, PMID:20093296, PMID:20132244, PMID:20340136, PMID:20505745, PMID:20539244, PMID:20653773, PMID:20876876, PMID:21150883, PMID:21325014, PMID:21462282, PMID:21619050, PMID:21801156, PMID:21893440, PMID:22292911, PMID:22368299, PMID:22636603, PMID:22703879, PMID:22841127, PMID:22995991, PMID:23190892, PMID:23371019, PMID:23613284, PMID:24033266, PMID:24185512, PMID:24659262, PMID:24728327, PMID:24733792, PMID:24737347, PMID:25064638, PMID:25186627, PMID:25318351, PMID:25356972, PMID:25372287, PMID:25479140, PMID:25741868, PMID:25780468, PMID:25787093, PMID:25803691, PMID:25846456, PMID:25980754, PMID:26104880, PMID:26206375, PMID:26225579, PMID:26295973, PMID:26381259, PMID:26467025, PMID:26474073, PMID:26483394, PMID:26498684, PMID:26581427, PMID:26601054, PMID:26650572, PMID:26658419, PMID:26670561, PMID:26681309, PMID:26775776, PMID:26845104, PMID:26976419, PMID:27181379, PMID:27473757, PMID:27626068, PMID:27701467, PMID:27756164, PMID:27960642, PMID:27978560, PMID:28135145, PMID:28146043, PMID:28410231, PMID:28492532, PMID:28521409, PMID:28592523, PMID:28599463, PMID:28640387, PMID:28726808, PMID:28765326, PMID:28767289, PMID:28830827, PMID:28866070, PMID:28873162, PMID:28944238, PMID:28979722, PMID:29263814, PMID:29533785, PMID:29541281, PMID:29758216, PMID:29774366, PMID:30207590, PMID:30311386, PMID:30339520, PMID:31921681 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
non-functioning pancreatic endocrine tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk4 cyclin-dependent kinase 4 ISO associated with multiple endocrine neoplasia type 1;mRNA:increased expression:islet of Langerhans (human) RGD PMID:29149451 RGD:13781946 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk6 cyclin-dependent kinase 6 ISO associated with multiple endocrine neoplasia type 1;mRNA:increased expression:islet of Langerhans (human) RGD PMID:29149451 RGD:13781946 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
pancreatic acinar cell adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO DNA:missense mutation, gene fusions:multiple (human) RGD PMID:25266736 RGD:13462041 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
pancreatic adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb1 adhesion G protein-coupled receptor B1 ISO mRNA:decreased expression:pancreas RGD PMID:11875720 RGD:13831350 NCBI chr 7:115,766,484...115,828,514 JBrowse link
G Akt3 AKT serine/threonine kinase 3 severity ISO mRNA:increased expression:pancreas (human) RGD PMID:27919956 RGD:13451128 NCBI chr13:95,076,308...95,348,913
Ensembl chr13:95,081,390...95,348,913
JBrowse link
G Cbr4 carbonyl reductase 4 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:25741868, PMID:28492532 NCBI chr16:31,944,328...31,972,553
Ensembl chr16:31,956,753...31,972,507
JBrowse link
G Ccnd1 cyclin D1 severity ISO protein:increased expression:pancreas (human) RGD PMID:25053516 RGD:13462053 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdk4 cyclin-dependent kinase 4 treatment ISO human cells in a mouse model RGD PMID:22509328 RGD:13792559 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk6 cyclin-dependent kinase 6 treatment ISO human cells in a mouse model RGD PMID:25050737 RGD:13782144 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO DNA:missense mutations:cds:p.V126D, p.A148T (human)
ClinVar Annotator: match by term: Pancreatic adenocarcinoma
ClinVar PMID:7780957, PMID:8521414, PMID:8595405, PMID:8723678, PMID:9324288, PMID:9751050, PMID:9823374, PMID:10491434, PMID:11477665, PMID:11500805, PMID:11687599, PMID:12072543, PMID:16234564, PMID:16896043, PMID:16905682, PMID:21462282, PMID:25157968, PMID:25356972, PMID:25741868, PMID:26619011, PMID:26681309, PMID:26775776, PMID:28492532, PMID:28830827, PMID:29983899, PMID:16397522 RGD:8552283 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Ctnnb1 catenin beta 1 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:9065402, PMID:9294210, PMID:9500465, PMID:9927029, PMID:10192393, PMID:10398436, PMID:10435629, PMID:10655994, PMID:10666372, PMID:25157968, PMID:26619011, PMID:26822237 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO RGD PMID:21448932 RGD:11352272 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G E2f1 E2F transcription factor 1 treatment ISO Human cells in a mouse model RGD PMID:28797284 RGD:13838736 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:16397024, PMID:23220880, PMID:26619011 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Gnas GNAS complex locus ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:1594625, PMID:1944469, PMID:2549426, PMID:3720010, PMID:7739708, PMID:8766942, PMID:9626141, PMID:12727968, PMID:12970318, PMID:15126527, PMID:16507630, PMID:21835143, PMID:23536913, PMID:24855271, PMID:25157968, PMID:26619011 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gstt1 glutathione S-transferase theta 1 ISO RGD PMID:11854392 RGD:14700985 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:11150980, PMID:12210337, PMID:12835555, PMID:14608654, PMID:16155195, PMID:16170316, PMID:16329078, PMID:16372351, PMID:16443854, PMID:16835863, PMID:16881968, PMID:16969868, PMID:17054105, PMID:17211612, PMID:17250658, PMID:17384584, PMID:17412879, PMID:17979197, PMID:18039947, PMID:18042262, PMID:18247425, PMID:18470943, PMID:18978862, PMID:19206176, PMID:19213030, PMID:19255327, PMID:19371735, PMID:19382114, PMID:19669404, PMID:19773371, PMID:20660566, PMID:20859122, PMID:20979192, PMID:21438134, PMID:21495179, PMID:21834037, PMID:21850009, PMID:22087699, PMID:22256804, PMID:22317973, PMID:22499344, PMID:22683711, PMID:22726224, PMID:22926243, PMID:23093928, PMID:23096712, PMID:23406027, PMID:23429430, PMID:23751039, PMID:23884457, PMID:24006476, PMID:24033266, PMID:24129065, PMID:24169525, PMID:24224811, PMID:24390138, PMID:25157968, PMID:25326635, PMID:25741868, PMID:25914166, PMID:26619011, PMID:27195699, PMID:27589201, PMID:28027064, PMID:28139825, PMID:28390077, PMID:28492532, PMID:29073591, PMID:29493581, PMID:168335863 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hrg histidine-rich glycoprotein disease_progression ISO RGD PMID:21713765 RGD:11041886 NCBI chr11:81,621,274...81,639,938
Ensembl chr11:81,621,283...81,639,952
JBrowse link
G Jak1 Janus kinase 1 treatment ISO human cell line in a mouse model RGD PMID:29328487 RGD:13838743 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:2278970, PMID:3122217, PMID:12460918, PMID:15696205, PMID:16361624, PMID:16434492, PMID:16618717, PMID:18316791, PMID:18794081, PMID:19075190, PMID:19114683, PMID:19679400, PMID:20921462, PMID:20921465, PMID:21228335, PMID:22407852, PMID:22722830, PMID:23325582, PMID:25157968, PMID:26619011 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:11150980, PMID:12210337, PMID:12835555, PMID:14608654, PMID:16155195, PMID:16170316, PMID:16329078, PMID:16372351, PMID:16443854, PMID:16835863, PMID:16881968, PMID:16969868, PMID:17054105, PMID:17211612, PMID:17250658, PMID:17384584, PMID:17412879, PMID:17979197, PMID:18039947, PMID:18042262, PMID:18247425, PMID:18470943, PMID:18978862, PMID:19206176, PMID:19213030, PMID:19255327, PMID:19371735, PMID:19382114, PMID:19669404, PMID:19773371, PMID:20660566, PMID:20859122, PMID:20979192, PMID:21438134, PMID:21495179, PMID:21834037, PMID:21850009, PMID:22087699, PMID:22256804, PMID:22317973, PMID:22499344, PMID:22683711, PMID:22726224, PMID:22926243, PMID:23093928, PMID:23096712, PMID:23406027, PMID:23429430, PMID:23751039, PMID:23884457, PMID:24006476, PMID:24033266, PMID:24129065, PMID:24169525, PMID:24224811, PMID:24390138, PMID:25157968, PMID:25326635, PMID:25741868, PMID:25914166, PMID:26619011, PMID:27195699, PMID:27589201, PMID:28027064, PMID:28139825, PMID:28390077, PMID:28492532, PMID:29073591, PMID:29493581, PMID:168335863 NCBI chr 1:214,182,232...214,197,184
Ensembl chr 1:214,182,830...214,197,184
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 treatment
severity
ISO human tissue in a mouse model
protein:increased expression:pancreas (human)
RGD PMID:28849200, PMID:19513748 RGD:13838804, RGD:13838840 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:18042262, PMID:26619011 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Mapk1 mitogen activated protein kinase 1 severity ISO mRNA:increased expression:pancreas (human) RGD PMID:27919956 RGD:13451128 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk10 mitogen activated protein kinase 10 severity ISO DNA:SNP:intron: (rs2589506) (human) RGD PMID: RGD:13838853 NCBI chr14:8,079,955...8,371,508
Ensembl chr14:8,080,275...8,368,254
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO RGD PMID:22517435 RGD:14348976 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Med12 mediator complex subunit 12 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:26619011 NCBI chr  X:71,174,653...71,197,812
Ensembl chr  X:71,174,699...71,197,812
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:26619011 NCBI chr 6:38,222,554...38,228,419
Ensembl chr 6:38,222,555...38,228,379
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 severity ISO mRNA:increased expression:pancreas (human) RGD PMID:27919956 RGD:13451128 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Palld palladin, cytoskeletal associated protein ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:10454945, PMID:11474289, PMID:17194196, PMID:17415588, PMID:20436683, PMID:24033266, PMID:25741868, PMID:28492532 NCBI chr16:31,865,712...31,948,168 JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:15016963, PMID:15254419, PMID:15520168, PMID:15608678, PMID:15647370, PMID:15805248, PMID:15930273, PMID:16906227, PMID:16930767, PMID:17376864, PMID:17673550, PMID:18676830, PMID:18725974, PMID:19029981, PMID:19223544, PMID:19366826, PMID:19513541, PMID:19903786, PMID:20453058, PMID:20619739, PMID:21430269, PMID:21558396, PMID:21824802, PMID:22120714, PMID:22162582, PMID:22162589, PMID:22271473, PMID:22658544, PMID:22729222, PMID:22729223, PMID:22729224, PMID:23066039, PMID:23100325, PMID:23246288, PMID:23408298, PMID:23888070, PMID:24033266, PMID:24265155, PMID:24782230, PMID:25157968, PMID:25741868, PMID:26266975, PMID:26266985, PMID:26619011, PMID:26822237, PMID:27626068, PMID:27631024, PMID:28492532, PMID:29446767 NCBI chr 2:118,831,350...118,861,456
Ensembl chr 2:118,831,350...118,861,454
JBrowse link
G Plat plasminogen activator, tissue type ISO mRNA:increased expression:pancreas (human) RGD PMID:16733850 RGD:11541045 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:26619011, PMID:28492532 NCBI chr12:52,403,533...52,452,075
Ensembl chr12:52,403,529...52,452,040
JBrowse link
G Rac1 Rac family small GTPase 1 treatment ISO human cells in a mouse model RGD PMID:21037555 RGD:14392805 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase treatment ISO human cells in a mouse model RGD PMID:15014358 RGD:14392893 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Ralb RAS like proto-oncogene B treatment ISO human cells in a mouse model RGD PMID:17174914 RGD:14394417 NCBI chr13:35,494,716...35,531,503
Ensembl chr13:35,494,721...35,511,020
JBrowse link
G Ralbp1 ralA binding protein 1 treatment ISO human cells in a mouse model RGD PMID:22509328 RGD:13792559 NCBI chr 9:113,579,107...113,598,477
Ensembl chr 9:113,579,107...113,598,480
JBrowse link
G Rxra retinoid X receptor alpha ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:26619011 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Sf3b2 splicing factor 3b, subunit 2 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:26619011 NCBI chr 1:220,645,685...220,665,611
Ensembl chr 1:220,645,672...220,665,603
JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:6604412, PMID:8898652, PMID:9214508, PMID:9285566, PMID:9582123, PMID:9679244, PMID:9811934, PMID:10479724, PMID:10764709, PMID:10775259, PMID:10797267, PMID:11274206, PMID:11583957, PMID:12116240, PMID:12821112, PMID:14715079, PMID:15014009, PMID:15031030, PMID:15235019, PMID:16613914, PMID:17873119, PMID:17994767, PMID:18823382, PMID:20101697, PMID:22316667, PMID:22331366, PMID:25741868, PMID:26572829, PMID:26619011, PMID:26900293, PMID:27595937, PMID:28492532 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Smad7 SMAD family member 7 severity ISO human cell and construct in a mouse model RGD PMID:10498890 RGD:14394510 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:1349175, PMID:1359493, PMID:1565143, PMID:1565144, PMID:1569604, PMID:1591732, PMID:1631137, PMID:1644930, PMID:1673792, PMID:1683921, PMID:1686725, PMID:1737852, PMID:1915267, PMID:1918170, PMID:1978757, PMID:2046748, PMID:2113594, PMID:2259385, PMID:2826609, PMID:7565304, PMID:7651740, PMID:7707106, PMID:7732013, PMID:7750099, PMID:7783166, PMID:7881428, PMID:7887414, PMID:8023157, PMID:8062826, PMID:8080050, PMID:8099841, PMID:8118819, PMID:8164043, PMID:8242631, PMID:8336941, PMID:8364550, PMID:8401536, PMID:8423216, PMID:8425176, PMID:8479749, PMID:8527048, PMID:8550239, PMID:8633021, PMID:8688334, PMID:8718514, PMID:8825920, PMID:8829627, PMID:8869100, PMID:9020384, PMID:9049183, PMID:9096669, PMID:9157982, PMID:9218725, PMID:9242456, PMID:9268986, PMID:9290701, PMID:9364015, PMID:9407971, PMID:9472631, PMID:9525742, PMID:9546439, PMID:9569050, PMID:9572492, PMID:9598730, PMID:9627118, PMID:9632751, PMID:9635828, PMID:9662334, PMID:9667734, PMID:9825943, PMID:10064694, PMID:10229196, PMID:10411893, PMID:10432928, PMID:10519380, PMID:10567903, PMID:10589545, PMID:10616528, PMID:10713666, PMID:10761705, PMID:10797439, PMID:10864200, PMID:10871862, PMID:10914716, PMID:10922393, PMID:10949938, PMID:11051239, PMID:11051241, PMID:11139324, PMID:11180592, PMID:11313981, PMID:11370630, PMID:11429705, PMID:11479205, PMID:11590071, PMID:11593407, PMID:11782540, PMID:11793474, PMID:11896595, PMID:11920788, PMID:11920959, PMID:12007217, PMID:12034820, PMID:12406399, PMID:12509279, PMID:12672316, PMID:12695689, PMID:12700230, PMID:12702523, PMID:12726864, PMID:12792784, PMID:12826609, PMID:12885464, PMID:12901974, PMID:12909720, PMID:12917626, PMID:14559903, PMID:14584079, PMID:14673037, PMID:15004724, PMID:15017592, PMID:15037740, PMID:15077194, PMID:15138567, PMID:15161705, PMID:15381368, PMID:15390294, PMID:15541116, PMID:15580553, PMID:15607980, PMID:15607981, PMID:15722483, PMID:15781620, PMID:15825182, PMID:15850016, PMID:15925506, PMID:15951970, PMID:15977174, PMID:15982667, PMID:15993273, PMID:16209708, PMID:16258005, PMID:16312222, PMID:16322298, PMID:16337994, PMID:16401470, PMID:16474844, PMID:16489069, PMID:16494995, PMID:16508005, PMID:16551709, PMID:16633321, PMID:16682957, PMID:16736287, PMID:16778209, PMID:16793544, PMID:16818505, PMID:16827139, PMID:16861262, PMID:17015838, PMID:17311302, PMID:17390010, PMID:17401428, PMID:17417627, PMID:17427234, PMID:17530187, PMID:17540308, PMID:17541742, PMID:17567834, PMID:17572079, PMID:17606709, PMID:17636407, PMID:17724467, PMID:17875924, PMID:18208484, PMID:18307025, PMID:18453682, PMID:18511570, PMID:18555592, PMID:18628487, PMID:18685109, PMID:18978813, PMID:18989156, PMID:19012332, PMID:19101993, PMID:19147582, PMID:19171880, PMID:19336573, PMID:19367569, PMID:19378321, PMID:19405127, PMID:19462533, PMID:19468865, PMID:19556618, PMID:19681600, PMID:19850740, PMID:19913028, PMID:19930417, PMID:20013323, PMID:20028212, PMID:20113312, PMID:20127978, PMID:20128691, PMID:20195489, PMID:20234365, PMID:20308654, PMID:20364130, PMID:20407015, PMID:20505364, PMID:20506564, PMID:20516128, PMID:20522432, PMID:20593220, PMID:20693561, PMID:20805372, PMID:20878954, PMID:20972454, PMID:21056685, PMID:21059199, PMID:21115975, PMID:21159183, PMID:21187651, PMID:21232794, PMID:21305319, PMID:21319261, PMID:21343334, PMID:21356188, PMID:21470402, PMID:21483000, PMID:21484931, PMID:21514416, PMID:21519010, PMID:21522129, PMID:21535297, PMID:21552135, PMID:21601526, PMID:21626334, PMID:21674059, PMID:21747090, PMID:21760960, PMID:21760996, PMID:21761402, PMID:22006311, PMID:22052707, PMID:22090360, PMID:22109999, PMID:22110706, PMID:22114072, PMID:22186996, PMID:22198284, PMID:22233476, PMID:22265402, PMID:22427690, PMID:22540896, PMID:22672556, PMID:22710932, PMID:22713868, PMID:22768918, PMID:22811390, PMID:22844452, PMID:22847613, PMID:22862161, PMID:22866089, PMID:22887876, PMID:22899716, PMID:22915647, PMID:22919068, PMID:22923379, PMID:22983585, PMID:23031740, PMID:23124483, PMID:23161690, PMID:23165212, PMID:23172776, PMID:23175693, PMID:23246812, PMID:23259501, PMID:23263379, PMID:23264849, PMID:23265383, PMID:23315175, PMID:23340422, PMID:23355100, PMID:23406775, PMID:23538418, PMID:23625637, PMID:23630318, PMID:23667202, PMID:23713777, PMID:23792586, PMID:23894400, PMID:23950206, PMID:23967324, PMID:24033266, PMID:24038938, PMID:24076587, PMID:24122735, PMID:24256616, PMID:24381225, PMID:24384472, PMID:24395441, PMID:24487413, PMID:24501221, PMID:24549055, PMID:24573247, PMID:24590827, PMID:24603336, PMID:24641375, PMID:24651012, PMID:24651015, PMID:24677579, PMID:24702488, PMID:24728327, PMID:24744791, PMID:24763289, PMID:24766216, PMID:24810334, PMID:24835218, PMID:24940547, PMID:25119136, PMID:25123297, PMID:25157968, PMID:25293557, PMID:25294809, PMID:25339994, PMID:25428789, PMID:25433984, PMID:25503501, PMID:25504633, PMID:25525159, PMID:25584008, PMID:25584637, PMID:25619955, PMID:25634208, PMID:25669829, PMID:25691460, PMID:25741868, PMID:25757876, PMID:25787918, PMID:25896519, PMID:25925845, PMID:25927356, PMID:25945745, PMID:25952993, PMID:25980754, PMID:26014290, PMID:26022348, PMID:26024390, PMID:26205489, PMID:26225655, PMID:26230955, PMID:26270727, PMID:26425688, PMID:26467025, PMID:26497680, PMID:26534844, PMID:26554828, PMID:26556299, PMID:26585234, PMID:26619011, PMID:26659639, PMID:26681312, PMID:26781615, PMID:26786923, PMID:26787237, PMID:26822237, PMID:26845104, PMID:26878390, PMID:26911350, PMID:26976419, PMID:27022024, PMID:27077130, PMID:27149858, PMID:27179933, PMID:27189670, PMID:27276561, PMID:27328919, PMID:27374712, PMID:27458004, PMID:27463065, PMID:27489289, PMID:27493922, PMID:27501770, PMID:27523101, PMID:27533082, PMID:27616075, PMID:27621308, PMID:27622479, PMID:27680515, PMID:27683180, PMID:27714481, PMID:27724982, PMID:27730344, PMID:27895058, PMID:27959731, PMID:28152038, PMID:28279309, PMID:28369373, PMID:28453743, PMID:28472496, PMID:28476805, PMID:28477316, PMID:28492532, PMID:28724667, PMID:28802053, PMID:28861920, PMID:28915717, PMID:28975465, PMID:29025599, PMID:29070607, PMID:29126202, PMID:29324801, PMID:29416011, PMID:29470806, PMID:29478780, PMID:29489754, PMID:29752822, PMID:29753700, PMID:29979965, PMID:30076369, PMID:30087429, PMID:30128536, PMID:30216591, PMID:30224644, PMID:30297838, PMID:30306255, PMID:30311369, PMID:30327374, PMID:30352134, PMID:30450585, PMID:30630526, PMID:30709381, PMID:30720243, PMID:30840781 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G U2af1 U2 small nuclear RNA auxiliary factor 1 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:22158538, PMID:23029227, PMID:23861105, PMID:24498085, PMID:26619011 NCBI chr20:10,396,652...10,407,564
Ensembl chr20:10,396,621...10,407,554
JBrowse link
pancreatic cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4gnt alpha-1,4-N-acetylglucosaminyltransferase ISO mRNA:increased expression:blood, mononuclear cell RGD PMID:16441422 RGD:2325199 NCBI chr 8:107,856,853...107,866,438
Ensembl chr 8:107,859,366...107,865,789
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 ISO mRNA, protein:increased expression:pancreas RGD PMID:19020751 RGD:2317509 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 severity ISO mRNA:increased expression:pancreas RGD PMID:15688370 RGD:2325200 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 ISO mRNA:increased expression:pancreas RGD PMID:15688370 RGD:2325200 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19648918, PMID:26098869, PMID:20103627 RGD:2317511 NCBI chr 3:4,374,679...4,394,374
Ensembl chr 3:4,374,602...4,394,428
JBrowse link
G Ace angiotensin I converting enzyme ISO RGD PMID:19880966 RGD:2325208 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Acvr1 activin A receptor type 1 ISO RGD PMID:9714055 RGD:2317217 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Acvr1b activin A receptor type 1B ISO mRNA:increased expression:pancreas RGD PMID:9714055, PMID:11248065 RGD:2317217, RGD:1598735 NCBI chr 7:142,817,174...142,858,365
Ensembl chr 7:142,817,157...142,860,572
JBrowse link
G Acvr2a activin A receptor type 2A ISO RGD PMID:9714055 RGD:2317217 NCBI chr 3:32,947,901...33,034,598
Ensembl chr 3:32,947,378...33,034,282
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 ISO mRNA:increased expression:pancreas, epithelial cell RGD PMID:17465204 RGD:2325247 NCBI chr 2:188,661,831...188,672,337
Ensembl chr 2:188,661,699...188,672,247
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 ISO mRNA:increased expression:pancreas, epithelial cell RGD PMID:17465204 RGD:2325247 NCBI chr16:71,810,377...71,887,926
Ensembl chr16:71,810,377...71,887,926
JBrowse link
G Adgre5 adhesion G protein-coupled receptor E5 ISO protein:increased expression:pancreas RGD PMID:12428789 RGD:2317573 NCBI chr19:24,854,981...24,875,712
Ensembl chr19:24,855,299...24,875,137
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) ISO DNA:polymorphism: :p.R272Q (human) RGD PMID:19068087 RGD:2325313 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Adm adrenomedullin disease_progression ISO RGD PMID:17363587, PMID:16841081 RGD:2325317, RGD:2325318 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO protein:decreased expression:serum RGD PMID:20398646 RGD:2325643 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO mRNA:increased expression:pancreas RGD PMID:11916627 RGD:2325641 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Ahr aryl hydrocarbon receptor ISO mRNA:increased expression:pancreas
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:12203118, PMID:25826687, PMID:12203118 RGD:2325664 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akt1 AKT serine/threonine kinase 1 severity
treatment
ISO protein:increased phosphorylation:pancreas (human)
human cells in a mouse model
RGD PMID:20697673, PMID:11595724 RGD:13450953, RGD:13452388 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO RGD PMID:16847462, PMID:19506583 RGD:2290476, RGD:5490965 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alb albumin disease_progression ISO RGD PMID:18154768, PMID:20508721 RGD:2325678, RGD:2325675 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 ISO protein:decreased expression:pancreas RGD PMID:19216797 RGD:2325688 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member susceptibility ISO DNA:polymorphism: :p.E504K (human)
DNA:polymorphism (human)
RGD PMID:19068087, PMID:15714130 RGD:2325313, RGD:2325694 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO protein:increased expression:pancreas RGD PMID:12163367, PMID:12481414 RGD:2317524, RGD:2317523 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Ang angiogenin disease_progression ISO mRNA, protein:increased expression:pancreas, serum RGD PMID:8665497 RGD:2325716 NCBI chr15:28,022,926...28,028,636 JBrowse link
G Anxa1 annexin A1 ISO protein:increased expression:pancreas RGD PMID:19173988, PMID:17974280 RGD:2325722, RGD:2325723 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Anxa10 annexin A10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28369074 NCBI chr16:29,674,699...29,741,521
Ensembl chr16:29,674,793...29,741,465
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 ISO mRNA:increased expression:pancreas RGD PMID:17224646 RGD:2325739 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apc APC regulator of WNT signaling pathway ISO DNA:deletions (human)
DNA:mutation, loss of heterozygosity
RGD PMID:1423316, PMID:7478622 RGD:2317208, RGD:2317207 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Apoa1 apolipoprotein A1 ISO protein:decreased expression:serum
protein:increased expression:pancreas
RGD PMID:17312459, PMID:17332923 RGD:2325758, RGD:2325757 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoe apolipoprotein E IEP protein:increased expression:pancreas RGD PMID:16215274 RGD:2317552 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Arid1a AT-rich interaction domain 1A ISO RGD PMID:23355908 RGD:8694154 NCBI chr 5:151,904,687...151,977,973
Ensembl chr 5:151,904,684...151,977,636
JBrowse link
G Arid1b AT-rich interaction domain 1B ISO RGD PMID:23355908 RGD:8694154 NCBI chr 1:45,923,119...46,232,301
Ensembl chr 1:45,923,222...46,234,874
JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A ISO DNA:amplification (human) RGD PMID:19145645 RGD:2317557 NCBI chr12:11,272,609...11,294,084
Ensembl chr12:11,272,609...11,294,058
JBrowse link
G Artn artemin disease_progression ISO mRNA:increased expression:pancreas RGD PMID:20395845, PMID:19304517 RGD:2325815, RGD:2325817 NCBI chr 5:136,759,717...136,765,036
Ensembl chr 5:136,759,717...136,762,986
JBrowse link
G Atm ATM serine/threonine kinase susceptibility ISO DNA:SNP:intron:rs664677 (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:rs1801516(human)
DNA:SNP: :60G>A(human)
CTD PMID:26098866, PMID:26098869, PMID:16520463, PMID:19147782, PMID:18381943 RGD:2317367, RGD:2317363, RGD:2317234 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atr ATR serine/threonine kinase ISO DNA:SNP: :340C>T (human) RGD PMID:18381943 RGD:2317234 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Atrx ATRX, chromatin remodeler ISO CTD Direct Evidence: marker/mechanism CTD PMID:21252315 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878
JBrowse link
G Axl Axl receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26206560 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G B3galt5 Beta-1,3-galactosyltransferase 5 ISO mRNA:increased expression:pancreas RGD PMID:14555842 RGD:2317558 NCBI chr11:36,638,067...36,683,915
Ensembl chr11:36,634,662...36,683,672
JBrowse link
G Bad BCL2-associated agonist of cell death treatment ISO human cells in a mouse model RGD PMID:23523869 RGD:13451129 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bag3 BAG cochaperone 3 ISO mRNA:increased expression:pancreas RGD PMID:11513873 RGD:2325843 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Bag4 BAG cochaperone 4 ISO mRNA:increased expression:pancreas RGD PMID:10799310 RGD:2325852 NCBI chr16:71,057,709...71,075,874
Ensembl chr16:71,058,022...71,075,320
JBrowse link
G Bap1 Brca1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr16:7,336,685...7,345,511
Ensembl chr16:7,336,685...7,345,511
JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr19:43,932,543...43,967,452
Ensembl chr19:43,932,554...43,955,783
JBrowse link
G Bcl2l1 Bcl2-like 1 severity ISO human gene in a mouse model
CTD Direct Evidence: marker/mechanism
CTD PMID:16904634, PMID:17941720 RGD:11353794 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bid BH3 interacting domain death agonist ISO RGD PMID:15943879 RGD:2317560 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Boc BOC cell adhesion associated, oncogene regulated ISO RGD PMID:18772397 RGD:5490966 NCBI chr11:61,084,216...61,159,220
Ensembl chr11:61,083,757...61,158,838
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase disease_progression ISO human gene in a mouse model RGD PMID:18490924, PMID:22628411, PMID:22871572 RGD:13451537, RGD:13462040, RGD:13461863 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
G Brca1 BRCA1, DNA repair associated susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 4
ClinVar Annotator: match by term: Cancer of the pancreas
CTD
ClinVar
OMIM
PMID:7795652, PMID:7837387, PMID:7894493, PMID:8554067, PMID:8644702, PMID:8723683, PMID:8968102, PMID:9159158, PMID:9361038, PMID:9510469, PMID:9525870, PMID:9609997, PMID:9663595, PMID:10389907, PMID:10788334, PMID:10945975, PMID:11278247, PMID:11320250, PMID:11389159, PMID:11436123, PMID:11597388, PMID:12142080, PMID:12204006, PMID:12393792, PMID:12491499, PMID:12531920, PMID:12566964, PMID:12601471, PMID:12732733, PMID:12810666, PMID:12938098, PMID:14760071, PMID:14976165, PMID:15001988, PMID:15024741, PMID:15235020, PMID:15290653, PMID:15365993, PMID:15383404, PMID:15385441, PMID:15569676, PMID:15876480, PMID:16168118, PMID:16227521, PMID:16267036, PMID:16403807, PMID:16518693, PMID:16528604, PMID:16683254, PMID:16949048, PMID:17100994, PMID:17148771, PMID:17453335, PMID:17924331, PMID:18006916, PMID:18159056, PMID:18273839, PMID:18489799, PMID:18680205, PMID:18763032, PMID:18783588, PMID:18821011, PMID:19016756, PMID:19370767, PMID:19543972, PMID:19594371, PMID:19638463, PMID:19770520, PMID:19949876, PMID:19996028, PMID:20103620, PMID:20104584, PMID:20180014, PMID:20345474, PMID:20373018, PMID:20507347, PMID:20569256, PMID:20614009, PMID:20683152, PMID:21147198, PMID:21232165, PMID:21324516, PMID:21394826, PMID:21503673, PMID:21520273, PMID:21922593, PMID:21965345, PMID:21989927, PMID:21990134, PMID:21990165, PMID:22172724, PMID:22434525, PMID:22486713, PMID:22652532, PMID:22713736, PMID:22798144, PMID:22843421, PMID:23161852, PMID:23199084, PMID:23469205, PMID:23536787, PMID:23683081, PMID:23704879, PMID:23767878, PMID:23867111, PMID:24010542, PMID:24033266, PMID:24131973, PMID:24312913, PMID:24504028, PMID:24528374, PMID:24667779, PMID:24772314, PMID:24884479, PMID:25085752, PMID:25330149, PMID:25400221, PMID:25428789, PMID:25452441, PMID:25525159, PMID:25637381, PMID:25682074, PMID:25741868, PMID:25782689, PMID:25802882, PMID:25823446, PMID:25880076, PMID:25948282, PMID:26010302, PMID:26083025, PMID:26098869, PMID:26187060, PMID:26206375, PMID:26219728, PMID:26287763, PMID:26295337, PMID:26332594, PMID:26467025, PMID:26681312, PMID:26689913, PMID:26779294, PMID:26843898, PMID:26852130, PMID:27153395, PMID:27257965, PMID:27272900, PMID:27393621, PMID:27425403, PMID:27433846, PMID:27498913, PMID:27741520, PMID:27836010, PMID:27907908, PMID:27914478, PMID:27978560, PMID:28111427, PMID:28263838, PMID:28294317, PMID:28324225, PMID:28364669, PMID:28423363, PMID:28477318, PMID:28480178, PMID:28492532, PMID:28664449, PMID:28781887, PMID:29335924, PMID:29339979, PMID:29433453, PMID:29470806, PMID:29492181, PMID:29752822, PMID:29797126, PMID:29907814, PMID:29998185, PMID:30067863, PMID:30209399, PMID:30311386, PMID:30606148 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Brca2 BRCA2, DNA repair associated susceptibility ISO ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 2
ClinVar Annotator: match by term: Cancer of the pancreas
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 1
CTD Direct Evidence: marker/mechanism
DNA:mutations: :
OMIM
ClinVar
CTD
PMID:2073695, PMID:8075631, PMID:8524414, PMID:8673090, PMID:8673091, PMID:8673092, PMID:8758903, PMID:8841191, PMID:8841192, PMID:8896551, PMID:8988179, PMID:9042909, PMID:9145676, PMID:9150172, PMID:9667259, PMID:9758598, PMID:9792861, PMID:9971877, PMID:10417300, PMID:10570174, PMID:10644434, PMID:10978364, PMID:11149425, PMID:11179017, PMID:11307153, PMID:11400546, PMID:11595708, PMID:11802209, PMID:11948123, PMID:12142080, PMID:12204006, PMID:12473589, PMID:12670525, PMID:14559878, PMID:14576434, PMID:14647438, PMID:14973102, PMID:15117986, PMID:15131399, PMID:15145354, PMID:15168169, PMID:15382066, PMID:15695382, PMID:15994883, PMID:16168118, PMID:16455195, PMID:16683254, PMID:16825431, PMID:16905680, PMID:16949048, PMID:17063270, PMID:17100994, PMID:17148771, PMID:17591843, PMID:17657584, PMID:17899372, PMID:17925560, PMID:17972177, PMID:18465347, PMID:18489799, PMID:18607349, PMID:18627636, PMID:18779604, PMID:19016756, PMID:19043619, PMID:19188187, PMID:19491284, PMID:19499246, PMID:19656164, PMID:19863560, PMID:20104584, PMID:20215541, PMID:20216074, PMID:20301425, PMID:20380699, PMID:20694749, PMID:20736950, PMID:20858050, PMID:20887823, PMID:21218378, PMID:21324516, PMID:21465317, PMID:21613821, PMID:21952622, PMID:22006311, PMID:22009639, PMID:22126563, PMID:22217648, PMID:22430266, PMID:22703879, PMID:22798144, PMID:22970155, PMID:22995991, PMID:23096105, PMID:23199084, PMID:23265383, PMID:23318356, PMID:23341105, PMID:23469205, PMID:23593081, PMID:23621881, PMID:23658460, PMID:24033266, PMID:24156927, PMID:24470074, PMID:24489791, PMID:24556621, PMID:24728189, PMID:24728327, PMID:24884479, PMID:24916970, PMID:25011685, PMID:25452441, PMID:25682074, PMID:25741868, PMID:25782689, PMID:25802882, PMID:25863477, PMID:25980754, PMID:26026974, PMID:26098869, PMID:26187060, PMID:26221963, PMID:26287763, PMID:26295337, PMID:26360800, PMID:26402875, PMID:26440929, PMID:26467025, PMID:26530882, PMID:26541979, PMID:26681312, PMID:26709275, PMID:26757417, PMID:26852015, PMID:26867194, PMID:27124784, PMID:27157322, PMID:27257965, PMID:27425403, PMID:27469594, PMID:27658390, PMID:27701467, PMID:27732944, PMID:27741520, PMID:27831900, PMID:27882536, PMID:28008555, PMID:28111427, PMID:28179634, PMID:28222693, PMID:28277317, PMID:28283652, PMID:28294317, PMID:28324225, PMID:28351343, PMID:28419251, PMID:28477318, PMID:28492532, PMID:28541631, PMID:28724667, PMID:28767289, PMID:28993434, PMID:29020732, PMID:29084914, PMID:29088781, PMID:29161300, PMID:29192238, PMID:29240602, PMID:29288066, PMID:29321669, PMID:29339979, PMID:29368341, PMID:29394989, PMID:29433453, PMID:29446198, PMID:29492181, PMID:29681614, PMID:29752822, PMID:29907814, PMID:29988080, PMID:30039884, PMID:30078507, PMID:30287823, PMID:30415210, PMID:30702160, PMID:31131967, PMID:22187320 RGD:9068467 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B ISO protein:altered localization:pancreas RGD PMID:17242465 RGD:2326105 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G Cab39 calcium binding protein 39 disease_progression ISO RGD PMID:28197410 RGD:14398834 NCBI chr 9:92,834,327...92,895,778
Ensembl chr 9:92,834,357...92,895,778
JBrowse link
G Cacybp calcyclin binding protein disease_progression ISO mRNA, protein:increased expression:pancreas RGD PMID:18765951 RGD:2326146 NCBI chr13:77,948,771...77,959,089
Ensembl chr13:77,948,771...77,959,110
JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 disease_progression ISO mRNA, protein:increased expression:pancreas RGD PMID:19188911 RGD:2326238 NCBI chr 5:140,559,195...140,585,494
Ensembl chr 5:140,559,206...140,585,408
JBrowse link
G Capn10 calpain 10 susceptibility ISO DNA:SNP:intron:rs3792267 (human) RGD PMID:20178008 RGD:4107073 NCBI chr 9:100,104,000...100,112,833
Ensembl chr 9:100,104,000...100,112,832
JBrowse link
G Casp8 caspase 8 susceptibility ISO DNA:SNP: :rs1045485 (human)
DNA:deletion, insertion:promoter (human)
RGD PMID:19843670, PMID:18483392 RGD:2317230, RGD:2315744 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 susceptibility
treatment
ISO DNA:snp:promoter:g.-1263A>G (human) RGD PMID:20357690, PMID:19209030 RGD:13451540, RGD:13462046 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase disease_progression ISO protein:decreased expression:pancreas RGD PMID:12499913 RGD:2317410 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbr4 carbonyl reductase 4 ISO ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 1 ClinVar PMID:25741868, PMID:28492532 NCBI chr16:31,944,328...31,972,553
Ensembl chr16:31,956,753...31,972,507
JBrowse link
G Cckar cholecystokinin A receptor IEP
ISO
mRNA:increased expression:pancreas RGD PMID:8222074, PMID:10457335 RGD:4110822, RGD:4110817 NCBI chr14:59,610,939...59,619,786
Ensembl chr14:59,611,434...59,619,783
JBrowse link
G Cckbr cholecystokinin B receptor disease_progression
susceptibility
IEP
IDA
ISO
mRNA:increased expression:pancreas RGD PMID:8302799, PMID:8222074, PMID:1458479, PMID:15688412 RGD:4110823, RGD:4110822, RGD:4110821, RGD:4110829 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30603057, PMID:10225458 RGD:7483623 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO RGD PMID:19155524 RGD:2317567 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccnd1 cyclin D1 disease_progression
treatment
ISO human cells in a mouse model
mRNA, protein:increased expression:pancreas (mouse)
RGD PMID:22722256, PMID:11159909, PMID:17541034 RGD:13451541, RGD:13452385, RGD:13462059 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 ISO protein:increased expression:pancreas RGD PMID:12761880 RGD:2317610 NCBI chr 8:122,530,152...122,535,959
Ensembl chr 8:122,530,624...122,532,070
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 ISO RGD PMID:19155524 RGD:2317567 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cd24 CD24 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:28369074 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Cd44 CD44 molecule (Indian blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:17446842 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cdc42 cell division cycle 42 severity ISO mRNA, protein:increased expression:pancreas (human) RGD PMID:28181096 RGD:13452244 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18223216 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdk4 cyclin-dependent kinase 4 susceptibility
disease_progression
ISO
IEP
protein:increased expression:islet of Langerhans (human)
protein:increased expression:islet of Langerhans, nucleus (rat)
protein:increased expression:pancreas (mouse)
RGD PMID:22761470, PMID:24531709, PMID:22477723, PMID:11159909 RGD:13452384, RGD:13452387, RGD:13452386, RGD:13452385 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO DNA:mutations:exon
CTD Direct Evidence: marker/mechanism
CTD PMID:10627132, PMID:26098869, PMID:18772397 RGD:5490966 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:20876774 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Cftr CF transmembrane conductance regulator no_association
onset
ISO RGD PMID:17072959, PMID:16227367 RGD:2317157, RGD:2317156 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Chek1 checkpoint kinase 1 disease_progression ISO DNA:SNP: :35G>A (human) RGD PMID:18381943 RGD:2317234 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Cldn4 claudin 4 ISO RGD PMID:19555390, PMID:19793693 RGD:2317583, RGD:2317580 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Clptm1 CLPTM1 regulator of GABA type A receptor forward trafficking ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr 1:80,549,051...80,580,665
Ensembl chr 1:80,549,043...80,580,662
JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16818650 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16818650 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18223216 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cycs cytochrome c, somatic ISO RGD PMID:11920648 RGD:2317614 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 susceptibility ISO DNA:transition:5' utr:-34T>C rs743572 (human) RGD PMID:19642097 RGD:2317618 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 EXP CTD Direct Evidence: therapeutic CTD PMID:10026857, PMID:10326030, PMID:10415878, PMID:11332152, PMID:11377651, PMID:12042985, PMID:12649565, PMID:12698877 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Daxx death-domain associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21252315 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:pancreas
CTD PMID:17443278, PMID:19020767, PMID:18309485, PMID:20072795 RGD:2317630, RGD:2317629 NCBI chr 2:221,823,692...222,694,627
Ensembl chr 2:221,823,687...222,694,627
JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:31838052 NCBI chr11:34,858,339...34,958,733
Ensembl chr11:34,865,532...34,956,536
JBrowse link
G E2f1 E2F transcription factor 1 treatment IEP RGD PMID:28344092 RGD:13838737 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208748 NCBI chr14:113,202,382...113,294,993
Ensembl chr14:113,202,419...113,295,014
JBrowse link
G Egf epidermal growth factor disease_progression ISO protein:increased expression:pancreas RGD PMID:1347773, PMID:19506583 RGD:2317650, RGD:5490965 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27720938, PMID:17452677, PMID:19506583 RGD:5131631, RGD:5490965 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 ISO protein:increased expression:serum (human) RGD PMID:15796914 RGD:10045549 NCBI chr10:108,415,201...108,425,195
Ensembl chr10:108,415,202...108,425,206
JBrowse link
G Epcam epithelial cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:17446842 NCBI chr 6:11,282,194...11,308,870
Ensembl chr 6:11,281,964...11,298,216
JBrowse link
G Epha3 Eph receptor A3 ISO RGD PMID:14670182 RGD:2317720 NCBI chr11:421,253...783,037
Ensembl chr11:421,135...782,954
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit susceptibility ISO DNA:snp:3' utr:c.*197G>T (rs3212986) (human) RGD PMID:27050953 RGD:13207426 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit treatment ISO pancreatic adenocarcinoma;DNA:SNPs: :rs1799793,rs1052555(human)
DNA,protein:SNPs:exons:rs1799793,rs1052559(human)
RGD PMID:18544627, PMID:21404106, PMID:16458430 RGD:2317223, RGD:11252206, RGD:2317228 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit ISO pancreatic adenocarcinoma;DNA:SNP: :rs1800067(human) RGD PMID:18544627 RGD:2317223 NCBI chr10:2,010,140...2,037,953
Ensembl chr10:2,010,648...2,037,891
JBrowse link
G Etaa1 ETAA1 activator of ATR kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr14:102,290,655...102,293,674
Ensembl chr14:102,290,418...102,293,677
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit IEP protein:increased expression:pancreas RGD PMID:22222375 RGD:9588324 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G Fanca FA complementation group A ISO DNA,Protein:polymorphisms:exons:c.377C>G, c.661A>G (human) RGD PMID:15591268 RGD:2317735 NCBI chr19:56,067,548...56,126,075
Ensembl chr19:56,067,548...56,126,063
JBrowse link
G Fancc FA complementation group C ISO DNA:nonsense mutation (human) RGD PMID:16243825, PMID:15695377 RGD:2317238, RGD:2317239 NCBI chr17:826,512...955,703
Ensembl chr17:833,509...955,615
JBrowse link
G Fancg FA complementation group G ISO RGD PMID:16243825 RGD:2317238 NCBI chr 5:58,448,060...58,456,416
Ensembl chr 5:58,448,822...58,455,819
JBrowse link
G Faslg Fas ligand severity
resistance
ISO DNA:polymorphism:promoter:-844>>T (human) RGD PMID:11115536, PMID:12370548, PMID:18483392 RGD:2317745, RGD:2317744, RGD:2315744 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fgf13 fibroblast growth factor 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19917848 NCBI chr  X:142,053,648...142,589,274
Ensembl chr  X:142,053,654...142,248,369
JBrowse link
G Fgf2 fibroblast growth factor 2 severity ISO mRNA:increased expression:pancreas
protein:increased expression:bile
RGD PMID:9293890, PMID:11562741, PMID:11478488, PMID:12670449 RGD:2317762, RGD:2317760, RGD:2317765, RGD:2317759 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand IMP RGD PMID:16528542 RGD:11049499 NCBI chr 1:101,126,006...101,131,413
Ensembl chr 1:101,124,479...101,131,413
JBrowse link
G Foxp1 forkhead box P1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25485836 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G Fscn1 fascin actin-bundling protein 1 severity ISO protein:increased expression:pancreas RGD PMID:17696949 RGD:2317785 NCBI chr12:13,655,459...13,668,595
Ensembl chr12:13,656,554...13,668,515
JBrowse link
G Fxyd3 FXYD domain-containing ion transport regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16003754 NCBI chr 1:89,502,561...89,510,146
Ensembl chr 1:89,502,562...89,509,343
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha ISO CTD Direct Evidence: therapeutic CTD PMID:19003803 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gdnf glial cell derived neurotrophic factor severity ISO RGD PMID:18652760 RGD:2324925 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gli1 GLI family zinc finger 1 ISO RGD PMID:21186299, PMID:18772397 RGD:5491005, RGD:5490966 NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338
JBrowse link
G Gli3 GLI family zinc finger 3 ISO RGD PMID:18772397 RGD:5490966 NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036
JBrowse link
G Gnas GNAS complex locus ISO RGD PMID:12771991 RGD:2317256 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gstp1 glutathione S-transferase pi 1 susceptibility ISO DNA:SNP:cds:p.I105V (rs1695) (human) RGD PMID:19536452, PMID:19786118 RGD:2317805, RGD:2317804 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hgf hepatocyte growth factor ISO protein:increased expression:serum RGD PMID:20017454 RGD:2317895 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16628086 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hs3st2 heparan sulfate-glucosamine 3-sulfotransferase 2 ISO DNA:hypermethylation:promoter (human) RGD PMID:12527896 RGD:2317633 NCBI chr 1:191,344,979...191,474,143
Ensembl chr 1:191,344,979...191,474,142
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 disease_progression ISO RGD PMID:21833720 RGD:10402768 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO mRNA, protein:increased expression:pancreas RGD PMID:11815996 RGD:2325165 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma ISO protein:increased expression:plasma RGD PMID:19152246 RGD:2317258 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 susceptibility ISO DNA:polymorphism (human) RGD PMID:19064563 RGD:2306689 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor ISO RGD PMID:14559833, PMID:19732452, PMID:19885860 RGD:2317651, RGD:2317642, RGD:2317640 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Il10 interleukin 10 disease_progression
susceptibility
ISO protein:increased expression:serum
DNA:polymorphism: :-1082G>A (human)
RGD PMID:17235586, PMID:30304975, PMID:30610790, PMID:19250218 RGD:2317655, RGD:14975257, RGD:14975253, RGD:2317653 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il13 interleukin 13 disease_progression ISO protein:increased expression:pancreas RGD PMID:18758789, PMID:12808442 RGD:2317669, RGD:2317670 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 treatment ISO RGD PMID:11748276 RGD:8549514 NCBI chr  X:118,443,955...118,514,716
Ensembl chr  X:118,443,823...118,513,061
JBrowse link
G Il1a interleukin 1 alpha ISO RGD PMID:7787209 RGD:2311069 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta susceptibility ISO DNA:polymorphisms:promoter:-511C>T, -31T>C (human)
protein:increased expression:serum (human)
RGD PMID:19251436, PMID:7787209 RGD:2317215, RGD:2311069 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 treatment ISO RGD PMID:9080118 RGD:8663440 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il24 interleukin 24 ISO CTD Direct Evidence: therapeutic CTD PMID:15580305 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Il3 interleukin 3 ISO protein:increased expression:serum RGD PMID:15843207 RGD:2317663 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il4 interleukin 4 disease_progression ISO protein:increased expression:blood RGD PMID:19957810, PMID:12097255, PMID:10404069 RGD:2317261, RGD:2317265, RGD:2317267 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4r interleukin 4 receptor disease_progression ISO protein:increased expression:pancreas RGD PMID:18758789 RGD:2317669 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Il6 interleukin 6 disease_progression ISO RGD PMID:30610790, PMID:30304975 RGD:14975253, RGD:14975257 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ilk integrin-linked kinase ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189
JBrowse link
G Ins2 insulin 2 susceptibility
disease_progression
ISO associated with Diabetes Mellitus
DNA:Polymorphism:promoter:-23 HphI (human)
associated with Diabetes Mellitus, Non-Insulin-Depend
RGD PMID:19375425, PMID:19152242, PMID:19628082, PMID:19572116 RGD:2317250, RGD:2317253, RGD:2317245, RGD:2317247 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Itga11 integrin subunit alpha 11 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 8:67,566,874...67,683,973
Ensembl chr 8:67,615,635...67,683,973
JBrowse link
G Itga4 integrin subunit alpha 4 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 3:66,178,745...66,265,547
Ensembl chr 3:66,193,059...66,263,960
JBrowse link
G Itga9 integrin subunit alpha 9 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 8:127,271,029...127,576,709
Ensembl chr 8:127,271,289...127,572,988
JBrowse link
G Kdr kinase insert domain receptor ISO CTD Direct Evidence: therapeutic CTD PMID:12385004, PMID:19930156 RGD:5684397 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Klf5 Kruppel-like factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921
JBrowse link
G Kras KRAS proto-oncogene, GTPase disease_progression ISO ClinVar Annotator: match by term: Pancreatic cancer
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:2278970, PMID:3122217, PMID:7773929, PMID:8439212, PMID:12460918, PMID:14520703, PMID:15696205, PMID:15842656, PMID:16361624, PMID:16434492, PMID:16618717, PMID:17332249, PMID:17384584, PMID:17704260, PMID:17910045, PMID:18316791, PMID:18794081, PMID:19018267, PMID:19029981, PMID:19047918, PMID:19075190, PMID:19114683, PMID:19255327, PMID:19358724, PMID:19424582, PMID:19679400, PMID:19773371, PMID:19881948, PMID:20609353, PMID:20805368, PMID:20921462, PMID:20921465, PMID:20949522, PMID:21079152, PMID:21169357, PMID:21228335, PMID:21398618, PMID:21699781, PMID:21975775, PMID:22025163, PMID:22235099, PMID:22407852, PMID:22499344, PMID:22683711, PMID:22897852, PMID:23014527, PMID:23096712, PMID:23406027, PMID:24033266, PMID:24694877, PMID:25044103, PMID:25157968, PMID:25695684, PMID:25961927, PMID:26372703, PMID:26390243, PMID:28492532, PMID:29298116, PMID:31891627, PMID:11115351, PMID:18772397, PMID:19506583 RGD:1581761, RGD:5490966, RGD:5490965 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G L1cam L1 cell adhesion molecule treatment ISO RGD PMID:22095073 RGD:11570404 NCBI chr  X:156,901,244...156,928,064
Ensembl chr  X:156,909,913...156,928,057
JBrowse link
G Ldha lactate dehydrogenase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:29384525 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Lig3 DNA ligase 3 resistance ISO DNA:SNP:intron:rs 2074522 (human) RGD PMID:19147782 RGD:2317363 NCBI chr10:70,134,734...70,158,051
Ensembl chr10:70,134,729...70,158,055
JBrowse link
G Lig4 DNA ligase 4 susceptibility ISO associated with Diabetes Mellitus;DNA:polymorphism: :54C>T (human) RGD PMID:19147782 RGD:2317363 NCBI chr16:85,331,771...85,339,496
Ensembl chr16:85,331,866...85,337,769
JBrowse link
G Lpl lipoprotein lipase ISO ClinVar Annotator: match by term: Pancreatic tumor ClinVar PMID:1598907, PMID:30311386 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrp2 LDL receptor related protein 2 ISO RGD PMID:18772397 RGD:5490966 NCBI chr 3:55,665,153...55,822,484
Ensembl chr 3:55,665,145...55,822,551
JBrowse link
G Lum lumican disease_progression ISO DNA:SNP: :rs2268578 (human) RGD PMID:19843670, PMID:17671699 RGD:2317230, RGD:2317682 NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
JBrowse link
G Ly6e lymphocyte antigen 6 family member E ISO CTD Direct Evidence: marker/mechanism CTD PMID:17446842 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor no_association ISO DNA:point mutations, deletions:cds:multiple (human)
DNA:polymorphisms: :multiple (human)
RGD PMID:9174057, PMID:17072959 RGD:2325804, RGD:2317157 NCBI chr 8:115,623,175...115,626,408
Ensembl chr 8:115,623,178...115,626,380
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 ISO RGD PMID:18772397 RGD:5490966 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657
JBrowse link
G Men1 menin 1 ISO associated with Neuroendocrine Tumors; protein:increased expression:multiple organs
CTD Direct Evidence: marker/mechanism
CTD PMID:17961653, PMID:21252315, PMID:17278096 RGD:2317340 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase severity IEP
ISO
protein:increased expression:pancreas (rat)
mRNA:increased expression:pancreas (human)
RGD PMID:9211490, PMID:19506583, PMID:15448002 RGD:2317613, RGD:5490965, RGD:2317235 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mgat4a alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A ISO RGD PMID:16434023 RGD:2317701 NCBI chr 9:44,033,433...44,126,946
Ensembl chr 9:44,033,436...44,126,919
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO protein:decreased expression:neuroendocrine tumor (human) RGD PMID:19118063 RGD:2317628 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mir107 microRNA 107 severity ISO RGD PMID:28720759 RGD:14975279 NCBI chr 1:253,128,250...253,128,336
Ensembl chr 1:253,128,250...253,128,336
JBrowse link
G Mki67 marker of proliferation Ki-67 disease_progression ISO protein:increased expression:pancreas RGD PMID:20137856, PMID:20350215 RGD:2317704, RGD:2317703 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO mRNA:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
protein:increased activity:pancreatic juice
CTD PMID:30603057, PMID:7635566, PMID:11961486 RGD:2325766, RGD:2325752 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:pancreas
protein:increased expression:serum
CTD PMID:22952646, PMID:18445772, PMID:7635566, PMID:19629003, PMID:18030366 RGD:2325849, RGD:2325766, RGD:2325831, RGD:2325854 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase resistance ISO DNA:polymorphism:promoter:-463G>A (human) RGD PMID:18205184 RGD:2317406 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Msln mesothelin ISO CTD Direct Evidence: marker/mechanism
associated with Pancreatic Disease; protein:increased expression:pancreas
CTD PMID:11751476, PMID:19843662, PMID:18281514, PMID:17785569, PMID:17019794 RGD:2326052, RGD:2326056, RGD:2326062, RGD:2326060 NCBI chr10:15,119,700...15,129,129
Ensembl chr10:15,119,663...15,125,408
JBrowse link
G Mtap methylthioadenosine phosphorylase ISO DNA, protein:deletion, decreased activity:pancreas: RGD PMID:15534104 RGD:2317952 NCBI chr 5:107,711,077...107,777,530
Ensembl chr 5:107,711,077...107,777,530
JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO DNA:polymorphism: :677C>T (human) RGD PMID:16737574 RGD:2317120 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:23149918 RGD:10040959 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase susceptibility
no_association
ISO DNA:Polymorphism: :rs1805087 (human) RGD PMID:18843018, PMID:16737574 RGD:2317118, RGD:2317120 NCBI chr17:66,210,444...66,295,014
Ensembl chr17:66,210,461...66,295,014
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:polymorphism: :66A>G (human)
DNA:SNPs:intron, exon:rs162049, p.H595Y (rs10380) (human)
RGD PMID:18843018, PMID:18515090 RGD:2317118, RGD:2325772 NCBI chr 1:37,743,089...37,774,485
Ensembl chr 1:37,743,147...37,774,015
JBrowse link
G Muc1 mucin 1, cell surface associated disease_progression ISO protein:increased expression:pancreas
protein:increased secretion:bile
RGD PMID:14654947, PMID:18039393, PMID:18383873, PMID:19129927, PMID:19055478, PMID:18575732 RGD:2317984, RGD:2324639, RGD:2324637, RGD:2317987, RGD:2324622, RGD:2324635 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Muc16 mucin 16, cell surface associated ISO protein:increased expression:serum RGD PMID:19377061 RGD:2325129 NCBI chr 8:18,438,838...18,639,777 JBrowse link
G Muc4 mucin 4, cell surface associated disease_progression ISO mRNA:increased expression:peripheral blood mononuclear cell
protein:increased expression:pancreas
mRNA:increased expression:pancreas
RGD PMID:16274046, PMID:17595659, PMID:20303649, PMID:11751498, PMID:17406026 RGD:2324931, RGD:2324922, RGD:2324914, RGD:2324891, RGD:2324923 NCBI chr11:71,242,973...71,285,217
Ensembl chr11:71,243,334...71,284,939
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming ISO protein:increased glycosylation:serum
protein:increased expression:pancreas
RGD PMID:19377061, PMID:14654947 RGD:2325129, RGD:2317984 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Muc6 mucin 6, oligomeric mucus/gel-forming ISO protein:increased expression: : RGD PMID:10209489 RGD:2325167 NCBI chr 1:214,608,453...214,630,524
Ensembl chr 1:214,608,704...214,629,938
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25961927, PMID:22024988 RGD:7240699 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 ISO human gene in a mouse model RGD PMID:25071868 RGD:9590074 NCBI chr 7:54,213,305...54,237,880
Ensembl chr 7:54,213,319...54,236,625
JBrowse link
G Nat1 N-acetyltransferase 1 susceptibility ISO DNA:polymorphism (human)
DNA:polymorphisms,haplotype: :
RGD PMID:18006927, PMID:18006927, PMID:18499698 RGD:2317170, RGD:2317170, RGD:2317168 NCBI chr16:23,970,742...23,991,573
Ensembl chr16:23,970,743...23,991,573
JBrowse link
G Nat2 N-acetyltransferase 2 susceptibility ISO DNA:polymorphism (human) RGD PMID:18027363 RGD:2317169 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link
G Ncam1 neural cell adhesion molecule 1 severity
disease_progression
ISO RGD PMID:10374842, PMID:11249065 RGD:2326075, RGD:2326074 NCBI chr 8:53,836,797...54,134,881
Ensembl chr 8:53,839,098...53,901,358
JBrowse link
G Nfkbia NFKB inhibitor alpha ISO CTD Direct Evidence: therapeutic CTD PMID:15861417 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Ngfr nerve growth factor receptor severity ISO mRNA:increased expression:tumor:associated with longer overall survival (human) RGD PMID:16704535 RGD:5508229 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nos2 nitric oxide synthase 2 disease_progression ISO protein:increased expression:pancreas RGD PMID:11196200, PMID:11687972, PMID:15165031 RGD:2325262, RGD:2325257, RGD:2325248 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Notch1 notch receptor 1 disease_progression ISO protein:increased expression:pancreas RGD PMID:17297654 RGD:2325328 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20660371 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20101243, PMID:26098869 NCBI chr13:53,750,470...53,870,288
Ensembl chr13:53,750,473...53,870,428
JBrowse link
G Nrp1 neuropilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15956974 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 severity ISO mRNA:increased expression:tumor:associated with increased tumor aggressiveness (human) RGD PMID:16704535 RGD:5508229 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 ISO DNA:mutation:pancreas RGD PMID:16941478 RGD:2325656 NCBI chr 1:139,890,537...140,262,503
Ensembl chr 1:139,890,560...140,262,503
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex treatment ISO mRNA:increased expression:pancreas RGD PMID:26045769, PMID:25370920 RGD:11058437, RGD:28867232 NCBI chr13:87,818,456...87,847,223
Ensembl chr13:87,818,391...87,847,263
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase disease_progression ISO DNA:polymorphism: :2657G>A (human)
DNA:polymorphism: :rs1052133 (human)
RGD PMID:17230526, PMID:18559563 RGD:2317132, RGD:2317130 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Palb2 partner and localizer of BRCA2 susceptibility ISO DNA:nonsense mutations:exon:172_175del, 3116del, 3256C>T (human)
ClinVar Annotator: match by term: Cancer of the pancreas
ClinVar Annotator: match by term: Pancreatic cancer 3
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
PMID:17200668, PMID:17200671, PMID:18302019, PMID:19264984, PMID:20122277, PMID:20412113, PMID:20582465, PMID:20589654, PMID:21165770, PMID:21285249, PMID:21365267, PMID:23561644, PMID:23977390, PMID:24033266, PMID:24061862, PMID:24136930, PMID:24415441, PMID:24448499, PMID:24556926, PMID:24728327, PMID:25099575, PMID:25186627, PMID:25330149, PMID:25356972, PMID:25452441, PMID:25575445, PMID:25741868, PMID:25959805, PMID:25980754, PMID:26083025, PMID:26098869, PMID:26270727, PMID:26283626, PMID:26315354, PMID:26411315, PMID:26467025, PMID:26489409, PMID:26564480, PMID:26681312, PMID:26720728, PMID:26845104, PMID:27038244, PMID:27099641, PMID:27106063, PMID:27624329, PMID:27783279, PMID:28158555, PMID:28279176, PMID:28492532, PMID:28724667, PMID:28779002, PMID:29752822, PMID:29909963, PMID:30287823, PMID:30311386, PMID:30638972, PMID:31843900, PMID:32566746, PMID:19264984 RGD:2325776 NCBI chr 1:192,064,586...192,088,547
Ensembl chr 1:192,064,589...192,088,520
JBrowse link
G Palld palladin, cytoskeletal associated protein susceptibility ISO DNA, mRNA:missense mutation, increased expression:pancreas:p.P239S (human)
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 1
CTD Direct Evidence: marker/mechanism
protein:increased expression, alternative form:pancreas, fibroblast
ClinVar
CTD
OMIM
PMID:10454945, PMID:11474289, PMID:17194196, PMID:17415588, PMID:20436683, PMID:24033266, PMID:25741868, PMID:28492532, PMID:17194196, PMID:20436683 RGD:2325782, RGD:2325779 NCBI chr16:31,865,712...31,948,168 JBrowse link
G Pbrm1 polybromo 1 ISO RGD PMID:23355908 RGD:8694154 NCBI chr16:7,103,714...7,202,899
Ensembl chr16:7,103,998...7,200,362
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha ISO mRNA:increased expression:pancreas RGD PMID:7665222, PMID:14695158 RGD:2324851, RGD:2324850 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19077462, PMID:25086665, PMID:26098869 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213
JBrowse link
G Pfn1 profilin 1 ISO RGD PMID:16215274 RGD:2317552 NCBI chr10:57,273,003...57,275,708
Ensembl chr10:57,273,005...57,275,708
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10467400 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component ISO ClinVar Annotator: match by term: Pancreatic tumor ClinVar PMID:30311386 NCBI chr 9:53,120,656...53,206,520
Ensembl chr 9:53,120,656...53,206,516
JBrowse link
G Polb DNA polymerase beta disease_progression ISO DNA:polymorphisms: :165A>G, 2133T>C (human) RGD PMID:17230526 RGD:2317132 NCBI chr16:74,237,001...74,260,272
Ensembl chr16:74,237,001...74,260,271
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta disease_progression ISO RGD PMID:17652168, PMID:17652168 RGD:2324872, RGD:2324872 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma susceptibility ISO DNA:polymorphism: :p.P12A (human)
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:11034103, PMID:11741176, PMID:19436234, PMID:19152448 RGD:2317460, RGD:2317462 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptch1 patched 1 ISO protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
CTD PMID:19077462, PMID:19396459 RGD:2324910 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873
JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:19917848, PMID:19506583 RGD:5490965 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 susceptibility ISO mRNA, protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :-1195A > G, -765G > C (human)
DNA:polymorphisms: :-1195A>A ,-765G>C (human)
CTD PMID:10485483, PMID:10657949, PMID:15705899, PMID:16820089, PMID:19820419, PMID:19062735, PMID:20216081, PMID:19422084 RGD:2317179, RGD:5135527, RGD:2317175, RGD:2317184 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pthlh parathyroid hormone-like hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:17625444 NCBI chr 4:181,663,425...181,674,181 JBrowse link
G Rabl3 RAB, member of RAS oncogene family-like 3 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 5
CTD
OMIM
ClinVar
PMID:31406347 NCBI chr11:66,049,635...66,078,669
Ensembl chr11:66,049,635...66,078,669
JBrowse link
G Rad51 RAD51 recombinase IEP protein:increased expression:pancreas (rat) RGD PMID:20197614 RGD:9831172 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Rad54l RAD54 like ISO DNA:SNP:exon:rs1048771 (human) RGD PMID:16540687 RGD:2317365 NCBI chr 5:134,948,511...134,978,125
Ensembl chr 5:134,948,512...134,978,125
JBrowse link
G Rap1gap Rap1 GTPase-activating protein ISO mRNA:decreased expression:pancreas (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:22614916, PMID:16424023 RGD:9835037 NCBI chr 5:156,008,868...156,074,350
Ensembl chr 5:156,026,911...156,074,395
JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21699781 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Recql RecQ like helicase ISO DNA:SNPs:introns
DNA:SNP:3'utr:rs13035 (human)
RGD PMID:18422747, PMID:19768149, PMID:16540687 RGD:2317370, RGD:2317369, RGD:2317365 NCBI chr 4:176,581,892...176,606,520
Ensembl chr 4:176,581,897...176,606,382
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO RGD PMID:9918209 RGD:2298892 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ret ret proto-oncogene disease_progression ISO protein:increased expression:pancreas RGD PMID:16269310 RGD:2324926 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 ISO RGD PMID:19568409 RGD:2324950 NCBI chr 6:43,884,627...43,890,818
Ensembl chr 6:43,884,678...43,889,515
JBrowse link
G Runx3 RUNX family transcription factor 3 disease_progression ISO DNA:hypermethylation, loss of heterozygosity (human) RGD PMID:18475302 RGD:2324956 NCBI chr 5:153,507,093...153,531,137
Ensembl chr 5:153,507,093...153,531,137
JBrowse link
G Rxra retinoid X receptor alpha ISO RGD PMID:19152448 RGD:2317462 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Sel1l SEL1L adaptor subunit of ERAD E3 ubiquitin ligase ISO RGD PMID:14508516 RGD:2317190 NCBI chr 6:115,572,683...115,616,904
Ensembl chr 6:115,572,649...115,616,859
JBrowse link
G Serpina1 serpin family A member 1 disease_progression ISO RGD PMID:2323846 RGD:2324960 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Shh sonic hedgehog signaling molecule ISO RGD PMID:19506583 RGD:5490965 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Slc29a1 solute carrier family 29 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18728667 NCBI chr 9:17,784,468...17,799,008
Ensembl chr 9:17,784,468...17,799,005
JBrowse link
G Smad2 SMAD family member 2 ISO mRNA:increased expression:pancreas (human) RGD PMID:10505717 RGD:14394490 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad3 SMAD family member 3 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Pancreatic cancer
DNA:mutations:exon
OMIM
ClinVar
PMID:8898652, PMID:9679244, PMID:9811934, PMID:10479724, PMID:10764709, PMID:10775259, PMID:10797267, PMID:11274206, PMID:12821112, PMID:14715079, PMID:15014009, PMID:15031030, PMID:15235019, PMID:16613914, PMID:17873119, PMID:17994767, PMID:20101697, PMID:22331366, PMID:25741868, PMID:26619011, PMID:27595937, PMID:27978560, PMID:28135145, PMID:28492532, PMID:18772397 RGD:5490966 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Smad7 SMAD family member 7 ISO mRNA:increased expression:pancreas (human) RGD PMID:10498890 RGD:14394510 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO RGD PMID:23355908 RGD:8694154 NCBI chr 8:22,648,323...22,739,468
Ensembl chr 8:22,648,323...22,739,468
JBrowse link
G Smo smoothened, frizzled class receptor ISO protein:increased expression:pancreas RGD PMID:19460966, PMID:19396459 RGD:2324978, RGD:2324910 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770
JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 ISO RGD PMID:17726579 RGD:2302550 NCBI chr12:11,433,815...11,526,465
Ensembl chr12:11,407,213...11,526,465
JBrowse link
G Sncg synuclein, gamma ISO RGD PMID:15221989 RGD:6478801 NCBI chr16:10,722,110...10,726,648
Ensembl chr16:10,722,106...10,726,707
JBrowse link
G Snw1 SNW domain containing 1 susceptibility ISO DNA:snp:intron: T>A (human) (rs1477261) RGD PMID:20056645 RGD:11035249 NCBI chr 6:111,483,698...111,507,782
Ensembl chr 6:111,483,703...111,507,782
JBrowse link
G Sod1 superoxide dismutase 1 ISO protein:decreased expression:pancreas RGD PMID:12499913 RGD:2317410 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 disease_progression
susceptibility
ISO protein:decreased expression:pancreas
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:cds:p.A16V (human)
CTD PMID:17895890, PMID:12499913, PMID:12700280, PMID:18205184 RGD:2317410, RGD:1581235, RGD:2317406 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19896093 NCBI chr18:38,221,919...38,242,092
Ensembl chr18:38,221,681...38,242,119
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15970685 RGD:1581363 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Sst somatostatin ISO CTD Direct Evidence: therapeutic CTD PMID:2868874 NCBI chr11:80,358,172...80,359,449
Ensembl chr11:80,358,211...80,359,444
JBrowse link
G Sstr1 somatostatin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17625444 NCBI chr 6:79,252,914...79,258,611
Ensembl chr 6:79,254,339...79,258,611
JBrowse link
G Sstr2 somatostatin receptor 2 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:15259086, PMID:17625444, PMID:19917848 NCBI chr10:102,136,283...102,143,449
Ensembl chr10:102,136,283...102,143,434
JBrowse link
G Sstr3 somatostatin receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17625444 NCBI chr 7:119,760,881...119,768,082
Ensembl chr 7:119,760,888...119,768,082
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22348037, PMID:23845849 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stk11 serine/threonine kinase 11 ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
PMID:26098869 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513
JBrowse link
G Sugct succinylCoA:glutarate-CoA transferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr17:49,991,314...51,030,950 JBrowse link
G Sycp1 synaptonemal complex protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14991579 NCBI chr 2:205,274,766...205,426,869
Ensembl chr 2:205,274,769...205,426,869
JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
G Tert telomerase reverse transcriptase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25086665, PMID:26098869 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16965396 NCBI chr 4:28,947,951...28,953,261
Ensembl chr 4:28,947,965...28,953,067
JBrowse link
G Tgfa transforming growth factor alpha ISO
IMP
mRNA, protein:increased expression:pancreas RGD PMID:1401070, PMID:19506583, PMID:17785207 RGD:2317473, RGD:5490965, RGD:2317468 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tgfb1 transforming growth factor, beta 1 disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
CTD PMID:23992306, PMID:18787407, PMID:16933058 RGD:2325015, RGD:2325018 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 disease_progression ISO DNA:deletion, frameshift mutations (human)
DNA:mutations:exon
protein:increased expresssion:pancreas
mRNA:increased expresssion:pancreas
RGD PMID:9850059, PMID:18772397, PMID:11866987, PMID:9365135 RGD:2317501, RGD:5490966, RGD:2317499, RGD:2317502 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Tgm2 transglutaminase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30108682 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
JBrowse link
G Thbs1 thrombospondin 1 disease_progression ISO DNA:hypermethylation (human) RGD PMID:10766168, PMID:20203415, PMID:16757110 RGD:2325028, RGD:2325021, RGD:2325023 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: therapeutic CTD PMID:16211219 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:11234897 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tp53 tumor protein p53 ISO DNA:mutations:exon
ClinVar Annotator: match by term: Pancreatic cancer
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:1565143, PMID:1565144, PMID:1683921, PMID:7732013, PMID:7887414, PMID:8164043, PMID:8198984, PMID:8203469, PMID:8423216, PMID:8825920, PMID:9047394, PMID:9242456, PMID:9569050, PMID:9865903, PMID:10411893, PMID:10797439, PMID:10864200, PMID:11040944, PMID:11101847, PMID:11139324, PMID:11391594, PMID:11479205, PMID:11782540, PMID:12007217, PMID:12619118, PMID:12672316, PMID:12826609, PMID:15004724, PMID:15173255, PMID:15381368, PMID:15390294, PMID:15580553, PMID:15607980, PMID:15607981, PMID:15951970, PMID:15977174, PMID:16401470, PMID:16489069, PMID:16682957, PMID:16818505, PMID:17224268, PMID:17289876, PMID:17540308, PMID:17606709, PMID:17636407, PMID:17727479, PMID:18391940, PMID:18511570, PMID:19127115, PMID:19367569, PMID:19556618, PMID:19881536, PMID:20113312, PMID:20128691, PMID:20407015, PMID:20516128, PMID:20689556, PMID:20693561, PMID:21187651, PMID:21232794, PMID:21305319, PMID:21343334, PMID:21484931, PMID:21512767, PMID:21519010, PMID:21552135, PMID:21601526, PMID:21761402, PMID:22006311, PMID:22110706, PMID:22186996, PMID:22233476, PMID:22652532, PMID:22698404, PMID:22710932, PMID:22811390, PMID:22899716, PMID:22915647, PMID:23161690, PMID:23246812, PMID:23263379, PMID:23484829, PMID:23538418, PMID:23792586, PMID:23873029, PMID:23894400, PMID:24033266, PMID:24381225, PMID:24487413, PMID:24501221, PMID:24573247, PMID:24641375, PMID:24651012, PMID:24677579, PMID:24728327, PMID:24810334, PMID:24868540, PMID:25157968, PMID:25527155, PMID:25584008, PMID:25741868, PMID:25787918, PMID:25952993, PMID:26086041, PMID:26230955, PMID:26390243, PMID:26467025, PMID:26585234, PMID:26619011, PMID:26681312, PMID:26822237, PMID:26845104, PMID:27153395, PMID:27276561, PMID:27374712, PMID:27463065, PMID:27516001, PMID:27680515, PMID:27683180, PMID:27895058, PMID:27959731, PMID:28125078, PMID:28349240, PMID:28369373, PMID:28453743, PMID:28492532, PMID:28772286, PMID:28861920, PMID:29478780, PMID:29489754, PMID:29945567, PMID:30076369, PMID:30224644, PMID:30287823, PMID:30327374, PMID:30374176, PMID:30883245, PMID:31016814, PMID:31159747, PMID:18772397 RGD:5490966 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 ISO RGD PMID:11585747 RGD:2325154 NCBI chr 3:113,160,030...113,259,701
Ensembl chr 3:113,160,000...113,231,790
JBrowse link
G Tp63 tumor protein p63 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
G Tsc2 TSC complex subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19917848 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
G Tymp thymidine phosphorylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17443278, PMID:19671868 RGD:2325156 NCBI chr 7:130,342,481...130,347,845
Ensembl chr 7:130,342,483...130,347,587
JBrowse link
G Tyms thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19020767 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Uck2 uridine-cytidine kinase 2 ISO protein:increased expression:pancreatic neoplasm (human) RGD PMID:12149149 RGD:5133269 NCBI chr13:85,376,716...85,443,976
Ensembl chr13:85,376,716...85,443,976
JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C no_association ISO DNA:polymorphisms: :p.N129K, p.R131K, p.W208R (human)
DNA:polymorphisms: :multiple (human)
RGD PMID:12806614, PMID:17072959 RGD:2317503, RGD:2317157 NCBI chr 9:95,233,957...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO RGD PMID:17652277 RGD:2325162 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vegfb vascular endothelial growth factor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:24604347 NCBI chr 1:222,237,000...222,242,786
Ensembl chr 1:222,239,022...222,242,644
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO DNA:hypermethylation, deletion:promoter (human)
associated with Hippel-Lindau Disease;DNA:missense mutation:exon:p.R238Q (human)
RGD PMID:19690016, PMID:9488521 RGD:2325169, RGD:2325176 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link
G Wnt9a Wnt family member 9A ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr10:45,659,045...45,686,103
Ensembl chr10:45,659,143...45,681,393
JBrowse link
G Wt1 WT1 transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19196508 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor ISO DNA:polymorphism:intron:AF076952 (human) RGD PMID:18559563 RGD:2317130 NCBI chr 4:123,134,457...123,161,985
Ensembl chr 4:123,134,457...123,161,985
JBrowse link
G Xpo5 exportin 5 ISO mRNA:decreased expression:pancreas (mouse) RGD PMID:26516699 RGD:11041739 NCBI chr 9:17,125,201...17,163,170
Ensembl chr 9:17,125,201...17,163,170
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 ISO DNA:SNP:exon:rs1799782 (human) RGD PMID:16520463 RGD:2317367 NCBI chr 1:81,412,635...81,441,680
Ensembl chr 1:81,413,353...81,441,678
JBrowse link
G Xrcc2 X-ray repair cross complementing 2 ISO DNA:polymorphism: :p.R188H (human)
DNA:SNP:exon:rs3218536 (human)
RGD PMID:17986315, PMID:16540687 RGD:2317507, RGD:2317365 NCBI chr 4:5,842,013...5,860,516
Ensembl chr 4:5,841,998...5,860,527
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 ISO DNA:SNP:cd:rs861539 (human) RGD PMID:18559563 RGD:2317130 NCBI chr 6:136,366,917...136,380,751
Ensembl chr 6:136,371,555...136,379,348
JBrowse link
G Znrf3 zinc and ring finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25086665, PMID:26098869 NCBI chr14:85,527,099...85,586,294 JBrowse link
pancreatic carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1b activin A receptor type 1B ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:11248065 NCBI chr 7:142,817,174...142,858,365
Ensembl chr 7:142,817,157...142,860,572
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr10:55,744,646...55,756,524
Ensembl chr10:55,744,588...55,756,566
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Brca1 BRCA1, DNA repair associated ISO ClinVar Annotator: match by term: Carcinoma of head of pancreas ClinVar PMID:25741868 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Cbr4 carbonyl reductase 4 ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:17194196, PMID:28492532 NCBI chr16:31,944,328...31,972,553
Ensembl chr16:31,956,753...31,972,507
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO RGD PMID:9252195 RGD:8662427 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A susceptibility ISO DNA:insertion:cds:p.R112_L113insR (human) RGD PMID:10922411 RGD:8552383 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Chd3 chromodomain helicase DNA binding protein 3 disease_progression IEP protein:increased expression:pancreas RGD PMID:21472101 RGD:9587766 NCBI chr10:55,943,467...55,970,417
Ensembl chr10:55,943,446...55,965,216
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 severity IEP protein:increased expression:pancreas (rat) RGD PMID:21472101 RGD:9587766 NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr19:29,592,889...30,341,528
Ensembl chr19:29,597,905...29,968,424
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISS
ISO
OMIM:260350
ClinVar Annotator: match by term: PANCREATIC CARCINOMA
MouseDO
ClinVar
PMID:2278970, PMID:3122217, PMID:7773929, PMID:8439212, PMID:12460918, PMID:15696205, PMID:15842656, PMID:16361624, PMID:16434492, PMID:16618717, PMID:17332249, PMID:17384584, PMID:17704260, PMID:17910045, PMID:18316791, PMID:18794081, PMID:19018267, PMID:19029981, PMID:19047918, PMID:19075190, PMID:19114683, PMID:19255327, PMID:19358724, PMID:19679400, PMID:19773371, PMID:19881948, PMID:20609353, PMID:20805368, PMID:20921462, PMID:20921465, PMID:20949522, PMID:21079152, PMID:21169357, PMID:21228335, PMID:21398618, PMID:21975775, PMID:22025163, PMID:22235099, PMID:22407852, PMID:22499344, PMID:22683711, PMID:22897852, PMID:23014527, PMID:23096712, PMID:23406027, PMID:24033266, PMID:25044103, PMID:25157968, PMID:25695684, PMID:26372703, PMID:28492532, PMID:29298116, PMID:31891627 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Mir155 microRNA 155 ISO miRNA:increased expression:serum RGD PMID:28660759 RGD:24922217 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment ISO RGD PMID:25425965 RGD:11570510 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISS OMIM:260350 MouseDO NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Palld palladin, cytoskeletal associated protein ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:17194196, PMID:28492532 NCBI chr16:31,865,712...31,948,168 JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase IEP mRNA:increased expression:pancreas (rat) RGD PMID:2278633 RGD:14392892 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rbbp8 RB binding protein 8, endonuclease ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:9811458 NCBI chr18:3,134,630...3,227,702
Ensembl chr18:3,162,543...3,227,688
JBrowse link
G Smad4 SMAD family member 4 ISO
ISS
ClinVar Annotator: match by term: Carcinoma of pancreas
ClinVar Annotator: match by term: PANCREATIC CARCINOMA
OMIM:260350
ClinVar
MouseDO
PMID:8653691, PMID:8898652, PMID:9679244, PMID:9811934, PMID:10479724, PMID:10764709, PMID:10775259, PMID:10797267, PMID:11274206, PMID:12821112, PMID:14715079, PMID:15014009, PMID:15031030, PMID:15235019, PMID:16152648, PMID:16613914, PMID:17873119, PMID:17994767, PMID:20101697, PMID:22331366, PMID:25741868, PMID:26619011, PMID:27595937, PMID:27978560, PMID:28135145, PMID:28492532 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11328670 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Stk11 serine/threonine kinase 11 ISO
ISS
ClinVar Annotator: match by term: Carcinoma of pancreas
OMIM:260350
ClinVar
MouseDO
PMID:10362809, PMID:11430832, PMID:23399955, PMID:24307375, PMID:25186627, PMID:25741868, PMID:26056085, PMID:26467025, PMID:28135145, PMID:28492532, PMID:30287823, PMID:32566746 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513
JBrowse link
G Tp53 tumor protein p53 ISO
ISS
ClinVar Annotator: match by term: Carcinoma of pancreas
ClinVar Annotator: match by term: PANCREATIC CARCINOMA
OMIM:260350
ClinVar
MouseDO
PMID:1565143, PMID:1565144, PMID:1683921, PMID:7732013, PMID:7887414, PMID:8164043, PMID:8198984, PMID:8203469, PMID:8423216, PMID:8513440, PMID:8825920, PMID:9047394, PMID:9242456, PMID:9569050, PMID:9865903, PMID:10411893, PMID:10797439, PMID:10864200, PMID:11040944, PMID:11101847, PMID:11139324, PMID:11391594, PMID:11479205, PMID:11782540, PMID:12007217, PMID:12619118, PMID:12672316, PMID:12826609, PMID:15004724, PMID:15173255, PMID:15381368, PMID:15390294, PMID:15580553, PMID:15607980, PMID:15607981, PMID:15951970, PMID:15977174, PMID:16401470, PMID:16489069, PMID:16682957, PMID:16818505, PMID:17224268, PMID:17289876, PMID:17540308, PMID:17606709, PMID:17636407, PMID:17727479, PMID:18391940, PMID:18511570, PMID:19127115, PMID:19367569, PMID:19556618, PMID:19881536, PMID:20113312, PMID:20128691, PMID:20407015, PMID:20516128, PMID:20689556, PMID:20693561, PMID:21187651, PMID:21232794, PMID:21305319, PMID:21343334, PMID:21484931, PMID:21512767, PMID:21519010, PMID:21552135, PMID:21601526, PMID:21761402, PMID:22006311, PMID:22110706, PMID:22186996, PMID:22233476, PMID:22652532, PMID:22698404, PMID:22710932, PMID:22811390, PMID:22899716, PMID:22915647, PMID:23161690, PMID:23246812, PMID:23263379, PMID:23484829, PMID:23538418, PMID:23792586, PMID:23894400, PMID:24033266, PMID:24381225, PMID:24487413, PMID:24501221, PMID:24573247, PMID:24641375, PMID:24651012, PMID:24677579, PMID:24728327, PMID:24810334, PMID:24868540, PMID:25157968, PMID:25527155, PMID:25584008, PMID:25741868, PMID:25787918, PMID:25952993, PMID:26086041, PMID:26230955, PMID:26467025, PMID:26585234, PMID:26619011, PMID:26681312, PMID:26822237, PMID:26845104, PMID:27153395, PMID:27276561, PMID:27374712, PMID:27463065, PMID:27516001, PMID:27680515, PMID:27683180, PMID:27895058, PMID:27959731, PMID:28125078, PMID:28349240, PMID:28369373, PMID:28453743, PMID:28492532, PMID:28772286, PMID:28861920, PMID:29478780, PMID:29489754, PMID:29945567, PMID:30076369, PMID:30224644, PMID:30287823, PMID:30327374, PMID:30374176, PMID:30883245, PMID:31016814, PMID:31159747 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tsc1 TSC complex subunit 1 ISO RGD PMID:25425965 RGD:11570510 NCBI chr 3:7,219,955...7,269,063
Ensembl chr 3:7,237,192...7,265,145
JBrowse link
pancreatic ductal adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member ISO protein:increased expression:pancreas RGD PMID:19714807 RGD:2325658 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 ISO protein:increased expression:pancreas RGD PMID:19077459 RGD:2325696 NCBI chr 5:157,759,448...157,768,473
Ensembl chr 5:157,759,416...157,768,471
JBrowse link
G Ccnd1 cyclin D1 severity ISO DNA:snp:exon:c.870G>A (human)
protein:increased expression:pancreas (human)
RGD PMID:25470788, PMID:22939953 RGD:13462050, RGD:13462062 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdk4 cyclin-dependent kinase 4 severity ISO protein:increased expression:pancreas, islet of Langerhans (human) RGD PMID:29735403 RGD:13781899 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G E2f1 E2F transcription factor 1 severity ISO protein:increased expression:pancreatic ductal cell, nucleus (human)
DNA:amplification: : (human)
RGD PMID:12650514, PMID:17233815, PMID:27573434 RGD:13838735, RGD:13838739, RGD:13838738 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 treatment ISO human cells in a mouse model RGD PMID:23535601 RGD:13504844 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta susceptibility ISO RGD PMID:22264792 RGD:13838741 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Jak1 Janus kinase 1 ISO mRNA:decreased expression:pancreatic ductal cell (human) RGD PMID:28677798 RGD:13838745 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 severity
disease_progression
ISO protein:increased phosphorylation:pancreas (mouse) RGD PMID:28837246, PMID:23237571 RGD:14348974, RGD:14348975 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mir155 microRNA 155 disease_progression ISO RGD PMID:28198398 RGD:25314300 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Pgf placental growth factor severity ISO associated with obesity RGD PMID:26861455 RGD:14349030 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO mRNA, protein:increased expression:pancreas (human) RGD PMID:20876794 RGD:14390130 NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337
JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 severity ISO human cells in a mouse model RGD PMID:15591514 RGD:14390084 NCBI chr16:20,415,109...20,424,982
Ensembl chr16:20,416,432...20,424,980
JBrowse link
G Pld1 phospholipase D1 severity ISO protein:increased expression:pancreas (human) RGD PMID:27713167 RGD:14392801 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403
JBrowse link
G Rac1 Rac family small GTPase 1 ISO mRNA:increased expression:pancreas (human)
mRNA, protein:increased expression:pancreas (mouse)
RGD PMID:23334332, PMID:21684285 RGD:14392806, RGD:14392816 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rala RAS like proto-oncogene A ISO mRNA:increased expression:pancreas (human) RGD PMID:29113235 RGD:14394418 NCBI chr17:49,676,073...49,729,133
Ensembl chr17:49,714,294...49,727,664
JBrowse link
G Smad2 SMAD family member 2 severity ISO RGD PMID:26908446 RGD:14394493 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
pancreatic ductal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO mRNA, protein:increased expression:pancreas RGD PMID:17481528 RGD:2325211 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 ISO protein:decreased expression:pancreas RGD PMID:19212105 RGD:2325210 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 disease_progression ISO mRNA:increased expression:pancreas RGD PMID:17979891 RGD:2325243 NCBI chr 1:212,317,510...212,332,895
Ensembl chr 1:212,317,848...212,330,349
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 disease_progression ISO protein:altered localization:cytoplasm RGD PMID:14997207 RGD:2325249 NCBI chr16:71,810,377...71,887,926
Ensembl chr16:71,810,377...71,887,926
JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member ISO mRNA:increased expression:pancreas RGD PMID:19609859 RGD:2325659 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO CTD Direct Evidence: marker/mechanism CTD PMID:17481528 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Alb albumin disease_progression ISO RGD PMID:19011933 RGD:2325677 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Anxa2 annexin A2 disease_progression ISO mRNA, protein:increased expression, altered localization:pancreas, plasma membrane RGD PMID:19260470, PMID:16450333 RGD:2317307, RGD:2325731 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Anxa5 annexin A5 ISO protein:increased expression:pancreas RGD PMID:19488907 RGD:2317538 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Anxa8 annexin A8 ISO mRNA:increased expression:pancreas RGD PMID:18223320 RGD:2325735 NCBI chr16:10,417,174...10,432,388
Ensembl chr16:10,417,185...10,432,393
JBrowse link
G Apoc1 apolipoprotein C1 ISO RGD PMID:15876873 RGD:2325793 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G Arg2 arginase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23424623 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger ISO protein:increased expression:pancreas
protein:increased expression:exocrine pancreas:
RGD PMID:19585519, PMID:19585519 RGD:9491843, RGD:9491843 NCBI chr17:85,360,439...85,370,283
Ensembl chr17:85,364,483...85,368,208
JBrowse link
G Calr calreticulin ISO protein:increased expression:pancreatic duct RGD PMID:15289361 RGD:2326165 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Cbx7 chromobox 7 disease_progression ISO protein:decreased expression:pancreas RGD PMID:20185297 RGD:9587360 NCBI chr 7:121,136,067...121,153,503
Ensembl chr 7:121,136,058...121,153,383
JBrowse link
G Cckar cholecystokinin A receptor ISO mRNA:increased expression:pancreatic duct
protein:decreased expression:pancreas
RGD PMID:9239407, PMID:12851875 RGD:4110818, RGD:4110816 NCBI chr14:59,610,939...59,619,786
Ensembl chr14:59,611,434...59,619,783
JBrowse link
G Cckbr cholecystokinin B receptor ISO protein:decreased expression:pancreas RGD PMID:12851875 RGD:4110816 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
JBrowse link
G Ccnd1 cyclin D1 severity ISO protein:increased expression:pancreas (human) RGD PMID:17420962 RGD:13462063 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cd40 CD40 molecule treatment ISO protein:increased expression:dendritic cell RGD PMID:21436454, PMID:23983255, PMID:20976171 RGD:5490301, RGD:11522743, RGD:5490524 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cdk6 cyclin-dependent kinase 6 treatment ISO human cells in a mouse model RGD PMID:24389175 RGD:13782187 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A disease_progression ISO RGD PMID:17671118 RGD:8662851 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:24986516 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cldn4 claudin 4 ISO RGD PMID:15693851 RGD:2317592 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
JBrowse link
G Dnmt1 DNA methyltransferase 1 disease_progression ISO protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
CTD PMID:29844410, PMID:19424621 RGD:9588974 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta disease_progression ISO RGD PMID:22919364 RGD:9589121 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Dtx1 deltex E3 ubiquitin ligase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr12:41,383,885...41,415,783
Ensembl chr12:41,385,241...41,414,754
JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 1:228,729,842...228,759,783
Ensembl chr 1:228,732,985...228,755,866
JBrowse link
G Egf epidermal growth factor disease_progression ISO protein:increased expression: : RGD PMID:18505086 RGD:2317644 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Faslg Fas ligand ISO protein:increased expression:pancreas, liver RGD PMID:10547193, PMID:15375495 RGD:2317747, RGD:2317741 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fgf2 fibroblast growth factor 2 disease_progression ISO RGD PMID:12717266, PMID:18704599 RGD:2317758, RGD:2317756 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fscn1 fascin actin-bundling protein 1 disease_progression ISO protein:increased expression:pancreas RGD PMID:12109856 RGD:2317790 NCBI chr12:13,655,459...13,668,595
Ensembl chr12:13,656,554...13,668,515
JBrowse link
G Gpnmb glycoprotein nmb ISO CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gstp1 glutathione S-transferase pi 1 resistance ISO DNA:methylation: :
mRNA, protein:increased expression:pancreas
RGD PMID:16537562, PMID:17265526, PMID:12488200 RGD:2317809, RGD:2317806, RGD:2317811 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hdac1 histone deacetylase 1 disease_progression ISO protein:increased expression:pancreas RGD PMID:19424621 RGD:9588974 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Heatr1 HEAT repeat containing 1 treatment ISO RGD PMID:26676747 RGD:10761108 NCBI chr17:66,446,135...66,488,303
Ensembl chr17:66,446,162...66,619,250
JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17234771 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17234771 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Igf1 insulin-like growth factor 1 ISO RGD PMID:20098680 RGD:2317639 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor ISO protein:increased expression:pancreas RGD PMID:14627343, PMID:14506643 RGD:2317649, RGD:2317652 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Il4 interleukin 4 ISO RGD PMID:17942922 RGD:2317264 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4r interleukin 4 receptor ISO protein:increased expression:pancreas RGD PMID:17942922 RGD:2317264 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Ins2 insulin 2 ISO Glucagon/insulin RGD PMID:19571666 RGD:2317248 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Jag1 jagged canonical Notch ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Jag2 jagged canonical Notch ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 6:137,711,144...137,733,331
Ensembl chr 6:137,711,155...137,733,026
JBrowse link
G Kdm2b lysine demethylase 2B severity ISO mRNA, protein:increased expression:pancreas (human) RGD PMID:23321669 RGD:9588253 NCBI chr12:39,021,924...39,161,954
Ensembl chr12:39,078,119...39,161,956
JBrowse link
G Kitlg KIT ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25347530, PMID:30654191 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Krt7 keratin 7 disease_progression ISO RGD PMID:19260470 RGD:2317307 NCBI chr 7:143,059,731...143,075,907
Ensembl chr 7:143,059,764...143,075,907
JBrowse link
G L1cam L1 cell adhesion molecule severity ISO protein:increased expression:pancreas (human) RGD PMID:20162456 RGD:6483447 NCBI chr  X:156,901,244...156,928,064
Ensembl chr  X:156,909,913...156,928,057
JBrowse link
G Mapk3 mitogen activated protein kinase 3 treatment ISO human cells in mouse model RGD PMID:20179210 RGD:14348973 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 ISO mRNA, protein:increased expression:pancreatic duct RGD PMID:15548371 RGD:2317697 NCBI chr12:19,306,615...19,313,877
Ensembl chr12:19,306,607...19,314,016
JBrowse link
G Mdm2 MDM2 proto-oncogene onset
severity
ISO DNA:snp:promoter, intron:IVS1+309T>G (human)
protein:increased expression:pancreas (human)
RGD PMID:19752772, PMID:15810085 RGD:2317414, RGD:2317416 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Men1 menin 1 ISO protein:decreased expression:pancreas RGD PMID:19170121 RGD:2317294 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO protein:increased expression:pancreatic duct (human) RGD PMID:7866999 RGD:2317530 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase susceptibility ISO DNA:missense mutation:cds:p.L84F rs12917 (human)
protein:increased activity, increased expression:ductal adenocarcinoma (human)
RGD PMID:16844323, PMID:9393761 RGD:2317648, RGD:2317664 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mir142 microRNA 142 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29844410 NCBI chr10:75,050,839...75,050,925
Ensembl chr10:75,050,832...75,050,942
JBrowse link
G Mir873 microRNA 873 ISO CTD Direct Evidence: therapeutic CTD PMID:30654191 NCBI chr 5:52,481,076...52,481,152
Ensembl chr 5:52,481,076...52,481,152
JBrowse link
G Mmp2 matrix metallopeptidase 2 severity ISO protein:increased expression:pancreas RGD PMID:17377415 RGD:2325746 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased expression:pancreas, serum
protein:increased expression:blood
RGD PMID:18706098, PMID:20332475 RGD:2325844, RGD:2325830 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Msln mesothelin disease_progression ISO protein:increased secretion:serum
CTD Direct Evidence: marker/mechanism
DNA:hypomethylation:5'UTR
CTD PMID:14576474, PMID:21775916, PMID:25347530, PMID:19818733, PMID:12874021 RGD:2326055, RGD:2326065 NCBI chr10:15,119,700...15,129,129
Ensembl chr10:15,119,663...15,125,408
JBrowse link
G Muc1 mucin 1, cell surface associated disease_progression ISO protein:increased expression, altered localization:pancreas RGD PMID:14681945, PMID:19109152, PMID:18713982 RGD:2317983, RGD:2324616, RGD:2324633 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Muc3 mucin 3, intestinal disease_progression ISO mRNA:increased expression:pancreas RGD PMID:12657964 RGD:2324946 NCBI chr12:22,535,663...22,584,775 JBrowse link
G Muc4 mucin 4, cell surface associated disease_progression ISO mRNA:increased expression:pancreas
protein:increased expression:pancreas
RGD PMID:12657964, PMID:16049287 RGD:2324946, RGD:2324942 NCBI chr11:71,242,973...71,285,217
Ensembl chr11:71,243,334...71,284,939
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming disease_progression ISO mRNA:increased expression:pancreas RGD PMID:7657125, PMID:10227724 RGD:2324986, RGD:2324907 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming ISO mRNA:increased expression:pancreas RGD PMID:7657125 RGD:2324986 NCBI chr 1:214,778,459...214,811,237
Ensembl chr 1:214,778,496...214,810,720
JBrowse link
G Ndrg1 N-myc downstream regulated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16778198 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21489257 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 ISO protein:increased expression:pancreas (human) RGD PMID:17492507 RGD:5132867 NCBI chr10:81,657,152...81,666,542
Ensembl chr10:81,657,153...81,666,523
JBrowse link
G Nos2 nitric oxide synthase 2 ISO RGD PMID:12660813 RGD:2325254 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Notch1 notch receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345, PMID:20484026, PMID:19028876 RGD:2325323, RGD:2325324 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Notch3 notch receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 7:14,138,495...14,189,688
Ensembl chr 7:14,138,495...14,189,688
JBrowse link
G Notch4 notch receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr20:4,329,794...4,353,868
Ensembl chr20:4,329,811...4,353,785
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 disease_progression ISO protein:increased expression:pancreas RGD PMID:11295066, PMID:10209957 RGD:2325660, RGD:2325663 NCBI chr 1:139,890,537...140,262,503
Ensembl chr 1:139,890,560...140,262,503
JBrowse link
G Osm oncostatin M ISO CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr14:84,457,487...84,469,426
Ensembl chr14:84,465,515...84,470,409
JBrowse link
G Palld palladin, cytoskeletal associated protein ISO protein:increased expression, alternative form:pancreas, fibroblast RGD PMID:17404500 RGD:2325781 NCBI chr16:31,865,712...31,948,168 JBrowse link
G Pax6 paired box 6 ISO protein:increased expression:pancreatic duct (human) RGD PMID:17849422 RGD:8552381 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624
JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component ISO protein:increased expression:pancreatic duct RGD PMID:15856462 RGD:2324870 NCBI chr 9:53,120,656...53,206,520
Ensembl chr 9:53,120,656...53,206,516
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma disease_progression ISO RGD PMID:19396032 RGD:2317461 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:18670639 RGD:2317185 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rnf2 ring finger protein 2 ISO protein:increased expression:pancreas RGD PMID:19585519 RGD:9491843 NCBI chr13:68,829,714...68,859,920
Ensembl chr13:68,830,620...68,858,809
JBrowse link
G Rxra retinoid X receptor alpha severity ISO RGD PMID:19396032 RGD:2317461 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Serpina1 serpin family A member 1 ISO mRNA, protein:increased expression:pancreas RGD PMID:12488200 RGD:2317811 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO protein:increased expression:pancreatic duct RGD PMID:19252908 RGD:2324975 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Smad4 SMAD family member 4 disease_progression ISO RGD PMID:15173084 RGD:21066334 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Smo smoothened, frizzled class receptor ISO RGD PMID:16826192 RGD:2324981 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770
JBrowse link
G Stk11 serine/threonine kinase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26887594 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513
JBrowse link
G Tgfb1 transforming growth factor, beta 1 disease_progression ISO RGD PMID:16101174 RGD:2325019 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 disease_progression ISO mRNA:increased expresssion:pancreas RGD PMID:17114585, PMID:10547197 RGD:2317498, RGD:2317500 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Thbs1 thrombospondin 1 disease_progression ISO DNA:hypermethylation:promoter (human) RGD PMID:12429967, PMID:19065635 RGD:2325025, RGD:2325022 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Tmprss3 transmembrane serine protease 3 ISO RGD PMID:14695172 RGD:2325152 NCBI chr20:9,910,522...9,929,705
Ensembl chr20:9,910,522...9,929,705
JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29844410 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tsc2 TSC complex subunit 2 severity ISO RGD PMID:16213898 RGD:11568674 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
G Tymp thymidine phosphorylase disease_progression ISO RGD PMID:19760965 RGD:2325155 NCBI chr 7:130,342,481...130,347,845
Ensembl chr 7:130,342,483...130,347,587
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17481528 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO DNA:hypermethylation:promoter (human) RGD PMID:19065635 RGD:2325022 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link
pancreatic endocrine carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated ISO ClinVar Annotator: match by term: Neuroendocrine tumor of pancreas ClinVar PMID:15145354, PMID:25741868 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748
JBrowse link
G Daxx death-domain associated protein ISO protein:decreased expression:pancreas: RGD PMID:23954140 RGD:9587816 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO DNA:hypermethylation:promoter (human) RGD PMID:14501508 RGD:2317661 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Palb2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: Neuroendocrine tumor of pancreas ClinVar PMID:25741868 NCBI chr 1:192,064,586...192,088,547
Ensembl chr 1:192,064,589...192,088,520
JBrowse link
G Pgf placental growth factor disease_progression
treatment
ISO protein:increased expression:serum (human)
human cells in a mouse model
RGD PMID:23463017, PMID:26861455 RGD:14349029, RGD:14349030 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
pancreatic intraductal papillary-mucinous neoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO DNA:missense mutation:cds:p.E17K (human) RGD PMID:24132918 RGD:13462042 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Tp53 tumor protein p53 ISO DNA:missense mutations: :multiple RGD PMID:28930868 RGD:14995501 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
Pancreatic Intraepithelial Neoplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member ISO protein:increased expression:pancreas RGD PMID:19714807 RGD:2325658 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger ISO protein:increased expression:pancreatic acinar cell:
protein:increased expression:exocrine pancreas:
RGD PMID:19585519, PMID:19585519 RGD:9491843, RGD:9491843 NCBI chr17:85,360,439...85,370,283
Ensembl chr17:85,364,483...85,368,208
JBrowse link
G Cbx7 chromobox 7 disease_progression ISO protein:decreased expression:pancreas RGD PMID:20185297 RGD:9587360 NCBI chr 7:121,136,067...121,153,503
Ensembl chr 7:121,136,058...121,153,383
JBrowse link
G Ccnd1 cyclin D1 disease_progression ISO protein:increased expression:pancreas (human) RGD PMID:12882690, PMID:11751405 RGD:13462061, RGD:13464129 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO protein:increased expression:pancreas RGD PMID:19424621 RGD:9588974 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Hdac1 histone deacetylase 1 ISO protein:increased expression:pancreas RGD PMID:19424621 RGD:9588974 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta severity
disease_progression
ISO RGD PMID:22406536, PMID:22056382 RGD:13838740, RGD:13838742 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
Pancreatic Islet Cell Tumors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler disease_progression ISO protein:decreased expression:pancreas: RGD PMID:24148618 RGD:9586032 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878
JBrowse link
G Cdk4 cyclin-dependent kinase 4 ISO protein:increased expression:pancreas, islet of Langerhans (human) RGD PMID:22761470 RGD:13452384 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Daxx death-domain associated protein disease_progression ISO RGD PMID:21252315 RGD:9587819 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926
JBrowse link
pancreatic mucinous cystadenoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kras KRAS proto-oncogene, GTPase severity ISO DNA:mutations:cds: RGD PMID:28570009 RGD:14398747 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
pancreatic solid pseudopapillary carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 severity ISO protein:increased expression:pancreas (human) RGD PMID:19248223 RGD:13462054 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
vipoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Men1 menin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17961653 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
G Sst somatostatin ISO CTD Direct Evidence: therapeutic CTD PMID:2868874 NCBI chr11:80,358,172...80,359,449
Ensembl chr11:80,358,211...80,359,444
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16103
    disease of anatomical entity 15351
      endocrine system disease 4986
        pancreas disease 1106
          Pancreatic Neoplasms 387
            Pancreatic Benign Neoplasm + 13
            Pancreatic Islet Cell Tumors + 31
            pancreatic cancer + 379
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.