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Term:Neonatal Alloimmune Thrombocytopenia
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Accession:DOID:9003340 term browser browse the term
Definition:A condition in newborns caused by immunity of the mother to PLATELET ALLOANTIGENS on the fetal platelets. The PLATELETS, coated with maternal ANTIBODIES, are destroyed and removed by the fetal MONONUCLEAR PHAGOCYTE SYSTEM. Affected infants may have INTRACRANIAL HEMORRHAGES.
Synonyms:exact_synonym: FETAL AND NEONATAL ALLOIMMUNE THROMBOCYTOPENIA;   NAIT;   Neonatal Alloimmune Thrombocytopenias;   Neonatal Thrombocytopenia;   Neonatal Thrombocytopenias
 related_synonym: BAK PLATELET-SPECIFIC ANTIGEN;   Ca/Tu Alloantigen Polymorphism;   Mo Alloantigen Polymorphism;   PEN(a)/PEN(b) Alloantigen Polymorphism
 primary_id: MESH:D054098
 alt_id: RDO:0007658
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Neonatal Alloimmune Thrombocytopenia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Itga2b integrin subunit alpha 2b JBrowse link 10 90,397,960 90,416,550 RGD:8554872
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:11554173

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Term Annotations click to browse term
  disease 14759
    Developmental Diseases 7628
      Congenital, Hereditary, and Neonatal Diseases and Abnormalities 6666
        Infant, Newborn, Diseases 403
          Neonatal Alloimmune Thrombocytopenia 2
Path 2
Term Annotations click to browse term
  disease 14759
    disease of anatomical entity 13978
      Hemic and Lymphatic Diseases 1573
        hematopoietic system disease 1355
          blood coagulation disease 389
            hemorrhagic disease 375
              blood platelet disease 192
                thrombocytopenia 128
                  thrombocytopenia due to platelet alloimmunization 3
                    Neonatal Alloimmune Thrombocytopenia 2
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